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The map label for this gene is msrR [H]

Identifier: 222151267

GI number: 222151267

Start: 1128916

End: 1129857

Strand: Direct

Name: msrR [H]

Synonym: MCCL_1020

Alternate gene names: 222151267

Gene position: 1128916-1129857 (Clockwise)

Preceding gene: 222151265

Following gene: 222151269

Centisome position: 53.7

GC content: 36.41

Gene sequence:

>942_bases
ATGAGCGAAGGGATAACGCCAAGAAGAAAAGGAAAGAAAATCAGATTAAAAAAACTACCATTTGTAATTTTGGGATTAGT
TTTATTACTTATACTGGTAGTAGTTTTTATCAAATCAAGTTATAATAGTGGTCTTGATTTAGCAGCAAGACATGGGCAAA
AGCATGTCAACTATGACTTTAATGGAGTATCTAATAAAGACGGTAAATCAAATGTTTTAATTTTAGGTCAAGATCGCATG
ATTGATGGATCAGCAAGAACGGACTCTATTATGATCGCACAATACGACTTCCTTAATAAGAAGGTAAAAATCATTTCAGT
CATGCGCGATATATATGCTGAAATTCCAGGATATAGAAACTATAAAATTAATACAGCCTACACGTTAGGTGGGCCAGAGT
TACTGCGTAAGACGATAGAGAAAAATTTAGGTATTCCAATAGAACATTATGCAATTATAGATTTCAAAGGGTTCGAGGCC
ATGGTAGATGAAATCTCACCTTCTGGAGTACCGGTAAATGTGGAAAAGGATATGTCTGAAAATATCGGTGTATCTTTAAA
GAAAGGTCAGCATAATCTAAATGGTAAAGAATTATTAGGATATGCTCGTTTTAGACATGATGAAGAAGGGGACTTTGGAC
GCGTAAGACGTCAGCAGCAAGTAATTTCTGCGTTAAAACAAGAAATGGTCAGTCTTCCTGTGTTCTTTAAAACACCGAAA
TTAGCGGGAATTGCAAGAGGTTATGTCAATACCGACCTTAAAGATGGCGAGATATTTCGAATGGGAACAAGCTTTGTAAT
CCGTGGAGACAAGAAGCAGAGCACATTGACCGTACCAGTAAAAGGAAGTTTCCAGCAGGCAAGCTATCCTGAAGCAGGGG
CTGTGCTTGAAATAGATAAAGAAATGAATAAAAAGGCGATACAGAAGTTCTTAAATGAATAA

Upstream 100 bases:

>100_bases
TATTTTACTTTATTATTTGGAAAATAAACCGATATATGCTTGCAATAATGTAAATTCTTTTATAAGTTTATTATATTGTA
ATATAGAAAGCAGGGTATGT

Downstream 100 bases:

>100_bases
AAACAGGAGAAGCGATTGCTTCTCCTGTTTTTATTGTTGATCTGATAATAATTGACCCGCTACTGCATAACGTTCTTTTT
TAAGTTCTTCAATAAATACA

Product: peptide methionine sulfoxide reductase regulator MsrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSEGITPRRKGKKIRLKKLPFVILGLVLLLILVVVFIKSSYNSGLDLAARHGQKHVNYDFNGVSNKDGKSNVLILGQDRM
IDGSARTDSIMIAQYDFLNKKVKIISVMRDIYAEIPGYRNYKINTAYTLGGPELLRKTIEKNLGIPIEHYAIIDFKGFEA
MVDEISPSGVPVNVEKDMSENIGVSLKKGQHNLNGKELLGYARFRHDEEGDFGRVRRQQQVISALKQEMVSLPVFFKTPK
LAGIARGYVNTDLKDGEIFRMGTSFVIRGDKKQSTLTVPVKGSFQQASYPEAGAVLEIDKEMNKKAIQKFLNE

Sequences:

>Translated_313_residues
MSEGITPRRKGKKIRLKKLPFVILGLVLLLILVVVFIKSSYNSGLDLAARHGQKHVNYDFNGVSNKDGKSNVLILGQDRM
IDGSARTDSIMIAQYDFLNKKVKIISVMRDIYAEIPGYRNYKINTAYTLGGPELLRKTIEKNLGIPIEHYAIIDFKGFEA
MVDEISPSGVPVNVEKDMSENIGVSLKKGQHNLNGKELLGYARFRHDEEGDFGRVRRQQQVISALKQEMVSLPVFFKTPK
LAGIARGYVNTDLKDGEIFRMGTSFVIRGDKKQSTLTVPVKGSFQQASYPEAGAVLEIDKEMNKKAIQKFLNE
>Mature_312_residues
SEGITPRRKGKKIRLKKLPFVILGLVLLLILVVVFIKSSYNSGLDLAARHGQKHVNYDFNGVSNKDGKSNVLILGQDRMI
DGSARTDSIMIAQYDFLNKKVKIISVMRDIYAEIPGYRNYKINTAYTLGGPELLRKTIEKNLGIPIEHYAIIDFKGFEAM
VDEISPSGVPVNVEKDMSENIGVSLKKGQHNLNGKELLGYARFRHDEEGDFGRVRRQQQVISALKQEMVSLPVFFKTPKL
AGIARGYVNTDLKDGEIFRMGTSFVIRGDKKQSTLTVPVKGSFQQASYPEAGAVLEIDKEMNKKAIQKFLNE

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 35084; Mature: 34953

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGITPRRKGKKIRLKKLPFVILGLVLLLILVVVFIKSSYNSGLDLAARHGQKHVNYDF
CCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC
NGVSNKDGKSNVLILGQDRMIDGSARTDSIMIAQYDFLNKKVKIISVMRDIYAEIPGYRN
CCCCCCCCCCCEEEEECCCEECCCCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHCCCCCC
YKINTAYTLGGPELLRKTIEKNLGIPIEHYAIIDFKGFEAMVDEISPSGVPVNVEKDMSE
EEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHCCCCCCEEEECCCCCC
NIGVSLKKGQHNLNGKELLGYARFRHDEEGDFGRVRRQQQVISALKQEMVSLPVFFKTPK
CCCEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCC
LAGIARGYVNTDLKDGEIFRMGTSFVIRGDKKQSTLTVPVKGSFQQASYPEAGAVLEIDK
HHHHHHCCCCCCCCCCEEEEECCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEECH
EMNKKAIQKFLNE
HHHHHHHHHHHCC
>Mature Secondary Structure 
SEGITPRRKGKKIRLKKLPFVILGLVLLLILVVVFIKSSYNSGLDLAARHGQKHVNYDF
CCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC
NGVSNKDGKSNVLILGQDRMIDGSARTDSIMIAQYDFLNKKVKIISVMRDIYAEIPGYRN
CCCCCCCCCCCEEEEECCCEECCCCCCCEEEEEEEHHHCCHHHHHHHHHHHHHHCCCCCC
YKINTAYTLGGPELLRKTIEKNLGIPIEHYAIIDFKGFEAMVDEISPSGVPVNVEKDMSE
EEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHCCCCCCEEEECCCCCC
NIGVSLKKGQHNLNGKELLGYARFRHDEEGDFGRVRRQQQVISALKQEMVSLPVFFKTPK
CCCEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCC
LAGIARGYVNTDLKDGEIFRMGTSFVIRGDKKQSTLTVPVKGSFQQASYPEAGAVLEIDK
HHHHHHCCCCCCCCCCEEEEECCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEECH
EMNKKAIQKFLNE
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]