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The map label for this gene is apbE [H]

Identifier: 222527019

GI number: 222527019

Start: 4730066

End: 4731013

Strand: Reverse

Name: apbE [H]

Synonym: Chy400_3798

Alternate gene names: 222527019

Gene position: 4731013-4730066 (Counterclockwise)

Preceding gene: 222527020

Following gene: 222527018

Centisome position: 89.79

GC content: 61.18

Gene sequence:

>948_bases
ATGCAGCAGATCAGTTTTCGGGCGATGGGTTCGACGATCACCATTATCGTGGATAGTGCCGATCCAACCGCCCGCAGTGC
GCTTACATCGGCACGAAAAATCTTTCTGCACCACGAGCAGATCCTCAGCCGGTTTCGTCCGCAGAGCGAATTGAGTGTAC
TCAACCGTGCCGCCGGGCAAGGGCCGCGCCGGGTTGGACGGACACTCTGGCAGGCGGTTTGTCACGCCCTGCGGATTGCC
CGTCTGAGTCAGGGCCTGGTGACGCCAACGGTCGGTGCAGCGTTGATCGAGGCCGGCTATGACCGTGATTTCGGTATGCT
TATTGCATCGCACAGGCAATCTATTCAGACCCCGGTTGCGATCCCCTCCTGGCAGCGTATCACGTGTGATCCTTACCGAC
GTACCATCGCGTTACCGGCAGGGGTACAGCTTGATCTGGGTGGCAGTGCCAAGGGTTGGACGGCGGCCATCGTTGCGCGC
CGGCTGGGAAAACGTTTTCCCTCCCTGGTTGATGCCGGTGGTGACATCGCACTCAGCGGGCCGCGCCGCGATGGTACACC
CTGGCCGGTAGAAATTGCCGATCCACGGCAGCCTGATACCGGCATCGAGCTGCTGCTGGTTCGGCGCGGAGGAATTGCGA
CATCGGGGATAGATTATCGGCGCTGGCAGCACAACGGGCGCTGGATGCACCATGTGATTGACCCATGTACCGGTGCACCG
GCGCAAACCGACGTGCTGGCAGCCACGGTCATTGCGTCCAGCCTGCCGCTTGCCGAGATGGCGGCGAAGATGGTTGTGAT
ACTCGGAAGTGACGAGGGTTTGCGCTGGTTGAATGCCCGACCTGATCTCGCCGGCCTGCTGGTAACTACCGACGGTACAG
TGATACGCACTGCTACCCTCACCCGCTGCTGCTGGCGTCCGGCTGTTGAATCGGCTGCAAGCCTCTAG

Upstream 100 bases:

>100_bases
CCGGCTCAACCGGCCCTGCGTGAGGTGACCGTACCGGCACCGGCGCCTCGTCCGGCACCCGTCGCGCGTACTCGTTCATC
GCGTTGATACGGAGACAGCT

Downstream 100 bases:

>100_bases
TATCAACTTAGTGAGGTGTTCCATGACAAATCCAGCTTCCTCATCTGAACTCACAGAAGCCAAAAAGGTGGCTCCTGGCC
GTCCTGCGCGGATGGTGACA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQQISFRAMGSTITIIVDSADPTARSALTSARKIFLHHEQILSRFRPQSELSVLNRAAGQGPRRVGRTLWQAVCHALRIA
RLSQGLVTPTVGAALIEAGYDRDFGMLIASHRQSIQTPVAIPSWQRITCDPYRRTIALPAGVQLDLGGSAKGWTAAIVAR
RLGKRFPSLVDAGGDIALSGPRRDGTPWPVEIADPRQPDTGIELLLVRRGGIATSGIDYRRWQHNGRWMHHVIDPCTGAP
AQTDVLAATVIASSLPLAEMAAKMVVILGSDEGLRWLNARPDLAGLLVTTDGTVIRTATLTRCCWRPAVESAASL

Sequences:

>Translated_315_residues
MQQISFRAMGSTITIIVDSADPTARSALTSARKIFLHHEQILSRFRPQSELSVLNRAAGQGPRRVGRTLWQAVCHALRIA
RLSQGLVTPTVGAALIEAGYDRDFGMLIASHRQSIQTPVAIPSWQRITCDPYRRTIALPAGVQLDLGGSAKGWTAAIVAR
RLGKRFPSLVDAGGDIALSGPRRDGTPWPVEIADPRQPDTGIELLLVRRGGIATSGIDYRRWQHNGRWMHHVIDPCTGAP
AQTDVLAATVIASSLPLAEMAAKMVVILGSDEGLRWLNARPDLAGLLVTTDGTVIRTATLTRCCWRPAVESAASL
>Mature_315_residues
MQQISFRAMGSTITIIVDSADPTARSALTSARKIFLHHEQILSRFRPQSELSVLNRAAGQGPRRVGRTLWQAVCHALRIA
RLSQGLVTPTVGAALIEAGYDRDFGMLIASHRQSIQTPVAIPSWQRITCDPYRRTIALPAGVQLDLGGSAKGWTAAIVAR
RLGKRFPSLVDAGGDIALSGPRRDGTPWPVEIADPRQPDTGIELLLVRRGGIATSGIDYRRWQHNGRWMHHVIDPCTGAP
AQTDVLAATVIASSLPLAEMAAKMVVILGSDEGLRWLNARPDLAGLLVTTDGTVIRTATLTRCCWRPAVESAASL

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=278, Percent_Identity=26.2589928057554, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34038; Mature: 34038

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQISFRAMGSTITIIVDSADPTARSALTSARKIFLHHEQILSRFRPQSELSVLNRAAGQ
CCCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GPRRVGRTLWQAVCHALRIARLSQGLVTPTVGAALIEAGYDRDFGMLIASHRQSIQTPVA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
IPSWQRITCDPYRRTIALPAGVQLDLGGSAKGWTAAIVARRLGKRFPSLVDAGGDIALSG
CCCCCCEECCHHHEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCHHHHCCCCCEEECC
PRRDGTPWPVEIADPRQPDTGIELLLVRRGGIATSGIDYRRWQHNGRWMHHVIDPCTGAP
CCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCEEEHHHCCCCCCC
AQTDVLAATVIASSLPLAEMAAKMVVILGSDEGLRWLNARPDLAGLLVTTDGTVIRTATL
CHHHHHHHHHHHHCCCHHHHHCEEEEEEECCCCCEEECCCCCCEEEEEECCCCEEEHHHH
TRCCWRPAVESAASL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQISFRAMGSTITIIVDSADPTARSALTSARKIFLHHEQILSRFRPQSELSVLNRAAGQ
CCCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GPRRVGRTLWQAVCHALRIARLSQGLVTPTVGAALIEAGYDRDFGMLIASHRQSIQTPVA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
IPSWQRITCDPYRRTIALPAGVQLDLGGSAKGWTAAIVARRLGKRFPSLVDAGGDIALSG
CCCCCCEECCHHHEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCHHHHCCCCCEEECC
PRRDGTPWPVEIADPRQPDTGIELLLVRRGGIATSGIDYRRWQHNGRWMHHVIDPCTGAP
CCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCEEEHHHCCCCCCC
AQTDVLAATVIASSLPLAEMAAKMVVILGSDEGLRWLNARPDLAGLLVTTDGTVIRTATL
CHHHHHHHHHHHHCCCHHHHHCEEEEEEECCCCCEEECCCCCCEEEEEECCCCEEEHHHH
TRCCWRPAVESAASL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]