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The map label for this gene is des [H]

Identifier: 222150404

GI number: 222150404

Start: 156900

End: 157892

Strand: Direct

Name: des [H]

Synonym: MCCL_0154

Alternate gene names: 222150404

Gene position: 156900-157892 (Clockwise)

Preceding gene: 222150403

Following gene: 222150409

Centisome position: 7.46

GC content: 35.15

Gene sequence:

>993_bases
ATGTTAAGAAAGATGGTTAAGCCTTATGAGAAATCAGCACTACAAATAAGTTTAGTCCAGGTGCTAAATACACTGGTTCC
TTATTTAGTGCTTGTAGCGATAAGTATGTTAAGTTACAGTGTTTCTCCATGGATATCAGTAGCTGTTAGTATTGTGGCAG
CATTCTTCCTAGTTCGAACGTTTATTATATTTCATGACTGTTGTCATGGTTCGTTCTTTAAGAATAAGAAGTGGAACGAT
GCAATGGGAAATTTTACTGGATTTTTGACGATGTTTCCGTATCAGCAATGGCGCAGAGAGCATAATATTCATCATGCAAC
AAGTGGTAACCTTGATAAGAAAGGCATCGGGGATATATGGATGATGACCATTGATGAATACGAAGCAGCAAGTAAATGGA
AGCAACGTGGTTATCGTATGTATCGTAATCCAGTTGTTATGTTTGTTTTAGGGCCGATATATTTATTGTTCGTTACAAAC
AGAATTAATAGTAAAGGTGCCAAGCAGAAAGAAAAATTAAATACGTATTTTCATAATATTGCAATCTTGGTCGTGTATGG
ATCTATTATCTGGTACTTTGGATTTGCATTCTTTGCAGCGGTATTTCTGCCGATTATGTTTATCGGGGCAATGCTTGGTA
TATGGATGTTCTATATTCAGCATACATTTGAAGAATCGTATTTTGAAGAGAACTCTGAGTGGGATTATGTTAAAGCTGCA
GTTGAAGGTAGTTCATATTACAAATTACCAAAATTATTGCAGTGGTTGACAGGGAACATTGGGTTCCATCATGTGCATCA
TTTAAGTCCGAGAATTCCAAATTACTATCTTGAAACTGCACACGAAGAAGTTAAACCACTGCAGTATGCGACGACAATCA
CATTTAAACAAAGTCTGGAGACGATTAAATATAAACTTTACGATGAGAAGAGAAAAGTGTTTATCACATTTAAAGATTAT
TATCGTAATTATGCAAAGAAAAGAACAATTTAA

Upstream 100 bases:

>100_bases
ATTAGTACTAGGTAATAATATTAACTAACAATCCTCTTCGGTATCGTGGTTTCATTATTATTTTATTTAGAGGTGACTTA
TGGAAAGAGACAAGAAGTTA

Downstream 100 bases:

>100_bases
AAACGAGAATGGAATTTAATTCCATTCTCGTTTTTATTTAAAGAATACTTCGATAATGTAATCCAGATTATCGTCTGTAA
GTTGTAGTGTCGATTCATTC

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLRKMVKPYEKSALQISLVQVLNTLVPYLVLVAISMLSYSVSPWISVAVSIVAAFFLVRTFIIFHDCCHGSFFKNKKWND
AMGNFTGFLTMFPYQQWRREHNIHHATSGNLDKKGIGDIWMMTIDEYEAASKWKQRGYRMYRNPVVMFVLGPIYLLFVTN
RINSKGAKQKEKLNTYFHNIAILVVYGSIIWYFGFAFFAAVFLPIMFIGAMLGIWMFYIQHTFEESYFEENSEWDYVKAA
VEGSSYYKLPKLLQWLTGNIGFHHVHHLSPRIPNYYLETAHEEVKPLQYATTITFKQSLETIKYKLYDEKRKVFITFKDY
YRNYAKKRTI

Sequences:

>Translated_330_residues
MLRKMVKPYEKSALQISLVQVLNTLVPYLVLVAISMLSYSVSPWISVAVSIVAAFFLVRTFIIFHDCCHGSFFKNKKWND
AMGNFTGFLTMFPYQQWRREHNIHHATSGNLDKKGIGDIWMMTIDEYEAASKWKQRGYRMYRNPVVMFVLGPIYLLFVTN
RINSKGAKQKEKLNTYFHNIAILVVYGSIIWYFGFAFFAAVFLPIMFIGAMLGIWMFYIQHTFEESYFEENSEWDYVKAA
VEGSSYYKLPKLLQWLTGNIGFHHVHHLSPRIPNYYLETAHEEVKPLQYATTITFKQSLETIKYKLYDEKRKVFITFKDY
YRNYAKKRTI
>Mature_330_residues
MLRKMVKPYEKSALQISLVQVLNTLVPYLVLVAISMLSYSVSPWISVAVSIVAAFFLVRTFIIFHDCCHGSFFKNKKWND
AMGNFTGFLTMFPYQQWRREHNIHHATSGNLDKKGIGDIWMMTIDEYEAASKWKQRGYRMYRNPVVMFVLGPIYLLFVTN
RINSKGAKQKEKLNTYFHNIAILVVYGSIIWYFGFAFFAAVFLPIMFIGAMLGIWMFYIQHTFEESYFEENSEWDYVKAA
VEGSSYYKLPKLLQWLTGNIGFHHVHHLSPRIPNYYLETAHEEVKPLQYATTITFKQSLETIKYKLYDEKRKVFITFKDY
YRNYAKKRTI

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71999459, Length=255, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 38956; Mature: 38956

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCEEEEEEHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHCCCCCEEEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]