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The map label for this gene is hpaH [H]

Identifier: 225686901

GI number: 225686901

Start: 1136060

End: 1136863

Strand: Reverse

Name: hpaH [H]

Synonym: BMEA_B1152

Alternate gene names: 225686901

Gene position: 1136863-1136060 (Counterclockwise)

Preceding gene: 225686902

Following gene: 225686900

Centisome position: 95.9

GC content: 59.2

Gene sequence:

>804_bases
ATGCTGACGAAGGACGAAATTGAAGCTGCCGCCGCTGCATTGGATGGAGCGGAGAAGACCCGCAGGCAGGTCGGTCTGCT
CTCGCTCAAGCATCCGGGCATGACCATGGATGACGCCTATTCGGTGCAGGCCGCATGGGTGAAGCAGAAAATCGCGGCTG
GCCGCCGGGTGATCGGCTGGAAGATCGGCCTTACATCCAAGGCCATGCAATATGCGCTGAATATCGACATTCCTGATTCC
GGCGTGTTGCTCGATGACATGGCTTTTGAAGATGGCGCGGTCATTCCTGCCGACCGCTTCATCCAGCCGCGCATCGAGGC
GGAAATCGCCTTTACCATGAAGGCGCCGCTGAAAGGGCCGAACGTCTCGGTTTTCGATGTGTTGAACGCCACCGACTATA
TTACGCCTGCGCTGGAAATTCTCGATACGCGCATTTTGCGCGTGGACCCTGAAACGAAAAAAACGCGCAGCATCGTGGAC
ACCATTTCCGATAATGCGGCCAATGCCGGTATCGTGATTGGCGGGCGGCAGATGCGGGCCGATCCGGTGGATATGCGCTG
GATGGGCGCCATCGTCTCGCGCAATGCGCAAGTGGAGGAAACGGGGCTGGGAGCCGGAGTTCTCAACCATCCCGCGCGCG
GCATTGTGTGGCTTGCCAACCGGCTGGCCCTTTATGGCGAGGGTATCGAAGCCGGGCAGATCGTGCTGGCCGGGTCGTTC
ATCTGTCTGGTGGAAGCGCGCCATGGCGACACGATCAACGCGGATTTCGGGCCTTACGGCACCATTGCGTGTCATTTTCT
GTAG

Upstream 100 bases:

>100_bases
CGACCCGCCAATCTGGCTGAAACCCGGCGATGTGGTGGAAGTGGAGGCGGAGGGCATCGGCCTCTTGCGCAACACCATTG
CCGATGAAAAGGTTTAATCC

Downstream 100 bases:

>100_bases
AGTGGTTCCGGTTAAAACGGAATCGCTGGAACCGCTCTAAGTGATTGTTTTGTCGCATTATCCTACGCAAAACGGCTTCG
CACTTTTGCTGGAAATGGTC

Product: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLTKDEIEAAAAALDGAEKTRRQVGLLSLKHPGMTMDDAYSVQAAWVKQKIAAGRRVIGWKIGLTSKAMQYALNIDIPDS
GVLLDDMAFEDGAVIPADRFIQPRIEAEIAFTMKAPLKGPNVSVFDVLNATDYITPALEILDTRILRVDPETKKTRSIVD
TISDNAANAGIVIGGRQMRADPVDMRWMGAIVSRNAQVEETGLGAGVLNHPARGIVWLANRLALYGEGIEAGQIVLAGSF
ICLVEARHGDTINADFGPYGTIACHFL

Sequences:

>Translated_267_residues
MLTKDEIEAAAAALDGAEKTRRQVGLLSLKHPGMTMDDAYSVQAAWVKQKIAAGRRVIGWKIGLTSKAMQYALNIDIPDS
GVLLDDMAFEDGAVIPADRFIQPRIEAEIAFTMKAPLKGPNVSVFDVLNATDYITPALEILDTRILRVDPETKKTRSIVD
TISDNAANAGIVIGGRQMRADPVDMRWMGAIVSRNAQVEETGLGAGVLNHPARGIVWLANRLALYGEGIEAGQIVLAGSF
ICLVEARHGDTINADFGPYGTIACHFL
>Mature_267_residues
MLTKDEIEAAAAALDGAEKTRRQVGLLSLKHPGMTMDDAYSVQAAWVKQKIAAGRRVIGWKIGLTSKAMQYALNIDIPDS
GVLLDDMAFEDGAVIPADRFIQPRIEAEIAFTMKAPLKGPNVSVFDVLNATDYITPALEILDTRILRVDPETKKTRSIVD
TISDNAANAGIVIGGRQMRADPVDMRWMGAIVSRNAQVEETGLGAGVLNHPARGIVWLANRLALYGEGIEAGQIVLAGSF
ICLVEARHGDTINADFGPYGTIACHFL

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=228, Percent_Identity=35.9649122807018, Blast_Score=151, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 28770; Mature: 28770

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKDEIEAAAAALDGAEKTRRQVGLLSLKHPGMTMDDAYSVQAAWVKQKIAAGRRVIGW
CCCHHHHHHHHHHHCCHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
KIGLTSKAMQYALNIDIPDSGVLLDDMAFEDGAVIPADRFIQPRIEAEIAFTMKAPLKGP
EECCCHHHEEEEEEECCCCCCEEEECCCCCCCCCCCHHHCCCCCCCEEEEEEEECCCCCC
NVSVFDVLNATDYITPALEILDTRILRVDPETKKTRSIVDTISDNAANAGIVIGGRQMRA
CEEEEEECCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCCC
DPVDMRWMGAIVSRNAQVEETGLGAGVLNHPARGIVWLANRLALYGEGIEAGQIVLAGSF
CCCCHHHHHHHHHCCCEEHHCCCCCCHHCCCCCHHHHHHHHHHEECCCCCCCEEEEECCE
ICLVEARHGDTINADFGPYGTIACHFL
EEEEEECCCCEECCCCCCCCCEEEEEC
>Mature Secondary Structure
MLTKDEIEAAAAALDGAEKTRRQVGLLSLKHPGMTMDDAYSVQAAWVKQKIAAGRRVIGW
CCCHHHHHHHHHHHCCHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
KIGLTSKAMQYALNIDIPDSGVLLDDMAFEDGAVIPADRFIQPRIEAEIAFTMKAPLKGP
EECCCHHHEEEEEEECCCCCCEEEECCCCCCCCCCCHHHCCCCCCCEEEEEEEECCCCCC
NVSVFDVLNATDYITPALEILDTRILRVDPETKKTRSIVDTISDNAANAGIVIGGRQMRA
CEEEEEECCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCCC
DPVDMRWMGAIVSRNAQVEETGLGAGVLNHPARGIVWLANRLALYGEGIEAGQIVLAGSF
CCCCHHHHHHHHHCCCEEHHCCCCCCHHCCCCCHHHHHHHHHHEECCCCCCCEEEEECCE
ICLVEARHGDTINADFGPYGTIACHFL
EEEEEECCCCEECCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]