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The map label for this gene is tcp [H]

Identifier: 222110145

GI number: 222110145

Start: 954376

End: 956151

Strand: Direct

Name: tcp [H]

Synonym: Dtpsy_0931

Alternate gene names: 222110145

Gene position: 954376-956151 (Clockwise)

Preceding gene: 222110144

Following gene: 222110147

Centisome position: 25.14

GC content: 71.0

Gene sequence:

>1776_bases
ATGAGATCGCTGCGCATTTCCCACAAACTCTGGCTCGCCGTGGGCTGCATCGTGCTGGCCCAACTGACCGTCGTGGGCGT
GGCTGGTGTGCGCTCTGCCAGGGCGCAGGCCGAATCCGACGCCTTGAGCCGCGAGATGACGCAGCGCGTGCAGACGGCCA
CACGCTGGGCCGGCCTGACCGAGACCAATGCGGCCCGCACGCTGGCGCTGGTGCTCAGCACCGACGCCGTGGTGGAGCAG
GCGTTCAAGGGCGACATTGCCGCCACCTCGGCGCGCATCAGCGAACTGCAAAAGGGGCTGGAAGCCATGGCCCTCACGCC
CGCCGACCGCGAGCAGATGGGGCGCATCGCCACCGCGCGCAAGGCCATGATCGATCTGCGCAACCAGGCCCGCCAGCTCA
AGGACGCCGGCAGCCATGATGAGGCGGTGCGCCTAGCGCAGCGGTCCTACGTGCCCGCAGTGACCGCCTACCTGGGCACG
CTGCAGGAATTCGTGCGCATGCAGGAGCAGACCGCCCAGGCGCGCCAGGCAGAGATGGCCGCCACGCGCATGCTCACGGT
GAAGCTGGCGGCCGCGGCCGCAGCCATGATGCTCGCGGCCATCGTGCTAGGGGCGTATTTCCTGATCCGCAGCATCCAGC
GCCCACTGGCCGAGGCCAACGCGCTCGCGGCGCGCGTGGCGGACGGCGACCTGCGCGAGCAGGCGGTGGATGTGCAGCGC
GGCGATGAATTTGGCGAGCTGCTGCGTTCGCTGGCGGGCATGCGCGACTCGCTGGCGCGCATGGTGCAGGAGGTGCGCCA
CACCACCGACAGCATTGCCGTGGCCAGCGCGCAGATCGCCACCGGCAACCAGGACCTGTCCGCGCGCACCGAATCCACCT
CCAGCAACCTGCAGCAAACCGCCGCGGCCATGGAGGAGTTCACCAGCACCGTCCAGCACAGCGCGGCGACGGCGGGCCAG
GCCAGCCAGCTGGCCGGCGGCGCGAGCGACGTGGCGCGCCGCGGCGGCAGCGTGGTGGGGGAGGTGGTGTCCACCATGGA
CGACATCCAGCACAGCAGCCGCAAGATCGCCGACATCATCGGCGTCATCGACGGGATCGCCTTCCAGACCAACATCCTGG
CGCTGAATGCGGCCGTGGAGGCCGCGCGCGCCGGTGAGCAAGGTCGGGGCTTTGCCGTGGTGGCGGGCGAAGTGCGCAAC
CTGGCGCAGCGTTCGGCGTCGGCCGCCAAGGAGATCAAGGACCTGATCAGCGACTCGGTGGGCCGCGTGGAAAGCGGCTC
GCGCCTGGTGCACAGCGCCGGCTCCACCATGCAGGAGGTGGTGCAGTCGGTGCAGCGCGTGGCCGACATGATGGGCGAGA
TCACCGCCGCCGCCACCGAGCAAAGCGCGGGCATCTCGCAGGTGAACCAGGCCGTGGGTCAACTGGACCAGATGACGCAA
CAGAACGCGGCGCTGGTGGAGGAGAGCGCCGCCGCGGCGCAAAGCCTGCGCGAGCAGGCCGATCACCTCACGCGCGTGGT
GGCAGCATTCCGCATCGATGGCGCGGTAGCTGCTGTGCCGTCAGCCGCACGCCCCGTGCCGGCCGCTCCACAGGCACGTC
CCATGCCGGTGGCACCTGTGGGCAAGGCACCCGCCGCGCCCCGCGCGGCGGCAGCGCCGGCACGGGCGCCGGCGCAGCGT
GTGGCGGCCCCCCTGCGTGCGGCTGCTGCACCTGCCGCCGCCGCACGGCCTGCGGCACTGGCCCAAGGTGGTGAGGACGA
TTGGGAGTCCTTCTGA

Upstream 100 bases:

>100_bases
TTTTGATAGCGATAGTATGTCGCGTGGGCGGCGGGGCTTCTTTGTTGCGTTTGGTAGCATTCTCGCAACCCCGCCATAAC
GAATTCCAGGAGCCCACCCC

Downstream 100 bases:

>100_bases
TCCGCGTGCGGTCGCACGCCTTGCGCTGACGGGGCGCCTTGCTTGCCACGCGGGCGCGCGGGGCTGGCTCCTTCACCTCC
CGCATGCCGCGACGAGCGCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MRSLRISHKLWLAVGCIVLAQLTVVGVAGVRSARAQAESDALSREMTQRVQTATRWAGLTETNAARTLALVLSTDAVVEQ
AFKGDIAATSARISELQKGLEAMALTPADREQMGRIATARKAMIDLRNQARQLKDAGSHDEAVRLAQRSYVPAVTAYLGT
LQEFVRMQEQTAQARQAEMAATRMLTVKLAAAAAAMMLAAIVLGAYFLIRSIQRPLAEANALAARVADGDLREQAVDVQR
GDEFGELLRSLAGMRDSLARMVQEVRHTTDSIAVASAQIATGNQDLSARTESTSSNLQQTAAAMEEFTSTVQHSAATAGQ
ASQLAGGASDVARRGGSVVGEVVSTMDDIQHSSRKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRN
LAQRSASAAKEIKDLISDSVGRVESGSRLVHSAGSTMQEVVQSVQRVADMMGEITAAATEQSAGISQVNQAVGQLDQMTQ
QNAALVEESAAAAQSLREQADHLTRVVAAFRIDGAVAAVPSAARPVPAAPQARPMPVAPVGKAPAAPRAAAAPARAPAQR
VAAPLRAAAAPAAAARPAALAQGGEDDWESF

Sequences:

>Translated_591_residues
MRSLRISHKLWLAVGCIVLAQLTVVGVAGVRSARAQAESDALSREMTQRVQTATRWAGLTETNAARTLALVLSTDAVVEQ
AFKGDIAATSARISELQKGLEAMALTPADREQMGRIATARKAMIDLRNQARQLKDAGSHDEAVRLAQRSYVPAVTAYLGT
LQEFVRMQEQTAQARQAEMAATRMLTVKLAAAAAAMMLAAIVLGAYFLIRSIQRPLAEANALAARVADGDLREQAVDVQR
GDEFGELLRSLAGMRDSLARMVQEVRHTTDSIAVASAQIATGNQDLSARTESTSSNLQQTAAAMEEFTSTVQHSAATAGQ
ASQLAGGASDVARRGGSVVGEVVSTMDDIQHSSRKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRN
LAQRSASAAKEIKDLISDSVGRVESGSRLVHSAGSTMQEVVQSVQRVADMMGEITAAATEQSAGISQVNQAVGQLDQMTQ
QNAALVEESAAAAQSLREQADHLTRVVAAFRIDGAVAAVPSAARPVPAAPQARPMPVAPVGKAPAAPRAAAAPARAPAQR
VAAPLRAAAAPAAAARPAALAQGGEDDWESF
>Mature_591_residues
MRSLRISHKLWLAVGCIVLAQLTVVGVAGVRSARAQAESDALSREMTQRVQTATRWAGLTETNAARTLALVLSTDAVVEQ
AFKGDIAATSARISELQKGLEAMALTPADREQMGRIATARKAMIDLRNQARQLKDAGSHDEAVRLAQRSYVPAVTAYLGT
LQEFVRMQEQTAQARQAEMAATRMLTVKLAAAAAAMMLAAIVLGAYFLIRSIQRPLAEANALAARVADGDLREQAVDVQR
GDEFGELLRSLAGMRDSLARMVQEVRHTTDSIAVASAQIATGNQDLSARTESTSSNLQQTAAAMEEFTSTVQHSAATAGQ
ASQLAGGASDVARRGGSVVGEVVSTMDDIQHSSRKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRN
LAQRSASAAKEIKDLISDSVGRVESGSRLVHSAGSTMQEVVQSVQRVADMMGEITAAATEQSAGISQVNQAVGQLDQMTQ
QNAALVEESAAAAQSLREQADHLTRVVAAFRIDGAVAAVPSAARPVPAAPQARPMPVAPVGKAPAAPRAAAAPARAPAQR
VAAPLRAAAAPAAAARPAALAQGGEDDWESF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=345, Percent_Identity=55.3623188405797, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI2367378, Length=345, Percent_Identity=55.9420289855072, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788194, Length=320, Percent_Identity=52.1875, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1787690, Length=457, Percent_Identity=42.4507658643326, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=40.9230769230769, Blast_Score=224, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 61618; Mature: 61618

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLRISHKLWLAVGCIVLAQLTVVGVAGVRSARAQAESDALSREMTQRVQTATRWAGLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETNAARTLALVLSTDAVVEQAFKGDIAATSARISELQKGLEAMALTPADREQMGRIATAR
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KAMIDLRNQARQLKDAGSHDEAVRLAQRSYVPAVTAYLGTLQEFVRMQEQTAQARQAEMA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATRMLTVKLAAAAAAMMLAAIVLGAYFLIRSIQRPLAEANALAARVADGDLREQAVDVQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GDEFGELLRSLAGMRDSLARMVQEVRHTTDSIAVASAQIATGNQDLSARTESTSSNLQQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AAAMEEFTSTVQHSAATAGQASQLAGGASDVARRGGSVVGEVVSTMDDIQHSSRKIADII
HHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSASAAKEIKDLISDSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVESGSRLVHSAGSTMQEVVQSVQRVADMMGEITAAATEQSAGISQVNQAVGQLDQMTQ
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QNAALVEESAAAAQSLREQADHLTRVVAAFRIDGAVAAVPSAARPVPAAPQARPMPVAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCC
GKAPAAPRAAAAPARAPAQRVAAPLRAAAAPAAAARPAALAQGGEDDWESF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MRSLRISHKLWLAVGCIVLAQLTVVGVAGVRSARAQAESDALSREMTQRVQTATRWAGLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETNAARTLALVLSTDAVVEQAFKGDIAATSARISELQKGLEAMALTPADREQMGRIATAR
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KAMIDLRNQARQLKDAGSHDEAVRLAQRSYVPAVTAYLGTLQEFVRMQEQTAQARQAEMA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATRMLTVKLAAAAAAMMLAAIVLGAYFLIRSIQRPLAEANALAARVADGDLREQAVDVQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GDEFGELLRSLAGMRDSLARMVQEVRHTTDSIAVASAQIATGNQDLSARTESTSSNLQQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AAAMEEFTSTVQHSAATAGQASQLAGGASDVARRGGSVVGEVVSTMDDIQHSSRKIADII
HHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSASAAKEIKDLISDSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GRVESGSRLVHSAGSTMQEVVQSVQRVADMMGEITAAATEQSAGISQVNQAVGQLDQMTQ
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QNAALVEESAAAAQSLREQADHLTRVVAAFRIDGAVAAVPSAARPVPAAPQARPMPVAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCC
GKAPAAPRAAAAPARAPAQRVAAPLRAAAAPAAAARPAALAQGGEDDWESF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]