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The map label for this gene is moaB [H]

Identifier: 222150396

GI number: 222150396

Start: 151610

End: 152110

Strand: Direct

Name: moaB [H]

Synonym: MCCL_0146

Alternate gene names: 222150396

Gene position: 151610-152110 (Clockwise)

Preceding gene: 222150395

Following gene: 222150398

Centisome position: 7.21

GC content: 38.12

Gene sequence:

>501_bases
TTGGAACATTCAAATGACGTGCGTAAACAATTACTGGTTGGTGTGATTACAGTTAGTGATACGAGAGATTATGATACAGA
CAAAGGTGGAAAAGCGATTATCGAGCATTTGAAGACCATCGATATCGATGTTTCACGTGACAATTATTTAATTGCAAAAG
ATGATCAGGCTGACATTCGTGCAAGTATTATGAAATTATTGCATGAAAAAGTTGATGTTATTATTACAACAGGTGGTACA
GGTGTTGCGAAGCGTGATGTTACAATTGAAGTTGTCCAATCGATTATCGATAAAGAAATAGAAGGCTTCGGGGAAATTTT
TAGATACTTAAGCTATTCAGAAGATGTCGGGACACGTGCGATGCTATCTCGCGCATTATGTGGCACGAAAGACAATACCG
TAATCTTCTCGATTCCGGGCTCAGTTGGTGCAGTAAATCTTGCGATGAAAAAGCTCATTACACAAGAGATTCATCACATT
GTGCATGAGCTTAATAAGTAA

Upstream 100 bases:

>100_bases
TTGTCTGGTTTAGAGGTGGTCGTATGCTTATTCATGAAGTTCAATCGATGGCGGAAGGCAAGACAGTTTATCATCAACTA
TTTGGTTAGGAGAGATAGTA

Downstream 100 bases:

>100_bases
TTAACGATTAAAATCACCATTTTTGCCGCCTGATTTATGTTCAAGATAAGTTGGTCCGATGATCATACCTTTATCAACGG
CCTTCGTCATATCATATATC

Product: molybdenum cofactor biosynthesis protein MoaB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MEHSNDVRKQLLVGVITVSDTRDYDTDKGGKAIIEHLKTIDIDVSRDNYLIAKDDQADIRASIMKLLHEKVDVIITTGGT
GVAKRDVTIEVVQSIIDKEIEGFGEIFRYLSYSEDVGTRAMLSRALCGTKDNTVIFSIPGSVGAVNLAMKKLITQEIHHI
VHELNK

Sequences:

>Translated_166_residues
MEHSNDVRKQLLVGVITVSDTRDYDTDKGGKAIIEHLKTIDIDVSRDNYLIAKDDQADIRASIMKLLHEKVDVIITTGGT
GVAKRDVTIEVVQSIIDKEIEGFGEIFRYLSYSEDVGTRAMLSRALCGTKDNTVIFSIPGSVGAVNLAMKKLITQEIHHI
VHELNK
>Mature_166_residues
MEHSNDVRKQLLVGVITVSDTRDYDTDKGGKAIIEHLKTIDIDVSRDNYLIAKDDQADIRASIMKLLHEKVDVIITTGGT
GVAKRDVTIEVVQSIIDKEIEGFGEIFRYLSYSEDVGTRAMLSRALCGTKDNTVIFSIPGSVGAVNLAMKKLITQEIHHI
VHELNK

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=138, Percent_Identity=35.5072463768116, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI10880983, Length=138, Percent_Identity=35.5072463768116, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787000, Length=146, Percent_Identity=32.8767123287671, Blast_Score=88, Evalue=2e-19,
Organism=Escherichia coli, GI1786190, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=138, Percent_Identity=37.6811594202899, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17136978, Length=158, Percent_Identity=32.9113924050633, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24638841, Length=158, Percent_Identity=32.9113924050633, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18407; Mature: 18407

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHSNDVRKQLLVGVITVSDTRDYDTDKGGKAIIEHLKTIDIDVSRDNYLIAKDDQADIR
CCCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCEEECCCCEEEECCCHHHHH
ASIMKLLHEKVDVIITTGGTGVAKRDVTIEVVQSIIDKEIEGFGEIFRYLSYSEDVGTRA
HHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MLSRALCGTKDNTVIFSIPGSVGAVNLAMKKLITQEIHHIVHELNK
HHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEHSNDVRKQLLVGVITVSDTRDYDTDKGGKAIIEHLKTIDIDVSRDNYLIAKDDQADIR
CCCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCEEECCCCEEEECCCHHHHH
ASIMKLLHEKVDVIITTGGTGVAKRDVTIEVVQSIIDKEIEGFGEIFRYLSYSEDVGTRA
HHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MLSRALCGTKDNTVIFSIPGSVGAVNLAMKKLITQEIHHIVHELNK
HHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA