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The map label for this gene is ywcF [H]

Identifier: 222151985

GI number: 222151985

Start: 1881759

End: 1882961

Strand: Direct

Name: ywcF [H]

Synonym: MCCL_1742

Alternate gene names: 222151985

Gene position: 1881759-1882961 (Clockwise)

Preceding gene: 222151965

Following gene: 222151986

Centisome position: 89.51

GC content: 36.82

Gene sequence:

>1203_bases
ATGCCAACAAATAAGACTCGCAATAAACCAAAACGTTCGTGGATTGAAAGGATTGATTGGTGGCTTATTATATTAATACT
GGGTTTCTTTACAGTTAGCCTGGTAATTATCTCTTCTGCTATGACAGGTCAGCAGTATGGGACAAACTTTGCAGTCAGAC
AGGTCTTTTATTATTCATTAGGATTTGCCCTCGCACTCTCAATCATGTTTATACATCCAAAAACAATAAAGAAGTGGACT
TTCTTTATTTATTTACTAGGAAATATCGCTTTATTAGGACTGCTGATTTTACCAGAATCTTCATTTACCCCTGTGATCAA
TGGTGCAAAAAGCTGGTATGTATTTTTTGATAAGCTCAGCTTACAGCCTTCTGAATTTATGAAAATCATCCTTATGCTGA
CATTAAGCAAAGTAGTATATGATCATAATCGATTTACATATTACAAATCATTTCAGACGGACCTCATATTACTTCTTAAA
ATAGGATTAACCGCAATGATTCCAATGATACTTATATTATTGCAGAATGATCTCGGAACAACGCTTGTATTGCTTGCTAT
CATACTCGGTATCATCATTGTTTCTGGTGTGACATGGAAAATACTCGCACCTTTTCTTATTACGGTTTCATTGCTTGGTG
TCTCTATCATTATGATGATTATCTATAAACCATCGCTTATCGAGAAAGTACTTGGTATACAGACGTATCAGCTCGGCCGA
ATCAACTCATGGTTAAATCCTGGCCAGTATAGTGATGGGGAAGGATTTCACTTAATGGAATCCTTGAAAGCGATAGGTTC
TGGTGGATTGTTTGGTAAAGGTTATAAAGGCGGAGAAGTGTATATCCCCGAAAACCATACGGACTTCATTTTCTCAATTA
TCGGAGAAGAGTTCGGGTTCATCGGTTCGATTATAGTTTTAATATTGTTTTTAGCATTGTTTACACATCTCGTACGCCTA
GCTCAAATTACAGTCTCACCATTTTCATCAATATTCCTTGTTGGATTTATCAGTATGATTGCCTTCCACGTATTCCAGAA
CGTGGGCATGACGATACAAGTTGTACCGATAACAGGAATCCCATTACCATTTATCAGCTATGGGGGAAGTTCTTTATGGG
CACTTATGTGTGGTATCGGCGTTACATTAGCTATTTATTACCACTCTAATCCCGAACAACTGAAGAAGTTAAAGTCAAAA
TAA

Upstream 100 bases:

>100_bases
GACACAAAATTACCTTAAACTCGGGTAACTTATCTATATATACTTTCAGATGATTTATGTATAATAAAATTTATAATTAT
TTATGGTAAGGAGTAATCGC

Downstream 100 bases:

>100_bases
AAACAAGCGTTCAATTCTGAACGCTTGTTTTTATTCTATTATGTACTATTTCAACTTTGCAGGCGCAACATTTGGTAATG
TACGCATTACCTCAAGACGT

Product: rod shape determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MPTNKTRNKPKRSWIERIDWWLIILILGFFTVSLVIISSAMTGQQYGTNFAVRQVFYYSLGFALALSIMFIHPKTIKKWT
FFIYLLGNIALLGLLILPESSFTPVINGAKSWYVFFDKLSLQPSEFMKIILMLTLSKVVYDHNRFTYYKSFQTDLILLLK
IGLTAMIPMILILLQNDLGTTLVLLAIILGIIIVSGVTWKILAPFLITVSLLGVSIIMMIIYKPSLIEKVLGIQTYQLGR
INSWLNPGQYSDGEGFHLMESLKAIGSGGLFGKGYKGGEVYIPENHTDFIFSIIGEEFGFIGSIIVLILFLALFTHLVRL
AQITVSPFSSIFLVGFISMIAFHVFQNVGMTIQVVPITGIPLPFISYGGSSLWALMCGIGVTLAIYYHSNPEQLKKLKSK

Sequences:

>Translated_400_residues
MPTNKTRNKPKRSWIERIDWWLIILILGFFTVSLVIISSAMTGQQYGTNFAVRQVFYYSLGFALALSIMFIHPKTIKKWT
FFIYLLGNIALLGLLILPESSFTPVINGAKSWYVFFDKLSLQPSEFMKIILMLTLSKVVYDHNRFTYYKSFQTDLILLLK
IGLTAMIPMILILLQNDLGTTLVLLAIILGIIIVSGVTWKILAPFLITVSLLGVSIIMMIIYKPSLIEKVLGIQTYQLGR
INSWLNPGQYSDGEGFHLMESLKAIGSGGLFGKGYKGGEVYIPENHTDFIFSIIGEEFGFIGSIIVLILFLALFTHLVRL
AQITVSPFSSIFLVGFISMIAFHVFQNVGMTIQVVPITGIPLPFISYGGSSLWALMCGIGVTLAIYYHSNPEQLKKLKSK
>Mature_399_residues
PTNKTRNKPKRSWIERIDWWLIILILGFFTVSLVIISSAMTGQQYGTNFAVRQVFYYSLGFALALSIMFIHPKTIKKWTF
FIYLLGNIALLGLLILPESSFTPVINGAKSWYVFFDKLSLQPSEFMKIILMLTLSKVVYDHNRFTYYKSFQTDLILLLKI
GLTAMIPMILILLQNDLGTTLVLLAIILGIIIVSGVTWKILAPFLITVSLLGVSIIMMIIYKPSLIEKVLGIQTYQLGRI
NSWLNPGQYSDGEGFHLMESLKAIGSGGLFGKGYKGGEVYIPENHTDFIFSIIGEEFGFIGSIIVLILFLALFTHLVRLA
QITVSPFSSIFLVGFISMIAFHVFQNVGMTIQVVPITGIPLPFISYGGSSLWALMCGIGVTLAIYYHSNPEQLKKLKSK

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=391, Percent_Identity=29.156010230179, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786277, Length=403, Percent_Identity=29.0322580645161, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44828; Mature: 44697

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNKTRNKPKRSWIERIDWWLIILILGFFTVSLVIISSAMTGQQYGTNFAVRQVFYYSL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHH
GFALALSIMFIHPKTIKKWTFFIYLLGNIALLGLLILPESSFTPVINGAKSWYVFFDKLS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECC
LQPSEFMKIILMLTLSKVVYDHNRFTYYKSFQTDLILLLKIGLTAMIPMILILLQNDLGT
CCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TLVLLAIILGIIIVSGVTWKILAPFLITVSLLGVSIIMMIIYKPSLIEKVLGIQTYQLGR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEECCC
INSWLNPGQYSDGEGFHLMESLKAIGSGGLFGKGYKGGEVYIPENHTDFIFSIIGEEFGF
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
IGSIIVLILFLALFTHLVRLAQITVSPFSSIFLVGFISMIAFHVFQNVGMTIQVVPITGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PLPFISYGGSSLWALMCGIGVTLAIYYHSNPEQLKKLKSK
CCHHHHCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
PTNKTRNKPKRSWIERIDWWLIILILGFFTVSLVIISSAMTGQQYGTNFAVRQVFYYSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHH
GFALALSIMFIHPKTIKKWTFFIYLLGNIALLGLLILPESSFTPVINGAKSWYVFFDKLS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECC
LQPSEFMKIILMLTLSKVVYDHNRFTYYKSFQTDLILLLKIGLTAMIPMILILLQNDLGT
CCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TLVLLAIILGIIIVSGVTWKILAPFLITVSLLGVSIIMMIIYKPSLIEKVLGIQTYQLGR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEECCC
INSWLNPGQYSDGEGFHLMESLKAIGSGGLFGKGYKGGEVYIPENHTDFIFSIIGEEFGF
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
IGSIIVLILFLALFTHLVRLAQITVSPFSSIFLVGFISMIAFHVFQNVGMTIQVVPITGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PLPFISYGGSSLWALMCGIGVTLAIYYHSNPEQLKKLKSK
CCHHHHCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]