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The map label for this gene is dgk [H]

Identifier: 222152094

GI number: 222152094

Start: 1983721

End: 1984320

Strand: Direct

Name: dgk [H]

Synonym: MCCL_1851

Alternate gene names: 222152094

Gene position: 1983721-1984320 (Clockwise)

Preceding gene: 222152091

Following gene: 222152095

Centisome position: 94.36

GC content: 33.83

Gene sequence:

>600_bases
ATGGCACCTTTATTTATAGCGATAGAAGGACCGATCGGTGTCGGCAAAAGTTCACTGACTAAGAAACTATCAGCCACATT
AAATTTAACCCCTATCTATGAAATCGTTGAAGAAAATCCATTCCTATCTGATTTTTATGAAGATATTGATAAGTGGAGCT
TTCAGACAGAAATGTTTTTCCTATGCAACAGATATAAGGTTTTAACAGAATTATCAAATGATATATCTGCAGTCAGCGAT
TATCATATTCTAAAAAATAAAGTGTTCGCAAACAACACTTTGAATGAAAAAGAGTACAGGATGTTTGAAGACATCTACGA
TATATTGACACGTGAAGTTCGTAACCCTGACATTACTGTGTTTTTAACCGCTGATCTAGAGGTACTGAAACAGCGTATTC
AATTACGTAATCGCGACTTTGAATCTCATATCGAAGACGATTATTTAATAAAGTTAACCGAAGATTATAGACGTGTATAT
GAATCAATGAAACATGATCATCAGACGTTACTTATCGATACAAGCGATATGGACTTTGTAAACAATGCCGCAGATTATGA
GCATATCGTACAACAAATAAAAGATATTATAGGAGCTTAA

Upstream 100 bases:

>100_bases
CCATCTGCATAAAGATTTCATGATTCATTTCTTCATCCGCCTTATTCGTTTTATGGTACAATACAAATACTATTTTATTT
TAACATTTGAGGAGAGAAAT

Downstream 100 bases:

>100_bases
TATGTATACAATCCCTAATGATGCAATCATCACTATCGCTGGTACTGTCGGAGTCGGAAAAAGTTCGTTAACAAAAGCAC
TGGCTGAGAAGCTGAACTTC

Product: deoxypurine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAPLFIAIEGPIGVGKSSLTKKLSATLNLTPIYEIVEENPFLSDFYEDIDKWSFQTEMFFLCNRYKVLTELSNDISAVSD
YHILKNKVFANNTLNEKEYRMFEDIYDILTREVRNPDITVFLTADLEVLKQRIQLRNRDFESHIEDDYLIKLTEDYRRVY
ESMKHDHQTLLIDTSDMDFVNNAADYEHIVQQIKDIIGA

Sequences:

>Translated_199_residues
MAPLFIAIEGPIGVGKSSLTKKLSATLNLTPIYEIVEENPFLSDFYEDIDKWSFQTEMFFLCNRYKVLTELSNDISAVSD
YHILKNKVFANNTLNEKEYRMFEDIYDILTREVRNPDITVFLTADLEVLKQRIQLRNRDFESHIEDDYLIKLTEDYRRVY
ESMKHDHQTLLIDTSDMDFVNNAADYEHIVQQIKDIIGA
>Mature_198_residues
APLFIAIEGPIGVGKSSLTKKLSATLNLTPIYEIVEENPFLSDFYEDIDKWSFQTEMFFLCNRYKVLTELSNDISAVSDY
HILKNKVFANNTLNEKEYRMFEDIYDILTREVRNPDITVFLTADLEVLKQRIQLRNRDFESHIEDDYLIKLTEDYRRVYE
SMKHDHQTLLIDTSDMDFVNNAADYEHIVQQIKDIIGA

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 23392; Mature: 23261

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLFIAIEGPIGVGKSSLTKKLSATLNLTPIYEIVEENPFLSDFYEDIDKWSFQTEMFF
CCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LCNRYKVLTELSNDISAVSDYHILKNKVFANNTLNEKEYRMFEDIYDILTREVRNPDITV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
FLTADLEVLKQRIQLRNRDFESHIEDDYLIKLTEDYRRVYESMKHDHQTLLIDTSDMDFV
EEECCHHHHHHHHHHHCCCHHHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCHH
NNAADYEHIVQQIKDIIGA
CCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
APLFIAIEGPIGVGKSSLTKKLSATLNLTPIYEIVEENPFLSDFYEDIDKWSFQTEMFF
CCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LCNRYKVLTELSNDISAVSDYHILKNKVFANNTLNEKEYRMFEDIYDILTREVRNPDITV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
FLTADLEVLKQRIQLRNRDFESHIEDDYLIKLTEDYRRVYESMKHDHQTLLIDTSDMDFV
EEECCHHHHHHHHHHHCCCHHHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCHH
NNAADYEHIVQQIKDIIGA
CCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]