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The map label for this gene is nuoN1 [H]

Identifier: 225852331

GI number: 225852331

Start: 814149

End: 815585

Strand: Direct

Name: nuoN1 [H]

Synonym: BMEA_A0857

Alternate gene names: 225852331

Gene position: 814149-815585 (Clockwise)

Preceding gene: 225852330

Following gene: 225852332

Centisome position: 38.3

GC content: 56.99

Gene sequence:

>1437_bases
ATGCAGACTGATCTGTTAGCTCATCTGACCCTGGCAGCACCGGAGGTTCTCCTTGCTGTAGGCGCCTTGGCACGGCTCAT
GATCGGCGTGTTTTCTGGCGAACGGGCAACCACGCTCGTCAATGGATTGTCCGTCGCTGTGCTGATTGCGGCATTGGCTC
TGGTGCTTCTGGTTCCCGCAAACGGCACGGTTTTCGGTGGTGCGTTCGTCATTGACGGCTTTAGCCGCTTCATGAAGGTG
CTGACGCTGCTCGGATCCATTGTGGCGCTCATCATGTCGGTTGGCTTTGCCAAGGCGGAGAAATTCGACAAGTTCGAGTT
CCCGGTGCTGATCGTGATTGCCACGCTCGGCATGCTCCTGATGGTTTCGGCCAATAGCATGCTGACGCTTTATCTGGGTC
TCGAACTGCAATCGCTGGCGCTCTATGTTCTGGCGGCGTTCAACCGTGATAGCGTTCGTTCCACAGAAGCAGGCCTCAAA
TATTTTGTGCTGGGTTCGCTTTCTTCGGGCATGTTGCTCTATGGCATATCGCTCGTTTACGGCTATACCGGCCATATCGG
CTTCGTGGAAATCGCGCAGGCTGTTTCGGGTGGCCAGCGCGAGCTTGGCTTGGTGTTCGGCCTCATCTTCATCCTTGCCG
GTCTTGTATTCAAGATTTCCGCCGTTCCGTTCCACATGTGGACGCCGGACGTTTATGAAGGCGCTCCGACCCCGGTAACG
GCATTCTTTGCCGGGGCACCGAAGATGGCCGCCATGGCGCTCATCATTCGTGTTGTGACTGAGGCTTTTGCTCCGGTTAC
GCATGACTGGCAGCAGGTTATCATCTTCGTTGCACTCGCCTCCATGGTGTTGGGCGCGTTCGCCGCGATCGGCCAGCGCA
ACGTCAAGCGCCTGATGGCCTATTCCTCGATCAGCCATATGGGTTATGCGCTCGTTGGTCTGGCTGCGGGCACGGTTATC
GGCGTCAAGGGCGTGATGATCTATATGGCGATCTATCTCGCCATGACGCTCGGCAGCTTCGCTTTCATTCTTGCCATGCG
CATCAAGGACGGCAACGTCGAAAACATCGACGATCTGGCTGGTCTGTCGCGCACCAATCCGGTGCTGGCAACGGTCATGA
CCATCTTCCTGTTTTCGCTTGCAGGCATTCCGCCGCTGGCAGGCTTCTTCGGCAAGTGGTACACCTTCCTTGCCGCCGTG
GAAGCAGGCCTTTATCCGCTTGCCATCATCGGTATCGTGGCTTCGGTCGTGGGCGCGTTCTACTATCTGCGCATGATCAA
GATCATGTGGTTCGATGAACCGGCAGCGGGTTTTGTTCCGGTCGCGGGCGAGCTTCGCCTCGTACTCGGCGTAACAGGTG
CCTTCGTGCTTTTCTATGTCTTCCTTGCTGGCCCGATTGGCGGATATGCCGAAGCCGCAGCCAGGACGTTTTTCTAA

Upstream 100 bases:

>100_bases
CGCCGGTGCCGTGAACGCCTTGATCCAACATTACGATGCAGCTCTCGCGGCCAACGCGAGCGCCATGCTGGTCCAATAAG
AGAATAGAGGCGTAAAGGTC

Downstream 100 bases:

>100_bases
TCAAAGCTTGGGGGCGGAAGCTGAGATGAGTTTTGCGCTTTCGCCGGTGGCGGCAAATGAGGGCTACCGTCTCGAAACTT
TCGAGGCGGTAGGTTCCACC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N 1; NDH-1 subunit N 1 [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MQTDLLAHLTLAAPEVLLAVGALARLMIGVFSGERATTLVNGLSVAVLIAALALVLLVPANGTVFGGAFVIDGFSRFMKV
LTLLGSIVALIMSVGFAKAEKFDKFEFPVLIVIATLGMLLMVSANSMLTLYLGLELQSLALYVLAAFNRDSVRSTEAGLK
YFVLGSLSSGMLLYGISLVYGYTGHIGFVEIAQAVSGGQRELGLVFGLIFILAGLVFKISAVPFHMWTPDVYEGAPTPVT
AFFAGAPKMAAMALIIRVVTEAFAPVTHDWQQVIIFVALASMVLGAFAAIGQRNVKRLMAYSSISHMGYALVGLAAGTVI
GVKGVMIYMAIYLAMTLGSFAFILAMRIKDGNVENIDDLAGLSRTNPVLATVMTIFLFSLAGIPPLAGFFGKWYTFLAAV
EAGLYPLAIIGIVASVVGAFYYLRMIKIMWFDEPAAGFVPVAGELRLVLGVTGAFVLFYVFLAGPIGGYAEAAARTFF

Sequences:

>Translated_478_residues
MQTDLLAHLTLAAPEVLLAVGALARLMIGVFSGERATTLVNGLSVAVLIAALALVLLVPANGTVFGGAFVIDGFSRFMKV
LTLLGSIVALIMSVGFAKAEKFDKFEFPVLIVIATLGMLLMVSANSMLTLYLGLELQSLALYVLAAFNRDSVRSTEAGLK
YFVLGSLSSGMLLYGISLVYGYTGHIGFVEIAQAVSGGQRELGLVFGLIFILAGLVFKISAVPFHMWTPDVYEGAPTPVT
AFFAGAPKMAAMALIIRVVTEAFAPVTHDWQQVIIFVALASMVLGAFAAIGQRNVKRLMAYSSISHMGYALVGLAAGTVI
GVKGVMIYMAIYLAMTLGSFAFILAMRIKDGNVENIDDLAGLSRTNPVLATVMTIFLFSLAGIPPLAGFFGKWYTFLAAV
EAGLYPLAIIGIVASVVGAFYYLRMIKIMWFDEPAAGFVPVAGELRLVLGVTGAFVLFYVFLAGPIGGYAEAAARTFF
>Mature_478_residues
MQTDLLAHLTLAAPEVLLAVGALARLMIGVFSGERATTLVNGLSVAVLIAALALVLLVPANGTVFGGAFVIDGFSRFMKV
LTLLGSIVALIMSVGFAKAEKFDKFEFPVLIVIATLGMLLMVSANSMLTLYLGLELQSLALYVLAAFNRDSVRSTEAGLK
YFVLGSLSSGMLLYGISLVYGYTGHIGFVEIAQAVSGGQRELGLVFGLIFILAGLVFKISAVPFHMWTPDVYEGAPTPVT
AFFAGAPKMAAMALIIRVVTEAFAPVTHDWQQVIIFVALASMVLGAFAAIGQRNVKRLMAYSSISHMGYALVGLAAGTVI
GVKGVMIYMAIYLAMTLGSFAFILAMRIKDGNVENIDDLAGLSRTNPVLATVMTIFLFSLAGIPPLAGFFGKWYTFLAAV
EAGLYPLAIIGIVASVVGAFYYLRMIKIMWFDEPAAGFVPVAGELRLVLGVTGAFVLFYVFLAGPIGGYAEAAARTFF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=371, Percent_Identity=37.7358490566038, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI1788614, Length=370, Percent_Identity=27.8378378378378, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788831, Length=392, Percent_Identity=26.2755102040816, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788827, Length=295, Percent_Identity=26.1016949152542, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788613, Length=333, Percent_Identity=24.9249249249249, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788829, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 50684; Mature: 50684

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDLLAHLTLAAPEVLLAVGALARLMIGVFSGERATTLVNGLSVAVLIAALALVLLVPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECC
NGTVFGGAFVIDGFSRFMKVLTLLGSIVALIMSVGFAKAEKFDKFEFPVLIVIATLGMLL
CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHH
MVSANSMLTLYLGLELQSLALYVLAAFNRDSVRSTEAGLKYFVLGSLSSGMLLYGISLVY
HHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHCCEEEEEECCCCCHHHHHHHHHH
GYTGHIGFVEIAQAVSGGQRELGLVFGLIFILAGLVFKISAVPFHMWTPDVYEGAPTPVT
HCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHCCCCCCCHH
AFFAGAPKMAAMALIIRVVTEAFAPVTHDWQQVIIFVALASMVLGAFAAIGQRNVKRLMA
HHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSSISHMGYALVGLAAGTVIGVKGVMIYMAIYLAMTLGSFAFILAMRIKDGNVENIDDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
GLSRTNPVLATVMTIFLFSLAGIPPLAGFFGKWYTFLAAVEAGLYPLAIIGIVASVVGAF
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
YYLRMIKIMWFDEPAAGFVPVAGELRLVLGVTGAFVLFYVFLAGPIGGYAEAAARTFF
HHHHHHHHHEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure
MQTDLLAHLTLAAPEVLLAVGALARLMIGVFSGERATTLVNGLSVAVLIAALALVLLVPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECC
NGTVFGGAFVIDGFSRFMKVLTLLGSIVALIMSVGFAKAEKFDKFEFPVLIVIATLGMLL
CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHH
MVSANSMLTLYLGLELQSLALYVLAAFNRDSVRSTEAGLKYFVLGSLSSGMLLYGISLVY
HHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHCCEEEEEECCCCCHHHHHHHHHH
GYTGHIGFVEIAQAVSGGQRELGLVFGLIFILAGLVFKISAVPFHMWTPDVYEGAPTPVT
HCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHCCCCCCCHH
AFFAGAPKMAAMALIIRVVTEAFAPVTHDWQQVIIFVALASMVLGAFAAIGQRNVKRLMA
HHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSSISHMGYALVGLAAGTVIGVKGVMIYMAIYLAMTLGSFAFILAMRIKDGNVENIDDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
GLSRTNPVLATVMTIFLFSLAGIPPLAGFFGKWYTFLAAVEAGLYPLAIIGIVASVVGAF
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
YYLRMIKIMWFDEPAAGFVPVAGELRLVLGVTGAFVLFYVFLAGPIGGYAEAAARTFF
HHHHHHHHHEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]