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The map label for this gene is erpA

Identifier: 222109824

GI number: 222109824

Start: 627285

End: 627659

Strand: Direct

Name: erpA

Synonym: Dtpsy_0608

Alternate gene names: 222109824

Gene position: 627285-627659 (Clockwise)

Preceding gene: 222109823

Following gene: 222109827

Centisome position: 16.52

GC content: 58.13

Gene sequence:

>375_bases
ATGAGCGCCGTTGCCGAGAACACCACGACCGAGATGCCCGCCCCCATCCTTTTCACCGACAGCGCCGCCGCCAAGGTGGC
CGAGCTGATTGCCGAAGAAGGCAATCCTGACCTCAAGCTGCGGGTCTTCGTGCAGGGCGGGGGATGCTCGGGCTTCCAGT
ATGGTTTCACATTTGATGAAATCACGAACGAAGACGACACCACCATGACCAAGAACGGTGTGTCACTGCTCATCGATGCC
ATGAGCTACCAATACTTGGTGGGTGCAGAGATCGACTACAAGGAAGACCTGCAGGGTGCGCAGTTCGTCATCAAGAACCC
GAATGCCGCTTCGACATGCGGCTGCGGCTCCAGCTTCTCCGTGGAAGACCACTGA

Upstream 100 bases:

>100_bases
AGAAAAGCCCACACTGAAACTGGCGTCAAACGCACAGTGAACGGAGCGCTGGGGGGCTATGCCTTACCATCGAAACAAAG
ACTGACCCAAGGAGCCCTTC

Downstream 100 bases:

>100_bases
CGCACAGCCCATGAGAATCCGCCGCCTACGGGCGGCTTTTTTATGGCTGCGTGGCAGGTTGCTCAGGCGGGGTAGATGGC
GCCGAGGATGCGCTCCCCGC

Product: iron-sulfur cluster insertion protein erpa

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MSAVAENTTTEMPAPILFTDSAAAKVAELIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDA
MSYQYLVGAEIDYKEDLQGAQFVIKNPNAASTCGCGSSFSVEDH

Sequences:

>Translated_124_residues
MSAVAENTTTEMPAPILFTDSAAAKVAELIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDA
MSYQYLVGAEIDYKEDLQGAQFVIKNPNAASTCGCGSSFSVEDH
>Mature_123_residues
SAVAENTTTEMPAPILFTDSAAAKVAELIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDAM
SYQYLVGAEIDYKEDLQGAQFVIKNPNAASTCGCGSSFSVEDH

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=108, Percent_Identity=39.8148148148148, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI52426768, Length=122, Percent_Identity=31.1475409836066, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=62.1621621621622, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=35.8490566037736, Blast_Score=70, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=38.8888888888889, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=112, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=111, Percent_Identity=29.7297297297297, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=36.7924528301887, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=84, Percent_Identity=47.6190476190476, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642263, Length=122, Percent_Identity=31.1475409836066, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_ACISJ (A1W3Q0)

Other databases:

- EMBL:   CP000539
- RefSeq:   YP_984951.1
- ProteinModelPortal:   A1W3Q0
- SMR:   A1W3Q0
- STRING:   A1W3Q0
- GeneID:   4674259
- GenomeReviews:   CP000539_GR
- KEGG:   ajs:Ajs_0629
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   A1W3Q0
- ProtClustDB:   PRK13623
- BioCyc:   ASP232721:AJS_0629-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13234; Mature: 13103

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVAENTTTEMPAPILFTDSAAAKVAELIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHH
ITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNAASTCGCGSSFS
HCCCCCCEEECCCCEEEEECCCCEEEECCCCCCHHCCCCCEEEEECCCCCCCCCCCCCCC
VEDH
CCCC
>Mature Secondary Structure 
SAVAENTTTEMPAPILFTDSAAAKVAELIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDE
CCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHH
ITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNAASTCGCGSSFS
HCCCCCCEEECCCCEEEEECCCCEEEECCCCCCHHCCCCCEEEEECCCCCCCCCCCCCCC
VEDH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA