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The map label for this gene is fruK [H]

Identifier: 222524152

GI number: 222524152

Start: 1098914

End: 1099882

Strand: Direct

Name: fruK [H]

Synonym: Chy400_0868

Alternate gene names: 222524152

Gene position: 1098914-1099882 (Clockwise)

Preceding gene: 222524151

Following gene: 222524153

Centisome position: 20.86

GC content: 57.38

Gene sequence:

>969_bases
ATGAACATCGCTACCATAACCCTCAATCCGGCCATTGATCAGACGGTCTTCGTCGATCATTTTCAATTGAACACCGTGAA
CCGGGCACGCGCTATGCAACGCGATGCCGGCGGCAAAGGGGTGAATGTCGCATCCTTCCTGGCCGATTATGGCCTTTCGG
TCACCGCCACCGGCTTACTCGGTGCCGAAAATCCCCATATCTTTGAGCGCCATTTTGCGGCCAAAGGCATCACCGACCGG
TTTGTCCGGGTGCCGGGTGCCACCCGGATCGGGGTAAAAATCGTTGATGAAGCGAACCAGCAGACGACCGATATTAATCT
CCCTGGTTTGCCGCCACCACCCGCTGCCTTGAACACCCTGATCGACGTGATCGATGAGCTGGCCGTTAATCACGAATGGT
TTGTGCTGGCCGGCAAGTTACCGCCCGGCGTACCGATTGAATTCATTCCCAACCTGGTTGCCCGTCTCCGCAGTTTTAAC
TGCAACGTTGCCCTTGATGTCAGCGGGCCGGCCCTGATTGCCGGTCTGCAAGCCCAACCTTCACTGGTGAAACCCAACCT
TGATGAGCTACGCCAGATCGATCTGCTCGATGGTGAAGGGTTGGAAGCAGTGGGCAATGCGGCGCGTCGGATCAATCAGA
TGGGAGTAGGGCTGGCAATTGTATCTATGGGTGCGCAGGGTGCAATCTTTAGCGATGGAACGCAATTACTGCACGCCATC
CCGCCATCGGTCACCGTGCGGAGTACAGTCGGTGCCGGGGATGCAATGGTCGCCGGCACCATTGCCGGCCTCGTTGAAGG
ACTATCGCTAACCGAGATCGCTCGTCGCGCAACAGCCTTTTCACTGGCAGCGCTCGGTTCAATTGGGGCACACCTGCCGC
CACGCGCTGAACTGATCGCGCTGGCAGCAAAAGTTACCGTTACCGTGGTTGATCCGGCTGTCACGACCGTGACGCCTGTT
GATCAATAG

Upstream 100 bases:

>100_bases
CGACCATCAAAGCGCACCTGCGCGGTCTGAGTGCCGCCGATCTGCGTGATCTGGCGCGACGAGCACTGGCGTGTCGTAAT
GCAGCGGAGGTGCGCGCACT

Downstream 100 bases:

>100_bases
AAGTTGTAAGGAGCAAAGGGAGGAGAACCATGGCGGTCATTGTCGCAATTACGTCATGTCCCACCGGTATCGCGCATACC
TTTATGGCAGCGGAGGGGCT

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNIATITLNPAIDQTVFVDHFQLNTVNRARAMQRDAGGKGVNVASFLADYGLSVTATGLLGAENPHIFERHFAAKGITDR
FVRVPGATRIGVKIVDEANQQTTDINLPGLPPPPAALNTLIDVIDELAVNHEWFVLAGKLPPGVPIEFIPNLVARLRSFN
CNVALDVSGPALIAGLQAQPSLVKPNLDELRQIDLLDGEGLEAVGNAARRINQMGVGLAIVSMGAQGAIFSDGTQLLHAI
PPSVTVRSTVGAGDAMVAGTIAGLVEGLSLTEIARRATAFSLAALGSIGAHLPPRAELIALAAKVTVTVVDPAVTTVTPV
DQ

Sequences:

>Translated_322_residues
MNIATITLNPAIDQTVFVDHFQLNTVNRARAMQRDAGGKGVNVASFLADYGLSVTATGLLGAENPHIFERHFAAKGITDR
FVRVPGATRIGVKIVDEANQQTTDINLPGLPPPPAALNTLIDVIDELAVNHEWFVLAGKLPPGVPIEFIPNLVARLRSFN
CNVALDVSGPALIAGLQAQPSLVKPNLDELRQIDLLDGEGLEAVGNAARRINQMGVGLAIVSMGAQGAIFSDGTQLLHAI
PPSVTVRSTVGAGDAMVAGTIAGLVEGLSLTEIARRATAFSLAALGSIGAHLPPRAELIALAAKVTVTVVDPAVTTVTPV
DQ
>Mature_322_residues
MNIATITLNPAIDQTVFVDHFQLNTVNRARAMQRDAGGKGVNVASFLADYGLSVTATGLLGAENPHIFERHFAAKGITDR
FVRVPGATRIGVKIVDEANQQTTDINLPGLPPPPAALNTLIDVIDELAVNHEWFVLAGKLPPGVPIEFIPNLVARLRSFN
CNVALDVSGPALIAGLQAQPSLVKPNLDELRQIDLLDGEGLEAVGNAARRINQMGVGLAIVSMGAQGAIFSDGTQLLHAI
PPSVTVRSTVGAGDAMVAGTIAGLVEGLSLTEIARRATAFSLAALGSIGAHLPPRAELIALAAKVTVTVVDPAVTTVTPV
DQ

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=307, Percent_Identity=37.785016286645, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788017, Length=298, Percent_Identity=30.8724832214765, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33518; Mature: 33518

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIATITLNPAIDQTVFVDHFQLNTVNRARAMQRDAGGKGVNVASFLADYGLSVTATGLL
CEEEEEEECCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEE
GAENPHIFERHFAAKGITDRFVRVPGATRIGVKIVDEANQQTTDINLPGLPPPPAALNTL
CCCCCCHHHHHHHHCCCCHHEEECCCCCEECEEEEECCCCCEEEEECCCCCCCHHHHHHH
IDVIDELAVNHEWFVLAGKLPPGVPIEFIPNLVARLRSFNCNVALDVSGPALIAGLQAQP
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCC
SLVKPNLDELRQIDLLDGEGLEAVGNAARRINQMGVGLAIVSMGAQGAIFSDGTQLLHAI
CCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCHHHHHHC
PPSVTVRSTVGAGDAMVAGTIAGLVEGLSLTEIARRATAFSLAALGSIGAHLPPRAELIA
CCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHE
LAAKVTVTVVDPAVTTVTPVDQ
EEEEEEEEEECCCEEEECCCCC
>Mature Secondary Structure
MNIATITLNPAIDQTVFVDHFQLNTVNRARAMQRDAGGKGVNVASFLADYGLSVTATGLL
CEEEEEEECCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEE
GAENPHIFERHFAAKGITDRFVRVPGATRIGVKIVDEANQQTTDINLPGLPPPPAALNTL
CCCCCCHHHHHHHHCCCCHHEEECCCCCEECEEEEECCCCCEEEEECCCCCCCHHHHHHH
IDVIDELAVNHEWFVLAGKLPPGVPIEFIPNLVARLRSFNCNVALDVSGPALIAGLQAQP
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCC
SLVKPNLDELRQIDLLDGEGLEAVGNAARRINQMGVGLAIVSMGAQGAIFSDGTQLLHAI
CCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCHHHHHHC
PPSVTVRSTVGAGDAMVAGTIAGLVEGLSLTEIARRATAFSLAALGSIGAHLPPRAELIA
CCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHE
LAAKVTVTVVDPAVTTVTPVDQ
EEEEEEEEEECCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850730; 2254279 [H]