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The map label for this gene is oxyR [H]

Identifier: 222109588

GI number: 222109588

Start: 380267

End: 381232

Strand: Direct

Name: oxyR [H]

Synonym: Dtpsy_0368

Alternate gene names: 222109588

Gene position: 380267-381232 (Clockwise)

Preceding gene: 222109587

Following gene: 222109589

Centisome position: 10.02

GC content: 67.29

Gene sequence:

>966_bases
ATGACTCTTACCGAACTCAAATACATCGTCGCCGTTGCGCGTGAAAAACACTTCGGCCGCGCCGCCGAAGCCTGCTATGT
CTCGCAGCCCACGCTGTCGGTAGCGGTGAAGAAGCTCGAGGACGAGCTGGAGGTCAAGCTCTTCGAGCGCAGCGCGGGCG
ATGTCTCCGTCACGCCGCTGGGCGAGGAAATCGTGCGACAGGCGCAGAGCGTGCTGGAGCAGGCTGCCGCCATCAAGGAG
ATCGCCAAGCGCGGCAAGGACCCGCTGGCCGGCGCCCTCACGCTGGGCGTGATCTACACCATCGGCCCCTACCTGCTGCC
CGAGCTGGTGCGCCATGCCATCGCGCGCACGCCGCAGATGCCGCTGATGCTGCAGGAGAACTTCACCGTGAAGCTGCTGG
AGATGCTGCGCACCGGGGAGATCGACTGCGCCATCATGGCCGAGCCCTTCCCCGACACCGGCCTGGCCATCGCGCCGCTG
TATGACGAACCCTTCCTGGCGGCCGTGCCCAGCAGCCACCCGCTGGCCGAGCGCGATGCTGTCTCGGCGTCGGAACTCAA
GAACGAAACCATGCTGCTGCTGGGTGCGGGCCACTGCTTTCGCGACCACGTGCTGGAGGTGTGCCCTGAGTTCGCGCGCT
ACGCGAGCAATGCCGAAGGCATTCGCCGCACGTTCGAAGGCTCGTCGCTGGAGACCATCAAGCACATGGTCTCCGCCGGC
ATGGGCGTGACGCTGGTGCCGCGCCTGTCGGTGCCGCGGGATGCGCTGCACACGGGTGCACGCCGGCGCAAGAGCGACGA
CACGCACATCCGCTACCTGCCCATCAAGGAGAGCGACGGCAGCCCGCCGCCCATGCGCCGCGTGGTGCTGGCCTGGAGGC
GCAGCTTCACGCGCTACGAGGCCATCGCCGCGCTGCGCAACGCTGTCTACGCCTGCGAGTTGCCCGGCGTCACGCGCTTG
TCTTGA

Upstream 100 bases:

>100_bases
TTGGCGGAAAATCGGACTATCTCAAAGCCTGATGGGCCGCCCGTGGCCGCATAGCGCGGCGGGCGTTGCACAATGGCCGA
TTCTGCCGGCCGGATTCGCC

Downstream 100 bases:

>100_bases
CGCAGGGCGATGCTGCGCGGCGCGGCAGTTGGTACAGTCATGGCAGAGTCATCCCAACCACCCAGAAAGGACGCACCATG
GCCAAGCCCAGCAGCAAATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTLTELKYIVAVAREKHFGRAAEACYVSQPTLSVAVKKLEDELEVKLFERSAGDVSVTPLGEEIVRQAQSVLEQAAAIKE
IAKRGKDPLAGALTLGVIYTIGPYLLPELVRHAIARTPQMPLMLQENFTVKLLEMLRTGEIDCAIMAEPFPDTGLAIAPL
YDEPFLAAVPSSHPLAERDAVSASELKNETMLLLGAGHCFRDHVLEVCPEFARYASNAEGIRRTFEGSSLETIKHMVSAG
MGVTLVPRLSVPRDALHTGARRRKSDDTHIRYLPIKESDGSPPPMRRVVLAWRRSFTRYEAIAALRNAVYACELPGVTRL
S

Sequences:

>Translated_321_residues
MTLTELKYIVAVAREKHFGRAAEACYVSQPTLSVAVKKLEDELEVKLFERSAGDVSVTPLGEEIVRQAQSVLEQAAAIKE
IAKRGKDPLAGALTLGVIYTIGPYLLPELVRHAIARTPQMPLMLQENFTVKLLEMLRTGEIDCAIMAEPFPDTGLAIAPL
YDEPFLAAVPSSHPLAERDAVSASELKNETMLLLGAGHCFRDHVLEVCPEFARYASNAEGIRRTFEGSSLETIKHMVSAG
MGVTLVPRLSVPRDALHTGARRRKSDDTHIRYLPIKESDGSPPPMRRVVLAWRRSFTRYEAIAALRNAVYACELPGVTRL
S
>Mature_320_residues
TLTELKYIVAVAREKHFGRAAEACYVSQPTLSVAVKKLEDELEVKLFERSAGDVSVTPLGEEIVRQAQSVLEQAAAIKEI
AKRGKDPLAGALTLGVIYTIGPYLLPELVRHAIARTPQMPLMLQENFTVKLLEMLRTGEIDCAIMAEPFPDTGLAIAPLY
DEPFLAAVPSSHPLAERDAVSASELKNETMLLLGAGHCFRDHVLEVCPEFARYASNAEGIRRTFEGSSLETIKHMVSAGM
GVTLVPRLSVPRDALHTGARRRKSDDTHIRYLPIKESDGSPPPMRRVVLAWRRSFTRYEAIAALRNAVYACELPGVTRLS

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=306, Percent_Identity=38.8888888888889, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787530, Length=256, Percent_Identity=30.859375, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI157672245, Length=235, Percent_Identity=31.4893617021277, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788887, Length=255, Percent_Identity=30.1960784313725, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=30.8, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788748, Length=257, Percent_Identity=26.8482490272374, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693105, Length=253, Percent_Identity=26.4822134387352, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=27.6450511945392, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=29.3706293706294, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=24.4979919678715, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788481, Length=264, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=249, Percent_Identity=27.710843373494, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87081904, Length=179, Percent_Identity=29.608938547486, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=252, Percent_Identity=24.2063492063492, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082132, Length=255, Percent_Identity=23.921568627451, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=22.5806451612903, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786401, Length=163, Percent_Identity=33.7423312883436, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35344; Mature: 35213

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTELKYIVAVAREKHFGRAAEACYVSQPTLSVAVKKLEDELEVKLFERSAGDVSVTPL
CCHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GEEIVRQAQSVLEQAAAIKEIAKRGKDPLAGALTLGVIYTIGPYLLPELVRHAIARTPQM
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLMLQENFTVKLLEMLRTGEIDCAIMAEPFPDTGLAIAPLYDEPFLAAVPSSHPLAERDA
CEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCEEECCCCCCCCHHHC
VSASELKNETMLLLGAGHCFRDHVLEVCPEFARYASNAEGIRRTFEGSSLETIKHMVSAG
CCHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCC
MGVTLVPRLSVPRDALHTGARRRKSDDTHIRYLPIKESDGSPPPMRRVVLAWRRSFTRYE
CCEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AIAALRNAVYACELPGVTRLS
HHHHHHHHHEEECCCCCCCCC
>Mature Secondary Structure 
TLTELKYIVAVAREKHFGRAAEACYVSQPTLSVAVKKLEDELEVKLFERSAGDVSVTPL
CHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GEEIVRQAQSVLEQAAAIKEIAKRGKDPLAGALTLGVIYTIGPYLLPELVRHAIARTPQM
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLMLQENFTVKLLEMLRTGEIDCAIMAEPFPDTGLAIAPLYDEPFLAAVPSSHPLAERDA
CEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCEEECCCCCCCCHHHC
VSASELKNETMLLLGAGHCFRDHVLEVCPEFARYASNAEGIRRTFEGSSLETIKHMVSAG
CCHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCC
MGVTLVPRLSVPRDALHTGARRRKSDDTHIRYLPIKESDGSPPPMRRVVLAWRRSFTRYE
CCEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AIAALRNAVYACELPGVTRLS
HHHHHHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA