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The map label for this gene is dppC [H]

Identifier: 222102660

GI number: 222102660

Start: 300840

End: 301742

Strand: Reverse

Name: dppC [H]

Synonym: Avi_7325

Alternate gene names: 222102660

Gene position: 301742-300840 (Counterclockwise)

Preceding gene: 222102661

Following gene: 222102659

Centisome position: 47.76

GC content: 56.15

Gene sequence:

>903_bases
ATGAGCAATACCACATCTGCCCCAATTGCCGCCGCTGCACAGACCAGCCGCGCTGTTCGCACCCCTTGGAGCGAATTTTG
GCGCAAATTCAAACGCCAGCCCGTGGCGCTTGGGGCCTTGGCCTTCATTGTGATTTTGATGGTTTTGGCCATCGCGGCAC
CCGTGATTGCGCCCTATGACGCTGAAAATTTCTTTGACTACGACATGATCAATGCCGGGCCTTCCTTGAGCCATTGGTTT
GGCGTTGATCCATTGGGCCGAGATATTTTCAGCCGTATTTTGATGGGCGCGCGGATTTCGCTGGCAACCGGCCTTTTGTC
CGTCACGCTCGGCGGCTTTATCGGCACCGTGTTTGGCTTGCTGGCTGGCTATTATGAAGGCTGGTGGGACCGGGTGGTGA
TGCGCATCTGCGATGTGCTGTTTGCCTTTCCGGGCATTTTGCTGGCTCTGGGCATTGTGGCCATTCTCGGCAGTTCCATG
GTCAATGTGGTGGCGGCCGTTGCAGTGTTTTCGGTTCCCGCCTTTGCCAGACTGGTGCGCAGCAGCACGCTGGTGCTGAA
AAACATGACCTATATTGAAGCCGTCAGAAGCGTTGGCGCATCCGACTTCATCATTCTGTTTCGCCATATTCTGCCGGGGG
CTTTTTCGTCGATTGTGGTCTATTTCACCATGCGACTTGGCACATCGATCATCACCGCCGCCAGCCTGTCCTTTCTCGGC
CTCGGTGCACAGCCACCCACGCCTGAGTGGGGTGCCATGCTGAATGACGCGCGCGCCGATATGGTCAATGCACCGCATGT
GGCGCTGTTTCCAAGCCTTGCGATTTTCGTCACTGTTCTGGCCTTCAACCTGCTAGGCGATGGCCTTCGCGATGCGATTG
ATCCGAAAATCGACCGGAAATAA

Upstream 100 bases:

>100_bases
CTCGTGCTGATGTTCTCGCTGGAATTCATCCTGATCAATCTTGTCGTGGATCTGCTCTACGGCGTCATCAATCCGACAAT
CCGTTATAAATGAGCCGGCC

Downstream 100 bases:

>100_bases
CCCCTTCTGCAAGTTTTTGTTTGACGCATTTTCGAACGCAAAACCGCGATACACTTTTGCTCGAAATGCTCTTATGGAGT
ACCCCATGAAAATTCTCATC

Product: ABC transporter membrane spanning protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSNTTSAPIAAAAQTSRAVRTPWSEFWRKFKRQPVALGALAFIVILMVLAIAAPVIAPYDAENFFDYDMINAGPSLSHWF
GVDPLGRDIFSRILMGARISLATGLLSVTLGGFIGTVFGLLAGYYEGWWDRVVMRICDVLFAFPGILLALGIVAILGSSM
VNVVAAVAVFSVPAFARLVRSSTLVLKNMTYIEAVRSVGASDFIILFRHILPGAFSSIVVYFTMRLGTSIITAASLSFLG
LGAQPPTPEWGAMLNDARADMVNAPHVALFPSLAIFVTVLAFNLLGDGLRDAIDPKIDRK

Sequences:

>Translated_300_residues
MSNTTSAPIAAAAQTSRAVRTPWSEFWRKFKRQPVALGALAFIVILMVLAIAAPVIAPYDAENFFDYDMINAGPSLSHWF
GVDPLGRDIFSRILMGARISLATGLLSVTLGGFIGTVFGLLAGYYEGWWDRVVMRICDVLFAFPGILLALGIVAILGSSM
VNVVAAVAVFSVPAFARLVRSSTLVLKNMTYIEAVRSVGASDFIILFRHILPGAFSSIVVYFTMRLGTSIITAASLSFLG
LGAQPPTPEWGAMLNDARADMVNAPHVALFPSLAIFVTVLAFNLLGDGLRDAIDPKIDRK
>Mature_299_residues
SNTTSAPIAAAAQTSRAVRTPWSEFWRKFKRQPVALGALAFIVILMVLAIAAPVIAPYDAENFFDYDMINAGPSLSHWFG
VDPLGRDIFSRILMGARISLATGLLSVTLGGFIGTVFGLLAGYYEGWWDRVVMRICDVLFAFPGILLALGIVAILGSSMV
NVVAAVAVFSVPAFARLVRSSTLVLKNMTYIEAVRSVGASDFIILFRHILPGAFSSIVVYFTMRLGTSIITAASLSFLGL
GAQPPTPEWGAMLNDARADMVNAPHVALFPSLAIFVTVLAFNLLGDGLRDAIDPKIDRK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=280, Percent_Identity=73.9285714285714, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1787760, Length=271, Percent_Identity=37.2693726937269, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=44.0140845070423, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=36.1702127659575, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=37.5, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=38.0952380952381, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788505, Length=246, Percent_Identity=31.3008130081301, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32261; Mature: 32130

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTTSAPIAAAAQTSRAVRTPWSEFWRKFKRQPVALGALAFIVILMVLAIAAPVIAPYD
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AENFFDYDMINAGPSLSHWFGVDPLGRDIFSRILMGARISLATGLLSVTLGGFIGTVFGL
CCCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGYYEGWWDRVVMRICDVLFAFPGILLALGIVAILGSSMVNVVAAVAVFSVPAFARLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTLVLKNMTYIEAVRSVGASDFIILFRHILPGAFSSIVVYFTMRLGTSIITAASLSFLG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGAQPPTPEWGAMLNDARADMVNAPHVALFPSLAIFVTVLAFNLLGDGLRDAIDPKIDRK
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNTTSAPIAAAAQTSRAVRTPWSEFWRKFKRQPVALGALAFIVILMVLAIAAPVIAPYD
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]