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The map label for this gene is polC [H]

Identifier: 222526189

GI number: 222526189

Start: 3641098

End: 3641796

Strand: Direct

Name: polC [H]

Synonym: Chy400_2948

Alternate gene names: 222526189

Gene position: 3641098-3641796 (Clockwise)

Preceding gene: 222526188

Following gene: 222526190

Centisome position: 69.1

GC content: 56.94

Gene sequence:

>699_bases
ATGGCGTTTTGGGCGAGACTGTTTCAACGCACGCCACCGGCTGATTTTGTACGGGCCTACGAAGCCTTTCCCGAACCTGA
TCGGCGTTTACCATGGCGGGAAGTTCCCTACACCGTGATCGATGTCGAAACCACCGGCCTTGATACCCGTCATGATGCCT
TGATTGCCGTTGGTGCCGTGAATATCGAGAATGGGCGGGTCTTGCTCAAACAGACCTGGTATTCGCTGATCAAGCCACCT
CCTGATCGTGAACCGAGTGTTGAGAGTATTCGGGTGCATCACTTGACACCAGCCGAGCTACAGAATGCGCCGCCCGCCGA
AGAGGTGCTGGCCGAGTTGCTGCGTCGCATTGCCGGGCGGGTGTTAGTTGTGCATGTGGCGCAAGTGGATGTTCGTTTCA
TTAATGCCGCGCTGAAGCCGTTTGGTGGTAAGTTGCGGCGACCAATTCTGGATACTGCTCGTCTGGCTCTCACACTCCAT
ATGAATGCGCGCTGGTTGGGCGAACAACCACACGATATGCCCGATCCCGCAATTGAGTTGCGTGGTCTGGCAACGGCGCT
TGGGTTGCCGGTGTATGCCCAGCACAACGCGCTGAATGACGCAGTGACAACAGCTCAGCTCTTTATCGCGCAGGCGACAA
TACTGGCAGATCAGGGGCGGAGTAATCTGGCCGGCCTGATCAGGGCTGGAGGGGTATAG

Upstream 100 bases:

>100_bases
GTGAACGGCGTGAAGTCAAAGAGTCCTTGCAGGCGATTGCCTCTGTCCAACGTGGCGTAGCGCTGATGTTTCAAACTGAC
CGACTGGCGTAGAGGTGTCT

Downstream 100 bases:

>100_bases
GCACATCTGTGGCTGGTCGTCGCTGGGTGTGTGTTTAGTTGATAGTCTGACAATGGCGATGCCAGTGGTGTTGCCAGGCG
AGAGCTGTGCAAGAGAACTT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAFWARLFQRTPPADFVRAYEAFPEPDRRLPWREVPYTVIDVETTGLDTRHDALIAVGAVNIENGRVLLKQTWYSLIKPP
PDREPSVESIRVHHLTPAELQNAPPAEEVLAELLRRIAGRVLVVHVAQVDVRFINAALKPFGGKLRRPILDTARLALTLH
MNARWLGEQPHDMPDPAIELRGLATALGLPVYAQHNALNDAVTTAQLFIAQATILADQGRSNLAGLIRAGGV

Sequences:

>Translated_232_residues
MAFWARLFQRTPPADFVRAYEAFPEPDRRLPWREVPYTVIDVETTGLDTRHDALIAVGAVNIENGRVLLKQTWYSLIKPP
PDREPSVESIRVHHLTPAELQNAPPAEEVLAELLRRIAGRVLVVHVAQVDVRFINAALKPFGGKLRRPILDTARLALTLH
MNARWLGEQPHDMPDPAIELRGLATALGLPVYAQHNALNDAVTTAQLFIAQATILADQGRSNLAGLIRAGGV
>Mature_231_residues
AFWARLFQRTPPADFVRAYEAFPEPDRRLPWREVPYTVIDVETTGLDTRHDALIAVGAVNIENGRVLLKQTWYSLIKPPP
DREPSVESIRVHHLTPAELQNAPPAEEVLAELLRRIAGRVLVVHVAQVDVRFINAALKPFGGKLRRPILDTARLALTLHM
NARWLGEQPHDMPDPAIELRGLATALGLPVYAQHNALNDAVTTAQLFIAQATILADQGRSNLAGLIRAGGV

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25694; Mature: 25563

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFWARLFQRTPPADFVRAYEAFPEPDRRLPWREVPYTVIDVETTGLDTRHDALIAVGAV
CHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHCCEEEEEEEECCCCCCCCEEEEEEEE
NIENGRVLLKQTWYSLIKPPPDREPSVESIRVHHLTPAELQNAPPAEEVLAELLRRIAGR
EECCCCEEHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHCC
VLVVHVAQVDVRFINAALKPFGGKLRRPILDTARLALTLHMNARWLGEQPHDMPDPAIEL
EEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEEEECCEECCCCCCCCCCHHHHH
RGLATALGLPVYAQHNALNDAVTTAQLFIAQATILADQGRSNLAGLIRAGGV
HHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
AFWARLFQRTPPADFVRAYEAFPEPDRRLPWREVPYTVIDVETTGLDTRHDALIAVGAV
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHCCEEEEEEEECCCCCCCCEEEEEEEE
NIENGRVLLKQTWYSLIKPPPDREPSVESIRVHHLTPAELQNAPPAEEVLAELLRRIAGR
EECCCCEEHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHCC
VLVVHVAQVDVRFINAALKPFGGKLRRPILDTARLALTLHMNARWLGEQPHDMPDPAIEL
EEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEEEECCEECCCCCCCCCCHHHHH
RGLATALGLPVYAQHNALNDAVTTAQLFIAQATILADQGRSNLAGLIRAGGV
HHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]