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The map label for this gene is hisK [H]

Identifier: 222102856

GI number: 222102856

Start: 533454

End: 534329

Strand: Reverse

Name: hisK [H]

Synonym: Avi_7588

Alternate gene names: 222102856

Gene position: 534329-533454 (Counterclockwise)

Preceding gene: 222102857

Following gene: 222102855

Centisome position: 84.58

GC content: 57.99

Gene sequence:

>876_bases
ATGACCTGGTTTAGTTATCACGGTGGCCATAGCGGGCAGTTCTGCGACCATGCGAAATCCACTCTTGCCGACGTGATCGA
GACGGCAATCGACCGCGGCTTTACCCATTACGGGTTGAGCGAACACTGCCCGCGGTATCGGGATGAAGATCTCTATCCCG
GTGAAGAAAGGTTGGGCGTCGCAGGCCTTGCGCGCCAGTTCGCCGACTATGTCGATCACGCATTCAAGCTTCGTGACGCC
TATGCGGACCGGATCGAGTTGCTGATCGGTTTTGAGACCGAGAAATTGCCGCCGGATACATGGCTTGCCAAGATGGAGGC
CATACGGAACGCGCATCCGTTCGACTACATTGTTGGCAGCGTCCACGATATCGAAGGTTGCTGGCTCGACTATTCCGCGC
AAGCGACCGAGACCCTCAAGAGCGAGCTGGGCGGCACCGACGCGCTACAGATCGCCTATTTCCAATCGGCGACCGACATG
GTGGAACGCCTTCGTCCAGATGTCGTTGCGCATCTCGATCTCGTCAGGAAGTATGAACCGGCAGGCTTTGAATTTTCCGA
CAAGGTTTTGCGTGAGGTGGACACCCTTCTCGAAGCGATCAAGGCCTATGGCGGCATAGTGGATGTGAATTGTGCCGCCT
TCCGCAATGGCTTCGGCCCGGTTTACCCGCTGCCGCACATACTCAACCGTGCCCGCCATATGGGCATCCGCGTGACGCTG
GGTGATGACAGCCACGGCGTGGACACCGTCGGCGTTGGGCTTGAGCAGTCAGTCGCCGCAATCCGAGCCGCTGGCTTTGA
GAGCATTGCCTATCTGACGCGTTCCAATGGATGGCTCCAGGCGGACATAGACGATGTCGCACCCGGAAAAATCTGA

Upstream 100 bases:

>100_bases
GGTCGAATTCATTGATATCGACGGGCTGATGAAGAGCTATATCGAAGATTACAACGGCTCGATTTATCGCTCGCCTGCGA
AAACGGCCTGAGGACAAGCT

Downstream 100 bases:

>100_bases
GGGCGGCGCGATGCCAGCACTTCATGCGCTTGCCATCCGGCCCGCAACCCCGAATGACATCGATTTCGTCATGCGTGTCG
AACGGCTCCCCGGCTATCCA

Product: hypothetical protein

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTWFSYHGGHSGQFCDHAKSTLADVIETAIDRGFTHYGLSEHCPRYRDEDLYPGEERLGVAGLARQFADYVDHAFKLRDA
YADRIELLIGFETEKLPPDTWLAKMEAIRNAHPFDYIVGSVHDIEGCWLDYSAQATETLKSELGGTDALQIAYFQSATDM
VERLRPDVVAHLDLVRKYEPAGFEFSDKVLREVDTLLEAIKAYGGIVDVNCAAFRNGFGPVYPLPHILNRARHMGIRVTL
GDDSHGVDTVGVGLEQSVAAIRAAGFESIAYLTRSNGWLQADIDDVAPGKI

Sequences:

>Translated_291_residues
MTWFSYHGGHSGQFCDHAKSTLADVIETAIDRGFTHYGLSEHCPRYRDEDLYPGEERLGVAGLARQFADYVDHAFKLRDA
YADRIELLIGFETEKLPPDTWLAKMEAIRNAHPFDYIVGSVHDIEGCWLDYSAQATETLKSELGGTDALQIAYFQSATDM
VERLRPDVVAHLDLVRKYEPAGFEFSDKVLREVDTLLEAIKAYGGIVDVNCAAFRNGFGPVYPLPHILNRARHMGIRVTL
GDDSHGVDTVGVGLEQSVAAIRAAGFESIAYLTRSNGWLQADIDDVAPGKI
>Mature_290_residues
TWFSYHGGHSGQFCDHAKSTLADVIETAIDRGFTHYGLSEHCPRYRDEDLYPGEERLGVAGLARQFADYVDHAFKLRDAY
ADRIELLIGFETEKLPPDTWLAKMEAIRNAHPFDYIVGSVHDIEGCWLDYSAQATETLKSELGGTDALQIAYFQSATDMV
ERLRPDVVAHLDLVRKYEPAGFEFSDKVLREVDTLLEAIKAYGGIVDVNCAAFRNGFGPVYPLPHILNRARHMGIRVTLG
DDSHGVDTVGVGLEQSVAAIRAAGFESIAYLTRSNGWLQADIDDVAPGKI

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321138, Length=312, Percent_Identity=28.525641025641, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 32297; Mature: 32165

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWFSYHGGHSGQFCDHAKSTLADVIETAIDRGFTHYGLSEHCPRYRDEDLYPGEERLGV
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
AGLARQFADYVDHAFKLRDAYADRIELLIGFETEKLPPDTWLAKMEAIRNAHPFDYIVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
VHDIEGCWLDYSAQATETLKSELGGTDALQIAYFQSATDMVERLRPDVVAHLDLVRKYEP
HHCCCCCEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
AGFEFSDKVLREVDTLLEAIKAYGGIVDVNCAAFRNGFGPVYPLPHILNRARHMGIRVTL
CCCCHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHCCCCCCCCHHHHHHHHHHCCEEEEE
GDDSHGVDTVGVGLEQSVAAIRAAGFESIAYLTRSNGWLQADIDDVAPGKI
CCCCCCCCHHCCCHHHHHHHHHHHCHHHHHHHHCCCCEEEECHHCCCCCCC
>Mature Secondary Structure 
TWFSYHGGHSGQFCDHAKSTLADVIETAIDRGFTHYGLSEHCPRYRDEDLYPGEERLGV
CEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
AGLARQFADYVDHAFKLRDAYADRIELLIGFETEKLPPDTWLAKMEAIRNAHPFDYIVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
VHDIEGCWLDYSAQATETLKSELGGTDALQIAYFQSATDMVERLRPDVVAHLDLVRKYEP
HHCCCCCEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
AGFEFSDKVLREVDTLLEAIKAYGGIVDVNCAAFRNGFGPVYPLPHILNRARHMGIRVTL
CCCCHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHCCCCCCCCHHHHHHHHHHCCEEEEE
GDDSHGVDTVGVGLEQSVAAIRAAGFESIAYLTRSNGWLQADIDDVAPGKI
CCCCCCCCHHCCCHHHHHHHHHHHCHHHHHHHHCCCCEEEECHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]