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The map label for this gene is hsdR [H]

Identifier: 222110400

GI number: 222110400

Start: 1252504

End: 1254987

Strand: Direct

Name: hsdR [H]

Synonym: Dtpsy_1193

Alternate gene names: 222110400

Gene position: 1252504-1254987 (Clockwise)

Preceding gene: 222110395

Following gene: 222110401

Centisome position: 32.99

GC content: 63.33

Gene sequence:

>2484_bases
ATGGATAAAACCAAACTCTCCGAAAGCGACATTTGCGAAAAGTTCATCCGGCCGGCCATGGAGCAGGCGGGCTGGGACGG
CATGGACCAGATCTACCGGGAGTACCCGTTGCGCGCGGGCCGTGTGGTGGTGCGCGGCAGGCAGGCCCAGCGCGACAAAA
GCACCGTGCTGCGTGCCGACTACGCCCTGTTCTTCAAGGCCAACATCCCCCTGGCCGTGGTGGAGGCCAAGGACAACCAG
CATGCCGTGGGCGCAGGCATGGGGCAGGCCATCCAATATGCCGAGCTGCTGGGCGTGCCGTTCAGTTTCGCCAGCAATGG
CGATGGCTTCGTGTTCCGTGATGCCACGCTGGCCGATGGTGTGCTGGAGCGCAACCTGACTCTGGAGGAATTTCCGTCAC
CTGCCGAGCTGTGGAGTCGCTACTGCGCCTGGAAGGGCTGGTCCGCCGAAGAAAGCCGCATCGCCGGCTTTGACTACGCC
CCCAACAAGACCCCGCGCTACTACCAGCTGAACGCCGTGAACCGCGCTGTCGAAGCCATCGCCGCAGGGCAAGACCGCGT
GCTGCTGGTCATGGCCACCGGCACCGGCAAGACCTATACCGCCTTCCAGATCATCTGGCGCCTGTGGAAGAGCGGCGCCA
AGAAGCGCATCTTGTTCCTGGCCGACCGCAACATCCTCATCGACCAGACCATGGTCAACGACTTTCGCCCCTTCAAGGGC
GCCATGGCCAAGCTCAGCCCCAACGCCAAGGGCGTGGAGCGTGTCGATGCGCAGGGCGCGGTGTCGGTCGAAGACGTGGA
CTTGGCTGTCAACAAAACTACCAAGCTGGTGGACAAGAGCTACGAGATTTACTTGTCGCTGTACCAGGCCGTCACCGGCA
CCGAGGAAGAGCGCAACATCTACAAGCAGTTCAGCCCCGACTTTTTCGACCTGATCGTGGTGGACGAATGCCACCGGGGC
AGTGCAGCCGAAGACTCCGCTTGGCGCGACATCCTCACCTACTTTGCCGGCGCCACGCAGATCGGCCTCACCGCCACGCC
CAAAGAAACCAAGGACGTTTCCAACACCGACTACTTCGGCGAGCCCGTCTACACCTACAGCCTCAAGCAAGGCATCGAAG
ACGGCTACCTGGCGCCGTACAAGGTCATCCGCGTCGATCTGGACAAAGACACCTTTGGCTGGCGCCCCACGGCGGGCATG
ACCGACAAACACGGCCACGCCATCGAAGACCGCATCTACACCGGCGCCGACATGAACCGCAAGCTCGTGCTGGAGCAGCG
CGACGCCGTGGTGGCCGCCAAGATCACCGAATACCTCAAGGCCACCGACCGCTACGCCAAAACCATCGTCTTTTGCGAAG
ACATCGACCACGCCGCGCGCATGCGCCAAGCGCTGAGCAACGCCAACGCCGACCTGTGCGCCACCCAGCCCAAATATGTG
GTGCAGATCACCGGCGACAACATCGAAGGCAAGCTGGAACTCGACAACTTCATCGACCCCGAGAAAACCTACCCGGTGAT
CGCCACCACCTCCAAGCTCATGAGCACCGGGGTGGATGCCCAGACCTGCAAGCTCATCGTGCTGGACCAGACCATCAAGT
CCATGACGCTGTTCAAGCAGATCATCGGCCGTGGCACCCGCCTGCGCGAAGACCTGGGCAAGACCTGGTTCACCATCCTC
GACTTCAAGCGCGCCACTGAACTGTTTGCCGACAAGGACTTTGATGGCGAGCCCGTGCAAATCTACGAGCCGGGCAGCGG
GCAGCCCGTGGCGCCGCCCGAACCGGCAATGCCAGGCGACATTCCGGGCGACGCAGGCACGCCCGGCGGTGCGGCAAACC
CTCTGGACCCTCTTGACCCCCTGAACCCTCTTGGCCCCTTCGCGGGCGGCGGTGGTGCGGGTGCCGGCCCCAAGAAATAT
GTCCTCGGCAACAACGTCACCGTGTCCGTGGCGCGCGAGCGCGTGCAGTACCTCAACGCCCAGGGCAAGCTCATCACCGA
AAGCCTGCGCGACTACACCCGCATCAACCTGCGCAAGCAATACGACTCGCTCGACCAGTTCCTGCAGGCCTGGCAGCAGG
CCGACCGCAAGGCCGTGCTCCTGCAAGAGCTCGAAGGGCAGGGCGTGCCGCTGGAGGCCTTGGCCGACGAGGTAGGTAAA
GACCTCGACCCATTTGATCTGCTGCTGCATGTGGCCTATGACCAGCCCCCGCTCACCCGCCGCGAACGCGCCCGCCGCGT
GCAAAAGCGCAACGTCTTCACCCAATACGGCCCCGTGGCCCGCAAGGTGCTCGACGCCCTGCTCGACAAATACGCCGATG
AAGGCATCGCCACCATCGAGAGCAACGAAGTCTTCAAGCTCCAGCCCTTTACCGATCTGGGCAGCCCTGTCGAGCTGGTG
CGCAGCTTTGGTGGCCGCCCCCAATACCTCAGCGCACTGCAGGCGCTGGAGCAAGCGCTGTACGCTACGCACCCGGCCCA
CTAG

Upstream 100 bases:

>100_bases
AATGGTAGTGATTCTTTCGGTGGTCTCGGGCAGGGGCGGTAGTATCCGGTAACAACCACACGCCGCCTTTGCATGCACTG
GGGATGGTGCGAACTGCCGA

Downstream 100 bases:

>100_bases
CGGTGTGCCGCTGAGTACCGCCAAATACTCCTGATTTGATAGCTGCTGGCGCTTGATAGATAAGCGCTAGACCCTGTTTT
TGCGTAAATCCCGCGTTCCA

Product: ecoei r domain-containing protein

Products: NA

Alternate protein names: R.EcoAI [H]

Number of amino acids: Translated: 827; Mature: 827

Protein sequence:

>827_residues
MDKTKLSESDICEKFIRPAMEQAGWDGMDQIYREYPLRAGRVVVRGRQAQRDKSTVLRADYALFFKANIPLAVVEAKDNQ
HAVGAGMGQAIQYAELLGVPFSFASNGDGFVFRDATLADGVLERNLTLEEFPSPAELWSRYCAWKGWSAEESRIAGFDYA
PNKTPRYYQLNAVNRAVEAIAAGQDRVLLVMATGTGKTYTAFQIIWRLWKSGAKKRILFLADRNILIDQTMVNDFRPFKG
AMAKLSPNAKGVERVDAQGAVSVEDVDLAVNKTTKLVDKSYEIYLSLYQAVTGTEEERNIYKQFSPDFFDLIVVDECHRG
SAAEDSAWRDILTYFAGATQIGLTATPKETKDVSNTDYFGEPVYTYSLKQGIEDGYLAPYKVIRVDLDKDTFGWRPTAGM
TDKHGHAIEDRIYTGADMNRKLVLEQRDAVVAAKITEYLKATDRYAKTIVFCEDIDHAARMRQALSNANADLCATQPKYV
VQITGDNIEGKLELDNFIDPEKTYPVIATTSKLMSTGVDAQTCKLIVLDQTIKSMTLFKQIIGRGTRLREDLGKTWFTIL
DFKRATELFADKDFDGEPVQIYEPGSGQPVAPPEPAMPGDIPGDAGTPGGAANPLDPLDPLNPLGPFAGGGGAGAGPKKY
VLGNNVTVSVARERVQYLNAQGKLITESLRDYTRINLRKQYDSLDQFLQAWQQADRKAVLLQELEGQGVPLEALADEVGK
DLDPFDLLLHVAYDQPPLTRRERARRVQKRNVFTQYGPVARKVLDALLDKYADEGIATIESNEVFKLQPFTDLGSPVELV
RSFGGRPQYLSALQALEQALYATHPAH

Sequences:

>Translated_827_residues
MDKTKLSESDICEKFIRPAMEQAGWDGMDQIYREYPLRAGRVVVRGRQAQRDKSTVLRADYALFFKANIPLAVVEAKDNQ
HAVGAGMGQAIQYAELLGVPFSFASNGDGFVFRDATLADGVLERNLTLEEFPSPAELWSRYCAWKGWSAEESRIAGFDYA
PNKTPRYYQLNAVNRAVEAIAAGQDRVLLVMATGTGKTYTAFQIIWRLWKSGAKKRILFLADRNILIDQTMVNDFRPFKG
AMAKLSPNAKGVERVDAQGAVSVEDVDLAVNKTTKLVDKSYEIYLSLYQAVTGTEEERNIYKQFSPDFFDLIVVDECHRG
SAAEDSAWRDILTYFAGATQIGLTATPKETKDVSNTDYFGEPVYTYSLKQGIEDGYLAPYKVIRVDLDKDTFGWRPTAGM
TDKHGHAIEDRIYTGADMNRKLVLEQRDAVVAAKITEYLKATDRYAKTIVFCEDIDHAARMRQALSNANADLCATQPKYV
VQITGDNIEGKLELDNFIDPEKTYPVIATTSKLMSTGVDAQTCKLIVLDQTIKSMTLFKQIIGRGTRLREDLGKTWFTIL
DFKRATELFADKDFDGEPVQIYEPGSGQPVAPPEPAMPGDIPGDAGTPGGAANPLDPLDPLNPLGPFAGGGGAGAGPKKY
VLGNNVTVSVARERVQYLNAQGKLITESLRDYTRINLRKQYDSLDQFLQAWQQADRKAVLLQELEGQGVPLEALADEVGK
DLDPFDLLLHVAYDQPPLTRRERARRVQKRNVFTQYGPVARKVLDALLDKYADEGIATIESNEVFKLQPFTDLGSPVELV
RSFGGRPQYLSALQALEQALYATHPAH
>Mature_827_residues
MDKTKLSESDICEKFIRPAMEQAGWDGMDQIYREYPLRAGRVVVRGRQAQRDKSTVLRADYALFFKANIPLAVVEAKDNQ
HAVGAGMGQAIQYAELLGVPFSFASNGDGFVFRDATLADGVLERNLTLEEFPSPAELWSRYCAWKGWSAEESRIAGFDYA
PNKTPRYYQLNAVNRAVEAIAAGQDRVLLVMATGTGKTYTAFQIIWRLWKSGAKKRILFLADRNILIDQTMVNDFRPFKG
AMAKLSPNAKGVERVDAQGAVSVEDVDLAVNKTTKLVDKSYEIYLSLYQAVTGTEEERNIYKQFSPDFFDLIVVDECHRG
SAAEDSAWRDILTYFAGATQIGLTATPKETKDVSNTDYFGEPVYTYSLKQGIEDGYLAPYKVIRVDLDKDTFGWRPTAGM
TDKHGHAIEDRIYTGADMNRKLVLEQRDAVVAAKITEYLKATDRYAKTIVFCEDIDHAARMRQALSNANADLCATQPKYV
VQITGDNIEGKLELDNFIDPEKTYPVIATTSKLMSTGVDAQTCKLIVLDQTIKSMTLFKQIIGRGTRLREDLGKTWFTIL
DFKRATELFADKDFDGEPVQIYEPGSGQPVAPPEPAMPGDIPGDAGTPGGAANPLDPLDPLNPLGPFAGGGGAGAGPKKY
VLGNNVTVSVARERVQYLNAQGKLITESLRDYTRINLRKQYDSLDQFLQAWQQADRKAVLLQELEGQGVPLEALADEVGK
DLDPFDLLLHVAYDQPPLTRRERARRVQKRNVFTQYGPVARKVLDALLDKYADEGIATIESNEVFKLQPFTDLGSPVELV
RSFGGRPQYLSALQALEQALYATHPAH

Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG4096

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI226510991, Length=598, Percent_Identity=27.7591973244147, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1788511, Length=450, Percent_Identity=25.1111111111111, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 91886; Mature: 91886

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTKLSESDICEKFIRPAMEQAGWDGMDQIYREYPLRAGRVVVRGRQAQRDKSTVLRAD
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHEEC
YALFFKANIPLAVVEAKDNQHAVGAGMGQAIQYAELLGVPFSFASNGDGFVFRDATLADG
EEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCEEEECCHHHHH
VLERNLTLEEFPSPAELWSRYCAWKGWSAEESRIAGFDYAPNKTPRYYQLNAVNRAVEAI
HHHCCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
AAGQDRVLLVMATGTGKTYTAFQIIWRLWKSGAKKRILFLADRNILIDQTMVNDFRPFKG
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEHHHHHHCCHHHH
AMAKLSPNAKGVERVDAQGAVSVEDVDLAVNKTTKLVDKSYEIYLSLYQAVTGTEEERNI
HHHHCCCCCCCHHHHCCCCCCEEEHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YKQFSPDFFDLIVVDECHRGSAAEDSAWRDILTYFAGATQIGLTATPKETKDVSNTDYFG
HHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
EPVYTYSLKQGIEDGYLAPYKVIRVDLDKDTFGWRPTAGMTDKHGHAIEDRIYTGADMNR
CCEEEEHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCC
KLVLEQRDAVVAAKITEYLKATDRYAKTIVFCEDIDHAARMRQALSNANADLCATQPKYV
EEEEECCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCCCCCEEECCCCEE
VQITGDNIEGKLELDNFIDPEKTYPVIATTSKLMSTGVDAQTCKLIVLDQTIKSMTLFKQ
EEEECCCCCCEEEECCCCCCCCCCCEEEEHHHHHHCCCCHHHEEEEEEHHHHHHHHHHHH
IIGRGTRLREDLGKTWFTILDFKRATELFADKDFDGEPVQIYEPGSGQPVAPPEPAMPGD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
IPGDAGTPGGAANPLDPLDPLNPLGPFAGGGGAGAGPKKYVLGNNVTVSVARERVQYLNA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHHHHHCC
QGKLITESLRDYTRINLRKQYDSLDQFLQAWQQADRKAVLLQELEGQGVPLEALADEVGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCC
DLDPFDLLLHVAYDQPPLTRRERARRVQKRNVFTQYGPVARKVLDALLDKYADEGIATIE
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCCEEEC
SNEVFKLQPFTDLGSPVELVRSFGGRPQYLSALQALEQALYATHPAH
CCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKTKLSESDICEKFIRPAMEQAGWDGMDQIYREYPLRAGRVVVRGRQAQRDKSTVLRAD
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHEEC
YALFFKANIPLAVVEAKDNQHAVGAGMGQAIQYAELLGVPFSFASNGDGFVFRDATLADG
EEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCEEEECCHHHHH
VLERNLTLEEFPSPAELWSRYCAWKGWSAEESRIAGFDYAPNKTPRYYQLNAVNRAVEAI
HHHCCCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
AAGQDRVLLVMATGTGKTYTAFQIIWRLWKSGAKKRILFLADRNILIDQTMVNDFRPFKG
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEHHHHHHCCHHHH
AMAKLSPNAKGVERVDAQGAVSVEDVDLAVNKTTKLVDKSYEIYLSLYQAVTGTEEERNI
HHHHCCCCCCCHHHHCCCCCCEEEHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YKQFSPDFFDLIVVDECHRGSAAEDSAWRDILTYFAGATQIGLTATPKETKDVSNTDYFG
HHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
EPVYTYSLKQGIEDGYLAPYKVIRVDLDKDTFGWRPTAGMTDKHGHAIEDRIYTGADMNR
CCEEEEHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCC
KLVLEQRDAVVAAKITEYLKATDRYAKTIVFCEDIDHAARMRQALSNANADLCATQPKYV
EEEEECCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCCCCCEEECCCCEE
VQITGDNIEGKLELDNFIDPEKTYPVIATTSKLMSTGVDAQTCKLIVLDQTIKSMTLFKQ
EEEECCCCCCEEEECCCCCCCCCCCEEEEHHHHHHCCCCHHHEEEEEEHHHHHHHHHHHH
IIGRGTRLREDLGKTWFTILDFKRATELFADKDFDGEPVQIYEPGSGQPVAPPEPAMPGD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
IPGDAGTPGGAANPLDPLDPLNPLGPFAGGGGAGAGPKKYVLGNNVTVSVARERVQYLNA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHHHHHHHHHHCC
QGKLITESLRDYTRINLRKQYDSLDQFLQAWQQADRKAVLLQELEGQGVPLEALADEVGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCC
DLDPFDLLLHVAYDQPPLTRRERARRVQKRNVFTQYGPVARKVLDALLDKYADEGIATIE
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHCCCCEEEC
SNEVFKLQPFTDLGSPVELVRSFGGRPQYLSALQALEQALYATHPAH
CCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]