Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 222102745

GI number: 222102745

Start: 399505

End: 400440

Strand: Direct

Name: ycgM [C]

Synonym: Avi_7430

Alternate gene names: 222102745

Gene position: 399505-400440 (Clockwise)

Preceding gene: 222102744

Following gene: 222102746

Centisome position: 63.24

GC content: 55.98

Gene sequence:

>936_bases
ATGAAACTTGCATTTTTCGATTCCTACAAACTTGGCGTCGTGCGAGGTGACGTCATCATCGACGTTTCGTCCGCAGTCGA
GACAATTGCGCATGTGGGGCCACACGACCTCATGCAAGGATTGATCGAGCGGTTTGATGAGTTTCGCAGCGCGTTGGAAG
CCGCTGCAGACGCTGGTGAGCCGATCAGCTTGGCATCGGTTGCGCTGCGAGCGCCTCTGCCGAAGCCCAGCAATATCGTC
TGCATGGCCGTGAACTACATGGAGGACGGAACACTTGCGGAGCCGCCCGCCATCAATGCGTTCCACAAGGCACCAACGGC
TGTCATTGGGCCGGGCGGAACCATGGTCCTGCCTGACATTCCCGCAAGGACCTTTGAAGGGGAAGCTGAGATGGCCTTGG
TGATCGGCAAGCGTGCGCATCAGGTTTCTGCTGAAAACTGGCGCGACTATGTTTTCGGTTACGTGAATTTCATCGATGGT
TCGGCGCGTGGCACCCTCCCTGAAAAGAACAATTATTTTCAGATGAAATCGCGTGACACGTTTGCCCCGATTGGTCCCTG
GATAGTCACCGCCGATGAAATCCCGGATCCGCAATCCTTGCAGGTTCGCCTTTGGGTCAATGGCACGCTCAAGCAGGATT
TCAACACCGATGACATGGCGCACAAGATCCCGCGTTGCATTGAGTGGCTAAGCCATATCCAGGTTTTGGAGCCGGGCGAT
GTTGTGGCCACAGGCACAAATCACCGGGGTCTCAATGCACTTCAGGATGGAGATAGCGTAGAGTTGGAAATCGAAGGTCT
TGGCCGGCTTGCGATCAATGTGCGCGATGACCTGAAGAGAACCTGGCCACGCGACACACGTGTTGAGCTTATGGCCAAAG
GCGTGAAGGGCCCAGCCGTTCAACTGACAGGCAAACACGCGCCCGTCAGCCCATGA

Upstream 100 bases:

>100_bases
CGAGGCACTGGATTCTGTCCGGCTCAGATTGAGCCGGACAGAGTCTAGGAAGCCGGGTTCCATTTTATCCTCGATAAACT
CTAGCTTAGAGATCATCTTC

Downstream 100 bases:

>100_bases
TTTGATCAGGGGAGGGAGGTGGGGCACCTTGCACACCTTCCCTTCGGTGATTAGCGTGCATTTTTTTGGTCGAGTCTCTC
TGCGTGGGATAGGTGCGTCG

Product: fumarylacetoacetate (FAA) hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKLAFFDSYKLGVVRGDVIIDVSSAVETIAHVGPHDLMQGLIERFDEFRSALEAAADAGEPISLASVALRAPLPKPSNIV
CMAVNYMEDGTLAEPPAINAFHKAPTAVIGPGGTMVLPDIPARTFEGEAEMALVIGKRAHQVSAENWRDYVFGYVNFIDG
SARGTLPEKNNYFQMKSRDTFAPIGPWIVTADEIPDPQSLQVRLWVNGTLKQDFNTDDMAHKIPRCIEWLSHIQVLEPGD
VVATGTNHRGLNALQDGDSVELEIEGLGRLAINVRDDLKRTWPRDTRVELMAKGVKGPAVQLTGKHAPVSP

Sequences:

>Translated_311_residues
MKLAFFDSYKLGVVRGDVIIDVSSAVETIAHVGPHDLMQGLIERFDEFRSALEAAADAGEPISLASVALRAPLPKPSNIV
CMAVNYMEDGTLAEPPAINAFHKAPTAVIGPGGTMVLPDIPARTFEGEAEMALVIGKRAHQVSAENWRDYVFGYVNFIDG
SARGTLPEKNNYFQMKSRDTFAPIGPWIVTADEIPDPQSLQVRLWVNGTLKQDFNTDDMAHKIPRCIEWLSHIQVLEPGD
VVATGTNHRGLNALQDGDSVELEIEGLGRLAINVRDDLKRTWPRDTRVELMAKGVKGPAVQLTGKHAPVSP
>Mature_311_residues
MKLAFFDSYKLGVVRGDVIIDVSSAVETIAHVGPHDLMQGLIERFDEFRSALEAAADAGEPISLASVALRAPLPKPSNIV
CMAVNYMEDGTLAEPPAINAFHKAPTAVIGPGGTMVLPDIPARTFEGEAEMALVIGKRAHQVSAENWRDYVFGYVNFIDG
SARGTLPEKNNYFQMKSRDTFAPIGPWIVTADEIPDPQSLQVRLWVNGTLKQDFNTDDMAHKIPRCIEWLSHIQVLEPGD
VVATGTNHRGLNALQDGDSVELEIEGLGRLAINVRDDLKRTWPRDTRVELMAKGVKGPAVQLTGKHAPVSP

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=243, Percent_Identity=32.0987654320988, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI156231349, Length=243, Percent_Identity=31.6872427983539, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=32.3671497584541, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=32.3529411764706, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=33, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=30.1507537688442, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=32.4742268041237, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=37.5, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24663695, Length=224, Percent_Identity=30.3571428571429, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=32.1951219512195, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33926; Mature: 33926

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAFFDSYKLGVVRGDVIIDVSSAVETIAHVGPHDLMQGLIERFDEFRSALEAAADAGE
CEEEEECCCEEEEEECCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PISLASVALRAPLPKPSNIVCMAVNYMEDGTLAEPPAINAFHKAPTAVIGPGGTMVLPDI
CHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHCCCCEEECCCCEEEECCC
PARTFEGEAEMALVIGKRAHQVSAENWRDYVFGYVNFIDGSARGTLPEKNNYFQMKSRDT
CCCCCCCCCCEEEEECCHHHHCCHHHHHHHEEEEEEEECCCCCCCCCCCCCEEEECCCCC
FAPIGPWIVTADEIPDPQSLQVRLWVNGTLKQDFNTDDMAHKIPRCIEWLSHIQVLEPGD
CCCCCCEEEEECCCCCCCCEEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHCEEECCCC
VVATGTNHRGLNALQDGDSVELEIEGLGRLAINVRDDLKRTWPRDTRVELMAKGVKGPAV
EEEECCCCCCCCHHCCCCEEEEEEEECCEEEEEEHHHHHHHCCCCCHHHHHHCCCCCCEE
QLTGKHAPVSP
EEECCCCCCCC
>Mature Secondary Structure
MKLAFFDSYKLGVVRGDVIIDVSSAVETIAHVGPHDLMQGLIERFDEFRSALEAAADAGE
CEEEEECCCEEEEEECCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PISLASVALRAPLPKPSNIVCMAVNYMEDGTLAEPPAINAFHKAPTAVIGPGGTMVLPDI
CHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHCCCCEEECCCCEEEECCC
PARTFEGEAEMALVIGKRAHQVSAENWRDYVFGYVNFIDGSARGTLPEKNNYFQMKSRDT
CCCCCCCCCCEEEEECCHHHHCCHHHHHHHEEEEEEEECCCCCCCCCCCCCEEEECCCCC
FAPIGPWIVTADEIPDPQSLQVRLWVNGTLKQDFNTDDMAHKIPRCIEWLSHIQVLEPGD
CCCCCCEEEEECCCCCCCCEEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHCEEECCCC
VVATGTNHRGLNALQDGDSVELEIEGLGRLAINVRDDLKRTWPRDTRVELMAKGVKGPAV
EEEECCCCCCCCHHCCCCEEEEEEEECCEEEEEEHHHHHHHCCCCCHHHHHHCCCCCCEE
QLTGKHAPVSP
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]