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The map label for this gene is tlyA [H]

Identifier: 222109814

GI number: 222109814

Start: 618627

End: 619625

Strand: Direct

Name: tlyA [H]

Synonym: Dtpsy_0598

Alternate gene names: 222109814

Gene position: 618627-619625 (Clockwise)

Preceding gene: 222109813

Following gene: 222109815

Centisome position: 16.29

GC content: 68.17

Gene sequence:

>999_bases
ATGCGCGCGGACGTATTTCTGGTGGAAGGCGGCTACGCGGCCACCCGGTCGCAGGCCCAGCGGTTGATTGCCGCCGGCGT
GCAGTGGCGCCTGGCGCCCACGCTGCCGTGGCAGAAGGTGGCCAAGAACGGCGACGACATTCCCGCGGGGGTCGAGGTGC
AGCTGCTGGACGCTGCGGAGGCCAAGTACCTCTCGCGCGGCGGCCTCAAGCTTGAAGGTGCGCTGGCGGCCACGGGCCTG
CAAGTGGCTGGCCTGCGCTGCCTGGACGTGGGGCAGAGCACCGGCGGTTTCACCGACTGCCTGCTGGCACATGGCGCTGC
CCAGGTGATTGGCGTGGACGTGGGCCACGGCCAGTTGCACGAGCGGCTGCGCGCCGACCCGCGGGTGGTCTGCGTGGAAG
GCGTGAATGCCCGTGCCCTCACGCCCGAGGCGTTGCAGGACGCCTGCGACGTGGCGCTGTCCGAAGTCATCGAGGACGTG
GAAGACAACGACACCCAGCCCCAGGCCCCCTACGCCTGGATGCGCAACGGCGGCATGGTGGACGATGAGTACGACGACAG
CGACGACGCCAAGGAGCATGAGATCGAGAGCTTCAAGGCTGAGCGCGCCGCCAAGGCCAAGGCACGCGCCGATGGCTCAT
TGCCCGTGCAGCGCCGCCGCCGCCCCGGGTGCGAGGACGTGGACATCACGCCAGCGTTCGATCTCGTCACCGGCGACCTG
TCCTTCATCTCGCTCACGCTGGTGCTGCCTGCGCTGGTGCCGCTGTTGAAAGAGCAGGGCCAGCTGCTGATGCTGGTCAA
GCCGCAGTTTGAGTTGCAACCCGGCCAAGTGGGCAAGGGCGGCATCGTGCGCGATGCGCAGCTGTATCCGCAGGTGGAGC
AGCGCATCCGTGACTGCTGCACGGAGCTGGGGCTGCACGTGGTGGCCTGGATCGATAGCCCCATCGAGGGGGGCGACGGC
AACCGCGAGTTCTTCATCCATGCAAGGAGGAAGGCATGA

Upstream 100 bases:

>100_bases
ATAGCTGCTTGCGCTTGCCAGTAGCCGTTTTCAGTATGAAATATTGCTGAAAATGGCTCACTGCAAGCGCTGCCAGCTAT
CGATATGAGAGGAAAGCGCG

Downstream 100 bases:

>100_bases
GCCTTTCCACGGCCTTTCCGGTCAGCTTTGAATTCTTCCCGCCCAAGACGCCCGAGGGCGCCGACAAACTGCGCGCCGTG
CGCCAGCAGCTGTATGCCCG

Product: ribosomal RNA methyltransferase rrmj/ftsj

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRADVFLVEGGYAATRSQAQRLIAAGVQWRLAPTLPWQKVAKNGDDIPAGVEVQLLDAAEAKYLSRGGLKLEGALAATGL
QVAGLRCLDVGQSTGGFTDCLLAHGAAQVIGVDVGHGQLHERLRADPRVVCVEGVNARALTPEALQDACDVALSEVIEDV
EDNDTQPQAPYAWMRNGGMVDDEYDDSDDAKEHEIESFKAERAAKAKARADGSLPVQRRRRPGCEDVDITPAFDLVTGDL
SFISLTLVLPALVPLLKEQGQLLMLVKPQFELQPGQVGKGGIVRDAQLYPQVEQRIRDCCTELGLHVVAWIDSPIEGGDG
NREFFIHARRKA

Sequences:

>Translated_332_residues
MRADVFLVEGGYAATRSQAQRLIAAGVQWRLAPTLPWQKVAKNGDDIPAGVEVQLLDAAEAKYLSRGGLKLEGALAATGL
QVAGLRCLDVGQSTGGFTDCLLAHGAAQVIGVDVGHGQLHERLRADPRVVCVEGVNARALTPEALQDACDVALSEVIEDV
EDNDTQPQAPYAWMRNGGMVDDEYDDSDDAKEHEIESFKAERAAKAKARADGSLPVQRRRRPGCEDVDITPAFDLVTGDL
SFISLTLVLPALVPLLKEQGQLLMLVKPQFELQPGQVGKGGIVRDAQLYPQVEQRIRDCCTELGLHVVAWIDSPIEGGDG
NREFFIHARRKA
>Mature_332_residues
MRADVFLVEGGYAATRSQAQRLIAAGVQWRLAPTLPWQKVAKNGDDIPAGVEVQLLDAAEAKYLSRGGLKLEGALAATGL
QVAGLRCLDVGQSTGGFTDCLLAHGAAQVIGVDVGHGQLHERLRADPRVVCVEGVNARALTPEALQDACDVALSEVIEDV
EDNDTQPQAPYAWMRNGGMVDDEYDDSDDAKEHEIESFKAERAAKAKARADGSLPVQRRRRPGCEDVDITPAFDLVTGDL
SFISLTLVLPALVPLLKEQGQLLMLVKPQFELQPGQVGKGGIVRDAQLYPQVEQRIRDCCTELGLHVVAWIDSPIEGGDG
NREFFIHARRKA

Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 35892; Mature: 35892

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADVFLVEGGYAATRSQAQRLIAAGVQWRLAPTLPWQKVAKNGDDIPAGVEVQLLDAAE
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCEEEEECHHH
AKYLSRGGLKLEGALAATGLQVAGLRCLDVGQSTGGFTDCLLAHGAAQVIGVDVGHGQLH
HHHHHCCCCEEECHHHHCCHHHHCEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCHHHH
ERLRADPRVVCVEGVNARALTPEALQDACDVALSEVIEDVEDNDTQPQAPYAWMRNGGMV
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
DDEYDDSDDAKEHEIESFKAERAAKAKARADGSLPVQRRRRPGCEDVDITPAFDLVTGDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCHHHEECCH
SFISLTLVLPALVPLLKEQGQLLMLVKPQFELQPGQVGKGGIVRDAQLYPQVEQRIRDCC
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHH
TELGLHVVAWIDSPIEGGDGNREFFIHARRKA
HHCCCEEEEEECCCCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MRADVFLVEGGYAATRSQAQRLIAAGVQWRLAPTLPWQKVAKNGDDIPAGVEVQLLDAAE
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCEEEEECHHH
AKYLSRGGLKLEGALAATGLQVAGLRCLDVGQSTGGFTDCLLAHGAAQVIGVDVGHGQLH
HHHHHCCCCEEECHHHHCCHHHHCEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCHHHH
ERLRADPRVVCVEGVNARALTPEALQDACDVALSEVIEDVEDNDTQPQAPYAWMRNGGMV
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
DDEYDDSDDAKEHEIESFKAERAAKAKARADGSLPVQRRRRPGCEDVDITPAFDLVTGDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCHHHEECCH
SFISLTLVLPALVPLLKEQGQLLMLVKPQFELQPGQVGKGGIVRDAQLYPQVEQRIRDCC
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHH
TELGLHVVAWIDSPIEGGDGNREFFIHARRKA
HHCCCEEEEEECCCCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730486 [H]