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The map label for this gene is yisQ [H]

Identifier: 222102653

GI number: 222102653

Start: 290930

End: 292306

Strand: Direct

Name: yisQ [H]

Synonym: Avi_7312

Alternate gene names: 222102653

Gene position: 290930-292306 (Clockwise)

Preceding gene: 222102652

Following gene: 222102654

Centisome position: 46.05

GC content: 59.84

Gene sequence:

>1377_bases
ATGCAGACAGTTGAAACCCTTGGCGATGCGGCCCCGCCGCGCCGCCCGCCATCGGCGCGAACGACAAAGTCGCTTTTCCG
GCTTAGCCTGCCGATGTTCGTGCATTCGCTGCTGACCTTTCTGGTCATGCTGTCGGAAATGCTGATCATGAGCGCTTATT
CCGCCAATGCGGCAGCAGCCGTGGCGATTGTGCGGCAGGTGCTCCAAGTCGTCTTCGAGATTTCGAGCATGGTCGGGATC
GGCGCTGTCATCCTGATATCGCACAGTCTCGGGCGTGGTGACGAGGAGGGTGCGCGGCAGATCGCAACGCTTGCGGTCTT
CACCAATACGCTCCTTGGCCTTTTGGTAGGCGGTCTGCTGTTTCTGGGTGGACCGGTGGCCTTGCGGATTCTCGATGTCC
CGGCATCAATCGTTCACGATGCAAGCCTTTATCTTGTCCTCGCTGCCGCCGCCATGGTCTTCAATGCGCTTGCCACGGCT
GCGATTGCCTGCCTGAGGGCTTTCGGCAGCAGCCGGGTGATCGTGATGACCGGCTTGTTTCTGTCGGTGATTTACATTGG
GGCGACCTATGTTCTTGTGCTTGGTGCCGGACCAATCCCCCCGCTTGGGGTGACAGGTGCGGCCTATGCAACACTCGGCT
CAAGGATTGCAATGGCGCTGATGTTCGGCCTTGCCGTCTATTGCGCCCTTGGTCTTCGTTTCGCCTCTGGGCCGATCAGG
GCGCGGCTTTCGCTCGTGCGGCGCATGCTTGTCCTCGCCTTTCCGAGTGTTTCGGACTATATCGGCTACGGTTTTTACCA
GCTTGTGCTGCTCGGCTTTGTGGCGGGCTTCGGCGTTTCAAGTGTCTTGAGCCGTACCTATGTCATGCTGGCCATGACGT
TCCTCATCCTTGTCGTTATGGCTGTGAGCCAAGGAAACGAGGTGCTCGTCGGCTATCGCTGGGGCGAAGGTCGGCGGCAG
GACGCCTATCGTCAGGCGTTGCGCTCCAGCTTTGCGGCGACCTTGGTCACGACGACAATCGCGCTGCTGTTCTGGCTCAT
GTCCGATCAATATCTCGGATTGTTCGGGCAGGGCGGTGAGGTTCTGGCGCTTTCCACCTACCTGCTGCTGCTGACGATCT
TCATCCAGCCCGGCTTCGCCTTCAATACAGTGTTGCTGCATTCGCTCAGGGCTGTCGGCGATGTCAGGATTCCGGTCCTC
GTCAGTATCGGCTTGACCTGGGGGCTCGGCCTGCCGCTGGCCTGGCTGTTTTGCGTGCAGGCGGACTATGGGGTGGAAGG
TGTCTGGTACGCGCTGATCATCGAAGAGACACTCAAGGCCGGTTTCATGCTTTCGCGCTGGCACGGGCGGGGATGGATGG
GCAATGCCATTGCCTGA

Upstream 100 bases:

>100_bases
CCAGTGGTCTGGAGGTGATCGAACCCTCTTGCGCCAGACGGGCCGCGATCGCCTTGCAGGTCGTCGTGGCCTGCGGGCCG
AACGCACAGGTGCCTGACGC

Downstream 100 bases:

>100_bases
TATTGTTTTGCACAATGAAGCCCATGGTCACCATCAGCCAAATATGCGACTATGGCTGAACGAGTAACTCCCTTGATAGT
GTCATCCATGCGCCTGAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQTVETLGDAAPPRRPPSARTTKSLFRLSLPMFVHSLLTFLVMLSEMLIMSAYSANAAAAVAIVRQVLQVVFEISSMVGI
GAVILISHSLGRGDEEGARQIATLAVFTNTLLGLLVGGLLFLGGPVALRILDVPASIVHDASLYLVLAAAAMVFNALATA
AIACLRAFGSSRVIVMTGLFLSVIYIGATYVLVLGAGPIPPLGVTGAAYATLGSRIAMALMFGLAVYCALGLRFASGPIR
ARLSLVRRMLVLAFPSVSDYIGYGFYQLVLLGFVAGFGVSSVLSRTYVMLAMTFLILVVMAVSQGNEVLVGYRWGEGRRQ
DAYRQALRSSFAATLVTTTIALLFWLMSDQYLGLFGQGGEVLALSTYLLLLTIFIQPGFAFNTVLLHSLRAVGDVRIPVL
VSIGLTWGLGLPLAWLFCVQADYGVEGVWYALIIEETLKAGFMLSRWHGRGWMGNAIA

Sequences:

>Translated_458_residues
MQTVETLGDAAPPRRPPSARTTKSLFRLSLPMFVHSLLTFLVMLSEMLIMSAYSANAAAAVAIVRQVLQVVFEISSMVGI
GAVILISHSLGRGDEEGARQIATLAVFTNTLLGLLVGGLLFLGGPVALRILDVPASIVHDASLYLVLAAAAMVFNALATA
AIACLRAFGSSRVIVMTGLFLSVIYIGATYVLVLGAGPIPPLGVTGAAYATLGSRIAMALMFGLAVYCALGLRFASGPIR
ARLSLVRRMLVLAFPSVSDYIGYGFYQLVLLGFVAGFGVSSVLSRTYVMLAMTFLILVVMAVSQGNEVLVGYRWGEGRRQ
DAYRQALRSSFAATLVTTTIALLFWLMSDQYLGLFGQGGEVLALSTYLLLLTIFIQPGFAFNTVLLHSLRAVGDVRIPVL
VSIGLTWGLGLPLAWLFCVQADYGVEGVWYALIIEETLKAGFMLSRWHGRGWMGNAIA
>Mature_458_residues
MQTVETLGDAAPPRRPPSARTTKSLFRLSLPMFVHSLLTFLVMLSEMLIMSAYSANAAAAVAIVRQVLQVVFEISSMVGI
GAVILISHSLGRGDEEGARQIATLAVFTNTLLGLLVGGLLFLGGPVALRILDVPASIVHDASLYLVLAAAAMVFNALATA
AIACLRAFGSSRVIVMTGLFLSVIYIGATYVLVLGAGPIPPLGVTGAAYATLGSRIAMALMFGLAVYCALGLRFASGPIR
ARLSLVRRMLVLAFPSVSDYIGYGFYQLVLLGFVAGFGVSSVLSRTYVMLAMTFLILVVMAVSQGNEVLVGYRWGEGRRQ
DAYRQALRSSFAATLVTTTIALLFWLMSDQYLGLFGQGGEVLALSTYLLLLTIFIQPGFAFNTVLLHSLRAVGDVRIPVL
VSIGLTWGLGLPLAWLFCVQADYGVEGVWYALIIEETLKAGFMLSRWHGRGWMGNAIA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=425, Percent_Identity=21.8823529411765, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48936; Mature: 48936

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVETLGDAAPPRRPPSARTTKSLFRLSLPMFVHSLLTFLVMLSEMLIMSAYSANAAAA
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VAIVRQVLQVVFEISSMVGIGAVILISHSLGRGDEEGARQIATLAVFTNTLLGLLVGGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGGPVALRILDVPASIVHDASLYLVLAAAAMVFNALATAAIACLRAFGSSRVIVMTGLF
HHCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LSVIYIGATYVLVLGAGPIPPLGVTGAAYATLGSRIAMALMFGLAVYCALGLRFASGPIR
HHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ARLSLVRRMLVLAFPSVSDYIGYGFYQLVLLGFVAGFGVSSVLSRTYVMLAMTFLILVVM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AVSQGNEVLVGYRWGEGRRQDAYRQALRSSFAATLVTTTIALLFWLMSDQYLGLFGQGGE
HHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCC
VLALSTYLLLLTIFIQPGFAFNTVLLHSLRAVGDVRIPVLVSIGLTWGLGLPLAWLFCVQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADYGVEGVWYALIIEETLKAGFMLSRWHGRGWMGNAIA
CCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQTVETLGDAAPPRRPPSARTTKSLFRLSLPMFVHSLLTFLVMLSEMLIMSAYSANAAAA
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VAIVRQVLQVVFEISSMVGIGAVILISHSLGRGDEEGARQIATLAVFTNTLLGLLVGGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGGPVALRILDVPASIVHDASLYLVLAAAAMVFNALATAAIACLRAFGSSRVIVMTGLF
HHCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LSVIYIGATYVLVLGAGPIPPLGVTGAAYATLGSRIAMALMFGLAVYCALGLRFASGPIR
HHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ARLSLVRRMLVLAFPSVSDYIGYGFYQLVLLGFVAGFGVSSVLSRTYVMLAMTFLILVVM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AVSQGNEVLVGYRWGEGRRQDAYRQALRSSFAATLVTTTIALLFWLMSDQYLGLFGQGGE
HHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCC
VLALSTYLLLLTIFIQPGFAFNTVLLHSLRAVGDVRIPVLVSIGLTWGLGLPLAWLFCVQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADYGVEGVWYALIIEETLKAGFMLSRWHGRGWMGNAIA
CCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]