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The map label for this gene is asd [H]

Identifier: 222151296

GI number: 222151296

Start: 1158012

End: 1159001

Strand: Direct

Name: asd [H]

Synonym: MCCL_1049

Alternate gene names: 222151296

Gene position: 1158012-1159001 (Clockwise)

Preceding gene: 222151295

Following gene: 222151297

Centisome position: 55.08

GC content: 39.39

Gene sequence:

>990_bases
ATGTATAAAATTGCAGTTGTAGGTGCTACAGGTTTAGTCGGACAAAAAATGCTTGAAGTTTTAGAAAGAAAACAGATTCC
GTTCAATGAACTCGTATTATATTCATCTCCACGTTCAGCCGGTAAATCTGTAGAATATCAAGGTAAAACGTATACAGTAA
GAGCTTTAAACGAAGAAGAAGCAGTCCAGAAATTTGATTTTGTCCTTATGAGTGCAGGAGGTGCTACAAGTGAACGCTTT
TCACCAATCTTTGAATCTGCCGGCAGCATCGTAATCGATAATTCAAGTGCTTTTAGAATGCATGAGGATATCGACCTCAT
TGTTCCTGAAGTCAATTCACCCAAACTCAAGCGTAAAATTATCGCTAATCCGAACTGTTCTACGATTCAGTCTGTCGTAC
CACTTAAACCACTGCAAGATAAATATGGTATTAGACGCGTTGCCTACACAACTTATCAAGCTGTGTCAGGAAGCGGTGCT
GCAGGTATCAACGACCTTAAAAATGGCGCACAAGGCATTGCACCGACAAACTATCCCCACCCTATCTATAACAATGCTTT
ACCTCATATCGATGTATTTTTAGACAATGGATATACAAAGGAAGAACAGAAGATGATTGATGAGACGAAGAAGATTCTTG
GATTACAAGATGTAAAGGTAACAGCAACTTGTGTCAGAATCCCAGTTCAGGATAGTCATTCTGTCGCAATCAATGTCACA
CTTGATAAAGAAGCTACAGTTGAAGAAATAAAACAGCTCTTCGAAAATGACGATTCAGTCGTGCTTATAGATAATCCACC
GGACAATGAATACCCAATGGCGATTACAGCGACAGGAACTGATCATGTTTATGTAGGACGAATCAGAAGAGATGACTCAT
TAGAAAATTCCTTCCATATCTGGTGCACTGCCGATAACCTTCTAAAAGGTGCAGCACTAAATGCGGTTCAAATTTTAGAA
CAGATCCATACGCACCAATTAAATCGATGA

Upstream 100 bases:

>100_bases
TGAAATATCGATTTCATATGTTATAGATAAAGAAAACGGTGAACATGCAGTACAGTCATTATGTAAAGTATTTAATATAT
AAAATTAAGGAGAGTCAATT

Downstream 100 bases:

>100_bases
TTCTAAGGAGCGATATAATGAACATACACTTTAAAGGAACAGGTGTTGCAGTAACCACACCATTCAACGGACAGACGATA
GATTACAACTTATTTGAAGA

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MYKIAVVGATGLVGQKMLEVLERKQIPFNELVLYSSPRSAGKSVEYQGKTYTVRALNEEEAVQKFDFVLMSAGGATSERF
SPIFESAGSIVIDNSSAFRMHEDIDLIVPEVNSPKLKRKIIANPNCSTIQSVVPLKPLQDKYGIRRVAYTTYQAVSGSGA
AGINDLKNGAQGIAPTNYPHPIYNNALPHIDVFLDNGYTKEEQKMIDETKKILGLQDVKVTATCVRIPVQDSHSVAINVT
LDKEATVEEIKQLFENDDSVVLIDNPPDNEYPMAITATGTDHVYVGRIRRDDSLENSFHIWCTADNLLKGAALNAVQILE
QIHTHQLNR

Sequences:

>Translated_329_residues
MYKIAVVGATGLVGQKMLEVLERKQIPFNELVLYSSPRSAGKSVEYQGKTYTVRALNEEEAVQKFDFVLMSAGGATSERF
SPIFESAGSIVIDNSSAFRMHEDIDLIVPEVNSPKLKRKIIANPNCSTIQSVVPLKPLQDKYGIRRVAYTTYQAVSGSGA
AGINDLKNGAQGIAPTNYPHPIYNNALPHIDVFLDNGYTKEEQKMIDETKKILGLQDVKVTATCVRIPVQDSHSVAINVT
LDKEATVEEIKQLFENDDSVVLIDNPPDNEYPMAITATGTDHVYVGRIRRDDSLENSFHIWCTADNLLKGAALNAVQILE
QIHTHQLNR
>Mature_329_residues
MYKIAVVGATGLVGQKMLEVLERKQIPFNELVLYSSPRSAGKSVEYQGKTYTVRALNEEEAVQKFDFVLMSAGGATSERF
SPIFESAGSIVIDNSSAFRMHEDIDLIVPEVNSPKLKRKIIANPNCSTIQSVVPLKPLQDKYGIRRVAYTTYQAVSGSGA
AGINDLKNGAQGIAPTNYPHPIYNNALPHIDVFLDNGYTKEEQKMIDETKKILGLQDVKVTATCVRIPVQDSHSVAINVT
LDKEATVEEIKQLFENDDSVVLIDNPPDNEYPMAITATGTDHVYVGRIRRDDSLENSFHIWCTADNLLKGAALNAVQILE
QIHTHQLNR

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=333, Percent_Identity=31.2312312312312, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=24.5231607629428, Blast_Score=95, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=385, Percent_Identity=29.3506493506493, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36374; Mature: 36374

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKIAVVGATGLVGQKMLEVLERKQIPFNELVLYSSPRSAGKSVEYQGKTYTVRALNEEE
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEECCCEEEEEECCHHH
AVQKFDFVLMSAGGATSERFSPIFESAGSIVIDNSSAFRMHEDIDLIVPEVNSPKLKRKI
HHHHHEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCEEEECCCEEEECCCCCCHHHHEE
IANPNCSTIQSVVPLKPLQDKYGIRRVAYTTYQAVSGSGAAGINDLKNGAQGIAPTNYPH
ECCCCHHHHHHHCCCCCCCHHHCCEEEEEEEHHHCCCCCCCCHHHHHCCCCCCCCCCCCC
PIYNNALPHIDVFLDNGYTKEEQKMIDETKKILGLQDVKVTATCVRIPVQDSHSVAINVT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEEEEE
LDKEATVEEIKQLFENDDSVVLIDNPPDNEYPMAITATGTDHVYVGRIRRDDSLENSFHI
ECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCEEE
WCTADNLLKGAALNAVQILEQIHTHQLNR
EEECCHHHCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYKIAVVGATGLVGQKMLEVLERKQIPFNELVLYSSPRSAGKSVEYQGKTYTVRALNEEE
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEECCCEEEEEECCHHH
AVQKFDFVLMSAGGATSERFSPIFESAGSIVIDNSSAFRMHEDIDLIVPEVNSPKLKRKI
HHHHHEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCEEEECCCEEEECCCCCCHHHHEE
IANPNCSTIQSVVPLKPLQDKYGIRRVAYTTYQAVSGSGAAGINDLKNGAQGIAPTNYPH
ECCCCHHHHHHHCCCCCCCHHHCCEEEEEEEHHHCCCCCCCCHHHHHCCCCCCCCCCCCC
PIYNNALPHIDVFLDNGYTKEEQKMIDETKKILGLQDVKVTATCVRIPVQDSHSVAINVT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEEEEE
LDKEATVEEIKQLFENDDSVVLIDNPPDNEYPMAITATGTDHVYVGRIRRDDSLENSFHI
ECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCEEE
WCTADNLLKGAALNAVQILEQIHTHQLNR
EEECCHHHCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]