Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 222523654

GI number: 222523654

Start: 424774

End: 425808

Strand: Direct

Name: argC [H]

Synonym: Chy400_0360

Alternate gene names: 222523654

Gene position: 424774-425808 (Clockwise)

Preceding gene: 222523653

Following gene: 222523659

Centisome position: 8.06

GC content: 59.61

Gene sequence:

>1035_bases
ATGAGCTTACGAGTCAGCATTGTGGGGGCAAGCGGTTATGTCGGCGGAGAACTCCTCCGCCTCCTGCTCGATCATCCCCA
CGTATCAATCATACAGGCTACCAGTGCCCGCAATGCAGGACGGTATCTCTACCAGGTACATCCCAACCTGCGCGGACGCA
CCAACCTGCAATTCGTCCACCCTGACACCCTGCAGCCGTGTGATGTGCTCTTCCTGGCCCTCCCACACGGCGAAGCAGCT
CAGGCTATTGAACGCTACGCCAGCCTGGCCGAACGGATCATCGACTGTTCAGCCGATTTTCGCCTGCGCGATCCGGCAGT
GTACCAGCAATGGTACGGGAGCGCTCACCCGGCTCCGGCATGGCTCGAACGCTTCGTGTATGGGCTGCCCGAAGTTAATC
GGGCGGCGCTGACCGGTGCTCGCTACGCCAGTGGGGTTGGCTGCAACGCCACAGCCACCAACCTTGCCCTGTTGCCACTG
GTTGAAGCGAACCTGATCGACCGCAGTCGCCCGATCATTGCCGACGTGAAAGTCGGCTCATCGGAAGGTGGGGCCACCGT
TAACGAAGCCAGTCACCACCCCGAACGGTCTGGTGCGGTACGCTCCTTTGCGCCGGTGGGACATCGCCACCTCGCCGAAG
TCGAGCAAGTGACCGGCCTGCGCAATGTGCATCTCTCAATTACTGCCATTGAGCTAGTGCGTGGCGCACTGGCAACAGTT
CACGCTTTCGCCAGTCGCGAACTGAGCGAGAAGGAACTCTGGCAGGCCTACCGGACATTTGCCCGCGAACAGCCGTTCAT
TCGTATCGTCAAAGAGCGGCAGGGCATTTACCGCTATCCAGAACCAAAGATTCTGGCCGGCACCAACTACGCCGACATCG
GCTTCGCGTATGAACCGGCGACCGGGCGGATTGTGAGTATCTGTGCTATCGACAACCTGATGAAGGGTGCTGCCGGCAGT
GCCGTGCAATGTATGAACCTGATGTGCGGCTTTGCGGAGACGACAGCCTTGACATTTGCCGGTTTACATCCGTAA

Upstream 100 bases:

>100_bases
ACGAAGAGCGAATGTCTGCTGACGGCCAGACTCCGACGGATTACAACCTGTTTGCAGGACTACCACCCAGCAGAGTTGGC
CGTTGTACGCAAGGTGTTGT

Downstream 100 bases:

>100_bases
GGCGGAGGACAGCAGAGCGAAGCTGTATCTGAACTCATAGCTGTAGCCATTACCGGGCAAGAGACACAGAAAAGGGCGCA
CCGTTGTGCGCCCTCAACAA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSLRVSIVGASGYVGGELLRLLLDHPHVSIIQATSARNAGRYLYQVHPNLRGRTNLQFVHPDTLQPCDVLFLALPHGEAA
QAIERYASLAERIIDCSADFRLRDPAVYQQWYGSAHPAPAWLERFVYGLPEVNRAALTGARYASGVGCNATATNLALLPL
VEANLIDRSRPIIADVKVGSSEGGATVNEASHHPERSGAVRSFAPVGHRHLAEVEQVTGLRNVHLSITAIELVRGALATV
HAFASRELSEKELWQAYRTFAREQPFIRIVKERQGIYRYPEPKILAGTNYADIGFAYEPATGRIVSICAIDNLMKGAAGS
AVQCMNLMCGFAETTALTFAGLHP

Sequences:

>Translated_344_residues
MSLRVSIVGASGYVGGELLRLLLDHPHVSIIQATSARNAGRYLYQVHPNLRGRTNLQFVHPDTLQPCDVLFLALPHGEAA
QAIERYASLAERIIDCSADFRLRDPAVYQQWYGSAHPAPAWLERFVYGLPEVNRAALTGARYASGVGCNATATNLALLPL
VEANLIDRSRPIIADVKVGSSEGGATVNEASHHPERSGAVRSFAPVGHRHLAEVEQVTGLRNVHLSITAIELVRGALATV
HAFASRELSEKELWQAYRTFAREQPFIRIVKERQGIYRYPEPKILAGTNYADIGFAYEPATGRIVSICAIDNLMKGAAGS
AVQCMNLMCGFAETTALTFAGLHP
>Mature_343_residues
SLRVSIVGASGYVGGELLRLLLDHPHVSIIQATSARNAGRYLYQVHPNLRGRTNLQFVHPDTLQPCDVLFLALPHGEAAQ
AIERYASLAERIIDCSADFRLRDPAVYQQWYGSAHPAPAWLERFVYGLPEVNRAALTGARYASGVGCNATATNLALLPLV
EANLIDRSRPIIADVKVGSSEGGATVNEASHHPERSGAVRSFAPVGHRHLAEVEQVTGLRNVHLSITAIELVRGALATVH
AFASRELSEKELWQAYRTFAREQPFIRIVKERQGIYRYPEPKILAGTNYADIGFAYEPATGRIVSICAIDNLMKGAAGSA
VQCMNLMCGFAETTALTFAGLHP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=348, Percent_Identity=30.4597701149425, Blast_Score=137, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6320913, Length=338, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37448; Mature: 37317

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRVSIVGASGYVGGELLRLLLDHPHVSIIQATSARNAGRYLYQVHPNLRGRTNLQFVH
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEC
PDTLQPCDVLFLALPHGEAAQAIERYASLAERIIDCSADFRLRDPAVYQQWYGSAHPAPA
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHCCCCCCCHH
WLERFVYGLPEVNRAALTGARYASGVGCNATATNLALLPLVEANLIDRSRPIIADVKVGS
HHHHHHHCCCCCCHHHHCCCHHHCCCCCCCCHHCEEEEHHHHHHHHCCCCCEEEEEEECC
SEGGATVNEASHHPERSGAVRSFAPVGHRHLAEVEQVTGLRNVHLSITAIELVRGALATV
CCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
HAFASRELSEKELWQAYRTFAREQPFIRIVKERQGIYRYPEPKILAGTNYADIGFAYEPA
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEECCC
TGRIVSICAIDNLMKGAAGSAVQCMNLMCGFAETTALTFAGLHP
CCCEEEEEHHHHHHHCCCCCHHHHHHHHHCCHHHHHEEEECCCC
>Mature Secondary Structure 
SLRVSIVGASGYVGGELLRLLLDHPHVSIIQATSARNAGRYLYQVHPNLRGRTNLQFVH
CEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEC
PDTLQPCDVLFLALPHGEAAQAIERYASLAERIIDCSADFRLRDPAVYQQWYGSAHPAPA
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHCCCCCCCHH
WLERFVYGLPEVNRAALTGARYASGVGCNATATNLALLPLVEANLIDRSRPIIADVKVGS
HHHHHHHCCCCCCHHHHCCCHHHCCCCCCCCHHCEEEEHHHHHHHHCCCCCEEEEEEECC
SEGGATVNEASHHPERSGAVRSFAPVGHRHLAEVEQVTGLRNVHLSITAIELVRGALATV
CCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
HAFASRELSEKELWQAYRTFAREQPFIRIVKERQGIYRYPEPKILAGTNYADIGFAYEPA
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEECCC
TGRIVSICAIDNLMKGAAGSAVQCMNLMCGFAETTALTFAGLHP
CCCEEEEEHHHHHHHCCCCCHHHHHHHHHCCHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA