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The map label for this gene is galE [H]

Identifier: 225686334

GI number: 225686334

Start: 503441

End: 504427

Strand: Direct

Name: galE [H]

Synonym: BMEA_B0516

Alternate gene names: 225686334

Gene position: 503441-504427 (Clockwise)

Preceding gene: 225686333

Following gene: 225686335

Centisome position: 42.47

GC content: 61.9

Gene sequence:

>987_bases
ATGTCCGCGAACAACGTCCTCGTCGTCGGTGGCGCCGGATTCATCGGCAGCCACACGGCCAAGCTTCTGGCCGGGCAGGG
CTATGCACCCGTCGTCTACGACAATCTTTCGACGGGCCATCAATCCGCCGTCCGGTGGGGCGACTTTGTCGAGGGCGACA
TTCTTGACCAGGCGCGTCTGGTCGAGACAATGGAAAAATATGCGCCGGTCGCGGTAATCCATTTCGCCGCCTCGGCCTAT
GTCGGGGAATCGGTGGAGGACCCCGCCAAATATTATCGCAACAATGTAGGCGGAACGCAGTCGCTTCTCGACGCCTGCCG
TCTGACGCGCACGCAAAACGTTATCTTCTCCTCCAGTTGCGCCACCTATGGCGTGCCCAGCCGGCTTCCCATCGGGGAGG
GCGAGGCCCAGAATCCGATCAACCCTTATGGGCGCACAAAGTTGATCGCCGAGCACATGCTGGCCGATTATGCGGTGGCC
TACGGGCTGCGTTATGTGGCGCTACGCTATTTCAATGCATCCGGTGCCGATATCGACGGTGAACTGGGCGAAAAGCACGA
CCCTGAAACACATCTCATCCCGCGCGCCATGATGGCCGCCGCTGGCAGGCTCGACGTTCTGGAAGTCTATGGCGACGATT
ACGAGACGCCGGACGGCACCTGCATCCGCGACTATATCCATGTCACCGATCTCGCGCGGGCGCATGTGCTGGCGGTCGAG
CATCTGAAGGAAGCCGGGGGCAATCTGGCCGTTAATCTGGGTACCGGGCGTGGCACGTCAAGTCGTGAGATCGTGCAGTC
CATTGGCCGCCTGACGGGCCGTAGCGTGCCGGTCGCCATGCGCGCGCGCCGTGCCGGCGATCCGCCAGCGCTCTATGCCG
ACCCGGCACTTGCTGCCGAAAAGCTCGGCTTCCATACGGTCTATTCCGATCTGGACACTATCATCCGCACCGCTGCCCCA
CACTTCGGACTGGAGGTTAGGGGATGA

Upstream 100 bases:

>100_bases
GGGAGCCGACCGTGGCGCTGGCCCAGGGCCTGGAACCGACTATCGCCTATTTCGAGCATCAGTTGAGAAAGCCGACCGGC
AAGCTGGTGGAGGCCGCATA

Downstream 100 bases:

>100_bases
AAATGCGTTCCACCGATAGCAGGGCCGATCAGGTTTCGGCATGGGCTCCGGTATTTGGCGGCGTGTCGAATATCTGCTGG
GCGCTGGCGTCTGGGTTGCT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETMEKYAPVAVIHFAASAY
VGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVA
YGLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVE
HLKEAGGNLAVNLGTGRGTSSREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIRTAAP
HFGLEVRG

Sequences:

>Translated_328_residues
MSANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETMEKYAPVAVIHFAASAY
VGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVA
YGLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVE
HLKEAGGNLAVNLGTGRGTSSREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIRTAAP
HFGLEVRG
>Mature_327_residues
SANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETMEKYAPVAVIHFAASAYV
GESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAY
GLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVEH
LKEAGGNLAVNLGTGRGTSSREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIRTAAPH
FGLEVRG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=321, Percent_Identity=43.3021806853583, Blast_Score=238, Evalue=5e-63,
Organism=Homo sapiens, GI56118217, Length=321, Percent_Identity=43.3021806853583, Blast_Score=238, Evalue=5e-63,
Organism=Homo sapiens, GI189083684, Length=321, Percent_Identity=43.3021806853583, Blast_Score=238, Evalue=5e-63,
Organism=Homo sapiens, GI7657641, Length=286, Percent_Identity=25.8741258741259, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI42516563, Length=313, Percent_Identity=26.1980830670927, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786974, Length=312, Percent_Identity=41.6666666666667, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI48994969, Length=294, Percent_Identity=28.2312925170068, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790049, Length=265, Percent_Identity=29.0566037735849, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788365, Length=315, Percent_Identity=25.3968253968254, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=321, Percent_Identity=40.809968847352, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71982038, Length=323, Percent_Identity=40.2476780185758, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17568069, Length=246, Percent_Identity=28.4552845528455, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=348, Percent_Identity=37.6436781609195, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19923002, Length=324, Percent_Identity=38.2716049382716, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21356223, Length=284, Percent_Identity=26.4084507042254, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35162; Mature: 35031

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARL
CCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHCCCCCCHHHHHHHH
VETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSC
HHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCEEEECCC
ATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGLRYVALRYFNASGADIDG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
ELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVE
CCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HLKEAGGNLAVNLGTGRGTSSREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAE
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECHHHHHH
KLGFHTVYSDLDTIIRTAAPHFGLEVRG
HHHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
SANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARL
CCCCEEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHCCCCCCHHHHHHHH
VETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSC
HHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCEEEECCC
ATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGLRYVALRYFNASGADIDG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCC
ELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLAVE
CCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HLKEAGGNLAVNLGTGRGTSSREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAE
HHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECHHHHHH
KLGFHTVYSDLDTIIRTAAPHFGLEVRG
HHHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]