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The map label for this gene is cheB1 [H]

Identifier: 222525073

GI number: 222525073

Start: 2288196

End: 2289281

Strand: Direct

Name: cheB1 [H]

Synonym: Chy400_1810

Alternate gene names: 222525073

Gene position: 2288196-2289281 (Clockwise)

Preceding gene: 222525072

Following gene: 222525074

Centisome position: 43.43

GC content: 58.66

Gene sequence:

>1086_bases
ATGACAAACCCTCTGCGCGTCCTTGTTGTCGATGACTCGGCGCTGATGCGTCGGTTGTTGCGGCAAATGCTTGAAAGTGA
TCCGACAATCCGCGTGGTCGGTGAGGCCGGTGATGGTAAGACGGCTATCGCGCTTACTGCTGAGCTGCGGCCTGATGTGA
TCACCCTCGATGTACGTATGCCGGTGCTCGATGGAGTCGAGACGACGCGCCAGATCATGGCGTACCATCCAACACCGATT
CTGGTTCTATCCGCAGCAGTCAGCGGTCAAGACGCCAACATCTCGTTTGAGGCGCTGGCTGCCGGTGCGCTTGAGGTGAT
GGAAAAGCCAAGCCTGACCGATCCTGACTCGCTCGATCACCTGCGGCGGGTGCTTATCAGACGGGTGAAGCTTATTGCGC
GGATCAAGGTCGTAACTCATCTACGCGGTCGTCGCCAGCCCCCACCTGTAGAACGTGTCTCTCTCGGTGATACGCCGCAC
TATGTGCGTACCCCGCGCATTGCCCCTGGTCAATTTCCGGTGCTGGTAATCGGCGCCTCGACCGGTGGGCCGAAAGTGGT
TCGTCAGTTATTAGCCGGTCTACCCCGTACCTTTGGGGCAGCGGTCATCGTAGTGCAGCACATTGCGCAGGGGTTCGGGG
CCGGAATGGCCGAATGGCTGGCCGGCGCAAGCGCACTTCCGCTGGAACTCGCTAGCGAGGGAATGCTGCTGCGACCCGGT
CATGCTATTCTGGCCCCTGATCGTGCCGATCTCCTTATCAAACCTGATGGCACTGTTCATCTGAGCATGTCACCGTTGTT
GCTCCAACGCCCTTCGATTGATATTACGATGACGGCAGTTGCCGAACTCTATGGAGCCAGTGCAGCAGGTGTACTATTGA
CCGGCATGGGGCGTGATGGGGCGGTTGGCATGCGGGCGATTCGACGGGCCGGTGGGCTGACGATTGCCCAGGACGAAGCC
AGTTGTACCATTTTTGGTATGCCTCGTGCGGCGATTGAGTTGGGTGCTGCCGAGCTGGTCTTGTCACCCGAAGAGATGAT
AGTGGTATTGAGCGAGCGTTTTGCCGGATCTGCGAGTATGCCATGA

Upstream 100 bases:

>100_bases
GACATTGATCTCCTCAACCTGCCTAATCGGGTGCGACTGGTACTGGATATGGAATAACAGGTTACCTTCGCTTAGCGGCG
CAATGATGGGGTAGGGGTGT

Downstream 100 bases:

>100_bases
CGCTATCTACAGAAGCTCTTGTTCCGCTTCGCGATTTGCTGGCGCGCTATTGTGGCGTCCTGCTCGATGATGCGCGTCTG
GTTACCCTCCGCAGTGCGGT

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTNPLRVLVVDDSALMRRLLRQMLESDPTIRVVGEAGDGKTAIALTAELRPDVITLDVRMPVLDGVETTRQIMAYHPTPI
LVLSAAVSGQDANISFEALAAGALEVMEKPSLTDPDSLDHLRRVLIRRVKLIARIKVVTHLRGRRQPPPVERVSLGDTPH
YVRTPRIAPGQFPVLVIGASTGGPKVVRQLLAGLPRTFGAAVIVVQHIAQGFGAGMAEWLAGASALPLELASEGMLLRPG
HAILAPDRADLLIKPDGTVHLSMSPLLLQRPSIDITMTAVAELYGASAAGVLLTGMGRDGAVGMRAIRRAGGLTIAQDEA
SCTIFGMPRAAIELGAAELVLSPEEMIVVLSERFAGSASMP

Sequences:

>Translated_361_residues
MTNPLRVLVVDDSALMRRLLRQMLESDPTIRVVGEAGDGKTAIALTAELRPDVITLDVRMPVLDGVETTRQIMAYHPTPI
LVLSAAVSGQDANISFEALAAGALEVMEKPSLTDPDSLDHLRRVLIRRVKLIARIKVVTHLRGRRQPPPVERVSLGDTPH
YVRTPRIAPGQFPVLVIGASTGGPKVVRQLLAGLPRTFGAAVIVVQHIAQGFGAGMAEWLAGASALPLELASEGMLLRPG
HAILAPDRADLLIKPDGTVHLSMSPLLLQRPSIDITMTAVAELYGASAAGVLLTGMGRDGAVGMRAIRRAGGLTIAQDEA
SCTIFGMPRAAIELGAAELVLSPEEMIVVLSERFAGSASMP
>Mature_360_residues
TNPLRVLVVDDSALMRRLLRQMLESDPTIRVVGEAGDGKTAIALTAELRPDVITLDVRMPVLDGVETTRQIMAYHPTPIL
VLSAAVSGQDANISFEALAAGALEVMEKPSLTDPDSLDHLRRVLIRRVKLIARIKVVTHLRGRRQPPPVERVSLGDTPHY
VRTPRIAPGQFPVLVIGASTGGPKVVRQLLAGLPRTFGAAVIVVQHIAQGFGAGMAEWLAGASALPLELASEGMLLRPGH
AILAPDRADLLIKPDGTVHLSMSPLLLQRPSIDITMTAVAELYGASAAGVLLTGMGRDGAVGMRAIRRAGGLTIAQDEAS
CTIFGMPRAAIELGAAELVLSPEEMIVVLSERFAGSASMP

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=335, Percent_Identity=34.6268656716418, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788550, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788521, Length=116, Percent_Identity=40.5172413793103, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38247; Mature: 38116

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPLRVLVVDDSALMRRLLRQMLESDPTIRVVGEAGDGKTAIALTAELRPDVITLDVRM
CCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEC
PVLDGVETTRQIMAYHPTPILVLSAAVSGQDANISFEALAAGALEVMEKPSLTDPDSLDH
CCCCCHHHHHHHHEECCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHH
LRRVLIRRVKLIARIKVVTHLRGRRQPPPVERVSLGDTPHYVRTPRIAPGQFPVLVIGAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCCCCCCCCCEEEEECC
TGGPKVVRQLLAGLPRTFGAAVIVVQHIAQGFGAGMAEWLAGASALPLELASEGMLLRPG
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHCCCEEECCC
HAILAPDRADLLIKPDGTVHLSMSPLLLQRPSIDITMTAVAELYGASAAGVLLTGMGRDG
CEEECCCCCCEEECCCCEEEEECCCCEEECCCCCEEHHHHHHHHCCCCCCEEEEECCCCC
AVGMRAIRRAGGLTIAQDEASCTIFGMPRAAIELGAAELVLSPEEMIVVLSERFAGSASM
HHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHCCCHHEEECHHHHEEEEEHHCCCCCCC
P
C
>Mature Secondary Structure 
TNPLRVLVVDDSALMRRLLRQMLESDPTIRVVGEAGDGKTAIALTAELRPDVITLDVRM
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEC
PVLDGVETTRQIMAYHPTPILVLSAAVSGQDANISFEALAAGALEVMEKPSLTDPDSLDH
CCCCCHHHHHHHHEECCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHH
LRRVLIRRVKLIARIKVVTHLRGRRQPPPVERVSLGDTPHYVRTPRIAPGQFPVLVIGAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCCCCCCCCCEEEEECC
TGGPKVVRQLLAGLPRTFGAAVIVVQHIAQGFGAGMAEWLAGASALPLELASEGMLLRPG
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHCCCEEECCC
HAILAPDRADLLIKPDGTVHLSMSPLLLQRPSIDITMTAVAELYGASAAGVLLTGMGRDG
CEEECCCCCCEEECCCCEEEEECCCCEEECCCCCEEHHHHHHHHCCCCCCEEEEECCCCC
AVGMRAIRRAGGLTIAQDEASCTIFGMPRAAIELGAAELVLSPEEMIVVLSERFAGSASM
HHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHCCCHHEEECHHHHEEEEEHHCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA