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The map label for this gene is pqqL [C]

Identifier: 222151114

GI number: 222151114

Start: 950987

End: 952177

Strand: Direct

Name: pqqL [C]

Synonym: MCCL_0865

Alternate gene names: 222151114

Gene position: 950987-952177 (Clockwise)

Preceding gene: 222151113

Following gene: 222151115

Centisome position: 45.24

GC content: 35.68

Gene sequence:

>1191_bases
TTGGAGCATATTAAACTTAAGAATGATATGACGTTTGCATATCACGAAACAAAGTTAGAGGTTGTGCATATTGGACTTTA
TATTAAAGTGGGTACATCGGATGAGGAAGGTTATCCATCAGGTATCGCGCATTTTATTGAACATATGGTATTTAAAGGGA
CGAAGCAGTTTCCATTTCAAGAGTTATCAGATAAAATTGATGCAATCGGTGGAGAAGTCAATGCCTATACAACGAAGACA
TATACATGTTATTCGATTAAGACGTTAAAACGTTTTGAACGTGTTGCGATTGAATTGCTGAAAGAAATGGTCTTCTGTGC
TACGTTCCCGAATGATGAACTAGAAAAAGAACGTCAGGTCATTCTTGAAGAGATAAAAATGATCGAAGATGATGATGAAG
AACGTGCATTCGAACAATTTGAAGCTGTATTATTCCAAGGGTCACCATATAATACACCGATTCTTGGTACGGCTGACAGT
GTGAATAATATTACTCAGACAATGCTTGAAGATTTTTATCATAAGTTTTATCAGCCGAATAATATGATCTTGTCGTATGT
TGGAACTGACTATCATTTTATTAAGGATTACTTTGAGCAATTTAACGCTGTTCATAATGTTAGACGCCCGCTGAAAAGAT
TTACAATGAACACGATGCATCTTACGCATCATAAAGAAAGTATGGAACAAGCACATGTTATACTGGCGCATAGAGGAGTA
AGCTATCTGGATGAAAAAAGTACATGCTATGAAATTATAAACAATATCTATGGTGGCAGTATGACGAGTCTGCTATTCAG
AAGGTTAAGGGAAGCACAAGGATTATGCTATGCATTATATTCATCGGTCGATGCTTATGAAGAGGGTGGTATTCTTTATA
CATACTTCGCTACTGACGTCAAAAACATAGAGCGATGTATGACAGAGATTCATCTTATACACAAACAGCTTGCAGCAGGT
ATTGACGAATCGTTGCTTTTAAAAACCAAACATTACCTTGTAACAAATTTATATATGAATCTAGATTATGATGGCTCCAT
TATGGAGCATATGGGTAAGAGCATACTGCTTTATAATAAGATATATGAGATACATGAACTTGAAGATAAAATAATGGCTG
TTACATTAGAAGAGGTTGATGAAGCGCTGCAAGTTTTCAAGAAAGCGTATGCAAGTTACCGAATTTACTAG

Upstream 100 bases:

>100_bases
GCTGTTAGAAGAAGAGAAGAAAGCATCAGAAGAAAAATAGAGCATTAAGGTGAGGCGATATGTCTCACCTTTTTATTTGA
TTTGTCTGTGAGGAGATTAT

Downstream 100 bases:

>100_bases
GTTTCTATAGATTAATCCTTGCTAAAAATGTATAATATGGATGACTATATAACAAGGAGATGTAACTATGGTATTTGATA
AGATTCAGGTGAATGGTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MEHIKLKNDMTFAYHETKLEVVHIGLYIKVGTSDEEGYPSGIAHFIEHMVFKGTKQFPFQELSDKIDAIGGEVNAYTTKT
YTCYSIKTLKRFERVAIELLKEMVFCATFPNDELEKERQVILEEIKMIEDDDEERAFEQFEAVLFQGSPYNTPILGTADS
VNNITQTMLEDFYHKFYQPNNMILSYVGTDYHFIKDYFEQFNAVHNVRRPLKRFTMNTMHLTHHKESMEQAHVILAHRGV
SYLDEKSTCYEIINNIYGGSMTSLLFRRLREAQGLCYALYSSVDAYEEGGILYTYFATDVKNIERCMTEIHLIHKQLAAG
IDESLLLKTKHYLVTNLYMNLDYDGSIMEHMGKSILLYNKIYEIHELEDKIMAVTLEEVDEALQVFKKAYASYRIY

Sequences:

>Translated_396_residues
MEHIKLKNDMTFAYHETKLEVVHIGLYIKVGTSDEEGYPSGIAHFIEHMVFKGTKQFPFQELSDKIDAIGGEVNAYTTKT
YTCYSIKTLKRFERVAIELLKEMVFCATFPNDELEKERQVILEEIKMIEDDDEERAFEQFEAVLFQGSPYNTPILGTADS
VNNITQTMLEDFYHKFYQPNNMILSYVGTDYHFIKDYFEQFNAVHNVRRPLKRFTMNTMHLTHHKESMEQAHVILAHRGV
SYLDEKSTCYEIINNIYGGSMTSLLFRRLREAQGLCYALYSSVDAYEEGGILYTYFATDVKNIERCMTEIHLIHKQLAAG
IDESLLLKTKHYLVTNLYMNLDYDGSIMEHMGKSILLYNKIYEIHELEDKIMAVTLEEVDEALQVFKKAYASYRIY
>Mature_396_residues
MEHIKLKNDMTFAYHETKLEVVHIGLYIKVGTSDEEGYPSGIAHFIEHMVFKGTKQFPFQELSDKIDAIGGEVNAYTTKT
YTCYSIKTLKRFERVAIELLKEMVFCATFPNDELEKERQVILEEIKMIEDDDEERAFEQFEAVLFQGSPYNTPILGTADS
VNNITQTMLEDFYHKFYQPNNMILSYVGTDYHFIKDYFEQFNAVHNVRRPLKRFTMNTMHLTHHKESMEQAHVILAHRGV
SYLDEKSTCYEIINNIYGGSMTSLLFRRLREAQGLCYALYSSVDAYEEGGILYTYFATDVKNIERCMTEIHLIHKQLAAG
IDESLLLKTKHYLVTNLYMNLDYDGSIMEHMGKSILLYNKIYEIHELEDKIMAVTLEEVDEALQVFKKAYASYRIY

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=395, Percent_Identity=27.0886075949367, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI46593007, Length=393, Percent_Identity=26.2086513994911, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24308013, Length=418, Percent_Identity=22.7272727272727, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1787770, Length=174, Percent_Identity=32.183908045977, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71999683, Length=406, Percent_Identity=23.8916256157635, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17553678, Length=395, Percent_Identity=22.5316455696203, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6323192, Length=399, Percent_Identity=24.3107769423559, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21357875, Length=389, Percent_Identity=26.7352185089974, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24646943, Length=389, Percent_Identity=26.7352185089974, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19921772, Length=423, Percent_Identity=19.6217494089835, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46236; Mature: 46236

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHIKLKNDMTFAYHETKLEVVHIGLYIKVGTSDEEGYPSGIAHFIEHMVFKGTKQFPFQ
CCCEECCCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHH
ELSDKIDAIGGEVNAYTTKTYTCYSIKTLKRFERVAIELLKEMVFCATFPNDELEKERQV
HHHHHHHHCCCCCEEEEECEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILEEIKMIEDDDEERAFEQFEAVLFQGSPYNTPILGTADSVNNITQTMLEDFYHKFYQPN
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCC
NMILSYVGTDYHFIKDYFEQFNAVHNVRRPLKRFTMNTMHLTHHKESMEQAHVILAHRGV
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SYLDEKSTCYEIINNIYGGSMTSLLFRRLREAQGLCYALYSSVDAYEEGGILYTYFATDV
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHH
KNIERCMTEIHLIHKQLAAGIDESLLLKTKHYLVTNLYMNLDYDGSIMEHMGKSILLYNK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHCCCCEEHHHH
IYEIHELEDKIMAVTLEEVDEALQVFKKAYASYRIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEHIKLKNDMTFAYHETKLEVVHIGLYIKVGTSDEEGYPSGIAHFIEHMVFKGTKQFPFQ
CCCEECCCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHH
ELSDKIDAIGGEVNAYTTKTYTCYSIKTLKRFERVAIELLKEMVFCATFPNDELEKERQV
HHHHHHHHCCCCCEEEEECEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILEEIKMIEDDDEERAFEQFEAVLFQGSPYNTPILGTADSVNNITQTMLEDFYHKFYQPN
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCC
NMILSYVGTDYHFIKDYFEQFNAVHNVRRPLKRFTMNTMHLTHHKESMEQAHVILAHRGV
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SYLDEKSTCYEIINNIYGGSMTSLLFRRLREAQGLCYALYSSVDAYEEGGILYTYFATDV
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHH
KNIERCMTEIHLIHKQLAAGIDESLLLKTKHYLVTNLYMNLDYDGSIMEHMGKSILLYNK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHCCCCEEHHHH
IYEIHELEDKIMAVTLEEVDEALQVFKKAYASYRIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]