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The map label for this gene is aroF [H]

Identifier: 222525375

GI number: 222525375

Start: 2694827

End: 2695882

Strand: Reverse

Name: aroF [H]

Synonym: Chy400_2120

Alternate gene names: 222525375

Gene position: 2695882-2694827 (Counterclockwise)

Preceding gene: 222525376

Following gene: 222525374

Centisome position: 51.17

GC content: 58.62

Gene sequence:

>1056_bases
ATGAACCAGACACCTTTAGCTAACCTGCACGTTCGCGAATTAACCCCTCTCCAACCACCGCGAGCGTTGAAAAACGAATT
ACCGATCACACCGGCGGCAGCGCATACGGTCGCTGAAACCCGTGCTGCTATTCGACGCATTTTACGCGGTGAAGACCAGC
GCCGCATCATGGTCGTTGGCCCGTGCTCGATCCACGATCCCGAAGCAGCCCTTGAATATGCCCGCCGTTTGCAGGCATTG
CAAAAGCCATTGGGCGATCAGTTGGTTATCGTAATGCGGGCCTACCTCGAAAAACCACGAACGACAGTAGGCTGGCGCGG
CCTGATTAACGACCCACACCTCGATGGTTCCTTTGATATGGCTGCCGGTCTCCGCATTGCCCGACAATTGCTGCTGGCGA
TCAATGAGCTAGGGGTACCGGTTGCGACCGAGATGCTCGATCCGATCAGCCCACAGTACCTCGACGATCAGATCAGCCTG
GCAACTATCGGTGCCCGCACGAGTGAAGCGCAGACTCATCGGGCGCTAGCCAGCGGTGTCTCGATGCCGGTCGGGTTCAA
AAATGGCACCGACGGCGGGATTCAGGTTGCCGTCAATGCCTGCGTTTCCGCCGCAGTACCGCACAGCTTTCTGGGCATCG
ATGAAGACGGGCGCAGTGCCGTCGTGCGCACAACCGGCAACCCCGATAGCTTTGTCATCTTGCGCGGTGGGCGGCATGGG
CCGAACTATCACCTGGAGTATATCGTCCAGACCACCCGCCTGATGCGTGAAGCCGAACGACAGCCCGCAGTGATGATTGA
CTGTAGTCATGCCAACTCCGGCAGTGATTTTCGCCGGCAGGAGGCCGTCTGGCAAACGGTGCTTGGGTATATGGTAGAGG
AACCATTGCCGATCATCGGCATGATGCTGGAGAGCAATCTCTTTGAGGGCAAGCAACCGCTGGTTGCCGACCGGAGTATG
CTCCGCTACGGCGTCTCGCTCACCGATGGCTGTGTGGGTTGGGACACCACCGAACGACTCTTGCACGAAGCACATCTGGC
CCTCTCGCGCAGGTAG

Upstream 100 bases:

>100_bases
TGACCTGCCGGTCAGCCGGACAGCAGCCGAATGAGGCAAGCCAACCCTTGACTCGCGTTATACTACCTGTAACGAGAACA
CATTGAGAACTGGCAACGGT

Downstream 100 bases:

>100_bases
ATGCAAGCGTTAAAGACCATGAGAGCGTACAGAAAAAGGCTGTCTTGAGCACGCCTTGAACAACCTCACCCCGGTCTCCC
TTCCAAGCTGCACGGGAGAG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNQTPLANLHVRELTPLQPPRALKNELPITPAAAHTVAETRAAIRRILRGEDQRRIMVVGPCSIHDPEAALEYARRLQAL
QKPLGDQLVIVMRAYLEKPRTTVGWRGLINDPHLDGSFDMAAGLRIARQLLLAINELGVPVATEMLDPISPQYLDDQISL
ATIGARTSEAQTHRALASGVSMPVGFKNGTDGGIQVAVNACVSAAVPHSFLGIDEDGRSAVVRTTGNPDSFVILRGGRHG
PNYHLEYIVQTTRLMREAERQPAVMIDCSHANSGSDFRRQEAVWQTVLGYMVEEPLPIIGMMLESNLFEGKQPLVADRSM
LRYGVSLTDGCVGWDTTERLLHEAHLALSRR

Sequences:

>Translated_351_residues
MNQTPLANLHVRELTPLQPPRALKNELPITPAAAHTVAETRAAIRRILRGEDQRRIMVVGPCSIHDPEAALEYARRLQAL
QKPLGDQLVIVMRAYLEKPRTTVGWRGLINDPHLDGSFDMAAGLRIARQLLLAINELGVPVATEMLDPISPQYLDDQISL
ATIGARTSEAQTHRALASGVSMPVGFKNGTDGGIQVAVNACVSAAVPHSFLGIDEDGRSAVVRTTGNPDSFVILRGGRHG
PNYHLEYIVQTTRLMREAERQPAVMIDCSHANSGSDFRRQEAVWQTVLGYMVEEPLPIIGMMLESNLFEGKQPLVADRSM
LRYGVSLTDGCVGWDTTERLLHEAHLALSRR
>Mature_351_residues
MNQTPLANLHVRELTPLQPPRALKNELPITPAAAHTVAETRAAIRRILRGEDQRRIMVVGPCSIHDPEAALEYARRLQAL
QKPLGDQLVIVMRAYLEKPRTTVGWRGLINDPHLDGSFDMAAGLRIARQLLLAINELGVPVATEMLDPISPQYLDDQISL
ATIGARTSEAQTHRALASGVSMPVGFKNGTDGGIQVAVNACVSAAVPHSFLGIDEDGRSAVVRTTGNPDSFVILRGGRHG
PNYHLEYIVQTTRLMREAERQPAVMIDCSHANSGSDFRRQEAVWQTVLGYMVEEPLPIIGMMLESNLFEGKQPLVADRSM
LRYGVSLTDGCVGWDTTERLLHEAHLALSRR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=349, Percent_Identity=51.8624641833811, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1786969, Length=344, Percent_Identity=52.0348837209302, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1787996, Length=351, Percent_Identity=45.014245014245, Blast_Score=303, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6320240, Length=343, Percent_Identity=46.9387755102041, Blast_Score=345, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6319726, Length=352, Percent_Identity=46.5909090909091, Blast_Score=330, Evalue=3e-91,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38564; Mature: 38564

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTPLANLHVRELTPLQPPRALKNELPITPAAAHTVAETRAAIRRILRGEDQRRIMVVG
CCCCCCCCEEHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
PCSIHDPEAALEYARRLQALQKPLGDQLVIVMRAYLEKPRTTVGWRGLINDPHLDGSFDM
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
AAGLRIARQLLLAINELGVPVATEMLDPISPQYLDDQISLATIGARTSEAQTHRALASGV
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCC
SMPVGFKNGTDGGIQVAVNACVSAAVPHSFLGIDEDGRSAVVRTTGNPDSFVILRGGRHG
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCC
PNYHLEYIVQTTRLMREAERQPAVMIDCSHANSGSDFRRQEAVWQTVLGYMVEEPLPIIG
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
MMLESNLFEGKQPLVADRSMLRYGVSLTDGCVGWDTTERLLHEAHLALSRR
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQTPLANLHVRELTPLQPPRALKNELPITPAAAHTVAETRAAIRRILRGEDQRRIMVVG
CCCCCCCCEEHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
PCSIHDPEAALEYARRLQALQKPLGDQLVIVMRAYLEKPRTTVGWRGLINDPHLDGSFDM
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
AAGLRIARQLLLAINELGVPVATEMLDPISPQYLDDQISLATIGARTSEAQTHRALASGV
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCC
SMPVGFKNGTDGGIQVAVNACVSAAVPHSFLGIDEDGRSAVVRTTGNPDSFVILRGGRHG
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCC
PNYHLEYIVQTTRLMREAERQPAVMIDCSHANSGSDFRRQEAVWQTVLGYMVEEPLPIIG
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
MMLESNLFEGKQPLVADRSMLRYGVSLTDGCVGWDTTERLLHEAHLALSRR
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]