Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 222111237

GI number: 222111237

Start: 2189802

End: 2190251

Strand: Direct

Name: nrdR

Synonym: Dtpsy_2045

Alternate gene names: 222111237

Gene position: 2189802-2190251 (Clockwise)

Preceding gene: 222111236

Following gene: 222111240

Centisome position: 57.68

GC content: 62.22

Gene sequence:

>450_bases
ATGAAGTGCCCCTTTTGCAGCCATCAGGAGACGCAGGTCGTCGAAACCCGCGTCTCCGAGGACGGGGACTTCATCCGCCG
CAGGCGCCAGTGCGGCGCCTGCGACAAGCGCTTCACGACCTACGAACGACCGGAAGTCAACTTCCCCACGGTCGTCAAGA
AGGACGGCCGCCGCGTCGAATACGACCGCGAGAAACTGCTGGGATCGTTCAAGCTGGCGCTGCGCAAGCGACCGGTGAGC
ACAGTGCAGATCGACTCGGCCATCGAGCGCATCGAGGAAAAGCTGCTCAACCTGGGGCAGCGCGAGATCCTGTCCAGCCG
CATCGGCGAGTTGGTCATGCGCGAGTTGAAGAAGCTCGACAAAGTAGCGTATGTGCGCTACGCCAGCGTGTACCGCAGCT
TCGAGGACATCGACGAGTTCCGCGCGCTGGTGGACGAAGTCCGCAAGTAA

Upstream 100 bases:

>100_bases
GCTGGACAACCCGCATGACGAGGCGAACCTGGAAGCCGTGCGCGCCAAGGTGCACGCGCTGACCAGCCGCTTCCCGGTCT
ATCGCTGATCGACCGCTGCG

Downstream 100 bases:

>100_bases
GCCGCCACGCTTCAGTCGCTCTTCTATTGATAGCTGGCAGCGCCCACTGGGCGGGCGCTGCAGCCGTTTTTGACCATCAC
CCCAGGCGGACTGCCGGAAT

Product: nrdr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKCPFCSHQETQVVETRVSEDGDFIRRRRQCGACDKRFTTYERPEVNFPTVVKKDGRRVEYDREKLLGSFKLALRKRPVS
TVQIDSAIERIEEKLLNLGQREILSSRIGELVMRELKKLDKVAYVRYASVYRSFEDIDEFRALVDEVRK

Sequences:

>Translated_149_residues
MKCPFCSHQETQVVETRVSEDGDFIRRRRQCGACDKRFTTYERPEVNFPTVVKKDGRRVEYDREKLLGSFKLALRKRPVS
TVQIDSAIERIEEKLLNLGQREILSSRIGELVMRELKKLDKVAYVRYASVYRSFEDIDEFRALVDEVRK
>Mature_149_residues
MKCPFCSHQETQVVETRVSEDGDFIRRRRQCGACDKRFTTYERPEVNFPTVVKKDGRRVEYDREKLLGSFKLALRKRPVS
TVQIDSAIERIEEKLLNLGQREILSSRIGELVMRELKKLDKVAYVRYASVYRSFEDIDEFRALVDEVRK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=51.4285714285714, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ACIET (B9MAC9)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002553501.1
- GeneID:   7385038
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_2045
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17608; Mature: 17608

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCSHQETQVVETRVSEDGDFIRRRRQCGACDKRFTTYERPEVNFPTVVKKDGRRVE
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHCCCCCCCCH
YDREKLLGSFKLALRKRPVSTVQIDSAIERIEEKLLNLGQREILSSRIGELVMRELKKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVAYVRYASVYRSFEDIDEFRALVDEVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCSHQETQVVETRVSEDGDFIRRRRQCGACDKRFTTYERPEVNFPTVVKKDGRRVE
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHCCCCCCCCH
YDREKLLGSFKLALRKRPVSTVQIDSAIERIEEKLLNLGQREILSSRIGELVMRELKKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KVAYVRYASVYRSFEDIDEFRALVDEVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA