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The map label for this gene is aphA [H]

Identifier: 222109832

GI number: 222109832

Start: 635626

End: 636396

Strand: Direct

Name: aphA [H]

Synonym: Dtpsy_0616

Alternate gene names: 222109832

Gene position: 635626-636396 (Clockwise)

Preceding gene: 222109831

Following gene: 222109836

Centisome position: 16.74

GC content: 71.73

Gene sequence:

>771_bases
ATGACCGGCGAGGGCATTCCACCGGCGGACACGCTGGCGCAACTGCGCAGCGAACTGGCCCAGGCGCGCCAGCAGATCAG
CGATATGGCGGCGGCGCAGGAGGACTTTCTACGGGGTGTGTCGCACGACCTGCGCGCGCCGCTGCGCCACGTCACCTCTT
ATGGCGCGCTGGTGCGCGAGGTACTACAGGAGCAGCCGCCGCAGGTGGACGAGGCGCTGGGTTTCCTGGCCACGATGGAG
CAGTCCGCGCGCCGCATGGCGCAGATGATCGACGGGCTGCAGGCCATCGCCCGCGCACGCAGCGCTGCGCTGCGGCCCCG
GGCCGTTGCGCTGACCGCGGCTGTGCAGGAGGCTCGGCAGGCTTTGGGTGCGGCGGCCGAAGGCGCGGCATGGAACATTG
CGCCGGATCTGCCCGTCGTGCAGGCCGATCCCGAGCTGCTGGCCCAGTTGCTGGTGCAACTGCTGGGCAATGCGGTGAAG
TTCTCGCGCGGCGTGGCGCAGCCCCGTGTGCAGGTGCAGGCTGAACCTGCGGCGCCGGGCGGTGTGCGCATCACCGTGCG
GGACAACGGCGTGGGCTTTGATGGCACGCGCGCGCAGCAGCTCTTTGGCGTGTTCCAGCGCATGCACCGCGAAGCCGAAT
TCGAGGGCGTGGGCGCGGGTCTCGCGCTGTGCCAGGCGATCGCGCAGCGCCATGGCGCCCACATCCAGGCCACCGCGGTG
CCCGGTGCGGGCTGCACGGTGGCGCTGGAGTGGCCGGCTGCGGCGCGGTAG

Upstream 100 bases:

>100_bases
ACCAAGGACACGCCACCCGGGGGGTTGAGCGTGGCGCGTGGCCGGCAGGTGAGCATCGCGAACTGGAAGCGCCCCGCCAA
ACAGGCCAAGGGTTGAGGCC

Downstream 100 bases:

>100_bases
CGGCCTGCGCTTGCCGCGCTTCCCGCCGCGCTCAAGGCATCGCCGCAGGCAGGCCCAGGCGCGTCTGCAGCTCGCGCAGG
CGCTGGCGCAGCGCGGTCAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTGEGIPPADTLAQLRSELAQARQQISDMAAAQEDFLRGVSHDLRAPLRHVTSYGALVREVLQEQPPQVDEALGFLATME
QSARRMAQMIDGLQAIARARSAALRPRAVALTAAVQEARQALGAAAEGAAWNIAPDLPVVQADPELLAQLLVQLLGNAVK
FSRGVAQPRVQVQAEPAAPGGVRITVRDNGVGFDGTRAQQLFGVFQRMHREAEFEGVGAGLALCQAIAQRHGAHIQATAV
PGAGCTVALEWPAAAR

Sequences:

>Translated_256_residues
MTGEGIPPADTLAQLRSELAQARQQISDMAAAQEDFLRGVSHDLRAPLRHVTSYGALVREVLQEQPPQVDEALGFLATME
QSARRMAQMIDGLQAIARARSAALRPRAVALTAAVQEARQALGAAAEGAAWNIAPDLPVVQADPELLAQLLVQLLGNAVK
FSRGVAQPRVQVQAEPAAPGGVRITVRDNGVGFDGTRAQQLFGVFQRMHREAEFEGVGAGLALCQAIAQRHGAHIQATAV
PGAGCTVALEWPAAAR
>Mature_255_residues
TGEGIPPADTLAQLRSELAQARQQISDMAAAQEDFLRGVSHDLRAPLRHVTSYGALVREVLQEQPPQVDEALGFLATMEQ
SARRMAQMIDGLQAIARARSAALRPRAVALTAAVQEARQALGAAAEGAAWNIAPDLPVVQADPELLAQLLVQLLGNAVKF
SRGVAQPRVQVQAEPAAPGGVRITVRDNGVGFDGTRAQQLFGVFQRMHREAEFEGVGAGLALCQAIAQRHGAHIQATAVP
GAGCTVALEWPAAAR

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=28.8, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789149, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=27.4774774774775, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=29.3577981651376, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=23.7885462555066, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=27.6785714285714, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=23.6, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 27036; Mature: 26905

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEGIPPADTLAQLRSELAQARQQISDMAAAQEDFLRGVSHDLRAPLRHVTSYGALVRE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLQEQPPQVDEALGFLATMEQSARRMAQMIDGLQAIARARSAALRPRAVALTAAVQEARQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALGAAAEGAAWNIAPDLPVVQADPELLAQLLVQLLGNAVKFSRGVAQPRVQVQAEPAAPG
HHCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
GVRITVRDNGVGFDGTRAQQLFGVFQRMHREAEFEGVGAGLALCQAIAQRHGAHIQATAV
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEC
PGAGCTVALEWPAAAR
CCCCCEEEECCCCCCC
>Mature Secondary Structure 
TGEGIPPADTLAQLRSELAQARQQISDMAAAQEDFLRGVSHDLRAPLRHVTSYGALVRE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLQEQPPQVDEALGFLATMEQSARRMAQMIDGLQAIARARSAALRPRAVALTAAVQEARQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALGAAAEGAAWNIAPDLPVVQADPELLAQLLVQLLGNAVKFSRGVAQPRVQVQAEPAAPG
HHCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
GVRITVRDNGVGFDGTRAQQLFGVFQRMHREAEFEGVGAGLALCQAIAQRHGAHIQATAV
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEC
PGAGCTVALEWPAAAR
CCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]