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The map label for this gene is ureB

Identifier: 225851818

GI number: 225851818

Start: 296525

End: 296830

Strand: Direct

Name: ureB

Synonym: BMEA_A0302

Alternate gene names: 225851818

Gene position: 296525-296830 (Clockwise)

Preceding gene: 225851817

Following gene: 225851819

Centisome position: 13.95

GC content: 57.84

Gene sequence:

>306_bases
ATGATCCCAGGAGAAATCATTACGCTGGAAGGCGATATAGAGCTCAATCAGGGCCAGCCGACCGTTACGATGCGGGTTGC
CAATACCGGCGACCGCCCAATTCAGGTTGGCAGCCACTTCCATTTTTATGAGGTGAATGCCGCCCTTTCCTTCGATCGTG
AGAAGGCGCGCGGCCAGCGGCTCGATATAGCCGCCGGCACCGCCGTTCGCTTCGAGCCGGGGCAGGAACGCGATGTGACG
CTCGTTCCCATCAGGGGCCATCGCGAGATTTATGGCTTCCGCCAGATGATCATGGGCAAACTTTAA

Upstream 100 bases:

>100_bases
GATGTCGGTTGTGGTGGCAGCCGCGGCATTGATGCTGACTGCGAGTCCTGCCTTTGCGCTTGGCAGCCTGATGCTGATGG
CTGGGTAAAGGATAGAACTC

Downstream 100 bases:

>100_bases
GGGCGACGGAGATGTTTCATGCCAGCAAGAATTAGCCGCGCCACCTATGCGCAAATGTTCGGCCCCACCGTTGGCGACAA
GGTGCGCCTTGCCGATACGG

Product: urease subunit beta

Products: NA

Alternate protein names: Urea amidohydrolase subunit beta 1

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MIPGEIITLEGDIELNQGQPTVTMRVANTGDRPIQVGSHFHFYEVNAALSFDREKARGQRLDIAAGTAVRFEPGQERDVT
LVPIRGHREIYGFRQMIMGKL

Sequences:

>Translated_101_residues
MIPGEIITLEGDIELNQGQPTVTMRVANTGDRPIQVGSHFHFYEVNAALSFDREKARGQRLDIAAGTAVRFEPGQERDVT
LVPIRGHREIYGFRQMIMGKL
>Mature_101_residues
MIPGEIITLEGDIELNQGQPTVTMRVANTGDRPIQVGSHFHFYEVNAALSFDREKARGQRLDIAAGTAVRFEPGQERDVT
LVPIRGHREIYGFRQMIMGKL

Specific function: Disruption of the ure1 gene cluster suggests that it protects brucellae during their passage through the stomach. The major route of infection in human brucellosis is oral

COG id: COG0832

COG function: function code E; Urea amidohydrolase (urease) beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urease beta subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE21_BRUA2 (Q2YPD6)

Other databases:

- EMBL:   AF361941
- EMBL:   AM040264
- RefSeq:   YP_413770.1
- ProteinModelPortal:   Q2YPD6
- SMR:   Q2YPD6
- STRING:   Q2YPD6
- GeneID:   3789047
- GenomeReviews:   AM040264_GR
- KEGG:   bmf:BAB1_0299
- eggNOG:   COG0832
- HOGENOM:   HBG365918
- OMA:   TLEVSNT
- ProtClustDB:   PRK13203
- BioCyc:   BMEL359391:BAB1_0299-MONOMER
- GO:   GO:0005737
- GO:   GO:0009405
- HAMAP:   MF_01954
- InterPro:   IPR002019
- Gene3D:   G3DSA:2.10.150.10
- TIGRFAMs:   TIGR00192

Pfam domain/function: PF00699 Urease_beta; SSF51278 Urease_beta

EC number: =3.5.1.5

Molecular weight: Translated: 11337; Mature: 11337

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPGEIITLEGDIELNQGQPTVTMRVANTGDRPIQVGSHFHFYEVNAALSFDREKARGQR
CCCCEEEEEECCEEECCCCCEEEEEEECCCCCEEEECCEEEEEEEEEEEEECCHHCCCCE
LDIAAGTAVRFEPGQERDVTLVPIRGHREIYGFRQMIMGKL
EEEECCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIPGEIITLEGDIELNQGQPTVTMRVANTGDRPIQVGSHFHFYEVNAALSFDREKARGQR
CCCCEEEEEECCEEECCCCCEEEEEEECCCCCEEEECCEEEEEEEEEEEEECCHHCCCCE
LDIAAGTAVRFEPGQERDVTLVPIRGHREIYGFRQMIMGKL
EEEECCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA