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The map label for this gene is prpL [H]

Identifier: 222109712

GI number: 222109712

Start: 509345

End: 510811

Strand: Direct

Name: prpL [H]

Synonym: Dtpsy_0494

Alternate gene names: 222109712

Gene position: 509345-510811 (Clockwise)

Preceding gene: 222109711

Following gene: 222109716

Centisome position: 13.42

GC content: 69.67

Gene sequence:

>1467_bases
ATGCAATTACTGACAACAACTGCGGCGCAATGGGCCGCGATACCCCTGGTGCTGGCCTTGTCCGCTTGCGGTGGAGGTGG
CGGCGGCAACGACACTCCCTCTCCTACGCCTCCGGTGGCGGGCGACCGCATCGAGCCCTACGACCCCAGCGGCACGGCCA
AGGTGGCCACCTCGCAGCAGGCGGTGAGCCCGGTCGCCAGTGCACAGGCAACCCGCACCATCGCCCTCGGCGCGCTCACG
GCCGTGAAGGGCGTGGTCTCCGCCACTCCCGGAACGCCCTTGCAGATCGGCGAGGCGCGCAGCGTGGCGGACACCGCCAC
CGTCGCGGCCACTGCGGCCCTGCTGCGCTGGCAACCGACGGCGCGGGGCACGCAGGCCGCTGCGCTGCGCTTCACGGCCG
ACGGAGCGCATGGCGTGCGTCTGGGCGTGCTCGTGCAGTCGCTGCCCGAGGGCGCGGTGCTGCGCTTCTACGGCGAGCAG
GGCGCGGGGGCCATGGAGGTGCGCGCGTCCGAGCTGCAGGACATCGCCGCGCGCAATGCGCGTGGCGGTGCGGATGACAC
CACCGCGCGCACCTATTGGAGCCCGGACTTCAGCGGCCCGCAAACCACACTGGAAGTGGAGATTCCCGCTGCGGCCTCGC
CAGCGGCCGTCCGACTGTCCGTGCCGCGGCTGTCGCATTTCACGCTGGCGCCCGCACAGGCCGAGCAGGCCCTTGCCCAG
AAGGTGGGCGAGTCGGGCAGCTGCAACGTGGACGCGACCTGCCGGCCGGAGTTCAACGACCAGAGCCGCTCGGTGGCGCG
CATGATCTTTGTGCGCGACGATGGCAAGAGCTACCTGTGCACCGGCACGCTGCTCAACGATGCGGCGTCCAGCGGTACGC
CCTACTTCCTGAGCGCCAACCATTGCATTTCCACGCAGGCCGTGGCGTCCACGCTCACCACGGACTGGTTCTACCGTTCC
AGCACCTGCGGCACCGCCACGGTGAACCCCGCCGCCGTGCGCGTCACCGGCGGTGCGGCGCTGCTGTACGCGTCGGCCAC
CACGGACACGGCCTTCATGCAGCTCAACAGCCAGGCGCCTGCCGGCATCGTCTATGCAGGCTCGTACTTTGGCGGAGTGG
GCGTTGGCACGGCGCTGGCGGGTGTGCACCATCCCCAGGGCGATCTGCAGAAGGTCAGCCTGGGCTCCATGCAGCGCTAC
AGCACGTGCGTCGACAACAGTTGCCGTTCCAGTAATGCGGACGACGGCACCTTCCTAACGCTGGGCTGGCAGGAGGGGAC
GACCGAAGGCGGCAGCAGCGGCTCGGCCGCGTTCGTGACGTTTGGCGAACGTCGCTATGTGGTGGGCCAGCTTCTGGGCG
GAACCGCCAGCTGCGCTGCGCGCGACGGCGTGGACTATTACGGTCGTTTCGACACCAGCTACCGCACGGCGCTGCGGCGC
TGGCTGAATCCGACGGCGGCCAACTAA

Upstream 100 bases:

>100_bases
GCTGCGCTCAAGGCGCTGCCGGCGGATGTGGGAGTGAGCGAGGGGATCAAGCTGGCGCTGAAATCGCTATCCAAATAGTT
CTTACGTAGAGGAGAGAGCA

Downstream 100 bases:

>100_bases
CCCACCAGCACCAGCCCGGGCGGCAGGCTGTCGCCCAGGCTGCGCTGCTGGTCCTCGGCCTCCATGGCCGTGGGCTGTTC
CACCAGCGCGATCCAGCGTG

Product: endoproteinase arg-c

Products: NA

Alternate protein names: Protease IV; pvdS-regulated endoprotease [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MQLLTTTAAQWAAIPLVLALSACGGGGGGNDTPSPTPPVAGDRIEPYDPSGTAKVATSQQAVSPVASAQATRTIALGALT
AVKGVVSATPGTPLQIGEARSVADTATVAATAALLRWQPTARGTQAAALRFTADGAHGVRLGVLVQSLPEGAVLRFYGEQ
GAGAMEVRASELQDIAARNARGGADDTTARTYWSPDFSGPQTTLEVEIPAAASPAAVRLSVPRLSHFTLAPAQAEQALAQ
KVGESGSCNVDATCRPEFNDQSRSVARMIFVRDDGKSYLCTGTLLNDAASSGTPYFLSANHCISTQAVASTLTTDWFYRS
STCGTATVNPAAVRVTGGAALLYASATTDTAFMQLNSQAPAGIVYAGSYFGGVGVGTALAGVHHPQGDLQKVSLGSMQRY
STCVDNSCRSSNADDGTFLTLGWQEGTTEGGSSGSAAFVTFGERRYVVGQLLGGTASCAARDGVDYYGRFDTSYRTALRR
WLNPTAAN

Sequences:

>Translated_488_residues
MQLLTTTAAQWAAIPLVLALSACGGGGGGNDTPSPTPPVAGDRIEPYDPSGTAKVATSQQAVSPVASAQATRTIALGALT
AVKGVVSATPGTPLQIGEARSVADTATVAATAALLRWQPTARGTQAAALRFTADGAHGVRLGVLVQSLPEGAVLRFYGEQ
GAGAMEVRASELQDIAARNARGGADDTTARTYWSPDFSGPQTTLEVEIPAAASPAAVRLSVPRLSHFTLAPAQAEQALAQ
KVGESGSCNVDATCRPEFNDQSRSVARMIFVRDDGKSYLCTGTLLNDAASSGTPYFLSANHCISTQAVASTLTTDWFYRS
STCGTATVNPAAVRVTGGAALLYASATTDTAFMQLNSQAPAGIVYAGSYFGGVGVGTALAGVHHPQGDLQKVSLGSMQRY
STCVDNSCRSSNADDGTFLTLGWQEGTTEGGSSGSAAFVTFGERRYVVGQLLGGTASCAARDGVDYYGRFDTSYRTALRR
WLNPTAAN
>Mature_488_residues
MQLLTTTAAQWAAIPLVLALSACGGGGGGNDTPSPTPPVAGDRIEPYDPSGTAKVATSQQAVSPVASAQATRTIALGALT
AVKGVVSATPGTPLQIGEARSVADTATVAATAALLRWQPTARGTQAAALRFTADGAHGVRLGVLVQSLPEGAVLRFYGEQ
GAGAMEVRASELQDIAARNARGGADDTTARTYWSPDFSGPQTTLEVEIPAAASPAAVRLSVPRLSHFTLAPAQAEQALAQ
KVGESGSCNVDATCRPEFNDQSRSVARMIFVRDDGKSYLCTGTLLNDAASSGTPYFLSANHCISTQAVASTLTTDWFYRS
STCGTATVNPAAVRVTGGAALLYASATTDTAFMQLNSQAPAGIVYAGSYFGGVGVGTALAGVHHPQGDLQKVSLGSMQRY
STCVDNSCRSSNADDGTFLTLGWQEGTTEGGSSGSAAFVTFGERRYVVGQLLGGTASCAARDGVDYYGRFDTSYRTALRR
WLNPTAAN

Specific function: Lysine-specific endoprotease. Involved in corneal virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003 [H]

Pfam domain/function: NA

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 50174; Mature: 50174

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLTTTAAQWAAIPLVLALSACGGGGGGNDTPSPTPPVAGDRIEPYDPSGTAKVATSQQ
CCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHH
AVSPVASAQATRTIALGALTAVKGVVSATPGTPLQIGEARSVADTATVAATAALLRWQPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
ARGTQAAALRFTADGAHGVRLGVLVQSLPEGAVLRFYGEQGAGAMEVRASELQDIAARNA
CCCCCEEEEEEECCCCCCEEHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHCC
RGGADDTTARTYWSPDFSGPQTTLEVEIPAAASPAAVRLSVPRLSHFTLAPAQAEQALAQ
CCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEEECHHHHHHHHHH
KVGESGSCNVDATCRPEFNDQSRSVARMIFVRDDGKSYLCTGTLLNDAASSGTPYFLSAN
HCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCEEEEEEEEHHHCCCCCCCEEEECC
HCISTQAVASTLTTDWFYRSSTCGTATVNPAAVRVTGGAALLYASATTDTAFMQLNSQAP
CCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCEEEEEEECCCCEEEEEECCCCC
AGIVYAGSYFGGVGVGTALAGVHHPQGDLQKVSLGSMQRYSTCVDNSCRSSNADDGTFLT
CCEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCEEEE
LGWQEGTTEGGSSGSAAFVTFGERRYVVGQLLGGTASCAARDGVDYYGRFDTSYRTALRR
EECCCCCCCCCCCCCEEEEEECCCEEEEHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHH
WLNPTAAN
HCCCCCCC
>Mature Secondary Structure
MQLLTTTAAQWAAIPLVLALSACGGGGGGNDTPSPTPPVAGDRIEPYDPSGTAKVATSQQ
CCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHH
AVSPVASAQATRTIALGALTAVKGVVSATPGTPLQIGEARSVADTATVAATAALLRWQPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCC
ARGTQAAALRFTADGAHGVRLGVLVQSLPEGAVLRFYGEQGAGAMEVRASELQDIAARNA
CCCCCEEEEEEECCCCCCEEHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHCC
RGGADDTTARTYWSPDFSGPQTTLEVEIPAAASPAAVRLSVPRLSHFTLAPAQAEQALAQ
CCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEEECHHHHHHHHHH
KVGESGSCNVDATCRPEFNDQSRSVARMIFVRDDGKSYLCTGTLLNDAASSGTPYFLSAN
HCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCEEEEEEEEHHHCCCCCCCEEEECC
HCISTQAVASTLTTDWFYRSSTCGTATVNPAAVRVTGGAALLYASATTDTAFMQLNSQAP
CCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCEEEEEEECCCCEEEEEECCCCC
AGIVYAGSYFGGVGVGTALAGVHHPQGDLQKVSLGSMQRYSTCVDNSCRSSNADDGTFLT
CCEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCEEEE
LGWQEGTTEGGSSGSAAFVTFGERRYVVGQLLGGTASCAARDGVDYYGRFDTSYRTALRR
EECCCCCCCCCCCCCEEEEEECCCEEEEHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHH
WLNPTAAN
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12419815; 10984043 [H]