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The map label for this gene is dppB [H]

Identifier: 222524401

GI number: 222524401

Start: 1423294

End: 1424298

Strand: Direct

Name: dppB [H]

Synonym: Chy400_1125

Alternate gene names: 222524401

Gene position: 1423294-1424298 (Clockwise)

Preceding gene: 222524400

Following gene: 222524402

Centisome position: 27.01

GC content: 51.64

Gene sequence:

>1005_bases
ATGACAGCCTATATCATTCGGCGCATTCTGTGGAATATCCCCGTTCTCATCATTGTTGGCTTTATTACCTTCGGTATTGC
CAAGCTAACACCGGGTGGGCCATTCGATACCCAACCTGAACGGCGGCAGCTCTCGCCGCGGGTTGAAGCAATTTTGCGTG
AGCGCTTTGGGATGGATTTGCCGTTCTGGCGGCAGTTTACCCGCTATATGTTTTTTGATATTGTGCCCGATACGCGCACC
GGTGAATGGAAGATTCAATGGGGTGCCATTGCCGGGAATCTCGGCCCAACCTACGCTTCACGCGGAGCGCGGACGGTACA
GCAGGAATTGTTTGAAGGCACACCATCCCGACCGAGTAAGTTTTATTATTCGGCACGTCTGGGGTTGCAGGCACTGGCCT
TTGCCGTTGTGTTTGGCATTCCGCTTGGTATCCTGGCAGCATTACGACAAAATACCTGGCTTGATTATCTGCTCTCACTC
TCATCAACCATCTTTGTTGCGTTGGGAACACTGATTACCAGTCTGATTCTGGTCATTATCTTTGCCGTCATCCTCAACTG
GTTTACGGTTATTCCAGACTGGAATGATCCGATCAAGCCGTGGGTCTTGCCAACCGTCGCGCTTGGTTCGACCAGCATGG
CATTCATTGCCCGCCTGACGCGGGCCAGCGTGCTGGAAGTGAAGCGTCAGGACTATATTCGCACTGCGCAGGCAAAAGGA
CTGGCCGGCCACGTGATTATCTGGCGTCATATGCTGAAAAATTCGTTACTGCCGGTGGTGACTATTCTGGGGCCGGCGCT
GGCCGGTTTGATTACCGGTACCCTGTTTGTTGAAACTATCTTTCAGGTTCCCGGTATGGGTCGCACCTTCGTTGACGCCA
TCGGTAAGCGTGACTATTCGATGATTATGGCCGGATCGCTCATCTATGTCTTTTTCCTGGGCATTGCCAATTTACTGGTC
GATATTGCTTACGGTATTCTTGATCCACGTATTACCTACAAGTAG

Upstream 100 bases:

>100_bases
CTTCTTCAACCTGCCCAACGTTGATGTCCAACCATAGTCGGCGTTCCTGAAGCCCTATCGGTGGCGCGAGATAACCTGCT
CGCGCCACCAGAGCATGCCT

Downstream 100 bases:

>100_bases
TGAGGAACAGTGTGACTTCATCGGCCAGACCACTGACAAATCCTATCGACCTTCAGAACTTAAATACGAAACCGCGTAGC
TTGTGGTCAGATGCACTACG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTAYIIRRILWNIPVLIIVGFITFGIAKLTPGGPFDTQPERRQLSPRVEAILRERFGMDLPFWRQFTRYMFFDIVPDTRT
GEWKIQWGAIAGNLGPTYASRGARTVQQELFEGTPSRPSKFYYSARLGLQALAFAVVFGIPLGILAALRQNTWLDYLLSL
SSTIFVALGTLITSLILVIIFAVILNWFTVIPDWNDPIKPWVLPTVALGSTSMAFIARLTRASVLEVKRQDYIRTAQAKG
LAGHVIIWRHMLKNSLLPVVTILGPALAGLITGTLFVETIFQVPGMGRTFVDAIGKRDYSMIMAGSLIYVFFLGIANLLV
DIAYGILDPRITYK

Sequences:

>Translated_334_residues
MTAYIIRRILWNIPVLIIVGFITFGIAKLTPGGPFDTQPERRQLSPRVEAILRERFGMDLPFWRQFTRYMFFDIVPDTRT
GEWKIQWGAIAGNLGPTYASRGARTVQQELFEGTPSRPSKFYYSARLGLQALAFAVVFGIPLGILAALRQNTWLDYLLSL
SSTIFVALGTLITSLILVIIFAVILNWFTVIPDWNDPIKPWVLPTVALGSTSMAFIARLTRASVLEVKRQDYIRTAQAKG
LAGHVIIWRHMLKNSLLPVVTILGPALAGLITGTLFVETIFQVPGMGRTFVDAIGKRDYSMIMAGSLIYVFFLGIANLLV
DIAYGILDPRITYK
>Mature_333_residues
TAYIIRRILWNIPVLIIVGFITFGIAKLTPGGPFDTQPERRQLSPRVEAILRERFGMDLPFWRQFTRYMFFDIVPDTRTG
EWKIQWGAIAGNLGPTYASRGARTVQQELFEGTPSRPSKFYYSARLGLQALAFAVVFGIPLGILAALRQNTWLDYLLSLS
STIFVALGTLITSLILVIIFAVILNWFTVIPDWNDPIKPWVLPTVALGSTSMAFIARLTRASVLEVKRQDYIRTAQAKGL
AGHVIIWRHMLKNSLLPVVTILGPALAGLITGTLFVETIFQVPGMGRTFVDAIGKRDYSMIMAGSLIYVFFLGIANLLVD
IAYGILDPRITYK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=35.1190476190476, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789965, Length=363, Percent_Identity=31.404958677686, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=31.6568047337278, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=31.044776119403, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787761, Length=356, Percent_Identity=31.7415730337079, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787550, Length=260, Percent_Identity=26.1538461538462, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788504, Length=393, Percent_Identity=25.9541984732824, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37362; Mature: 37231

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYIIRRILWNIPVLIIVGFITFGIAKLTPGGPFDTQPERRQLSPRVEAILRERFGMDL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCC
PFWRQFTRYMFFDIVPDTRTGEWKIQWGAIAGNLGPTYASRGARTVQQELFEGTPSRPSK
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHH
FYYSARLGLQALAFAVVFGIPLGILAALRQNTWLDYLLSLSSTIFVALGTLITSLILVII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAVILNWFTVIPDWNDPIKPWVLPTVALGSTSMAFIARLTRASVLEVKRQDYIRTAQAKG
HHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LAGHVIIWRHMLKNSLLPVVTILGPALAGLITGTLFVETIFQVPGMGRTFVDAIGKRDYS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHH
MIMAGSLIYVFFLGIANLLVDIAYGILDPRITYK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAYIIRRILWNIPVLIIVGFITFGIAKLTPGGPFDTQPERRQLSPRVEAILRERFGMDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCC
PFWRQFTRYMFFDIVPDTRTGEWKIQWGAIAGNLGPTYASRGARTVQQELFEGTPSRPSK
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHH
FYYSARLGLQALAFAVVFGIPLGILAALRQNTWLDYLLSLSSTIFVALGTLITSLILVII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAVILNWFTVIPDWNDPIKPWVLPTVALGSTSMAFIARLTRASVLEVKRQDYIRTAQAKG
HHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LAGHVIIWRHMLKNSLLPVVTILGPALAGLITGTLFVETIFQVPGMGRTFVDAIGKRDYS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHH
MIMAGSLIYVFFLGIANLLVDIAYGILDPRITYK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]