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The map label for this gene is dppA [H]

Identifier: 222102659

GI number: 222102659

Start: 299936

End: 300754

Strand: Reverse

Name: dppA [H]

Synonym: Avi_7323

Alternate gene names: 222102659

Gene position: 300754-299936 (Counterclockwise)

Preceding gene: 222102660

Following gene: 222102658

Centisome position: 47.6

GC content: 58.24

Gene sequence:

>819_bases
ATGAAAATTCTCATCTCTGTCGATATCGAAGGGGTCGCTGGCGTCTATCACCCGGAACAAACCCGCGCGGGCAATGGCGA
ATATGAACGCGCCCGCCTGTTGATGACGGACGAAGCCAACGCCGCCATTGCTGGTGCCTTTGATGCCGGGGCAACGGAGG
TGTTTGTCAACGATTCCCACGGATCGTTTCGCAACATGCCGCCAGATCGGCTGGACCCGCGCGCCCGCGCCATTCAGGGC
AAACCCCGCTACCTCAGCATGATGTCTGGCGTTGAACTTGGTGTCGATGGCGTTTGCCTCATCGGCTATCATTCCCGTGG
GCAGGGCTTTGGCATTCTGGCCCACACCATCAACAGCTTTGCCTTTTCGCGGATATTCCTCAACGGACAGGAACTGGGCG
AAGCGGGCATTTATGGCGCTTTGGCGGGTGAATATGGCGTGCCGGTGATCATGGGCAGCGGCGATGATGTGTTCATTGCC
GAGAACAAAGACCTGTTTCCCAAAACCGTGTTTGTGGAGACCAAAAAGGCAAGCGGTGGCATCAGCGGCGTCAGCCTGTC
GCCATCGGAATCCTGTCTTGCCATTCGTGAGGGCGCGCGGGCTGCGGTGGAACAGGCGAGGCAAATGCCCAAATTTACCC
TGACTGGCCCCATTTCTGTGACCATCGAAACCCAATCCACCCGGCTGGCTGATCTGTTTTGCCAATGGCCAACCCTTGCC
CGCACCGGCGGCAATGAGGTGGCGTTCGAAGCGCCAAGCGTTGAACATGCCGTGCGGATGATCAACAGCCTATCCGCCAT
GTCCACCATGCTGCGCTAA

Upstream 100 bases:

>100_bases
ATCGACCGGAAATAACCCCTTCTGCAAGTTTTTGTTTGACGCATTTTCGAACGCAAAACCGCGATACACTTTTGCTCGAA
ATGCTCTTATGGAGTACCCC

Downstream 100 bases:

>100_bases
CGGCGGGCGATCTATTTTGAGCATTTCGAGGCATTTATGAGCAATACCCAACCAAGCCCCTTTGCGATTGCCATTCACGG
CGGCTGCGGCGTGATGAACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKILISVDIEGVAGVYHPEQTRAGNGEYERARLLMTDEANAAIAGAFDAGATEVFVNDSHGSFRNMPPDRLDPRARAIQG
KPRYLSMMSGVELGVDGVCLIGYHSRGQGFGILAHTINSFAFSRIFLNGQELGEAGIYGALAGEYGVPVIMGSGDDVFIA
ENKDLFPKTVFVETKKASGGISGVSLSPSESCLAIREGARAAVEQARQMPKFTLTGPISVTIETQSTRLADLFCQWPTLA
RTGGNEVAFEAPSVEHAVRMINSLSAMSTMLR

Sequences:

>Translated_272_residues
MKILISVDIEGVAGVYHPEQTRAGNGEYERARLLMTDEANAAIAGAFDAGATEVFVNDSHGSFRNMPPDRLDPRARAIQG
KPRYLSMMSGVELGVDGVCLIGYHSRGQGFGILAHTINSFAFSRIFLNGQELGEAGIYGALAGEYGVPVIMGSGDDVFIA
ENKDLFPKTVFVETKKASGGISGVSLSPSESCLAIREGARAAVEQARQMPKFTLTGPISVTIETQSTRLADLFCQWPTLA
RTGGNEVAFEAPSVEHAVRMINSLSAMSTMLR
>Mature_272_residues
MKILISVDIEGVAGVYHPEQTRAGNGEYERARLLMTDEANAAIAGAFDAGATEVFVNDSHGSFRNMPPDRLDPRARAIQG
KPRYLSMMSGVELGVDGVCLIGYHSRGQGFGILAHTINSFAFSRIFLNGQELGEAGIYGALAGEYGVPVIMGSGDDVFIA
ENKDLFPKTVFVETKKASGGISGVSLSPSESCLAIREGARAAVEQARQMPKFTLTGPISVTIETQSTRLADLFCQWPTLA
RTGGNEVAFEAPSVEHAVRMINSLSAMSTMLR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 29051; Mature: 29051

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILISVDIEGVAGVYHPEQTRAGNGEYERARLLMTDEANAAIAGAFDAGATEVFVNDSH
CEEEEEEECCCEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCEEEEEECCC
GSFRNMPPDRLDPRARAIQGKPRYLSMMSGVELGVDGVCLIGYHSRGQGFGILAHTINSF
CCCCCCCCCCCCCHHHHCCCCCHHHHHHCCCEECCCCEEEEEECCCCCCCCHHHHHHHHH
AFSRIFLNGQELGEAGIYGALAGEYGVPVIMGSGDDVFIAENKDLFPKTVFVETKKASGG
HEEHEEECCHHHCCCCCEEEECCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEECCCCC
ISGVSLSPSESCLAIREGARAAVEQARQMPKFTLTGPISVTIETQSTRLADLFCQWPTLA
CCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCEEEHHHHCCCCHH
RTGGNEVAFEAPSVEHAVRMINSLSAMSTMLR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILISVDIEGVAGVYHPEQTRAGNGEYERARLLMTDEANAAIAGAFDAGATEVFVNDSH
CEEEEEEECCCEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCEEEEEECCC
GSFRNMPPDRLDPRARAIQGKPRYLSMMSGVELGVDGVCLIGYHSRGQGFGILAHTINSF
CCCCCCCCCCCCCHHHHCCCCCHHHHHHCCCEECCCCEEEEEECCCCCCCCHHHHHHHHH
AFSRIFLNGQELGEAGIYGALAGEYGVPVIMGSGDDVFIAENKDLFPKTVFVETKKASGG
HEEHEEECCHHHCCCCCEEEECCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEECCCCC
ISGVSLSPSESCLAIREGARAAVEQARQMPKFTLTGPISVTIETQSTRLADLFCQWPTLA
CCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCEEEHHHHCCCCHH
RTGGNEVAFEAPSVEHAVRMINSLSAMSTMLR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]