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The map label for this gene is murR [H]

Identifier: 225686485

GI number: 225686485

Start: 670699

End: 671529

Strand: Direct

Name: murR [H]

Synonym: BMEA_B0687

Alternate gene names: 225686485

Gene position: 670699-671529 (Clockwise)

Preceding gene: 225686482

Following gene: 225686486

Centisome position: 56.57

GC content: 58.72

Gene sequence:

>831_bases
ATGGATTCCACCCCTTCGCCATCTCCGGCCCCGGCGAGCATAAAAGAATTCGAGGCGCGATTGCTGGAGGTTGCCGACCG
CCTGCCCAAGCGCCTGAAGCAATGCGCCGATTATGTCGCCGCCAATCAGGATCGCATCGCGGTTTCCACCGTGGCGGAAA
TGGCCGAAGGTGCGGGCGTGCAAAGTTCTGCTTTCATGCGCTTTTGCCAGATTTTGGGTTTTTCGGGTTTTTCGGAAATG
CAGCGCCTTTTTCGCGAAACCTATGCGGGCGGCTGGCCGGATTATTCCACCCGCCTCCTGCATTTGCGTGAAACAGCGGC
AGGTAGAGCGCCAGCACTTCTGGCCGAATTTGCCGAGGCCGGGCGCACCTCGCTTGAGGGACTTCTGAAAACGATCGAAC
CGGAGGCGCTGGAAAAGGCCGTGGAGCTGCTCGCCAGCGCCAACACGATCCATATCATCGGTATCCGCCGCGCCTTTCCG
GTTGCAAGCTATCTCGCCTATGCGCTGGAAAAAATGGCGGTTCCGGCCATGCTGCACAGTGCAGTCGGCAAACTGGAGAA
CCTCCACGCAATCCGCAAGGGCGATGTGCTTCTGGCCATTACCTTCTCGCCTTACTCGCCGGAAACGATCGGCATGACCG
AGGCTGTTGCCGCGCGGGGCATTGATGTCATCGGCATTACCGACACGATCGTAAGCCCCATGAGCAAGGTCGCCAGACAG
ACACTTCTCGTTTCCGAAGTGGATTTTGGTGCGTTTCGCTCGCTTTCGGCAACACTTTGTCTTGCCATCGCCATTGCTGT
TGCGGTGGGCACTGCCCGTCAGGCTGGATAG

Upstream 100 bases:

>100_bases
CGCTTATTGGGGATGGAATACGATGCATTGTGGAATATTTATTCTATTTTGCTAGAATGCGGCATAATGATTGTCAAGAC
AGGGTTTTGAAAGGATACCG

Downstream 100 bases:

>100_bases
GATTCCATTTTTCAGTTGAAATGGAATATTAAATCCATTTTAATTGGAAATGGAATAACTGCTATGCACGCAGCAGCGAC
GAGGAGGCACGATGTCGAAG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDSTPSPSPAPASIKEFEARLLEVADRLPKRLKQCADYVAANQDRIAVSTVAEMAEGAGVQSSAFMRFCQILGFSGFSEM
QRLFRETYAGGWPDYSTRLLHLRETAAGRAPALLAEFAEAGRTSLEGLLKTIEPEALEKAVELLASANTIHIIGIRRAFP
VASYLAYALEKMAVPAMLHSAVGKLENLHAIRKGDVLLAITFSPYSPETIGMTEAVAARGIDVIGITDTIVSPMSKVARQ
TLLVSEVDFGAFRSLSATLCLAIAIAVAVGTARQAG

Sequences:

>Translated_276_residues
MDSTPSPSPAPASIKEFEARLLEVADRLPKRLKQCADYVAANQDRIAVSTVAEMAEGAGVQSSAFMRFCQILGFSGFSEM
QRLFRETYAGGWPDYSTRLLHLRETAAGRAPALLAEFAEAGRTSLEGLLKTIEPEALEKAVELLASANTIHIIGIRRAFP
VASYLAYALEKMAVPAMLHSAVGKLENLHAIRKGDVLLAITFSPYSPETIGMTEAVAARGIDVIGITDTIVSPMSKVARQ
TLLVSEVDFGAFRSLSATLCLAIAIAVAVGTARQAG
>Mature_276_residues
MDSTPSPSPAPASIKEFEARLLEVADRLPKRLKQCADYVAANQDRIAVSTVAEMAEGAGVQSSAFMRFCQILGFSGFSEM
QRLFRETYAGGWPDYSTRLLHLRETAAGRAPALLAEFAEAGRTSLEGLLKTIEPEALEKAVELLASANTIHIIGIRRAFP
VASYLAYALEKMAVPAMLHSAVGKLENLHAIRKGDVLLAITFSPYSPETIGMTEAVAARGIDVIGITDTIVSPMSKVARQ
TLLVSEVDFGAFRSLSATLCLAIAIAVAVGTARQAG

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 29456; Mature: 29456

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTPSPSPAPASIKEFEARLLEVADRLPKRLKQCADYVAANQDRIAVSTVAEMAEGAGV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
QSSAFMRFCQILGFSGFSEMQRLFRETYAGGWPDYSTRLLHLRETAAGRAPALLAEFAEA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
GRTSLEGLLKTIEPEALEKAVELLASANTIHIIGIRRAFPVASYLAYALEKMAVPAMLHS
CHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
AVGKLENLHAIRKGDVLLAITFSPYSPETIGMTEAVAARGIDVIGITDTIVSPMSKVARQ
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
TLLVSEVDFGAFRSLSATLCLAIAIAVAVGTARQAG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSTPSPSPAPASIKEFEARLLEVADRLPKRLKQCADYVAANQDRIAVSTVAEMAEGAGV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
QSSAFMRFCQILGFSGFSEMQRLFRETYAGGWPDYSTRLLHLRETAAGRAPALLAEFAEA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
GRTSLEGLLKTIEPEALEKAVELLASANTIHIIGIRRAFPVASYLAYALEKMAVPAMLHS
CHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
AVGKLENLHAIRKGDVLLAITFSPYSPETIGMTEAVAARGIDVIGITDTIVSPMSKVARQ
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
TLLVSEVDFGAFRSLSATLCLAIAIAVAVGTARQAG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA