| Definition | Brucella melitensis ATCC 23457 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_012442 |
| Length | 1,185,518 |
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The map label for this gene is iolC [H]
Identifier: 225686486
GI number: 225686486
Start: 671621
End: 673525
Strand: Direct
Name: iolC [H]
Synonym: BMEA_B0688
Alternate gene names: 225686486
Gene position: 671621-673525 (Clockwise)
Preceding gene: 225686485
Following gene: 225686487
Centisome position: 56.65
GC content: 60.52
Gene sequence:
>1905_bases ATGTCGAAGCGGCTGGACCTGATAACGATTGGTCGATCTTCGGTGGATCTCTACGGCGCGCAGATTGGCGGCCTTCTCGA AGACATGGCTTCGTTCAACAAATATGTCGGCGGCTCCCCCACCAATATCGCAACCGGAACGGCACGGCTAGGCCTCAGAT CGGCGCTCATCACCCGGGTCGGCGATGAGCATATGGGGCGCTTCCTGCTGCGTGAACTGGAACGCGAAGGCGTCGACACA CGCGGCATCGTCACCGATCCTGAACGGCTGACGGCACTTGTTATTCTGGGCATTCGCGATCAGCAACATTTCCCGCTCAT CTTCTATCGCGAGAACTGCGCCGACATGGCGCTTTGCGAAGACGATATCGACCCGGATTTCATCGCGGAAGCCCGTTGTG TGCTTGCCACGGGCACGCATCTGTCGCATCCGCGTACGGAAGCCGCCGTTTTGAAGGCGCTGCGCCTTGCGCGCGAAAAC GGCAGCCGCACGGCGCTTGATATTGATTATCGCCCCAACCTATGGGGGCTTTCCGGCCACGGCGACGGCGAAAACCGCTT TATTGAAAGCGCGGCCGTCACCGCCAAGCTGCAATCGACGCTCCACCTCTTCGACCTGATCGTCGGCACGGAAGAAGAAT TCCATATAGCAGGCGGCTCGACCGATACGCTGGAAGCGCTCAAGGCCGTGCGCAGGGTCACGAAAGCAGCACTGGTGTGC AAGCGCGGACCGATGGGCGCAGTGGTTTTCGAGGGCGATATTCCCGACGACCTGGACAAAGGGCAGAGCGGTCAGGGCTT TCCGATCGAGGTGTTCAACGTTCTGGGCGCGGGCGATGGTTTCATGTCCGGCCTGCTTCGCGGCTGGCTCAAGGGTGAAG ACTGGCCGACCAGCCTGAAATTTGCCAATGCCTGCGGCGCTTTTGCGGTGTCGCGCCATGGCTGCACCCCTGCCTATCCA AGCTGGGAGGAACTGCAATTTTTCCTGCAACGCGGTATTCGCAACAAGGCGCTGCGCAAGGATGCAGAACTGGAACAGGT ACACTGGTCCACCAACCGCAATGGCACATGGCCGCATATGCGCGTTTTTGCCTTTGATCATCGCATCCAGCTTGAGGAAA TGGCGGCGGAAGCCGGTGTCTCGACGGACAAGATCGGTGAATTCAAGCAGCTTTGCCTTGATGCGGCCCTGAAAGTTGCA GGCGGCGCGCAAGGCTATGGTATTTTGTGCGACGGGCGGCTCGGCCGCGACGCCCTCTACCGGGCGGCGGGTACGGGCCT TTGGATCGGACGCCCCGCCGAATGGCCGGGCTCGCGCCCGTTGAAGCTTGAACCCGAACTCGGCCCCGATTGCGGCGGCC TGATGGAATGGCCGGTGGAACATGTGGTGAAACTTCTGTGTTTCTACCACCCGGACGATCCGGCGGAAATGCGCGCCGGG CAGGAAGAGACGGTTCAACGTCTTTTCACAGCCGCACGGCGTAACCGTCTGGAATTCCTTCTGGAAATCATCCCGTCCAA AGCCGGCCCGGTGGACGACATGACGACCGCCCGCGTGATCGAACGCTTCTATGAGATCGGCGTCTATCCCGACTGGTGGA AGCTGGAGCCATTGAAGACAAAGGCCGCATGGGCCAATGCCTGCGATGCCATCACCCGCAACGACCCGCACACACGCGGC ATTGTGGTGCTGGGCCTTGATGCTCCGGCGGAGGAACTTGAGCAAAGCCTTGGGATTGCGGCGGGCTTTGATCTTGTGAA AGGTTTTGCCGTAGGCCGTACGATCTTTGCAGAGGCCGCGCGTAAATGGCTGAGCGGCACGATTGACGATGCGCAAGCCA TCGCCGAAATGGCCGCGCGCTACCAGAGCCTTTGCGACGTGTGGGACAAGGCGCACGCTTACTGA
Upstream 100 bases:
>100_bases GCTGGATAGGATTCCATTTTTCAGTTGAAATGGAATATTAAATCCATTTTAATTGGAAATGGAATAACTGCTATGCACGC AGCAGCGACGAGGAGGCACG
Downstream 100 bases:
>100_bases ACACTTTCCCTCGGGGGAAGGATGGAGGAAATATGAAAACCGTTCGACTGACCGCCGCGCAGGCACTGGTGCGCTATCTG GCCAACCAGATGACGCCGGA
Product: Fructokinase-1
Products: NA
Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]
Number of amino acids: Translated: 634; Mature: 633
Protein sequence:
>634_residues MSKRLDLITIGRSSVDLYGAQIGGLLEDMASFNKYVGGSPTNIATGTARLGLRSALITRVGDEHMGRFLLRELEREGVDT RGIVTDPERLTALVILGIRDQQHFPLIFYRENCADMALCEDDIDPDFIAEARCVLATGTHLSHPRTEAAVLKALRLAREN GSRTALDIDYRPNLWGLSGHGDGENRFIESAAVTAKLQSTLHLFDLIVGTEEEFHIAGGSTDTLEALKAVRRVTKAALVC KRGPMGAVVFEGDIPDDLDKGQSGQGFPIEVFNVLGAGDGFMSGLLRGWLKGEDWPTSLKFANACGAFAVSRHGCTPAYP SWEELQFFLQRGIRNKALRKDAELEQVHWSTNRNGTWPHMRVFAFDHRIQLEEMAAEAGVSTDKIGEFKQLCLDAALKVA GGAQGYGILCDGRLGRDALYRAAGTGLWIGRPAEWPGSRPLKLEPELGPDCGGLMEWPVEHVVKLLCFYHPDDPAEMRAG QEETVQRLFTAARRNRLEFLLEIIPSKAGPVDDMTTARVIERFYEIGVYPDWWKLEPLKTKAAWANACDAITRNDPHTRG IVVLGLDAPAEELEQSLGIAAGFDLVKGFAVGRTIFAEAARKWLSGTIDDAQAIAEMAARYQSLCDVWDKAHAY
Sequences:
>Translated_634_residues MSKRLDLITIGRSSVDLYGAQIGGLLEDMASFNKYVGGSPTNIATGTARLGLRSALITRVGDEHMGRFLLRELEREGVDT RGIVTDPERLTALVILGIRDQQHFPLIFYRENCADMALCEDDIDPDFIAEARCVLATGTHLSHPRTEAAVLKALRLAREN GSRTALDIDYRPNLWGLSGHGDGENRFIESAAVTAKLQSTLHLFDLIVGTEEEFHIAGGSTDTLEALKAVRRVTKAALVC KRGPMGAVVFEGDIPDDLDKGQSGQGFPIEVFNVLGAGDGFMSGLLRGWLKGEDWPTSLKFANACGAFAVSRHGCTPAYP SWEELQFFLQRGIRNKALRKDAELEQVHWSTNRNGTWPHMRVFAFDHRIQLEEMAAEAGVSTDKIGEFKQLCLDAALKVA GGAQGYGILCDGRLGRDALYRAAGTGLWIGRPAEWPGSRPLKLEPELGPDCGGLMEWPVEHVVKLLCFYHPDDPAEMRAG QEETVQRLFTAARRNRLEFLLEIIPSKAGPVDDMTTARVIERFYEIGVYPDWWKLEPLKTKAAWANACDAITRNDPHTRG IVVLGLDAPAEELEQSLGIAAGFDLVKGFAVGRTIFAEAARKWLSGTIDDAQAIAEMAARYQSLCDVWDKAHAY >Mature_633_residues SKRLDLITIGRSSVDLYGAQIGGLLEDMASFNKYVGGSPTNIATGTARLGLRSALITRVGDEHMGRFLLRELEREGVDTR GIVTDPERLTALVILGIRDQQHFPLIFYRENCADMALCEDDIDPDFIAEARCVLATGTHLSHPRTEAAVLKALRLARENG SRTALDIDYRPNLWGLSGHGDGENRFIESAAVTAKLQSTLHLFDLIVGTEEEFHIAGGSTDTLEALKAVRRVTKAALVCK RGPMGAVVFEGDIPDDLDKGQSGQGFPIEVFNVLGAGDGFMSGLLRGWLKGEDWPTSLKFANACGAFAVSRHGCTPAYPS WEELQFFLQRGIRNKALRKDAELEQVHWSTNRNGTWPHMRVFAFDHRIQLEEMAAEAGVSTDKIGEFKQLCLDAALKVAG GAQGYGILCDGRLGRDALYRAAGTGLWIGRPAEWPGSRPLKLEPELGPDCGGLMEWPVEHVVKLLCFYHPDDPAEMRAGQ EETVQRLFTAARRNRLEFLLEIIPSKAGPVDDMTTARVIERFYEIGVYPDWWKLEPLKTKAAWANACDAITRNDPHTRGI VVLGLDAPAEELEQSLGIAAGFDLVKGFAVGRTIFAEAARKWLSGTIDDAQAIAEMAARYQSLCDVWDKAHAY
Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]
COG id: COG0524
COG function: function code G; Sugar kinases, ribokinase family
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the carbohydrate kinase pfkB family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011611 - InterPro: IPR002173 - InterPro: IPR022841 [H]
Pfam domain/function: PF00294 PfkB [H]
EC number: =2.7.1.92 [H]
Molecular weight: Translated: 69736; Mature: 69605
Theoretical pI: Translated: 5.34; Mature: 5.34
Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSKRLDLITIGRSSVDLYGAQIGGLLEDMASFNKYVGGSPTNIATGTARLGLRSALITRV CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC GDEHMGRFLLRELEREGVDTRGIVTDPERLTALVILGIRDQQHFPLIFYRENCADMALCE CHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEEEEECCCCCCCEEEEECCCCCHHHCC DDIDPDFIAEARCVLATGTHLSHPRTEAAVLKALRLARENGSRTALDIDYRPNLWGLSGH CCCCHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCC GDGENRFIESAAVTAKLQSTLHLFDLIVGTEEEFHIAGGSTDTLEALKAVRRVTKAALVC CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH KRGPMGAVVFEGDIPDDLDKGQSGQGFPIEVFNVLGAGDGFMSGLLRGWLKGEDWPTSLK CCCCCEEEEECCCCCCHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHH FANACGAFAVSRHGCTPAYPSWEELQFFLQRGIRNKALRKDAELEQVHWSTNRNGTWPHM HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCEE RVFAFDHRIQLEEMAAEAGVSTDKIGEFKQLCLDAALKVAGGAQGYGILCDGRLGRDALY EEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHH RAAGTGLWIGRPAEWPGSRPLKLEPELGPDCGGLMEWPVEHVVKLLCFYHPDDPAEMRAG HHCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHCC QEETVQRLFTAARRNRLEFLLEIIPSKAGPVDDMTTARVIERFYEIGVYPDWWKLEPLKT HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCH KAAWANACDAITRNDPHTRGIVVLGLDAPAEELEQSLGIAAGFDLVKGFAVGRTIFAEAA HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH RKWLSGTIDDAQAIAEMAARYQSLCDVWDKAHAY HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure SKRLDLITIGRSSVDLYGAQIGGLLEDMASFNKYVGGSPTNIATGTARLGLRSALITRV CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC GDEHMGRFLLRELEREGVDTRGIVTDPERLTALVILGIRDQQHFPLIFYRENCADMALCE CHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEEEEECCCCCCCEEEEECCCCCHHHCC DDIDPDFIAEARCVLATGTHLSHPRTEAAVLKALRLARENGSRTALDIDYRPNLWGLSGH CCCCHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCC GDGENRFIESAAVTAKLQSTLHLFDLIVGTEEEFHIAGGSTDTLEALKAVRRVTKAALVC CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH KRGPMGAVVFEGDIPDDLDKGQSGQGFPIEVFNVLGAGDGFMSGLLRGWLKGEDWPTSLK CCCCCEEEEECCCCCCHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHH FANACGAFAVSRHGCTPAYPSWEELQFFLQRGIRNKALRKDAELEQVHWSTNRNGTWPHM HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCEE RVFAFDHRIQLEEMAAEAGVSTDKIGEFKQLCLDAALKVAGGAQGYGILCDGRLGRDALY EEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHH RAAGTGLWIGRPAEWPGSRPLKLEPELGPDCGGLMEWPVEHVVKLLCFYHPDDPAEMRAG HHCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHCC QEETVQRLFTAARRNRLEFLLEIIPSKAGPVDDMTTARVIERFYEIGVYPDWWKLEPLKT HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCH KAAWANACDAITRNDPHTRGIVVLGLDAPAEELEQSLGIAAGFDLVKGFAVGRTIFAEAA HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH RKWLSGTIDDAQAIAEMAARYQSLCDVWDKAHAY HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA