Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 222527027

GI number: 222527027

Start: 4737749

End: 4738768

Strand: Reverse

Name: fabH [H]

Synonym: Chy400_3806

Alternate gene names: 222527027

Gene position: 4738768-4737749 (Counterclockwise)

Preceding gene: 222527028

Following gene: 222527025

Centisome position: 89.94

GC content: 56.57

Gene sequence:

>1020_bases
GTGCTATTCAGGCATGTCATGATCGAAGCAGTCAGTTATGTGTTAGCTCCTCATCGGATCACATCCGATTGGATCGAGGA
TCAGATTGCCGAAACAATGGAGCGTTTACGCTTCCCACGCGGCAAATTAGAGGCGCTATCGGGTATTCGCGAGCGTCGCT
TTTGGGATGAAGGAACGCTGCCCAGCACGGTTGCAACTATGGCGGCTGAGCGTCTCCTCGATCAGGTGGCGATTGATCGC
GAACGCATCGGGCTGCTGATCAATACCTCGGTTTGTCAGGATTACCTCGAACCATCAACCGCGTGCTTCGTGCATCGTAA
TCTTGGCCTTTCGCCGCGAGCAATTAACTACGATGTGCGCAATGCGTGTCTGGGTTTTCTCAACGGCATGGCGATTGCCG
GTATGATGATCGAAGCCGGAACCATCGAATATGCGCTGATCGTTGATGGCGAGGGTGCGCAGGATGCAGTCATGGCAACG
ATTCGGCGACTGCGTCGCCCAGAGACAACCAAACAGGATTTGCGCGATAATTTTGCGACCCTGACGTTGGGGTCTGGTGG
TGCAGCAATGCTGCTCACCCACGAACGCTTTGCCCGGAATGGTCACCGGTTGAATGGGGTGGTGACCCTGGCGGCAACGC
AATACAACCACTTGTGTTTGGGGCAGCCGGACTATATGAAAACAGATGCCGGCGCGCTGATGCATGCCGGCGTAGAGCTG
GCCGTAGATACCTGGCGTCTGGCCCAAGAGGTCTTGCCGAACTGGAGTGACCGGCAGATTGCCCTCTACGCACCGCACCA
GGTTGGTGCACGCCACATGGCGGCGGTGACGAAAGCGCTCCACATCACACCTTCCAAGCTCTTTCTCAATTTTCCGACGT
TGGGCAATGTCGGTCCGGCAGCATTGCCGATTTCGCTGGCGCAAGCGGCAGAAGCCGGACGGCTGCGTGCAGGAGATCAT
GTCGGGCTGCTCGGCATTGGTTCCGGCTTGAACTGTTCAATGATGAGTGTGACGTGGTGA

Upstream 100 bases:

>100_bases
GAGGAAGGTTTAGAGCGCACGTTTGCCCTGACAGGCAGCCAGCCGTAAACGAGAGCACCGTTTCAGCAATCTCCAATCAT
TACCGAACAGGGAGGATTTC

Downstream 100 bases:

>100_bases
GAGCGATCCTTGAGTGATGCAGTGCATCATTGGCTGGCACCGGATATGTGGTGAACGGGGCGGGTTCTAAACCCGCCCCT
ACACGTTCATGTTGCCATAG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLFRHVMIEAVSYVLAPHRITSDWIEDQIAETMERLRFPRGKLEALSGIRERRFWDEGTLPSTVATMAAERLLDQVAIDR
ERIGLLINTSVCQDYLEPSTACFVHRNLGLSPRAINYDVRNACLGFLNGMAIAGMMIEAGTIEYALIVDGEGAQDAVMAT
IRRLRRPETTKQDLRDNFATLTLGSGGAAMLLTHERFARNGHRLNGVVTLAATQYNHLCLGQPDYMKTDAGALMHAGVEL
AVDTWRLAQEVLPNWSDRQIALYAPHQVGARHMAAVTKALHITPSKLFLNFPTLGNVGPAALPISLAQAAEAGRLRAGDH
VGLLGIGSGLNCSMMSVTW

Sequences:

>Translated_339_residues
MLFRHVMIEAVSYVLAPHRITSDWIEDQIAETMERLRFPRGKLEALSGIRERRFWDEGTLPSTVATMAAERLLDQVAIDR
ERIGLLINTSVCQDYLEPSTACFVHRNLGLSPRAINYDVRNACLGFLNGMAIAGMMIEAGTIEYALIVDGEGAQDAVMAT
IRRLRRPETTKQDLRDNFATLTLGSGGAAMLLTHERFARNGHRLNGVVTLAATQYNHLCLGQPDYMKTDAGALMHAGVEL
AVDTWRLAQEVLPNWSDRQIALYAPHQVGARHMAAVTKALHITPSKLFLNFPTLGNVGPAALPISLAQAAEAGRLRAGDH
VGLLGIGSGLNCSMMSVTW
>Mature_339_residues
MLFRHVMIEAVSYVLAPHRITSDWIEDQIAETMERLRFPRGKLEALSGIRERRFWDEGTLPSTVATMAAERLLDQVAIDR
ERIGLLINTSVCQDYLEPSTACFVHRNLGLSPRAINYDVRNACLGFLNGMAIAGMMIEAGTIEYALIVDGEGAQDAVMAT
IRRLRRPETTKQDLRDNFATLTLGSGGAAMLLTHERFARNGHRLNGVVTLAATQYNHLCLGQPDYMKTDAGALMHAGVEL
AVDTWRLAQEVLPNWSDRQIALYAPHQVGARHMAAVTKALHITPSKLFLNFPTLGNVGPAALPISLAQAAEAGRLRAGDH
VGLLGIGSGLNCSMMSVTW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=295, Percent_Identity=26.1016949152542, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37141; Mature: 37141

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRHVMIEAVSYVLAPHRITSDWIEDQIAETMERLRFPRGKLEALSGIRERRFWDEGTL
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
PSTVATMAAERLLDQVAIDRERIGLLINTSVCQDYLEPSTACFVHRNLGLSPRAINYDVR
HHHHHHHHHHHHHHHHHCCHHHHCEEEEHHHHHHHHCCCCEEEEECCCCCCCCEECHHHH
NACLGFLNGMAIAGMMIEAGTIEYALIVDGEGAQDAVMATIRRLRRPETTKQDLRDNFAT
HHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCEE
LTLGSGGAAMLLTHERFARNGHRLNGVVTLAATQYNHLCLGQPDYMKTDAGALMHAGVEL
EEECCCCEEEEEEHHHHHCCCCEECEEEEEEEECCCCEECCCCCCCCCCCCHHHHCCHHH
AVDTWRLAQEVLPNWSDRQIALYAPHQVGARHMAAVTKALHITPSKLFLNFPTLGNVGPA
HHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCH
ALPISLAQAAEAGRLRAGDHVGLLGIGSGLNCSMMSVTW
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MLFRHVMIEAVSYVLAPHRITSDWIEDQIAETMERLRFPRGKLEALSGIRERRFWDEGTL
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
PSTVATMAAERLLDQVAIDRERIGLLINTSVCQDYLEPSTACFVHRNLGLSPRAINYDVR
HHHHHHHHHHHHHHHHHCCHHHHCEEEEHHHHHHHHCCCCEEEEECCCCCCCCEECHHHH
NACLGFLNGMAIAGMMIEAGTIEYALIVDGEGAQDAVMATIRRLRRPETTKQDLRDNFAT
HHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCEE
LTLGSGGAAMLLTHERFARNGHRLNGVVTLAATQYNHLCLGQPDYMKTDAGALMHAGVEL
EEECCCCEEEEEEHHHHHCCCCEECEEEEEEEECCCCEECCCCCCCCCCCCHHHHCCHHH
AVDTWRLAQEVLPNWSDRQIALYAPHQVGARHMAAVTKALHITPSKLFLNFPTLGNVGPA
HHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCH
ALPISLAQAAEAGRLRAGDHVGLLGIGSGLNCSMMSVTW
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA