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The map label for this gene is ileS [H]

Identifier: 222526152

GI number: 222526152

Start: 3594663

End: 3597863

Strand: Direct

Name: ileS [H]

Synonym: Chy400_2909

Alternate gene names: 222526152

Gene position: 3594663-3597863 (Clockwise)

Preceding gene: 222526151

Following gene: 222526153

Centisome position: 68.22

GC content: 57.67

Gene sequence:

>3201_bases
ATGTTCAGACCAGTTGACACTAACGTGAAGTTCCCCCAGCTCGAAGAAGAGGTGATTGCCTGGTGGGAAGCGAACAACAT
TGTCGCTAAATCGCTGGCAGCCGGCGACAAGCCGTTTGTCTTTTACGAGGGACCACCAACCTCGAACGGTCGCCCCGGTC
TGCATCACACCATCTCACGCAGTTTCAAAGATGTGATCCTGCGCTATCGCGCTATGCAGGGTTATCGGATCATCGGTCGG
CGCGAAGGCTGGGATACACACGGCCTGCCGGTTGAGATCGAGATCGAGAAGAAGCTTGGCTTCAGCGGCAAACCGGATAT
CGAGCGCTTTGGGATTGCCGAATTTAACCGTCTCTGCCGCGAAAGTGTCTGGGAGTATATTCAGGAGTGGAAGGCATTTA
CCAAGCGCATCGCCTTCTGGCTCAGCGAAGATGCCTACATCACCTACGAAAACGATTATATTGAGTCGACGTGGTGGATC
TTCCGGCAACTGTGGGATCGCGGGCTACTCTTCCGCGATTACAAGGTGACGATGCACTGCCCGCGTTGTGGCACGAGTCT
GAGCGACCACGAAGTGAGCCTCGGTGCCCGCGATGATGTTGATGATCCGAGTGTGTACATCAAGTTTCGGGTAAACGGCT
TCACCGCACCGCCACCTGCCGTTGATGGTACCCTCGAAGGGGCATTTCTGGTGGCCTGGACGACCACACCCTGGACGTTG
CCGGCTAATGTGGCCCTGGCCGTGAAGCATGATGCTGAATATGTCGAAGTCGAACACAACGGCGAGCGGCTGGTGATGGC
TGCCGCATTGGTCGGCAATGTCTTGCCGGCTGAGAGCTTTACAGTGTTGCGTCACTTCCGCGGCAATGATCTGGTTGGTC
TGCGCTATGAGCCACTCTTCCGGGGTGTGCCGGGTGCCGGTGACACCGTCGATTGGGATACTGCCTACCGGGTGATCGCC
GACGAGATTGTCAGCCTCGATGATGGTACCGGCATCGTGCATATCGCGCCGGCTTACGGTGACCTGGAGGTTGGCCGCAA
ACACGGTCTACCCACCCTCTTCTCGGTTGGGTTGGACGGGCGCGTGCTGCCTGAATTCGCCGAACTCGGCTTTGCCGGTA
AGTTTTTCAAAGAGGCCGATCCCGATATTACGCGGAATCTGAAACAACGGGGTTTACTCCTGCGCAGTGGCCGGGTCCGT
CACTACTATCCCTTCTGCTGGCGCTGTAGTACACCGCTGCTCTACTACGCCAAGCGCTCGTGGTACATTCGCACGACTGC
ATTCAAGGCTGATCTGGTTGCCAATAATCAGCAGATCCACTGGGTTCCAGATCATATCCGCGATGGCCGCTTCGGTAACT
GGCTTGAGAATAACATCGACTGGGCTATCAGCCGTGAGCGCTATTGGGGAACGCCCATCCCGATCTGGACTAACGCCGAT
GGCTCGCATATGGTCTGTATCGGTTCGCTGGCCGAACTGGAAGAGAAGGTCGGGCGTTCACTGCGCGATCTTGATCTCCA
CCGTCCTTACATCGATGAGGTGGTGTGGGAAGACCCAGAACACGGCCTGATGCGGCGTATTCCCGACGTTGCCGACTGCT
GGTTTGACAGTGGTTCGATGCCAGTTGCGCAGTGGCACTATCCGTTTGAAAACCGCGACATCTTCGAGATGGCCCACCCC
GCCGATTACATCTGCGAGGCGGTTGATCAGACGCGGGGCTGGTTCTATACCTTGCACGCGATCAGCACGCTGCTCTTTGA
CCGGCCAGCGTTCAAGAATGTGATCTGTCTCGGTCATATTCTTGACGAGAACGGTCTGAAGATGAGCAAGAGCAAGGGCA
ACGTGATCGAGCCGGAAGAGGTGATCAATGCTTACGGGGTTGATGCGTTGCGCTGGTACCTGTTCACCGCTGCGCCTCCC
GGCAATGCTCGCCGCTTCAGCATGGCACTGGTCAGCGAGAGTATGCGGAAGTTCCTGCTAACCCTCTGGAATACGTATGC
CTTCTTCGTGACCTACGCCAATCTCGATCAGTGGCAGCCGGGCAGCAACCGTACTGCCGAACTGCAACCGATTGATCGCT
GGGCACTGGCAGCACTCAATCAGCTCGTCCAGCAAGTCACGACATGCTTCGAGGAGTACGATGTCTATACAGCGGCCAAT
GCCATCGAACATTTCGTTGATGAGCTGTCGAACTGGTATGTGCGCCGTAATCGCCGTCGCTTCTGGAAGAGTGAAGCTGA
TGCTGACAAAGAGGCAGCCTACCAGACACTCTACACCTGTCTGGTGACGGTGGCGAAGCTGGCGGCACCGTTTATTCCGT
TCGTTAGCGAGGAGATCTACCGCAACCTGGTCGCCGAACGTGATCCCTCTGCTGCCGAGAGTGTGCATCTTGCCCAGTGG
CCACGTGTCGATCAGTCACTGCTCGATGCGCAACTGGTCAGCGATACTGAAGCACTGCTCACCGCCGTTTCGCTGGGTCG
GTCAGCGCGCAAGCAGGCCAACTTGAAAGTTCGCCAGCCGCTGAGTGAAATCTGGCTGCGGGCCAGCACGCCGGCAGTCC
TCAACGGTGTACGGCGCTTCGAGAGCGAGTTGCGTGATGAACTCAATGTGAAGGCAGTGCGCTACCTTGACGCCAGTAGT
GCTGTGGTGGAATACCGGTTGAAGCCAAATCTGCGCCTGGTCGGCAAGAAGTTCGGCAAGCTGGTACCGGCCCTCACCGC
TACCCTGCGCGACCTGAACGGTGATGCAGCGCGGGCCGTGGCCCAGGCGGTAGAAGCCGGTCAGCCTGTCCACCTGACTG
TTGATGGTCAGACGGTAGAACTGTTGGCTGAGGAAATCCTGGTCGAGAGCAGTGCACCGGCAGGGTACGTCGTTGCCGAG
GCCGATGGGATGCTGGTCGCATTGAACACCACCGTCACCGACGAGTTGCGGCTCGAAGGCGCGGCCCGCGATCTGGTGCG
TTATGTGCAGGATGCACGCAAGAGTGCAGGGCTGGCGATCAGTGATCGCATCCATCTCTTCCTCGACACTGCCGACCAGA
GTGAGTTGCTTGCCAGTACGCTGGCCCAGTACGAGCAATACCTCAAGACTGAGACACTGGCTCTGGAACTCACTGTTGGC
ACACCGCCGACCAATGCCTACACCGAAACCCATGAATTCGGTGACGGTGAAGTGACGGTCGGCGTGGTGAAAGCAGGCTA
G

Upstream 100 bases:

>100_bases
GGCAGGCGCCACAGCATCGAATTGGGGTGGTACCGCGGGGTTAATCTGCCTCGTCCCCTGTTGGGGACGGGGCTTTTGGT
TTGGTTCGGATGGAGGTTTC

Downstream 100 bases:

>100_bases
CGCCGATCCAGACCCCAATGCTCTCCGTGTCTCTGTGGTGAAATCGTACCGCAGAGGCACGGATGGTTTTTTTATTCCGT
CTGACTCCTTCTCTTGAATC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1066; Mature: 1066

Protein sequence:

>1066_residues
MFRPVDTNVKFPQLEEEVIAWWEANNIVAKSLAAGDKPFVFYEGPPTSNGRPGLHHTISRSFKDVILRYRAMQGYRIIGR
REGWDTHGLPVEIEIEKKLGFSGKPDIERFGIAEFNRLCRESVWEYIQEWKAFTKRIAFWLSEDAYITYENDYIESTWWI
FRQLWDRGLLFRDYKVTMHCPRCGTSLSDHEVSLGARDDVDDPSVYIKFRVNGFTAPPPAVDGTLEGAFLVAWTTTPWTL
PANVALAVKHDAEYVEVEHNGERLVMAAALVGNVLPAESFTVLRHFRGNDLVGLRYEPLFRGVPGAGDTVDWDTAYRVIA
DEIVSLDDGTGIVHIAPAYGDLEVGRKHGLPTLFSVGLDGRVLPEFAELGFAGKFFKEADPDITRNLKQRGLLLRSGRVR
HYYPFCWRCSTPLLYYAKRSWYIRTTAFKADLVANNQQIHWVPDHIRDGRFGNWLENNIDWAISRERYWGTPIPIWTNAD
GSHMVCIGSLAELEEKVGRSLRDLDLHRPYIDEVVWEDPEHGLMRRIPDVADCWFDSGSMPVAQWHYPFENRDIFEMAHP
ADYICEAVDQTRGWFYTLHAISTLLFDRPAFKNVICLGHILDENGLKMSKSKGNVIEPEEVINAYGVDALRWYLFTAAPP
GNARRFSMALVSESMRKFLLTLWNTYAFFVTYANLDQWQPGSNRTAELQPIDRWALAALNQLVQQVTTCFEEYDVYTAAN
AIEHFVDELSNWYVRRNRRRFWKSEADADKEAAYQTLYTCLVTVAKLAAPFIPFVSEEIYRNLVAERDPSAAESVHLAQW
PRVDQSLLDAQLVSDTEALLTAVSLGRSARKQANLKVRQPLSEIWLRASTPAVLNGVRRFESELRDELNVKAVRYLDASS
AVVEYRLKPNLRLVGKKFGKLVPALTATLRDLNGDAARAVAQAVEAGQPVHLTVDGQTVELLAEEILVESSAPAGYVVAE
ADGMLVALNTTVTDELRLEGAARDLVRYVQDARKSAGLAISDRIHLFLDTADQSELLASTLAQYEQYLKTETLALELTVG
TPPTNAYTETHEFGDGEVTVGVVKAG

Sequences:

>Translated_1066_residues
MFRPVDTNVKFPQLEEEVIAWWEANNIVAKSLAAGDKPFVFYEGPPTSNGRPGLHHTISRSFKDVILRYRAMQGYRIIGR
REGWDTHGLPVEIEIEKKLGFSGKPDIERFGIAEFNRLCRESVWEYIQEWKAFTKRIAFWLSEDAYITYENDYIESTWWI
FRQLWDRGLLFRDYKVTMHCPRCGTSLSDHEVSLGARDDVDDPSVYIKFRVNGFTAPPPAVDGTLEGAFLVAWTTTPWTL
PANVALAVKHDAEYVEVEHNGERLVMAAALVGNVLPAESFTVLRHFRGNDLVGLRYEPLFRGVPGAGDTVDWDTAYRVIA
DEIVSLDDGTGIVHIAPAYGDLEVGRKHGLPTLFSVGLDGRVLPEFAELGFAGKFFKEADPDITRNLKQRGLLLRSGRVR
HYYPFCWRCSTPLLYYAKRSWYIRTTAFKADLVANNQQIHWVPDHIRDGRFGNWLENNIDWAISRERYWGTPIPIWTNAD
GSHMVCIGSLAELEEKVGRSLRDLDLHRPYIDEVVWEDPEHGLMRRIPDVADCWFDSGSMPVAQWHYPFENRDIFEMAHP
ADYICEAVDQTRGWFYTLHAISTLLFDRPAFKNVICLGHILDENGLKMSKSKGNVIEPEEVINAYGVDALRWYLFTAAPP
GNARRFSMALVSESMRKFLLTLWNTYAFFVTYANLDQWQPGSNRTAELQPIDRWALAALNQLVQQVTTCFEEYDVYTAAN
AIEHFVDELSNWYVRRNRRRFWKSEADADKEAAYQTLYTCLVTVAKLAAPFIPFVSEEIYRNLVAERDPSAAESVHLAQW
PRVDQSLLDAQLVSDTEALLTAVSLGRSARKQANLKVRQPLSEIWLRASTPAVLNGVRRFESELRDELNVKAVRYLDASS
AVVEYRLKPNLRLVGKKFGKLVPALTATLRDLNGDAARAVAQAVEAGQPVHLTVDGQTVELLAEEILVESSAPAGYVVAE
ADGMLVALNTTVTDELRLEGAARDLVRYVQDARKSAGLAISDRIHLFLDTADQSELLASTLAQYEQYLKTETLALELTVG
TPPTNAYTETHEFGDGEVTVGVVKAG
>Mature_1066_residues
MFRPVDTNVKFPQLEEEVIAWWEANNIVAKSLAAGDKPFVFYEGPPTSNGRPGLHHTISRSFKDVILRYRAMQGYRIIGR
REGWDTHGLPVEIEIEKKLGFSGKPDIERFGIAEFNRLCRESVWEYIQEWKAFTKRIAFWLSEDAYITYENDYIESTWWI
FRQLWDRGLLFRDYKVTMHCPRCGTSLSDHEVSLGARDDVDDPSVYIKFRVNGFTAPPPAVDGTLEGAFLVAWTTTPWTL
PANVALAVKHDAEYVEVEHNGERLVMAAALVGNVLPAESFTVLRHFRGNDLVGLRYEPLFRGVPGAGDTVDWDTAYRVIA
DEIVSLDDGTGIVHIAPAYGDLEVGRKHGLPTLFSVGLDGRVLPEFAELGFAGKFFKEADPDITRNLKQRGLLLRSGRVR
HYYPFCWRCSTPLLYYAKRSWYIRTTAFKADLVANNQQIHWVPDHIRDGRFGNWLENNIDWAISRERYWGTPIPIWTNAD
GSHMVCIGSLAELEEKVGRSLRDLDLHRPYIDEVVWEDPEHGLMRRIPDVADCWFDSGSMPVAQWHYPFENRDIFEMAHP
ADYICEAVDQTRGWFYTLHAISTLLFDRPAFKNVICLGHILDENGLKMSKSKGNVIEPEEVINAYGVDALRWYLFTAAPP
GNARRFSMALVSESMRKFLLTLWNTYAFFVTYANLDQWQPGSNRTAELQPIDRWALAALNQLVQQVTTCFEEYDVYTAAN
AIEHFVDELSNWYVRRNRRRFWKSEADADKEAAYQTLYTCLVTVAKLAAPFIPFVSEEIYRNLVAERDPSAAESVHLAQW
PRVDQSLLDAQLVSDTEALLTAVSLGRSARKQANLKVRQPLSEIWLRASTPAVLNGVRRFESELRDELNVKAVRYLDASS
AVVEYRLKPNLRLVGKKFGKLVPALTATLRDLNGDAARAVAQAVEAGQPVHLTVDGQTVELLAEEILVESSAPAGYVVAE
ADGMLVALNTTVTDELRLEGAARDLVRYVQDARKSAGLAISDRIHLFLDTADQSELLASTLAQYEQYLKTETLALELTVG
TPPTNAYTETHEFGDGEVTVGVVKAG

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1068, Percent_Identity=36.5168539325843, Blast_Score=657, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1068, Percent_Identity=36.5168539325843, Blast_Score=657, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=791, Percent_Identity=27.6864728192162, Blast_Score=270, Evalue=5e-72,
Organism=Homo sapiens, GI5454158, Length=863, Percent_Identity=24.1019698725377, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI268370295, Length=811, Percent_Identity=21.9482120838471, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI268370293, Length=817, Percent_Identity=21.9094247246022, Blast_Score=133, Evalue=8e-31,
Organism=Homo sapiens, GI268370297, Length=811, Percent_Identity=21.9482120838471, Blast_Score=133, Evalue=1e-30,
Organism=Escherichia coli, GI2367096, Length=837, Percent_Identity=27.8375149342891, Blast_Score=310, Evalue=4e-85,
Organism=Escherichia coli, GI1790708, Length=920, Percent_Identity=23.9130434782609, Blast_Score=174, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17541896, Length=1042, Percent_Identity=36.468330134357, Blast_Score=620, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71980946, Length=905, Percent_Identity=25.414364640884, Blast_Score=228, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17510661, Length=870, Percent_Identity=22.183908045977, Blast_Score=144, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1045, Percent_Identity=36.3636363636364, Blast_Score=628, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6325217, Length=794, Percent_Identity=25.9445843828715, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6321531, Length=873, Percent_Identity=22.680412371134, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574730, Length=1072, Percent_Identity=36.9402985074627, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24668547, Length=1072, Percent_Identity=36.9402985074627, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24668543, Length=1072, Percent_Identity=36.9402985074627, Blast_Score=627, Evalue=1e-179,
Organism=Drosophila melanogaster, GI281366294, Length=787, Percent_Identity=27.9542566709022, Blast_Score=259, Evalue=9e-69,
Organism=Drosophila melanogaster, GI17864482, Length=929, Percent_Identity=23.2508073196986, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24653289, Length=929, Percent_Identity=23.2508073196986, Blast_Score=171, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21355675, Length=956, Percent_Identity=21.652719665272, Blast_Score=131, Evalue=2e-30,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 120628; Mature: 120628

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRPVDTNVKFPQLEEEVIAWWEANNIVAKSLAAGDKPFVFYEGPPTSNGRPGLHHTISR
CCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHH
SFKDVILRYRAMQGYRIIGRREGWDTHGLPVEIEIEKKLGFSGKPDIERFGIAEFNRLCR
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEHHCCCCCCCCCHHHCCHHHHHHHHH
ESVWEYIQEWKAFTKRIAFWLSEDAYITYENDYIESTWWIFRQLWDRGLLFRDYKVTMHC
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEC
PRCGTSLSDHEVSLGARDDVDDPSVYIKFRVNGFTAPPPAVDGTLEGAFLVAWTTTPWTL
CCCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCC
PANVALAVKHDAEYVEVEHNGERLVMAAALVGNVLPAESFTVLRHFRGNDLVGLRYEPLF
CCCEEEEEECCCEEEEEECCCCEEEEHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECHHH
RGVPGAGDTVDWDTAYRVIADEIVSLDDGTGIVHIAPAYGDLEVGRKHGLPTLFSVGLDG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHCCCCCEEECCCCC
RVLPEFAELGFAGKFFKEADPDITRNLKQRGLLLRSGRVRHYYPFCWRCSTPLLYYAKRS
CCCHHHHHCCCCHHHHHCCCCHHHHHHHHCCEEEECCCCCEECCEEEECCCCEEEEECCC
WYIRTTAFKADLVANNQQIHWVPDHIRDGRFGNWLENNIDWAISRERYWGTPIPIWTNAD
EEEEEEEEEEHEEECCCEEEECCHHHCCCCCCCHHHCCCCEEEECCCCCCCCCCEEECCC
GSHMVCIGSLAELEEKVGRSLRDLDLHRPYIDEVVWEDPEHGLMRRIPDVADCWFDSGSM
CCEEEEECCHHHHHHHHCCHHHHHHCCCCHHHHHHCCCCCCHHHHHCCCHHHHHCCCCCC
PVAQWHYPFENRDIFEMAHPADYICEAVDQTRGWFYTLHAISTLLFDRPAFKNVICLGHI
CCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHCEEEEEEE
LDENGLKMSKSKGNVIEPEEVINAYGVDALRWYLFTAAPPGNARRFSMALVSESMRKFLL
ECCCCCEEECCCCCCCCHHHHHHHHCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TLWNTYAFFVTYANLDQWQPGSNRTAELQPIDRWALAALNQLVQQVTTCFEEYDVYTAAN
HHHHHHEEEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEHFVDELSNWYVRRNRRRFWKSEADADKEAAYQTLYTCLVTVAKLAAPFIPFVSEEIY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNLVAERDPSAAESVHLAQWPRVDQSLLDAQLVSDTEALLTAVSLGRSARKQANLKVRQP
HHHHHCCCCCHHHCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHCC
LSEIWLRASTPAVLNGVRRFESELRDELNVKAVRYLDASSAVVEYRLKPNLRLVGKKFGK
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHH
LVPALTATLRDLNGDAARAVAQAVEAGQPVHLTVDGQTVELLAEEILVESSAPAGYVVAE
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEE
ADGMLVALNTTVTDELRLEGAARDLVRYVQDARKSAGLAISDRIHLFLDTADQSELLAST
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEEECCCHHHHHHHH
LAQYEQYLKTETLALELTVGTPPTNAYTETHEFGDGEVTVGVVKAG
HHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MFRPVDTNVKFPQLEEEVIAWWEANNIVAKSLAAGDKPFVFYEGPPTSNGRPGLHHTISR
CCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHH
SFKDVILRYRAMQGYRIIGRREGWDTHGLPVEIEIEKKLGFSGKPDIERFGIAEFNRLCR
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEHHCCCCCCCCCHHHCCHHHHHHHHH
ESVWEYIQEWKAFTKRIAFWLSEDAYITYENDYIESTWWIFRQLWDRGLLFRDYKVTMHC
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEC
PRCGTSLSDHEVSLGARDDVDDPSVYIKFRVNGFTAPPPAVDGTLEGAFLVAWTTTPWTL
CCCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCC
PANVALAVKHDAEYVEVEHNGERLVMAAALVGNVLPAESFTVLRHFRGNDLVGLRYEPLF
CCCEEEEEECCCEEEEEECCCCEEEEHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECHHH
RGVPGAGDTVDWDTAYRVIADEIVSLDDGTGIVHIAPAYGDLEVGRKHGLPTLFSVGLDG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHCCCCCEEECCCCC
RVLPEFAELGFAGKFFKEADPDITRNLKQRGLLLRSGRVRHYYPFCWRCSTPLLYYAKRS
CCCHHHHHCCCCHHHHHCCCCHHHHHHHHCCEEEECCCCCEECCEEEECCCCEEEEECCC
WYIRTTAFKADLVANNQQIHWVPDHIRDGRFGNWLENNIDWAISRERYWGTPIPIWTNAD
EEEEEEEEEEHEEECCCEEEECCHHHCCCCCCCHHHCCCCEEEECCCCCCCCCCEEECCC
GSHMVCIGSLAELEEKVGRSLRDLDLHRPYIDEVVWEDPEHGLMRRIPDVADCWFDSGSM
CCEEEEECCHHHHHHHHCCHHHHHHCCCCHHHHHHCCCCCCHHHHHCCCHHHHHCCCCCC
PVAQWHYPFENRDIFEMAHPADYICEAVDQTRGWFYTLHAISTLLFDRPAFKNVICLGHI
CCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHCEEEEEEE
LDENGLKMSKSKGNVIEPEEVINAYGVDALRWYLFTAAPPGNARRFSMALVSESMRKFLL
ECCCCCEEECCCCCCCCHHHHHHHHCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TLWNTYAFFVTYANLDQWQPGSNRTAELQPIDRWALAALNQLVQQVTTCFEEYDVYTAAN
HHHHHHEEEEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEHFVDELSNWYVRRNRRRFWKSEADADKEAAYQTLYTCLVTVAKLAAPFIPFVSEEIY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNLVAERDPSAAESVHLAQWPRVDQSLLDAQLVSDTEALLTAVSLGRSARKQANLKVRQP
HHHHHCCCCCHHHCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHCC
LSEIWLRASTPAVLNGVRRFESELRDELNVKAVRYLDASSAVVEYRLKPNLRLVGKKFGK
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHH
LVPALTATLRDLNGDAARAVAQAVEAGQPVHLTVDGQTVELLAEEILVESSAPAGYVVAE
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEE
ADGMLVALNTTVTDELRLEGAARDLVRYVQDARKSAGLAISDRIHLFLDTADQSELLAST
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEEECCCHHHHHHHH
LAQYEQYLKTETLALELTVGTPPTNAYTETHEFGDGEVTVGVVKAG
HHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA