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The map label for this gene is ureA

Identifier: 225851817

GI number: 225851817

Start: 296056

End: 296358

Strand: Direct

Name: ureA

Synonym: BMEA_A0301

Alternate gene names: 225851817

Gene position: 296056-296358 (Clockwise)

Preceding gene: 225851816

Following gene: 225851818

Centisome position: 13.93

GC content: 60.4

Gene sequence:

>303_bases
ATGAATTTGACGCCCAGGGAAAAAGACAAACTTTTGATCGCGATGGCCGCCATGGTTGCCCGCCGCCGTCTGGAACGTGG
GGTGAAGCTCAACCATCCCGAAGCCATCGCCCTCGTCAGCGATTTTGTGGTTGAAGGCGCGCGCGACGGGCGCACCGTGG
CCGAACTGATGGAAGCCGGTGCGCATGTCATCACCCGCGAACAGGTGATGGACGGCGTGGCCGAAATGATCCGCGACATT
CAGGTCGAGGCCACTTTTCCCGATGGCACGAAGCTCGTCACGGTGCACGAGCCCATCCGATAA

Upstream 100 bases:

>100_bases
TGGTTAAGCCCGTGCGGCAATTACGCATTTTCAAGGCGTGGATAGCATTCGCATCTCATCGCCTTGGTATTAACTGAAAC
AGCTCCAAGGAAGCGAAGTC

Downstream 100 bases:

>100_bases
GAGATTGCCCATTCTCAGGCGCTGCTTGTGCAGGCCTGTTTTTTTGAAAGGTATGAAAATGAAGAAGATGTCGGTTGTGG
TGGCAGCCGCGGCATTGATG

Product: urease subunit gamma

Products: NA

Alternate protein names: Urea amidohydrolase subunit gamma 1

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MNLTPREKDKLLIAMAAMVARRRLERGVKLNHPEAIALVSDFVVEGARDGRTVAELMEAGAHVITREQVMDGVAEMIRDI
QVEATFPDGTKLVTVHEPIR

Sequences:

>Translated_100_residues
MNLTPREKDKLLIAMAAMVARRRLERGVKLNHPEAIALVSDFVVEGARDGRTVAELMEAGAHVITREQVMDGVAEMIRDI
QVEATFPDGTKLVTVHEPIR
>Mature_100_residues
MNLTPREKDKLLIAMAAMVARRRLERGVKLNHPEAIALVSDFVVEGARDGRTVAELMEAGAHVITREQVMDGVAEMIRDI
QVEATFPDGTKLVTVHEPIR

Specific function: Disruption of the ure1 gene cluster suggests that it protects brucellae during their passage through the stomach. The major route of infection in human brucellosis is oral

COG id: COG0831

COG function: function code E; Urea amidohydrolase (urease) gamma subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urease gamma subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE31_BRUA2 (Q2YPD7)

Other databases:

- EMBL:   AF361941
- EMBL:   AM040264
- RefSeq:   YP_413769.1
- ProteinModelPortal:   Q2YPD7
- SMR:   Q2YPD7
- STRING:   Q2YPD7
- GeneID:   3789045
- GenomeReviews:   AM040264_GR
- KEGG:   bmf:BAB1_0298
- eggNOG:   COG0831
- HOGENOM:   HBG286300
- OMA:   HERDKLL
- ProtClustDB:   PRK13241
- BioCyc:   BMEL359391:BAB1_0298-MONOMER
- GO:   GO:0005737
- GO:   GO:0009405
- HAMAP:   MF_00739
- InterPro:   IPR002026
- InterPro:   IPR012010
- Gene3D:   G3DSA:3.30.280.10
- PIRSF:   PIRSF001223
- ProDom:   PD002319
- TIGRFAMs:   TIGR00193

Pfam domain/function: PF00547 Urease_gamma; SSF54111 Urease_gamma_reg

EC number: =3.5.1.5

Molecular weight: Translated: 11103; Mature: 11103

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTPREKDKLLIAMAAMVARRRLERGVKLNHPEAIALVSDFVVEGARDGRTVAELMEAG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
AHVITREQVMDGVAEMIRDIQVEATFPDGTKLVTVHEPIR
CHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCC
>Mature Secondary Structure
MNLTPREKDKLLIAMAAMVARRRLERGVKLNHPEAIALVSDFVVEGARDGRTVAELMEAG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCC
AHVITREQVMDGVAEMIRDIQVEATFPDGTKLVTVHEPIR
CHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA