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The map label for this gene is recG [H]

Identifier: 222109587

GI number: 222109587

Start: 378027

End: 380198

Strand: Direct

Name: recG [H]

Synonym: Dtpsy_0367

Alternate gene names: 222109587

Gene position: 378027-380198 (Clockwise)

Preceding gene: 222109583

Following gene: 222109588

Centisome position: 9.96

GC content: 70.76

Gene sequence:

>2172_bases
GTGCCCAGACCCACACGTTCCTCCACCTCCGCCTCGTCCTCCGCGAAGCCCGCCCCCAGCCCCGCACAGCAGGCCCTCGT
CAAGCTGGGGCTGGTGCGCGACATCGACCTGGCCCTGCACCTGCCCCTGCGCTACGAGGACGAGACGCGCATCACGCCGA
TCCGCAGCGCACGCGATGGCGACACGGTGCAGATCGAGGCCACGGTGACCGCCAGCGAGGTGCAGATGCGCCCGCGCCGG
CAACTGGTGGTGACCGTGGAGGACGGCACCGGCAGCTGCGAGCTGCGCTTCTTCAGCTTCTACCCTTCGCACCAGAAGAC
CATGGCCGTGGGCGCGCGCCTGCGCGTGCGCGGCGAAATCAAGGGAGGCTTCTGGGGCCGCCAGATGCTGCACCCGGCGT
TCCGCAAGGCCGAAGGGGACTTGCCCGCGGCTCTGACCCCCGTCTATCCCACGGTGGCGCAGCTGCCTCAGGCGTACCTG
CGCCGCGCCGTGGCGAGCGCCCTCACGCGCGTGGAATTGCCCGAGACGCTGCCGCCGGGGCTCGAGCCCCCCGCGGTTCC
CTCATGGGTGCGGGGGAATGGCCAAAATGGCCTACTGCGCCCATGGAGCCTGCGCGAGGCGCTCCTTTTTTTGCATCACC
CCGCGCCCGATGTGGCGCTGGCCACGCTGCAGGACCACAGTCACCCGGCGTGGCAGCGCCTGAAGGCCGAGGAACTGCTG
GCGCAGCAGCTGTCGCAACTCACCGCCAAGCGCGAGCGCGCCCGCCTGCGTGCCCCGGCCCTGCGCCCGCAGGCGCAGGC
GGGAAGCACGCCGCTGCACGAGCAATTGCTGGGCGTGTTGCCCTTCAGCCTGACGGCCGCGCAGCGCCGCGTGGGTGAGG
AGATCGCGCGCGATCTGGCCCGGCCGGTGCCCATGCACCGTTTGCTGCAGGGCGACGTGGGCTCGGGCAAGACCGTGGTG
GCCGCGCTGGCCGCCACGGTGTGCATGGACGCGGGCTGGCAGTGCGCGCTGATGGCGCCCACCGAGATCCTGGCCGAGCA
GCACTTCGCCAAGCTCATCGGCTGGCTGCAGCCGCTGCTGGCCGCGCGCGGGCGCCAGGTGGCGTGGCTGGTGGGCGGAC
AGAAGAAGAAAGAGCGCGCCGAGATGCTCGCGCGCATCGAAAGCGGCGAGGCCGCGCTGGTCGTGGGCACGCACGCCGTC
ATCCAGGAGCAGGTGCGTTTCAAGAACCTGGCGCTGGCGGTGATCGATGAGCAGCACCGCTTCGGCGTGGCACAACGCCT
GGCGCTGCGCAAAAAGCTGCAGCACGCCGGCATGGAGCCGCACCTGCTGATGATGAGTGCCACGCCCATCCCGCGCACGC
TGGCCATGAGTTACTACGCCGATCTGGACGTGTCCACCATCGACGAGCTGCCGCCCGGGCGCACGCCCATCGTCACCAAG
CTGATCGCGGACAGCCGCAAGGATGAGGTGGTCGAGCGCATCGGTGCGCAGGTGGCGGCGGGCCGGCAGGTGTACTGGGT
GTGCCCGCTGATCGAGGAGAGCGAGGCGCTGGACCTGTCCAACGCCACCGCCACGCACGCCGAGTTGAGCGAGGCGTTGC
AGGGCGACGCGGCGCACGGGCGCGCGCCCGTGATGGTGGGCCTGCTGCACTCGCGCATGCCCGCCGCCGAGAAGAAAGCC
GTGATGGACCTGTTCAAGGGCGGGCAGATGGGCGTGCTGGTGTCCACCACCGTGATCGAAGTGGGCGTGGACGTGCCCAA
CGCCTCGCTCATGGTCATCGAGCATGCAGAGCGCTTCGGCCTGTCGCAGCTGCACCAGTTGCGCGGGCGCGTGGGGCGCG
GCGCGGCGGCTTCGGCCTGCGTGCTGCTGTACTCCACGGGCGATTCGGGCCGCCTGGGCGAGACCGCGCGCGACCGCCTG
AAGGCCATGGCCGAGACCACCGACGGTTTCGAGATCGCGCGGCGCGACCTGGAGATCCGCGGGCCCGGCGAGTTCCTGGG
CGCTCGCCAGTCGGGCGACGCACTGCTGCGCTTTGCCGACCTGGCCACCGATACGCTGCTGCTGGAATGGGCGCGCGAGA
CGGCGCCGCAGATGCTGGATCGCCACCCGCTGCTGGCCGAGCGCCACATCCAGCGCTGGCTTGGCGGAAAATCGGACTAT
CTCAAAGCCTGA

Upstream 100 bases:

>100_bases
CATGCCCAGGGTGAGATGCTTGACTTCGATGCGCTTGAGCATGACGGGAGACGACGAGACGGTAACGTGCGGTAACTGCG
GGCATGGTAGCCTTTTTGCC

Downstream 100 bases:

>100_bases
TGGGCCGCCCGTGGCCGCATAGCGCGGCGGGCGTTGCACAATGGCCGATTCTGCCGGCCGGATTCGCCATGACTCTTACC
GAACTCAAATACATCGTCGC

Product: ATP-dependent DNA helicase recg

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MPRPTRSSTSASSSAKPAPSPAQQALVKLGLVRDIDLALHLPLRYEDETRITPIRSARDGDTVQIEATVTASEVQMRPRR
QLVVTVEDGTGSCELRFFSFYPSHQKTMAVGARLRVRGEIKGGFWGRQMLHPAFRKAEGDLPAALTPVYPTVAQLPQAYL
RRAVASALTRVELPETLPPGLEPPAVPSWVRGNGQNGLLRPWSLREALLFLHHPAPDVALATLQDHSHPAWQRLKAEELL
AQQLSQLTAKRERARLRAPALRPQAQAGSTPLHEQLLGVLPFSLTAAQRRVGEEIARDLARPVPMHRLLQGDVGSGKTVV
AALAATVCMDAGWQCALMAPTEILAEQHFAKLIGWLQPLLAARGRQVAWLVGGQKKKERAEMLARIESGEAALVVGTHAV
IQEQVRFKNLALAVIDEQHRFGVAQRLALRKKLQHAGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTK
LIADSRKDEVVERIGAQVAAGRQVYWVCPLIEESEALDLSNATATHAELSEALQGDAAHGRAPVMVGLLHSRMPAAEKKA
VMDLFKGGQMGVLVSTTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGAAASACVLLYSTGDSGRLGETARDRL
KAMAETTDGFEIARRDLEIRGPGEFLGARQSGDALLRFADLATDTLLLEWARETAPQMLDRHPLLAERHIQRWLGGKSDY
LKA

Sequences:

>Translated_723_residues
MPRPTRSSTSASSSAKPAPSPAQQALVKLGLVRDIDLALHLPLRYEDETRITPIRSARDGDTVQIEATVTASEVQMRPRR
QLVVTVEDGTGSCELRFFSFYPSHQKTMAVGARLRVRGEIKGGFWGRQMLHPAFRKAEGDLPAALTPVYPTVAQLPQAYL
RRAVASALTRVELPETLPPGLEPPAVPSWVRGNGQNGLLRPWSLREALLFLHHPAPDVALATLQDHSHPAWQRLKAEELL
AQQLSQLTAKRERARLRAPALRPQAQAGSTPLHEQLLGVLPFSLTAAQRRVGEEIARDLARPVPMHRLLQGDVGSGKTVV
AALAATVCMDAGWQCALMAPTEILAEQHFAKLIGWLQPLLAARGRQVAWLVGGQKKKERAEMLARIESGEAALVVGTHAV
IQEQVRFKNLALAVIDEQHRFGVAQRLALRKKLQHAGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTK
LIADSRKDEVVERIGAQVAAGRQVYWVCPLIEESEALDLSNATATHAELSEALQGDAAHGRAPVMVGLLHSRMPAAEKKA
VMDLFKGGQMGVLVSTTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGAAASACVLLYSTGDSGRLGETARDRL
KAMAETTDGFEIARRDLEIRGPGEFLGARQSGDALLRFADLATDTLLLEWARETAPQMLDRHPLLAERHIQRWLGGKSDY
LKA
>Mature_722_residues
PRPTRSSTSASSSAKPAPSPAQQALVKLGLVRDIDLALHLPLRYEDETRITPIRSARDGDTVQIEATVTASEVQMRPRRQ
LVVTVEDGTGSCELRFFSFYPSHQKTMAVGARLRVRGEIKGGFWGRQMLHPAFRKAEGDLPAALTPVYPTVAQLPQAYLR
RAVASALTRVELPETLPPGLEPPAVPSWVRGNGQNGLLRPWSLREALLFLHHPAPDVALATLQDHSHPAWQRLKAEELLA
QQLSQLTAKRERARLRAPALRPQAQAGSTPLHEQLLGVLPFSLTAAQRRVGEEIARDLARPVPMHRLLQGDVGSGKTVVA
ALAATVCMDAGWQCALMAPTEILAEQHFAKLIGWLQPLLAARGRQVAWLVGGQKKKERAEMLARIESGEAALVVGTHAVI
QEQVRFKNLALAVIDEQHRFGVAQRLALRKKLQHAGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTKL
IADSRKDEVVERIGAQVAAGRQVYWVCPLIEESEALDLSNATATHAELSEALQGDAAHGRAPVMVGLLHSRMPAAEKKAV
MDLFKGGQMGVLVSTTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGAAASACVLLYSTGDSGRLGETARDRLK
AMAETTDGFEIARRDLEIRGPGEFLGARQSGDALLRFADLATDTLLLEWARETAPQMLDRHPLLAERHIQRWLGGKSDYL
KA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=709, Percent_Identity=48.3779971791255, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1787357, Length=402, Percent_Identity=36.81592039801, Blast_Score=218, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78944; Mature: 78813

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPTRSSTSASSSAKPAPSPAQQALVKLGLVRDIDLALHLPLRYEDETRITPIRSARDG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCEEEECCEEECCCCCCCCCCCCCCC
DTVQIEATVTASEVQMRPRRQLVVTVEDGTGSCELRFFSFYPSHQKTMAVGARLRVRGEI
CEEEEEEEEEHHHHHCCCCEEEEEEEECCCCCEEEEEEEECCCCCHHHHHCCEEEEEEEC
KGGFWGRQMLHPAFRKAEGDLPAALTPVYPTVAQLPQAYLRRAVASALTRVELPETLPPG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LEPPAVPSWVRGNGQNGLLRPWSLREALLFLHHPAPDVALATLQDHSHPAWQRLKAEELL
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHCCCCHHHHHHHHHHHH
AQQLSQLTAKRERARLRAPALRPQAQAGSTPLHEQLLGVLPFSLTAAQRRVGEEIARDLA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
RPVPMHRLLQGDVGSGKTVVAALAATVCMDAGWQCALMAPTEILAEQHFAKLIGWLQPLL
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
AARGRQVAWLVGGQKKKERAEMLARIESGEAALVVGTHAVIQEQVRFKNLALAVIDEQHR
HHCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHEEEEEECCHHH
FGVAQRLALRKKLQHAGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTK
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCHHHHH
LIADSRKDEVVERIGAQVAAGRQVYWVCPLIEESEALDLSNATATHAELSEALQGDAAHG
HHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
RAPVMVGLLHSRMPAAEKKAVMDLFKGGQMGVLVSTTVIEVGVDVPNASLMVIEHAERFG
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCEEEEECHHHCC
LSQLHQLRGRVGRGAAASACVLLYSTGDSGRLGETARDRLKAMAETTDGFEIARRDLEIR
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCEEC
GPGEFLGARQSGDALLRFADLATDTLLLEWARETAPQMLDRHPLLAERHIQRWLGGKSDY
CCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
LKA
CCC
>Mature Secondary Structure 
PRPTRSSTSASSSAKPAPSPAQQALVKLGLVRDIDLALHLPLRYEDETRITPIRSARDG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCEEEECCEEECCCCCCCCCCCCCCC
DTVQIEATVTASEVQMRPRRQLVVTVEDGTGSCELRFFSFYPSHQKTMAVGARLRVRGEI
CEEEEEEEEEHHHHHCCCCEEEEEEEECCCCCEEEEEEEECCCCCHHHHHCCEEEEEEEC
KGGFWGRQMLHPAFRKAEGDLPAALTPVYPTVAQLPQAYLRRAVASALTRVELPETLPPG
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LEPPAVPSWVRGNGQNGLLRPWSLREALLFLHHPAPDVALATLQDHSHPAWQRLKAEELL
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEHHCCCCHHHHHHHHHHHH
AQQLSQLTAKRERARLRAPALRPQAQAGSTPLHEQLLGVLPFSLTAAQRRVGEEIARDLA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
RPVPMHRLLQGDVGSGKTVVAALAATVCMDAGWQCALMAPTEILAEQHFAKLIGWLQPLL
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
AARGRQVAWLVGGQKKKERAEMLARIESGEAALVVGTHAVIQEQVRFKNLALAVIDEQHR
HHCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHEEEEEECCHHH
FGVAQRLALRKKLQHAGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTK
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCHHHHH
LIADSRKDEVVERIGAQVAAGRQVYWVCPLIEESEALDLSNATATHAELSEALQGDAAHG
HHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
RAPVMVGLLHSRMPAAEKKAVMDLFKGGQMGVLVSTTVIEVGVDVPNASLMVIEHAERFG
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCEEEEECHHHCC
LSQLHQLRGRVGRGAAASACVLLYSTGDSGRLGETARDRLKAMAETTDGFEIARRDLEIR
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCEEC
GPGEFLGARQSGDALLRFADLATDTLLLEWARETAPQMLDRHPLLAERHIQRWLGGKSDY
CCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
LKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]