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The map label for this gene is ruvA [H]

Identifier: 222109711

GI number: 222109711

Start: 508750

End: 509322

Strand: Direct

Name: ruvA [H]

Synonym: Dtpsy_0493

Alternate gene names: 222109711

Gene position: 508750-509322 (Clockwise)

Preceding gene: 222109707

Following gene: 222109712

Centisome position: 13.4

GC content: 65.62

Gene sequence:

>573_bases
ATGATAGGCAAATTGACCGGCACGCTGCTGGAAAAGAACCCCCCCGAGGTGCTGGTGGACTGCCACGGCGTGGGCTACGA
GGTGCTGGTCAGCATGAGCACCTTCTACAACCTGCCCGCCGTGGGTGAGCGGGTGAGCCTGCTCACGCAGTTCATCGTGC
GCGAGGATGCGCAGCTGCTGTACGGCTTTGGTACGGCGCAGGAGCGCCAGGCGTTTCGCGAACTCATCAAGATCAGCGGC
GTGGGGCCGCGCACAGCGCTGTCCATCCTCTCGGGCATGGGCGTGGCGGACCTGGCGCAGGCCGTTTCGCTGCAGGAAGC
AGGGCGCCTGGTCAAAGTGCCGGGTATCGGCAAGAAAACCGCCGAGCGGCTGCTGCTGGAGCTGAAAGGCAAGCTGGGCG
CGGACGTCGGCGTGCGCGCGCATGCGGCCAACGACAACCAGGCCGACATCCTGCAGGCGCTGCTGGCCCTGGGCTATAAC
GACAAGGAGGCCGCCGCTGCGCTCAAGGCGCTGCCGGCGGATGTGGGAGTGAGCGAGGGGATCAAGCTGGCGCTGAAATC
GCTATCCAAATAG

Upstream 100 bases:

>100_bases
AGGCGCGTGTTGTTATGGGGGGTGAAGGTGTGGCGCAGGATCACGCTGATAATTCCGGTCGAAGTTCCGCGGCGGGTGTC
CGGCGCGGCAAAGGACATCC

Downstream 100 bases:

>100_bases
TTCTTACGTAGAGGAGAGAGCAATGCAATTACTGACAACAACTGCGGCGCAATGGGCCGCGATACCCCTGGTGCTGGCCT
TGTCCGCTTGCGGTGGAGGT

Product: holliday junction DNA helicase ruva

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIGKLTGTLLEKNPPEVLVDCHGVGYEVLVSMSTFYNLPAVGERVSLLTQFIVREDAQLLYGFGTAQERQAFRELIKISG
VGPRTALSILSGMGVADLAQAVSLQEAGRLVKVPGIGKKTAERLLLELKGKLGADVGVRAHAANDNQADILQALLALGYN
DKEAAAALKALPADVGVSEGIKLALKSLSK

Sequences:

>Translated_190_residues
MIGKLTGTLLEKNPPEVLVDCHGVGYEVLVSMSTFYNLPAVGERVSLLTQFIVREDAQLLYGFGTAQERQAFRELIKISG
VGPRTALSILSGMGVADLAQAVSLQEAGRLVKVPGIGKKTAERLLLELKGKLGADVGVRAHAANDNQADILQALLALGYN
DKEAAAALKALPADVGVSEGIKLALKSLSK
>Mature_190_residues
MIGKLTGTLLEKNPPEVLVDCHGVGYEVLVSMSTFYNLPAVGERVSLLTQFIVREDAQLLYGFGTAQERQAFRELIKISG
VGPRTALSILSGMGVADLAQAVSLQEAGRLVKVPGIGKKTAERLLLELKGKLGADVGVRAHAANDNQADILQALLALGYN
DKEAAAALKALPADVGVSEGIKLALKSLSK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=178, Percent_Identity=48.876404494382, Blast_Score=169, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20006; Mature: 20006

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLTGTLLEKNPPEVLVDCHGVGYEVLVSMSTFYNLPAVGERVSLLTQFIVREDAQLL
CCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
YGFGTAQERQAFRELIKISGVGPRTALSILSGMGVADLAQAVSLQEAGRLVKVPGIGKKT
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCHHH
AERLLLELKGKLGADVGVRAHAANDNQADILQALLALGYNDKEAAAALKALPADVGVSEG
HHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHH
IKLALKSLSK
HHHHHHHHCC
>Mature Secondary Structure
MIGKLTGTLLEKNPPEVLVDCHGVGYEVLVSMSTFYNLPAVGERVSLLTQFIVREDAQLL
CCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
YGFGTAQERQAFRELIKISGVGPRTALSILSGMGVADLAQAVSLQEAGRLVKVPGIGKKT
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCHHH
AERLLLELKGKLGADVGVRAHAANDNQADILQALLALGYNDKEAAAALKALPADVGVSEG
HHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHH
IKLALKSLSK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA