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The map label for this gene is yitJ [H]

Identifier: 222524853

GI number: 222524853

Start: 2010069

End: 2010992

Strand: Reverse

Name: yitJ [H]

Synonym: Chy400_1580

Alternate gene names: 222524853

Gene position: 2010992-2010069 (Counterclockwise)

Preceding gene: 222524854

Following gene: 222524852

Centisome position: 38.17

GC content: 58.44

Gene sequence:

>924_bases
ATGCATTCTACCCTTCAGCGCCGGCTCGCTGCCGGCCAGATTGTCGTTACCGGCGAGATTGCACCGCCAAAGGGGGCGGC
ACGTAGCCATCTCGAAGCATTGGCCCGCAACATTCGCGATTATGTCGATGCGGTCAATTTGACCGACAACCAGCGCGGTA
TTGCCCGCATGTCGTCGCTGGGTGGGAGTGTCATTTTGCAACAACTCGGCATTGAGCCGATCATGCAGATGACCTGCCAG
CATCGCAATCGGATTGCCCTGCAAGCCGATGCGCTCAGTGCAGCGGCCCTTGGTGTTCGTAATTTACTGGCAATGACGGG
TGACCATCCCCGGATTGGCGACCATCCAGAGGCCAAAAATGTCCTCGATCTCAATTCATTCCAACTGATCCGGGTCTTAC
GCACGCTACGCGATCAGGCGACGTTCCAATCCGGTACGCCGCTCAAAGAGGCGCCACGATTCTTTATCGGCAGCGTCGCG
AACCCCAATGTTGAACGGGCTGCCCGCCTTGAGAAAAAGATCGAGGCCGGTGCCGAATTTGTCCAAACGCAACTCATCTT
CGATGTCGGGCGATTCCGGCAGTGGATGGCCGATGTACGCGCAGCCGGTTTACACCAACAGGCGTATATTCTGGCCGGCG
TGATGATCTTGCGTCGACCGCACTCGGCCATCTACCTGCGCGATCACCTGCCCGGTACCCTTATGCCGGAGACGGTGATT
GAGCGAATGCAGCGGGCTACCGACAGCGAAGCGGAAGGGATCACCCTGGCTGCCGAACTGGTCAACGAGCTACTCAGCGT
AGAAGGTGTGGCCGGCGTTCACATTATGTCGGTTGACTGGACGCGGGCGATTCCACGGGTCGTGGAACAGGCCGGTCTGT
TACCCCGGCCACCGGTACCGTCAACCGAAGAGAATGTGCTATAA

Upstream 100 bases:

>100_bases
GGTGGGTATTCGCGACAACCTCATCCGCCTTTCGTGCGGGATTGAGGATGTGAGTGACTTGATCGCCGATCTGCAACAGG
CTCTTGCCGACGAATAACCT

Downstream 100 bases:

>100_bases
CATATGTAGTACATGCTGATCGATGAAAGTACCACTATGGCTATCATTTTAAAATCTCCTGCCCAGATAGAACTCCTACG
TGCTGCCGGTCAACTGGTGC

Product: methylenetetrahydrofolate reductase

Products: NA

Alternate protein names: Homocysteine S-methyltransferase; S-methylmethionine:homocysteine methyltransferase; 5,10-methylenetetrahydrofolate reductase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSLGGSVILQQLGIEPIMQMTCQ
HRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKNVLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVA
NPNVERAARLEKKIEAGAEFVQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVPSTEENVL

Sequences:

>Translated_307_residues
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSLGGSVILQQLGIEPIMQMTCQ
HRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKNVLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVA
NPNVERAARLEKKIEAGAEFVQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVPSTEENVL
>Mature_307_residues
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSLGGSVILQQLGIEPIMQMTCQ
HRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKNVLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVA
NPNVERAARLEKKIEAGAEFVQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVPSTEENVL

Specific function: Unknown

COG id: COG0685

COG function: function code E; 5,10-methylenetetrahydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Hcy-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003171
- InterPro:   IPR003726 [H]

Pfam domain/function: PF02219 MTHFR; PF02574 S-methyl_trans [H]

EC number: =2.1.1.10; =1.5.1.20 [H]

Molecular weight: Translated: 33692; Mature: 33692

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSL
CCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GGSVILQQLGIEPIMQMTCQHRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKN
CHHHHHHHHCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVP
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCC
STEENVL
CCCCCCC
>Mature Secondary Structure
MHSTLQRRLAAGQIVVTGEIAPPKGAARSHLEALARNIRDYVDAVNLTDNQRGIARMSSL
CCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GGSVILQQLGIEPIMQMTCQHRNRIALQADALSAAALGVRNLLAMTGDHPRIGDHPEAKN
CHHHHHHHHCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VLDLNSFQLIRVLRTLRDQATFQSGTPLKEAPRFFIGSVANPNVERAARLEKKIEAGAEF
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VQTQLIFDVGRFRQWMADVRAAGLHQQAYILAGVMILRRPHSAIYLRDHLPGTLMPETVI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
ERMQRATDSEAEGITLAAELVNELLSVEGVAGVHIMSVDWTRAIPRVVEQAGLLPRPPVP
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCC
STEENVL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]