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The map label for this gene is hflK [H]

Identifier: 225630543

GI number: 225630543

Start: 857909

End: 858943

Strand: Direct

Name: hflK [H]

Synonym: WRi_007980

Alternate gene names: 225630543

Gene position: 857909-858943 (Clockwise)

Preceding gene: 225630542

Following gene: 225630544

Centisome position: 59.34

GC content: 34.98

Gene sequence:

>1035_bases
ATGTTTGATGAGAATAATCCTTGGAATTTGGGAAAGAAACCGGTAGGGAACAAAACTCCTAATAATGAAGATATTTTAAG
TAAAGCTGTATCTGATATAGGGTTCTTTCTTAATGGATTAACCAAAAACAGGGGCAAAAAACCTTATTTCATCATTTTCA
TTATTTTGCTACTCTATGCTTGTACAGGCTTTTACATTGTTCACCCAAGTGAAGAAGGCATAGAACTTACCTTTGGTAAA
TACTCTAACACAGAAATGTCCGGTTTGCGTTATCACTTCCCCTACCCTATTGGCAAGGTTTTTAAAGTGAACGTTAAGGA
AGTAAATCGTGAAGAAATTGGGGTAAGTAGTTCTTATGGGCGAGATACAGATCGCGGTGAAGGCGTGATGCTAACTGGAG
ATGAAAATATAGTCAACGTTAACTTCGAGGTTCAATGGCGCGTTAGAGATGCTAAGGACTATTTATTCAAAGTGCGGGAT
TACAAACCCGGTTTCAGTGTTAAAAATGCTGCTGAAAGTGCCATGAGAGAAATAATAGGTAAAAATACGATCTCTTTTGC
ACTTGGTCAAGGCAGACCAGAAATTTCTAGAGATACTAGAATTCTATTGCAGCAGATTCTTGATGGATACCAAATGGGTA
TAGAGATTTTATCTGTTCAAATGAAAAAAATTGATCCACCAGAAAAAGTAATCAGTTCGTTTAGAGATGTACAAAGTGCT
CGTGCAGACAAAGAGCGTACTATAAACGAAGCATATGCTTATAATAATGATATTATACCTCGAGCAAAGGGTGAAGCGAT
AAAGATAAAATTAGATGCACAAGCATATGAAAATGAAGTAATAAATGAAGCAAAAGGTAATGCAAATCGCTTTTTATCTC
TTTATGAGGAATATAGACAGAATCCTTCTCTCGTTAAGAATCGTATTTATCTTGAAACTATGGAAAATATTTTCAGTAAG
GTAGACAAAGTTGTTGTAACTGATGATCTGAAAGGTATGTTTTCTTATTTACCTCTTACAAATTTAGGAAAATAA

Upstream 100 bases:

>100_bases
ATCATGTCCTTCGCTCTGATAATTAATTTGTAAATAAAATAGTTTTGCATTTTCTTATAAGATGAGTAATATTAGCGTAT
TAATTATAGAATCAATCATT

Downstream 100 bases:

>100_bases
CCATGAGTAGTAATATTAAAATTGTTTTTGTTTCTGTATTTGTTGTTTTATTGATTGTTTTATCTAATTCAATATTTGTT
GTGCAAGAAACAAAGCAAGC

Product: hflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MFDENNPWNLGKKPVGNKTPNNEDILSKAVSDIGFFLNGLTKNRGKKPYFIIFIILLLYACTGFYIVHPSEEGIELTFGK
YSNTEMSGLRYHFPYPIGKVFKVNVKEVNREEIGVSSSYGRDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRD
YKPGFSVKNAAESAMREIIGKNTISFALGQGRPEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSA
RADKERTINEAYAYNNDIIPRAKGEAIKIKLDAQAYENEVINEAKGNANRFLSLYEEYRQNPSLVKNRIYLETMENIFSK
VDKVVVTDDLKGMFSYLPLTNLGK

Sequences:

>Translated_344_residues
MFDENNPWNLGKKPVGNKTPNNEDILSKAVSDIGFFLNGLTKNRGKKPYFIIFIILLLYACTGFYIVHPSEEGIELTFGK
YSNTEMSGLRYHFPYPIGKVFKVNVKEVNREEIGVSSSYGRDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRD
YKPGFSVKNAAESAMREIIGKNTISFALGQGRPEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSA
RADKERTINEAYAYNNDIIPRAKGEAIKIKLDAQAYENEVINEAKGNANRFLSLYEEYRQNPSLVKNRIYLETMENIFSK
VDKVVVTDDLKGMFSYLPLTNLGK
>Mature_344_residues
MFDENNPWNLGKKPVGNKTPNNEDILSKAVSDIGFFLNGLTKNRGKKPYFIIFIILLLYACTGFYIVHPSEEGIELTFGK
YSNTEMSGLRYHFPYPIGKVFKVNVKEVNREEIGVSSSYGRDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRD
YKPGFSVKNAAESAMREIIGKNTISFALGQGRPEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSA
RADKERTINEAYAYNNDIIPRAKGEAIKIKLDAQAYENEVINEAKGNANRFLSLYEEYRQNPSLVKNRIYLETMENIFSK
VDKVVVTDDLKGMFSYLPLTNLGK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=281, Percent_Identity=38.0782918149466, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 39225; Mature: 39225

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDENNPWNLGKKPVGNKTPNNEDILSKAVSDIGFFLNGLTKNRGKKPYFIIFIILLLYA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CTGFYIVHPSEEGIELTFGKYSNTEMSGLRYHFPYPIGKVFKVNVKEVNREEIGVSSSYG
HCCEEEECCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEEHHHCCHHHCCCCCCCC
RDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPGFSVKNAAESAMREIIG
CCCCCCCEEEEECCCCEEEEEEEEEEEEECCHHHHEEHCCCCCCCCHHHHHHHHHHHHHC
KNTISFALGQGRPEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSA
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RADKERTINEAYAYNNDIIPRAKGEAIKIKLDAQAYENEVINEAKGNANRFLSLYEEYRQ
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCC
NPSLVKNRIYLETMENIFSKVDKVVVTDDLKGMFSYLPLTNLGK
CHHHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFDENNPWNLGKKPVGNKTPNNEDILSKAVSDIGFFLNGLTKNRGKKPYFIIFIILLLYA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CTGFYIVHPSEEGIELTFGKYSNTEMSGLRYHFPYPIGKVFKVNVKEVNREEIGVSSSYG
HCCEEEECCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEEHHHCCHHHCCCCCCCC
RDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPGFSVKNAAESAMREIIG
CCCCCCCEEEEECCCCEEEEEEEEEEEEECCHHHHEEHCCCCCCCCHHHHHHHHHHHHHC
KNTISFALGQGRPEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSA
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RADKERTINEAYAYNNDIIPRAKGEAIKIKLDAQAYENEVINEAKGNANRFLSLYEEYRQ
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCC
NPSLVKNRIYLETMENIFSKVDKVVVTDDLKGMFSYLPLTNLGK
CHHHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]