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The map label for this gene is dck [H]

Identifier: 222152095

GI number: 222152095

Start: 1984322

End: 1984978

Strand: Direct

Name: dck [H]

Synonym: MCCL_1852

Alternate gene names: 222152095

Gene position: 1984322-1984978 (Clockwise)

Preceding gene: 222152094

Following gene: 222152101

Centisome position: 94.39

GC content: 38.36

Gene sequence:

>657_bases
ATGTATACAATCCCTAATGATGCAATCATCACTATCGCTGGTACTGTCGGAGTCGGAAAAAGTTCGTTAACAAAAGCACT
GGCTGAGAAGCTGAACTTCAGAACTTCTTTTGAAAAAGTAGATAACAATCCTTACTTAGAAAAATTCTACAATGATTTTG
ATCGCTGGAGCTTTCATTTACAAATCTATTTTCTTGCAGAACGTTTTAAAGAACAAAAACGCATGTTTGAATATGGCGGC
GGTTTTATTCAGGACCGCTCAATCTATGAAGATGTAGATATCTTTGCTAAGATGCATGAAGAAGGCGGCACGATGACGAA
AGAAGACTTCGCAACTTATTATCAGTTATACGAAGCAATGGTAATGACGCCATATTTCCCGCAACCCGACTGTTTAATCT
TCTTAGAAAGCGATTATGAAGATGTGATCAATCGTATCGCGGAACGTGGTCGTCAAATGGAAATCGAAACAGATGAAGCT
TATTGGCGTGCATTATACGCACGTTACGTCGAATGGATTGAAAACTTCAATGCGTGCCCTGTCGTAAGAATTAATATCAA
TGAATATGATGTATATGGTGATATCGATTCACTTGATCCAGTGATCGAGAAGATTGCTAAAGTGATCCACACACATCGTG
CAATCCATAAAAGATAA

Upstream 100 bases:

>100_bases
CAGACGTTACTTATCGATACAAGCGATATGGACTTTGTAAACAATGCCGCAGATTATGAGCATATCGTACAACAAATAAA
AGATATTATAGGAGCTTAAT

Downstream 100 bases:

>100_bases
ATATAAAAATGGTACGGAACATTACCGTACCATTTTTATATTGGTTTATAACCCTAATTTATCAATCATCTCTGCAACAC
TATTTAATACTATATCCGCA

Product: deoxyadenosine kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MYTIPNDAIITIAGTVGVGKSSLTKALAEKLNFRTSFEKVDNNPYLEKFYNDFDRWSFHLQIYFLAERFKEQKRMFEYGG
GFIQDRSIYEDVDIFAKMHEEGGTMTKEDFATYYQLYEAMVMTPYFPQPDCLIFLESDYEDVINRIAERGRQMEIETDEA
YWRALYARYVEWIENFNACPVVRININEYDVYGDIDSLDPVIEKIAKVIHTHRAIHKR

Sequences:

>Translated_218_residues
MYTIPNDAIITIAGTVGVGKSSLTKALAEKLNFRTSFEKVDNNPYLEKFYNDFDRWSFHLQIYFLAERFKEQKRMFEYGG
GFIQDRSIYEDVDIFAKMHEEGGTMTKEDFATYYQLYEAMVMTPYFPQPDCLIFLESDYEDVINRIAERGRQMEIETDEA
YWRALYARYVEWIENFNACPVVRININEYDVYGDIDSLDPVIEKIAKVIHTHRAIHKR
>Mature_218_residues
MYTIPNDAIITIAGTVGVGKSSLTKALAEKLNFRTSFEKVDNNPYLEKFYNDFDRWSFHLQIYFLAERFKEQKRMFEYGG
GFIQDRSIYEDVDIFAKMHEEGGTMTKEDFATYYQLYEAMVMTPYFPQPDCLIFLESDYEDVINRIAERGRQMEIETDEA
YWRALYARYVEWIENFNACPVVRININEYDVYGDIDSLDPVIEKIAKVIHTHRAIHKR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 25825; Mature: 25825

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTIPNDAIITIAGTVGVGKSSLTKALAEKLNFRTSFEKVDNNPYLEKFYNDFDRWSFHL
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCEEEEE
QIYFLAERFKEQKRMFEYGGGFIQDRSIYEDVDIFAKMHEEGGTMTKEDFATYYQLYEAM
EHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VMTPYFPQPDCLIFLESDYEDVINRIAERGRQMEIETDEAYWRALYARYVEWIENFNACP
HHCCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
VVRININEYDVYGDIDSLDPVIEKIAKVIHTHRAIHKR
EEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYTIPNDAIITIAGTVGVGKSSLTKALAEKLNFRTSFEKVDNNPYLEKFYNDFDRWSFHL
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCEEEEE
QIYFLAERFKEQKRMFEYGGGFIQDRSIYEDVDIFAKMHEEGGTMTKEDFATYYQLYEAM
EHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VMTPYFPQPDCLIFLESDYEDVINRIAERGRQMEIETDEAYWRALYARYVEWIENFNACP
HHCCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
VVRININEYDVYGDIDSLDPVIEKIAKVIHTHRAIHKR
EEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]