Click here to switch to the map view.

The map label for this gene is ywlC [H]

Identifier: 225630533

GI number: 225630533

Start: 846497

End: 847084

Strand: Reverse

Name: ywlC [H]

Synonym: WRi_007860

Alternate gene names: 225630533

Gene position: 847084-846497 (Counterclockwise)

Preceding gene: 225630534

Following gene: 225630532

Centisome position: 58.59

GC content: 29.76

Gene sequence:

>588_bases
ATGGTATCTAAAATAATAAATGCAATACAGAACAATTTATTAGTGTGTTTTCCAACAGAAACAGTGTATGCTCTTGCTTG
TAATGCACTAGATAATGAATCTATAGGAAAAATATATCAGATAAAGAAACGCTCTCAAAATAAACCACTGTCTATATTTG
TTAGTGATATTTACAATTTGACAAAAATAGCAAAGGTAAAGGAAAGATATATTGATTTAATAAACCACTTTTCTCCTGGA
CCAATTACCTATATTTTACCACTTAAAAACAACAACATATTGCCAAACGAATTCTTTAAAGATAGTATAGGTATCAGAAT
TCCTGAGCATCCTATTGCAATTTCAATACTAAACAAACTGAAAGTTCCAATAGTTGCAACTAGTACAAATATTTCAGGAA
AAGAAAGTGTATGTAAGGCAAACGATATACCACAATCCATTAAGCAACATTTATCTGTAGTGATTGAAGATGACGAACTA
GTTTCTGGTATAGAATCTACTATTATTGACTTAACCGAAGATAAGATTAAGGTTTTAAGGGAAGGTGCAATTTCATTACA
AACAGTAAACAACGCATTTTCAAACTAA

Upstream 100 bases:

>100_bases
GGTAAGCTGCGTTGCATTACGTTTACAAAAACTAGCAGTTACTATATAAGATACAGTGCAACAAAACTGATCTAGTTGTT
ATGAATAAGTTTTTAGCTAT

Downstream 100 bases:

>100_bases
AATCTATAGGAGAAAGAATGAAAAAAGTAATAGGCCACAACCAAGCCAAAAAAAAAATAATGAACAACTTATCTGTTCAG
TCTTGGCTGATCTGTGGTAA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MVSKIINAIQNNLLVCFPTETVYALACNALDNESIGKIYQIKKRSQNKPLSIFVSDIYNLTKIAKVKERYIDLINHFSPG
PITYILPLKNNNILPNEFFKDSIGIRIPEHPIAISILNKLKVPIVATSTNISGKESVCKANDIPQSIKQHLSVVIEDDEL
VSGIESTIIDLTEDKIKVLREGAISLQTVNNAFSN

Sequences:

>Translated_195_residues
MVSKIINAIQNNLLVCFPTETVYALACNALDNESIGKIYQIKKRSQNKPLSIFVSDIYNLTKIAKVKERYIDLINHFSPG
PITYILPLKNNNILPNEFFKDSIGIRIPEHPIAISILNKLKVPIVATSTNISGKESVCKANDIPQSIKQHLSVVIEDDEL
VSGIESTIIDLTEDKIKVLREGAISLQTVNNAFSN
>Mature_195_residues
MVSKIINAIQNNLLVCFPTETVYALACNALDNESIGKIYQIKKRSQNKPLSIFVSDIYNLTKIAKVKERYIDLINHFSPG
PITYILPLKNNNILPNEFFKDSIGIRIPEHPIAISILNKLKVPIVATSTNISGKESVCKANDIPQSIKQHLSVVIEDDEL
VSGIESTIIDLTEDKIKVLREGAISLQTVNNAFSN

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI87081864, Length=186, Percent_Identity=25.2688172043011, Blast_Score=77, Evalue=5e-16,
Organism=Escherichia coli, GI2367210, Length=142, Percent_Identity=24.6478873239437, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=183, Percent_Identity=28.9617486338798, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=192, Percent_Identity=28.6458333333333, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78707274, Length=178, Percent_Identity=29.2134831460674, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 21673; Mature: 21673

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKIINAIQNNLLVCFPTETVYALACNALDNESIGKIYQIKKRSQNKPLSIFVSDIYNL
CHHHHHHHHHCCEEEEEECCCEEHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHH
TKIAKVKERYIDLINHFSPGPITYILPLKNNNILPNEFFKDSIGIRIPEHPIAISILNKL
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHC
KVPIVATSTNISGKESVCKANDIPQSIKQHLSVVIEDDELVSGIESTIIDLTEDKIKVLR
CCCEEEECCCCCCCHHHHCCCCCHHHHHHHHEEEECCHHHHHHHHHHHHHCCHHHHHHHH
EGAISLQTVNNAFSN
HCCHHEEEHHHHHCC
>Mature Secondary Structure
MVSKIINAIQNNLLVCFPTETVYALACNALDNESIGKIYQIKKRSQNKPLSIFVSDIYNL
CHHHHHHHHHCCEEEEEECCCEEHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHH
TKIAKVKERYIDLINHFSPGPITYILPLKNNNILPNEFFKDSIGIRIPEHPIAISILNKL
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHC
KVPIVATSTNISGKESVCKANDIPQSIKQHLSVVIEDDELVSGIESTIIDLTEDKIKVLR
CCCEEEECCCCCCCHHHHCCCCCHHHHHHHHEEEECCHHHHHHHHHHHHHCCHHHHHHHH
EGAISLQTVNNAFSN
HCCHHEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]