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The map label for this gene is ykoH [H]

Identifier: 222525872

GI number: 222525872

Start: 3261977

End: 3263428

Strand: Reverse

Name: ykoH [H]

Synonym: Chy400_2625

Alternate gene names: 222525872

Gene position: 3263428-3261977 (Counterclockwise)

Preceding gene: 222525873

Following gene: 222525871

Centisome position: 61.94

GC content: 55.51

Gene sequence:

>1452_bases
ATGAAACAGCAGTGGCATAGATTATCGTTGCGGCAACGACTGGCGTTGTTGTACAGCGGCCTGCTGGCCCTGCTTTTATG
TCTACTTGGCTTCGGCTTCTACCTCGATATGCGCCAGTTTCTCTTTGAGAGCACCGGTCTGCGGATTCGAGCGCAAGCCA
AACCAGTGATCGAACAATACCTGTTTGAGCACCCTGACCCGGCTACACAGTTGCCGTTAATTGCCGAACAGTTGAGCCGT
GATCTGACCTCGCGCGATACCACCGCTCTGATCTTCGATCAGGCAGGGGCGTTGTTAGCCAGTGGTCGCCGATTACCAGA
AGAGCCGCCGGCTCAACCGGTCGAAGCTTCGTATGTCAATATGGCACTGGCCGGCCACAATAACGTGAACGTTATTCAGG
ATGATGGCGATCAGCGGATGCTGAGCCTGCTGATCCCACTACGACCGGCACCAGGAGCACCCCAAGTGTTTGGCGTGGTG
CAAATGAGCACTCCCTTAAGCCCAATTGAGACGACTCTGCAACGCCAAAGCATCATTATTGTGTCAAGTATCGTCATCGT
TCTCCTCGCAGGCAGCCTCATCGGCTACTGGTTAACCAGCTCGACGCTGCGGCCATTAAGCGACTTAATCGTTGCCTGTC
AGAAGATTGCCCAGGGCAATCTCCGCCAGCGCGTACCGGTGATTTCGCCGCACGACGAGATTGGCAAGCTGACGCAGGCT
TTTGACGAGATGGTTGAGCGCCTGGAACAAAATTTTCAGGCTCAACGACGCTTTATCGCCGACGCTGCTCACGAAATGCG
CACACCGCTAACCGCATTACGCAGCGGGCTAGAGGTGCTGTTACGCGGTGCCCAGGATGACCCGCAAACGGCCTTCCGCC
TGATCCAAAGTATGCATCGTGACGTTGTCCGCCTGTGCAATGTCAGTGAACAGTTACTCGACAAAGCCCGCTACGAGTCG
GGTCGTTCATTGAACATACAACCGGTGACAATGACCGATTTTCTCGTCGAATTTACCGCCCAGGCCCGGCTCTTAGCCGG
CGAACGACGGGTAATCCTCGAAAGCGGGCCACCCATTCAGGCCTGGATCGATGGCGACAGCGTCAAACAAGCGCTTTTTC
ACCTGGTTGATAATGCGATTCAACATACGGCGGCGAACGGTACCATTCGCTTAGGCTGGAAGGTTGATCAACAACGGTTG
TGCTGTTGGGTGAGTGATAATGGCGAAGGAATTGCCGAGGCCGATCTGCCCCATGTCTTTACCCCATTTTATCGAGGTGA
CCGCTCCCGTTCGCGCCGAACCGGTGGTACTGGCCTGGGACTCACGCTGGTGCAGAGCGTTGCCCACGCTCACGGTGGTG
AGGTTGCGATTTCGAGCCGGCAAGGCGAGGGGACAACAGTGACGATCATTCTGCCTCTCACACCACCACAGACAAATCAC
AGTAGAACTTAG

Upstream 100 bases:

>100_bases
GTTGAAGTACATATGAGCAATCTACGTGAAAAGATAGGTGATCATGAGCGCAAACTCATCCGTACCATCTATGGCGTCGG
CTACTGTTTACGGCCTGAAG

Downstream 100 bases:

>100_bases
AACATGTTATGTAAAGTTGAAATTGAGGATGAAAAGGTGCGAGAGCTGCATCCTATTCACCGTATCACTCTCGATCAGGT
GACTAACGCACTATCACGAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MKQQWHRLSLRQRLALLYSGLLALLLCLLGFGFYLDMRQFLFESTGLRIRAQAKPVIEQYLFEHPDPATQLPLIAEQLSR
DLTSRDTTALIFDQAGALLASGRRLPEEPPAQPVEASYVNMALAGHNNVNVIQDDGDQRMLSLLIPLRPAPGAPQVFGVV
QMSTPLSPIETTLQRQSIIIVSSIVIVLLAGSLIGYWLTSSTLRPLSDLIVACQKIAQGNLRQRVPVISPHDEIGKLTQA
FDEMVERLEQNFQAQRRFIADAAHEMRTPLTALRSGLEVLLRGAQDDPQTAFRLIQSMHRDVVRLCNVSEQLLDKARYES
GRSLNIQPVTMTDFLVEFTAQARLLAGERRVILESGPPIQAWIDGDSVKQALFHLVDNAIQHTAANGTIRLGWKVDQQRL
CCWVSDNGEGIAEADLPHVFTPFYRGDRSRSRRTGGTGLGLTLVQSVAHAHGGEVAISSRQGEGTTVTIILPLTPPQTNH
SRT

Sequences:

>Translated_483_residues
MKQQWHRLSLRQRLALLYSGLLALLLCLLGFGFYLDMRQFLFESTGLRIRAQAKPVIEQYLFEHPDPATQLPLIAEQLSR
DLTSRDTTALIFDQAGALLASGRRLPEEPPAQPVEASYVNMALAGHNNVNVIQDDGDQRMLSLLIPLRPAPGAPQVFGVV
QMSTPLSPIETTLQRQSIIIVSSIVIVLLAGSLIGYWLTSSTLRPLSDLIVACQKIAQGNLRQRVPVISPHDEIGKLTQA
FDEMVERLEQNFQAQRRFIADAAHEMRTPLTALRSGLEVLLRGAQDDPQTAFRLIQSMHRDVVRLCNVSEQLLDKARYES
GRSLNIQPVTMTDFLVEFTAQARLLAGERRVILESGPPIQAWIDGDSVKQALFHLVDNAIQHTAANGTIRLGWKVDQQRL
CCWVSDNGEGIAEADLPHVFTPFYRGDRSRSRRTGGTGLGLTLVQSVAHAHGGEVAISSRQGEGTTVTIILPLTPPQTNH
SRT
>Mature_483_residues
MKQQWHRLSLRQRLALLYSGLLALLLCLLGFGFYLDMRQFLFESTGLRIRAQAKPVIEQYLFEHPDPATQLPLIAEQLSR
DLTSRDTTALIFDQAGALLASGRRLPEEPPAQPVEASYVNMALAGHNNVNVIQDDGDQRMLSLLIPLRPAPGAPQVFGVV
QMSTPLSPIETTLQRQSIIIVSSIVIVLLAGSLIGYWLTSSTLRPLSDLIVACQKIAQGNLRQRVPVISPHDEIGKLTQA
FDEMVERLEQNFQAQRRFIADAAHEMRTPLTALRSGLEVLLRGAQDDPQTAFRLIQSMHRDVVRLCNVSEQLLDKARYES
GRSLNIQPVTMTDFLVEFTAQARLLAGERRVILESGPPIQAWIDGDSVKQALFHLVDNAIQHTAANGTIRLGWKVDQQRL
CCWVSDNGEGIAEADLPHVFTPFYRGDRSRSRRTGGTGLGLTLVQSVAHAHGGEVAISSRQGEGTTVTIILPLTPPQTNH
SRT

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=29.4545454545455, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=29.3040293040293, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1786783, Length=302, Percent_Identity=28.8079470198675, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=31.9148936170213, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790861, Length=339, Percent_Identity=26.2536873156342, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789808, Length=298, Percent_Identity=28.5234899328859, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787894, Length=266, Percent_Identity=28.9473684210526, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=262, Percent_Identity=29.0076335877863, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=331, Percent_Identity=26.5861027190332, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789149, Length=375, Percent_Identity=24.8, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790551, Length=295, Percent_Identity=30.1694915254237, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788279, Length=285, Percent_Identity=25.9649122807018, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789403, Length=305, Percent_Identity=25.9016393442623, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=26.8085106382979, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=326, Percent_Identity=26.3803680981595, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=22.5165562913907, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=26.8398268398268, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53467; Mature: 53467

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQWHRLSLRQRLALLYSGLLALLLCLLGFGFYLDMRQFLFESTGLRIRAQAKPVIEQY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
LFEHPDPATQLPLIAEQLSRDLTSRDTTALIFDQAGALLASGRRLPEEPPAQPVEASYVN
HHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHCCCCCCCCCCCCCCCHHHHE
MALAGHNNVNVIQDDGDQRMLSLLIPLRPAPGAPQVFGVVQMSTPLSPIETTLQRQSIII
EEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
VSSIVIVLLAGSLIGYWLTSSTLRPLSDLIVACQKIAQGNLRQRVPVISPHDEIGKLTQA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHH
FDEMVERLEQNFQAQRRFIADAAHEMRTPLTALRSGLEVLLRGAQDDPQTAFRLIQSMHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DVVRLCNVSEQLLDKARYESGRSLNIQPVTMTDFLVEFTAQARLLAGERRVILESGPPIQ
HHHHHHCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
AWIDGDSVKQALFHLVDNAIQHTAANGTIRLGWKVDQQRLCCWVSDNGEGIAEADLPHVF
EEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCHH
TPFYRGDRSRSRRTGGTGLGLTLVQSVAHAHGGEVAISSRQGEGTTVTIILPLTPPQTNH
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCC
SRT
CCC
>Mature Secondary Structure
MKQQWHRLSLRQRLALLYSGLLALLLCLLGFGFYLDMRQFLFESTGLRIRAQAKPVIEQY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
LFEHPDPATQLPLIAEQLSRDLTSRDTTALIFDQAGALLASGRRLPEEPPAQPVEASYVN
HHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHCCCCCCCCCCCCCCCHHHHE
MALAGHNNVNVIQDDGDQRMLSLLIPLRPAPGAPQVFGVVQMSTPLSPIETTLQRQSIII
EEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
VSSIVIVLLAGSLIGYWLTSSTLRPLSDLIVACQKIAQGNLRQRVPVISPHDEIGKLTQA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHH
FDEMVERLEQNFQAQRRFIADAAHEMRTPLTALRSGLEVLLRGAQDDPQTAFRLIQSMHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DVVRLCNVSEQLLDKARYESGRSLNIQPVTMTDFLVEFTAQARLLAGERRVILESGPPIQ
HHHHHHCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
AWIDGDSVKQALFHLVDNAIQHTAANGTIRLGWKVDQQRLCCWVSDNGEGIAEADLPHVF
EEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCHH
TPFYRGDRSRSRRTGGTGLGLTLVQSVAHAHGGEVAISSRQGEGTTVTIILPLTPPQTNH
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCC
SRT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]