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The map label for this gene is atpA [H]

Identifier: 225630274

GI number: 225630274

Start: 537259

End: 538800

Strand: Reverse

Name: atpA [H]

Synonym: WRi_004920

Alternate gene names: 225630274

Gene position: 538800-537259 (Counterclockwise)

Preceding gene: 225630275

Following gene: 225630273

Centisome position: 37.26

GC content: 35.93

Gene sequence:

>1542_bases
ATGAAGAACAGTATGAATGTTTCTGAGATAGCAAGTATAATAAGAGAAAAGGTTGAGACGTTTGATAATCCTATAAAGCG
GGAAAATATAGGTGAAGTAATTTCAGTAACAGATGGTATCGCATTGGTTTATGGGCTGGAAAAAGCAAAATTCGGTGAAA
AGGTATTTTTTGCAAGTGGTGTAGAAGGAATAGTTCTCGATTTAGATCATGATACGGCTGGAATAGTTGTGCTTGGTAAT
GACCGTGATGTGAAAGAAGGGGACGTTGTAAAATGTAGTGGTGATGTTGTGCAGGTGCCTGTAGGACATGAATTGTTAGG
GAGAGTTGTAAATGCGTTGGGCCATCCTATGGACGACGGTGGGGAAATTAGAGCCAAAAACAGAATGGATATAGAATCTA
AAGCGCCAGGCATTATTGATCGTAAGTCTGTGCATGAGCCACTGCAAACAGGAATTAAAATTATAGATTTGCTAATTCCA
ATAGGTAGAGGGCAGCGTGAATTAATTATTGGTGATAGACAAATTGGTAAAACTACTATTGCGCTTGATACTATTATCAA
TCAGAAGAAGATTAACGATGAGGTAAACGAAAATCAAAAAGTTTACTGTGTTTATGTTGCTATTGGGCAAAAAATTTCAA
CAGTAGCAAAAGTGGTAAATAAGCTGAAAGAAAGTGGAGCATTAGAGTATACAACTGTAGTTGTGGCTAGTGCATCTGAC
TGCGCGCCTATGCAATTTTTAGCACCTTATGCTGGTTGTACTATTGGGGAATTTTTCCGTGACAATGGAATGCATTGTTT
GATTATATATGATGATTTATCTAAGCATGCTGTGGCATATAGGCAGATGTCTTTATTGCTCAGACGTCCTCCTGGTCGTG
AAGCTTACCCTGGAGATATATTCTATGTACATTCTCGCTTGCTTGAAAGAGCTGCTAAAATGTCTGATAAAAAAGGGCAG
GGTTCTTTAACTGCTTTGCCAATTGTCGAAACTCAAGCTGGTGATGTATCTGCATATGTGCCAACAAATGTTATTTCAAT
TACCGATGGGCAGATCTTTCTTGAGTCTGAATTATTTTATAAAGGATTTCGACCTGCAGTAAATATAGGTTTGTCAGTTT
CACGGGTTGGTTCTGCTGCACAACTAAAGTCTGTGAAGAAAGTTGCTGGTTCTATAAAGCTAAGCTTAGCTCAGTATAGA
GAATTAGAAGATTTTGCAAAATTTGGTTCTGATCTTGATGCTAGTGTTCAATTATCCTTGAATAAGGGTAAATATCTTGT
CGAGTTATTAAAGCAGAAACAACATTTACCTATGTCAATAGAAGAGCAAGTAGTGCTGATGTATATTTTTTCTAACCTAT
ATAATCAGTTAAGTAAAATACAAATAAGTTACATTAATAAATTTGAACATGATCTTATTAATTATTTTCATACTGTACAC
CCTGGGGTTTTAAAAAAGTTGTCAAATGACATGAGTGATGATATAAAAGGTGATATTTTTAACATTGTGAGTAATTTCGT
TACTCAATTTAATTGCGTTTAG

Upstream 100 bases:

>100_bases
TTAGGTATGGTTTTAATTTGATCGATGCTTCGCTAAAAAGTTACTTGGATAGGTTAGTTGACTTAAGTAAAATGGAAATA
TTAAAAGTAAGGAATTTTGT

Downstream 100 bases:

>100_bases
GTGGTGATTATGGCTTCATCCATTATTAATAAATTTCCTATGACGAGGGAAGGTTTTGAGAATATGCAAGCCGAACTTGA
AAAATTAAAGGAAGAAAAAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKNSMNVSEIASIIREKVETFDNPIKRENIGEVISVTDGIALVYGLEKAKFGEKVFFASGVEGIVLDLDHDTAGIVVLGN
DRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGHPMDDGGEIRAKNRMDIESKAPGIIDRKSVHEPLQTGIKIIDLLIP
IGRGQRELIIGDRQIGKTTIALDTIINQKKINDEVNENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
CAPMQFLAPYAGCTIGEFFRDNGMHCLIIYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDKKGQ
GSLTALPIVETQAGDVSAYVPTNVISITDGQIFLESELFYKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYR
ELEDFAKFGSDLDASVQLSLNKGKYLVELLKQKQHLPMSIEEQVVLMYIFSNLYNQLSKIQISYINKFEHDLINYFHTVH
PGVLKKLSNDMSDDIKGDIFNIVSNFVTQFNCV

Sequences:

>Translated_513_residues
MKNSMNVSEIASIIREKVETFDNPIKRENIGEVISVTDGIALVYGLEKAKFGEKVFFASGVEGIVLDLDHDTAGIVVLGN
DRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGHPMDDGGEIRAKNRMDIESKAPGIIDRKSVHEPLQTGIKIIDLLIP
IGRGQRELIIGDRQIGKTTIALDTIINQKKINDEVNENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
CAPMQFLAPYAGCTIGEFFRDNGMHCLIIYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDKKGQ
GSLTALPIVETQAGDVSAYVPTNVISITDGQIFLESELFYKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYR
ELEDFAKFGSDLDASVQLSLNKGKYLVELLKQKQHLPMSIEEQVVLMYIFSNLYNQLSKIQISYINKFEHDLINYFHTVH
PGVLKKLSNDMSDDIKGDIFNIVSNFVTQFNCV
>Mature_513_residues
MKNSMNVSEIASIIREKVETFDNPIKRENIGEVISVTDGIALVYGLEKAKFGEKVFFASGVEGIVLDLDHDTAGIVVLGN
DRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGHPMDDGGEIRAKNRMDIESKAPGIIDRKSVHEPLQTGIKIIDLLIP
IGRGQRELIIGDRQIGKTTIALDTIINQKKINDEVNENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
CAPMQFLAPYAGCTIGEFFRDNGMHCLIIYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDKKGQ
GSLTALPIVETQAGDVSAYVPTNVISITDGQIFLESELFYKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYR
ELEDFAKFGSDLDASVQLSLNKGKYLVELLKQKQHLPMSIEEQVVLMYIFSNLYNQLSKIQISYINKFEHDLINYFHTVH
PGVLKKLSNDMSDDIKGDIFNIVSNFVTQFNCV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=508, Percent_Identity=59.8425196850394, Blast_Score=627, Evalue=1e-180,
Organism=Homo sapiens, GI4757810, Length=508, Percent_Identity=59.8425196850394, Blast_Score=627, Evalue=1e-180,
Organism=Homo sapiens, GI19913428, Length=294, Percent_Identity=28.9115646258503, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI19913426, Length=295, Percent_Identity=27.4576271186441, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI32189394, Length=375, Percent_Identity=26.1333333333333, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913424, Length=255, Percent_Identity=27.0588235294118, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790172, Length=515, Percent_Identity=51.2621359223301, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1790170, Length=386, Percent_Identity=26.1658031088083, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788251, Length=358, Percent_Identity=27.6536312849162, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=505, Percent_Identity=59.6039603960396, Blast_Score=622, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI71988080, Length=505, Percent_Identity=59.6039603960396, Blast_Score=621, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI71988074, Length=505, Percent_Identity=55.6435643564356, Blast_Score=564, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17570191, Length=323, Percent_Identity=26.9349845201238, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17510931, Length=455, Percent_Identity=25.0549450549451, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25144756, Length=356, Percent_Identity=25.2808988764045, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=68, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=258, Percent_Identity=23.2558139534884, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=42.6666666666667, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=57.029702970297, Blast_Score=605, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319603, Length=388, Percent_Identity=28.3505154639175, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322581, Length=403, Percent_Identity=25.5583126550869, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24658560, Length=511, Percent_Identity=58.7084148727984, Blast_Score=621, Evalue=1e-178,
Organism=Drosophila melanogaster, GI281361666, Length=300, Percent_Identity=28.3333333333333, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24646341, Length=300, Percent_Identity=28.3333333333333, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI17136796, Length=300, Percent_Identity=28.3333333333333, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24638766, Length=375, Percent_Identity=24.5333333333333, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28574560, Length=367, Percent_Identity=26.158038147139, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24583988, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583986, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583984, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583992, Length=257, Percent_Identity=26.4591439688716, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129479, Length=255, Percent_Identity=28.2352941176471, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 56601; Mature: 56601

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSMNVSEIASIIREKVETFDNPIKRENIGEVISVTDGIALVYGLEKAKFGEKVFFASG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEECHHHHCCCEEEEECC
VEGIVLDLDHDTAGIVVLGNDRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGHPMDDG
CCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHCCCCCCC
GEIRAKNRMDIESKAPGIIDRKSVHEPLQTGIKIIDLLIPIGRGQRELIIGDRQIGKTTI
CCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEE
ALDTIINQKKINDEVNENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
HHHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
CAPMQFLAPYAGCTIGEFFRDNGMHCLIIYDDLSKHAVAYRQMSLLLRRPPGREAYPGDI
CCCHHHHHHHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
FYVHSRLLERAAKMSDKKGQGSLTALPIVETQAGDVSAYVPTNVISITDGQIFLESELFY
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHH
KGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYRELEDFAKFGSDLDASVQLSL
CCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
NKGKYLVELLKQKQHLPMSIEEQVVLMYIFSNLYNQLSKIQISYINKFEHDLINYFHTVH
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGVLKKLSNDMSDDIKGDIFNIVSNFVTQFNCV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNSMNVSEIASIIREKVETFDNPIKRENIGEVISVTDGIALVYGLEKAKFGEKVFFASG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEECHHHHCCCEEEEECC
VEGIVLDLDHDTAGIVVLGNDRDVKEGDVVKCSGDVVQVPVGHELLGRVVNALGHPMDDG
CCEEEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHCCCCCCC
GEIRAKNRMDIESKAPGIIDRKSVHEPLQTGIKIIDLLIPIGRGQRELIIGDRQIGKTTI
CCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEE
ALDTIINQKKINDEVNENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASD
HHHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
CAPMQFLAPYAGCTIGEFFRDNGMHCLIIYDDLSKHAVAYRQMSLLLRRPPGREAYPGDI
CCCHHHHHHHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
FYVHSRLLERAAKMSDKKGQGSLTALPIVETQAGDVSAYVPTNVISITDGQIFLESELFY
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHH
KGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYRELEDFAKFGSDLDASVQLSL
CCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
NKGKYLVELLKQKQHLPMSIEEQVVLMYIFSNLYNQLSKIQISYINKFEHDLINYFHTVH
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGVLKKLSNDMSDDIKGDIFNIVSNFVTQFNCV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA