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The map label for this gene is tycC [H]

Identifier: 222102652

GI number: 222102652

Start: 284375

End: 290926

Strand: Direct

Name: tycC [H]

Synonym: Avi_7311

Alternate gene names: 222102652

Gene position: 284375-290926 (Clockwise)

Preceding gene: 222102651

Following gene: 222102653

Centisome position: 45.01

GC content: 61.77

Gene sequence:

>6552_bases
CTGCCCGTGAACTCTGCCGATCCGATTCTGGCGCTGCGCGCCCGCGTTGCGGCGCTCAGTCCTGCTGAGCGCGAGGCTTT
CCGCCGCCAGCTCGAAGCCCGTGGGATCGCCTGGGAACGGGTGGCCCCGGAAGAGACGCCACAAGAGACGTCAAGGGTGT
CAACGCGCCCCGCCCGCTTGCCGCTGACACCCGGCCAGAAGCATTTCTGGCTCCAGCAGAGCCTCTATCCCGAGAGTTCT
GCTTATCACGTCGCCTATCGCTGGCGGTTTGAGGGGCCGCTTGATCGCGCAGCCCTTGAGCGCAGCCTTGCAACGATTGT
CTCCCGGCATGCGCCGCTCAGAACCGCCTTTCCCGTCGAGGCGGGCGAGCCGTGGCAGGAGGTTCATCCAGACCATGCTT
TTGCTCTGGGCTTTACCGATCTGGAAGCGACAGGCGAGGATGGTGAGGCGCTGGCGCTGGCTGTTGCGACTGAGCCTTTC
GATCTCTCAAAGGCACCGCTGATCAGGGCACATCTCTTCCGGCAGCATGAGAGCGAGCACCTGCTGGCGATCACCCTCCA
TCACATCGTTGCGGATGGCTGGTCACGCGGTGTGCTGATGCGCGAGCTGACGGCCTGCTACCGCGCCTATCGTATGGGTG
CTGCGCCCGCGCTTTCGCACATCACGCGTGATTTTGGGGATCTGGTTCTCGATCAACACGCATGGCTTCAGCGCCGGGAT
TGCGGACGAGACCGCGACTACTGGAAACAAACCCTCGCCGATCTCAAGCCGCTGGAATTGCCAAGCGACCGATCCCGCAG
CAGCAGCGTTGACATGACGGCGGCCACCGTGACACGGGTTATTCCCGTCTCGGTGTCGTCGCAGGTCGCATCGCTCGCCA
GCCAGCTTGGAACCACGCCTTTTGTGGTGATGGCTGCGGCCTTTTCGCTGCTGCTTCATCGCTACAGTGGCGAGCGTGAC
CTGTCGGTCTGCGTGCCCGTTGCCGGACGGGACAATCCGGATGCCGCAGGGCTGATTGGGCTGTTTACCAACACATTGGT
GCTGCGCGCGCAACTCGACCCGCGCATGACGTTTTCGCAGTGGGTCGGGGCGGTTCAGGAGCGCTTCTCGGACGCGCTCG
ACCATCAGGCATTTCCCTTTCCGCTGATTGCTGAGGCACTTGGCATGAGCCGCGACCAACGGCAGAGCCCGCTTTCGCAG
GTTATGTTCCAGTTGCAGTCGCAAGACTACCGCGCACAGAATGCCGAGCAGATCGATTTCGGCATCGATGGTCTCATTGT
TCGCCAACAGCCAGCACGGCTGAGTGAAACAAAGGTCGATCTCAGCTGGTATGTGATGGAGCGGGAATCCGGCTATCTGC
TGAACATCGAATATCGCGTGGCGATCTTTGATGCCTGGCGGATCGAGCGCATGGCCGCCCATTTCGAGGTTTTGCTCGGC
TCCATCCTGCAATCTCCCAATGCTCTGCTGCCAAGGCTTGCCTATCTATCAAAGGAAGAGCATGCAACTGTGGTTGCACT
TGGAACGCCAACCGCGCGGCCCGTGCCTGACATCACCATGCACGATGCCATTGCGCACGTTGCCCGGCACCAACCCGATG
CCATTGCACTGGAAAGCAAGGGCCAAAGTTGGACCTATGGCGAATTACAGAAAGATGTGGACGCACTTACTGACACGCTC
GTCGGCCTTTCGGTTCACCCCGGCGATAGGGTTGCCGTTTCGCTGCCGGGCAGGGGGCAATCCGTCATTGCTTTCCTCGC
CATTCTGAAAGCGGGTGCCGTCTATGTTCCGCTCGATCCCGATCATCCAGCGGACCGGGTTGCCTATATGCTTGAGGATT
CCGGTGTCAGTCTCGTATTGACGGACAGGGCCGATCTCTATCCGGCCCAGCGCTCCCTTGATCCGACCCGCCCGCTGCCG
GTGAGCGAGACCCCTGCCGCGCTGCCGCCCTCTGATCCCGCGCGCATTGCCTATCTTCTCTACACCAGCGGCAGTACGGG
CCGACCGAACGGCGTGCCGATTGCCCATGCAAGCCTGCTCAATCACCTGCGCTCTATGGCCGTCTCGCCGGGGCTTGCGC
CCGGTGATCGGCTTTTGGCAATCACCACGCCCACCTTCGACATTTCCATTCTGGAAATGCTCCTGCCGCTCAGCGTCGGC
GCGACCACCGTGCTTTACGGCCAAGACCTGCTGCTTGCGCCACAGCGGCTTGCCGATGTGCTTGTGACCGATCGCATCTC
ACATTTGCAGGCAACACCCGCCTATTGGCGCATGTTGATCGACAGCGGCTGGGAGGGATTGCCGCATCTGATAGCCCTTT
GCGGCGGCGAGGCACTGGATGCACCGCTTGCCCGCAAGCTGATCGACCGTACGAAAGAGCTATGGAACGTCTATGGGCCG
ACAGAGGCGACAATCTGGGCAAGCGCGCTGAAGGTCACCCACGCCCACGCGGAAAGCGGCAAGGTTCCCGTTGGTGGCCT
GCTCGACAATACCCACCTTCACGTTCTCGACGCCTATATGCAGCCCTTGCCGCGCGGCATTGGCGGCGAACTCTATATCG
GCGGGCCGTGCCTCAGCCCCGGTTACTGGAACCGCCCGGCTCTTACTGCCGCCCGTTTCGTGCCGAACCCGTTCTATGAT
GAAAACAGCCCTGCGCTTAGGCTCTATCGCACCGGCGATGCGGTTGTTCGTCTGGCAAATAGCGAGATCGAATTTATCGG
CCGCACGGATTTTCAGGTCAAGCTGCGCGGCTACCGCATCGAGATCGGTGAGATCGAGGACAAGCTGCTGCGCGAAAGCG
TTGTTGAGCAGGCCATCGTCACGCTCGACGCCGAAAACGAACGGCTGATTGCCTATGTGCTCGTTCGCGATTGGCCGACA
ACGAACGATGGCGAGATTGAGCGCAAGCTGCGCCAGTCGCTGTCCGCGCAATTGCCGCGCTACATGGTTCCGACCGCCTT
TGTGATTCTGGAGGAGTTTCCGCTCAATCCGAATGGCAAGGTGGATCGCAAGCAGCTTCCGATCCCCCAGCTTTCCACAA
CGCGCGCGGAGCCAATTCCAGCCCGCAATGCCATCGAGGCGACGCTACTGGAAATATGGAAGGCCGTGCTGCGGCGGGAA
GATATCGGCATCGAGGATAATTTCTTCGATCTCGGTGGTGACTCCATTATCGGGGTTCAGATCGTTGCGAAGGCGCAAGC
CAAGGGGCTGAAGCTCGAACCGACCCAGATTTTCGAGTTGCAGACAATCGCGGCACAGGCAATCGCAGCCGTTGCCGAAA
GCGCGGTCCATACGATTGAGGTTCAGGCAATTGAGGTTGCCGAAAGCGGACCCAGCTTCGAGATGACGCCAGTGCAGGCG
GGCATGCTGTTCCACAGTCTGATGGCCCCAGCCTCAGGGACCTATATCGAGCAATGCTGGTGCGTGCTGGAAGGCACGTT
GGATGCCGATGCCTTCAAATCGGCGTGGGGGAGGGTGATCGCCCGCCACGAGGTCTTGCGCGGTGCCTGCCGCTGGACGG
ATGTCGAGCGGCCCATCATGGTCATTGCCGAGGATGTTGTGCCGGAATGGCGCGAAGCGGACTGGTCGGGCGAAGACGCG
GCAGGGCAGGAGACAGCCTTTGCGGCATGGCTGGAGGCGGATCGCCGTCGTGGCTTTACGCTGGATGCTGCACCCCTTTT
GCGGTTTGCGCTGATCCGGCTCGGTCCCGGCCGCCATCGCTTCGTCTGGAGTTTCCACCACCTGTTGATGGACGGCTGGT
GCGGCTCGCTCTTGGTCGGTGAAATGTTGAAGGCTTATGCAGGCGAAAGCCTGCCAGCGCCTCCCCCGTCTTATCGCCAA
TACGTCGCGTGGCGCGACCGGCAGGATATCACGGCTGCACAAGCCTATTGGTCGCACGCTCTTGCCGATCTGCCGCAAGG
CGGATTTTTGGGAGAGACAAAAATTGGCGAGGCGGCACAGGAGGCCATTATCGAGATCCGGCGCAGCCTTGACGCCAGTC
TCGCAACGCGGCTTGCCGCCATGGCGCGGCGGGAGCGGCTGACGCTGGCGACCGTGCTACAGGGGGCCTGGGCGCTGCTT
CTATCGCGCTATGGGGCCGAGGATGATGTGATCTTCGGAACGGTTTTGTCGGGCCGCCCGCCTGACCTGCCAGATGCAGA
CCGAATGATTGGCCTGTTCCTCAACACGGTGCCGTTTCGTGCCCGGACACGACCGGAGGAGAGGGTGGCCGAATGGCTTC
AAGGCCTCCAGTCTGCGCATCGCCAGCGGGAAAAGCACGGGCATGCAGCGCTTGCCGATATCCAGCGCTGGGCTGGCAAG
ACCGCCGATCAACCGCTTTTCGACACATTGCTGATCATCGAGAACCTGCCGCTTTCGATGCAGGCGGCCTTTGCGGAAGG
AACGCACACGCTCACCCTCAGCGATCCCGGCAGCTATGAGCGCACGCATTACCCGTTGTCGCTCCGGATCTTTCCCGGTG
CCGAGATAGAGATTGCGCTTGCCGCAGACCCGTCACGTCTGTCGTCCACCAAAGCTGATCGTCTGCTGCGGCATTACGAG
ACTTTGCTCTCATCCATCGCCGATGATCCACGGGCATGCCTTGGCACAATTGAGATGCTTAAGCCCGATGAGCGAGACAT
CCTGCTCCAGACGGGCCGAGGTCCGCAGACGCAGCCATGTGCTGCCGTGCATGACCAGATCATCGCACGGGCGAAAGAAG
AACCGGGCAAAGCCGCCGTCGTTCAGGTGGGTGAGGGCCGCGATAGCACCATGTCCTATGGCGATCTCGCAGGTTATGCG
GAGGCTCTTGCCCTTCGTCTTTACCAGCAAGGCATTGGCCGGGGCGCGGTCGTTGCGGTCTATCTACGGCGTGGAAGCGC
ATTGCTGCCCTCACTGCTGGCCGTCATGCGGTCGGGTGCTGCCTATCTGCCAATTGATCCCGACTATCCGGCAGAGCGCA
TTGCCTACATGCTGGCCGATTCTGGTGCAGCACTGGTCCTGACGGATCTTGGGGACAGTGAGCGGGCGGTTATACCGCAA
GATGTTCCGGTGCTGGACCCGACTGAGGCATTCGGTTGTGCGCAGGCATCCTTCGAACCTGCTGCGGTGCAGGCCGATGA
TCTCGCCTACATTCTTTATACCAGCGGCAGCACCGGCCAGCCCAAGGGCGTGGCAATCACCCATGGTGCGCTTGCCAATT
TCATCGAGTCCATGGCCGACAGGCCGGGGATTGGCGCGGACGACCGCCTGCTGGCGCTGACCACGATTGGCTTCGACATT
GCGGGGCTGGAATTGTTCGCGCCTCTTTCGCAAGGCGCAACAGTGCTGCTTGCGGACAGCGCCATTGCCCGCGACGGTCG
GCGTCTTGCCGCGCTCGTGGATCGTGTGCAGCCGAGTGTCATGCAGGCAACGCCCGCCGGGTGGCGCATGCTGATCGAGG
CGGGGTGGCGCGGCTCTCAGGAGCTTCGTATGCTGTGCGGCGGCGAGGCGCTGGACAGCCTTCTTGCGGCGGAGTTGCTG
GATCGGGGCGATTGCCTGTGGAATCTTTACGGTCCAACCGAGACAACCATCTGGTCTGCGGCCACTGAGGTGCGGCGTGA
AGACCTCAATGGTCATAGCGTCACGGTTGCAGGCCCCATTCAGAATACCCAACTCTATGTTCTCGACCGGCGCGGGGAAC
CCGTACCACCGGGCACGCCGGGAGAATTGCACATCGGCGGTGCGGGATTGAGCCCGGGCTACTGGGGCAAACCCGGCCTG
ACGGCAGACAGGTTCATCCCCAACCCTTTCCGGCGTGGTCCGCAGGACGGCTACCATCTTTACCGCACTGGCGACCTCGT
GCGCTTGGCGGAGAATGGCGCGCTCGATTTTCTCGGACGGATCGACAATCAGGTGAAGCTGCGCGGCTACCGAATCGAAC
TCGGGGAGGTCGAGGCACGGCTTGCGGCCCATCCTCGCGTTGCTGAAGCGGCAGTGCTTGTCGAGGATGGCGGCGCTGGC
AAACAGCTCATCGCCTATCTGCGTTGGCGAGAGCCATTTGTCGGCGATGCAAGCGCGGAGCTTGGACCGCATGTGGCAGG
TAGCCTGCCGCTCTACATGCTGCCATCGGCCTATGTCGCGCTTGATGCCTTCCCGCTGACGCCAAACGGCAAGGTTGATC
GTCGCGCACTTCCGGCCTGCCGGCCAAAACCGGCACAGCGGCAAACGCACCTGCCGATCTCTGGCGAGCCCGCTGCAACG
CTTGCCGCCATCTGGCGAGAGGCGCTTAAAATCGACCACGTCAATCCGGGTGACAATTTCTTTGAATGCGGCGGCCATTC
GCTGCTTGTTGTCTCTTTGCAGGGTGTGATCGGCAAGCGTTTTGGCGTATCGATTGATATTACGGCCTTTTTCCAGTTTC
CGACACTGGAAACTCTGGCCGCCCATATCGCGCAGCTCCAAGCCGGTCGTGAAGGCCAGTGGTCTGGAGGTGATCGAACC
CTCTTGCGCCAGACGGGCCGCGATCGCCTTGCAGGTCGTCGTGGCCTGCGGGCCGAACGCACAGGTGCCTGA

Upstream 100 bases:

>100_bases
TGCAGGATTACGATCTTGTCATGGGCGGTCTGCCGCATCTCGCGCGGCTTGCGCGCCAGCATGCACCGCAGCCGACAATC
GCGCAAGTCGTATAGGGAGA

Downstream 100 bases:

>100_bases
CGCATGCAGACAGTTGAAACCCTTGGCGATGCGGCCCCGCCGCGCCGCCCGCCATCGGCGCGAACGACAAAGTCGCTTTT
CCGGCTTAGCCTGCCGATGT

Product: peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2183; Mature: 2182

Protein sequence:

>2183_residues
MPVNSADPILALRARVAALSPAEREAFRRQLEARGIAWERVAPEETPQETSRVSTRPARLPLTPGQKHFWLQQSLYPESS
AYHVAYRWRFEGPLDRAALERSLATIVSRHAPLRTAFPVEAGEPWQEVHPDHAFALGFTDLEATGEDGEALALAVATEPF
DLSKAPLIRAHLFRQHESEHLLAITLHHIVADGWSRGVLMRELTACYRAYRMGAAPALSHITRDFGDLVLDQHAWLQRRD
CGRDRDYWKQTLADLKPLELPSDRSRSSSVDMTAATVTRVIPVSVSSQVASLASQLGTTPFVVMAAAFSLLLHRYSGERD
LSVCVPVAGRDNPDAAGLIGLFTNTLVLRAQLDPRMTFSQWVGAVQERFSDALDHQAFPFPLIAEALGMSRDQRQSPLSQ
VMFQLQSQDYRAQNAEQIDFGIDGLIVRQQPARLSETKVDLSWYVMERESGYLLNIEYRVAIFDAWRIERMAAHFEVLLG
SILQSPNALLPRLAYLSKEEHATVVALGTPTARPVPDITMHDAIAHVARHQPDAIALESKGQSWTYGELQKDVDALTDTL
VGLSVHPGDRVAVSLPGRGQSVIAFLAILKAGAVYVPLDPDHPADRVAYMLEDSGVSLVLTDRADLYPAQRSLDPTRPLP
VSETPAALPPSDPARIAYLLYTSGSTGRPNGVPIAHASLLNHLRSMAVSPGLAPGDRLLAITTPTFDISILEMLLPLSVG
ATTVLYGQDLLLAPQRLADVLVTDRISHLQATPAYWRMLIDSGWEGLPHLIALCGGEALDAPLARKLIDRTKELWNVYGP
TEATIWASALKVTHAHAESGKVPVGGLLDNTHLHVLDAYMQPLPRGIGGELYIGGPCLSPGYWNRPALTAARFVPNPFYD
ENSPALRLYRTGDAVVRLANSEIEFIGRTDFQVKLRGYRIEIGEIEDKLLRESVVEQAIVTLDAENERLIAYVLVRDWPT
TNDGEIERKLRQSLSAQLPRYMVPTAFVILEEFPLNPNGKVDRKQLPIPQLSTTRAEPIPARNAIEATLLEIWKAVLRRE
DIGIEDNFFDLGGDSIIGVQIVAKAQAKGLKLEPTQIFELQTIAAQAIAAVAESAVHTIEVQAIEVAESGPSFEMTPVQA
GMLFHSLMAPASGTYIEQCWCVLEGTLDADAFKSAWGRVIARHEVLRGACRWTDVERPIMVIAEDVVPEWREADWSGEDA
AGQETAFAAWLEADRRRGFTLDAAPLLRFALIRLGPGRHRFVWSFHHLLMDGWCGSLLVGEMLKAYAGESLPAPPPSYRQ
YVAWRDRQDITAAQAYWSHALADLPQGGFLGETKIGEAAQEAIIEIRRSLDASLATRLAAMARRERLTLATVLQGAWALL
LSRYGAEDDVIFGTVLSGRPPDLPDADRMIGLFLNTVPFRARTRPEERVAEWLQGLQSAHRQREKHGHAALADIQRWAGK
TADQPLFDTLLIIENLPLSMQAAFAEGTHTLTLSDPGSYERTHYPLSLRIFPGAEIEIALAADPSRLSSTKADRLLRHYE
TLLSSIADDPRACLGTIEMLKPDERDILLQTGRGPQTQPCAAVHDQIIARAKEEPGKAAVVQVGEGRDSTMSYGDLAGYA
EALALRLYQQGIGRGAVVAVYLRRGSALLPSLLAVMRSGAAYLPIDPDYPAERIAYMLADSGAALVLTDLGDSERAVIPQ
DVPVLDPTEAFGCAQASFEPAAVQADDLAYILYTSGSTGQPKGVAITHGALANFIESMADRPGIGADDRLLALTTIGFDI
AGLELFAPLSQGATVLLADSAIARDGRRLAALVDRVQPSVMQATPAGWRMLIEAGWRGSQELRMLCGGEALDSLLAAELL
DRGDCLWNLYGPTETTIWSAATEVRREDLNGHSVTVAGPIQNTQLYVLDRRGEPVPPGTPGELHIGGAGLSPGYWGKPGL
TADRFIPNPFRRGPQDGYHLYRTGDLVRLAENGALDFLGRIDNQVKLRGYRIELGEVEARLAAHPRVAEAAVLVEDGGAG
KQLIAYLRWREPFVGDASAELGPHVAGSLPLYMLPSAYVALDAFPLTPNGKVDRRALPACRPKPAQRQTHLPISGEPAAT
LAAIWREALKIDHVNPGDNFFECGGHSLLVVSLQGVIGKRFGVSIDITAFFQFPTLETLAAHIAQLQAGREGQWSGGDRT
LLRQTGRDRLAGRRGLRAERTGA

Sequences:

>Translated_2183_residues
MPVNSADPILALRARVAALSPAEREAFRRQLEARGIAWERVAPEETPQETSRVSTRPARLPLTPGQKHFWLQQSLYPESS
AYHVAYRWRFEGPLDRAALERSLATIVSRHAPLRTAFPVEAGEPWQEVHPDHAFALGFTDLEATGEDGEALALAVATEPF
DLSKAPLIRAHLFRQHESEHLLAITLHHIVADGWSRGVLMRELTACYRAYRMGAAPALSHITRDFGDLVLDQHAWLQRRD
CGRDRDYWKQTLADLKPLELPSDRSRSSSVDMTAATVTRVIPVSVSSQVASLASQLGTTPFVVMAAAFSLLLHRYSGERD
LSVCVPVAGRDNPDAAGLIGLFTNTLVLRAQLDPRMTFSQWVGAVQERFSDALDHQAFPFPLIAEALGMSRDQRQSPLSQ
VMFQLQSQDYRAQNAEQIDFGIDGLIVRQQPARLSETKVDLSWYVMERESGYLLNIEYRVAIFDAWRIERMAAHFEVLLG
SILQSPNALLPRLAYLSKEEHATVVALGTPTARPVPDITMHDAIAHVARHQPDAIALESKGQSWTYGELQKDVDALTDTL
VGLSVHPGDRVAVSLPGRGQSVIAFLAILKAGAVYVPLDPDHPADRVAYMLEDSGVSLVLTDRADLYPAQRSLDPTRPLP
VSETPAALPPSDPARIAYLLYTSGSTGRPNGVPIAHASLLNHLRSMAVSPGLAPGDRLLAITTPTFDISILEMLLPLSVG
ATTVLYGQDLLLAPQRLADVLVTDRISHLQATPAYWRMLIDSGWEGLPHLIALCGGEALDAPLARKLIDRTKELWNVYGP
TEATIWASALKVTHAHAESGKVPVGGLLDNTHLHVLDAYMQPLPRGIGGELYIGGPCLSPGYWNRPALTAARFVPNPFYD
ENSPALRLYRTGDAVVRLANSEIEFIGRTDFQVKLRGYRIEIGEIEDKLLRESVVEQAIVTLDAENERLIAYVLVRDWPT
TNDGEIERKLRQSLSAQLPRYMVPTAFVILEEFPLNPNGKVDRKQLPIPQLSTTRAEPIPARNAIEATLLEIWKAVLRRE
DIGIEDNFFDLGGDSIIGVQIVAKAQAKGLKLEPTQIFELQTIAAQAIAAVAESAVHTIEVQAIEVAESGPSFEMTPVQA
GMLFHSLMAPASGTYIEQCWCVLEGTLDADAFKSAWGRVIARHEVLRGACRWTDVERPIMVIAEDVVPEWREADWSGEDA
AGQETAFAAWLEADRRRGFTLDAAPLLRFALIRLGPGRHRFVWSFHHLLMDGWCGSLLVGEMLKAYAGESLPAPPPSYRQ
YVAWRDRQDITAAQAYWSHALADLPQGGFLGETKIGEAAQEAIIEIRRSLDASLATRLAAMARRERLTLATVLQGAWALL
LSRYGAEDDVIFGTVLSGRPPDLPDADRMIGLFLNTVPFRARTRPEERVAEWLQGLQSAHRQREKHGHAALADIQRWAGK
TADQPLFDTLLIIENLPLSMQAAFAEGTHTLTLSDPGSYERTHYPLSLRIFPGAEIEIALAADPSRLSSTKADRLLRHYE
TLLSSIADDPRACLGTIEMLKPDERDILLQTGRGPQTQPCAAVHDQIIARAKEEPGKAAVVQVGEGRDSTMSYGDLAGYA
EALALRLYQQGIGRGAVVAVYLRRGSALLPSLLAVMRSGAAYLPIDPDYPAERIAYMLADSGAALVLTDLGDSERAVIPQ
DVPVLDPTEAFGCAQASFEPAAVQADDLAYILYTSGSTGQPKGVAITHGALANFIESMADRPGIGADDRLLALTTIGFDI
AGLELFAPLSQGATVLLADSAIARDGRRLAALVDRVQPSVMQATPAGWRMLIEAGWRGSQELRMLCGGEALDSLLAAELL
DRGDCLWNLYGPTETTIWSAATEVRREDLNGHSVTVAGPIQNTQLYVLDRRGEPVPPGTPGELHIGGAGLSPGYWGKPGL
TADRFIPNPFRRGPQDGYHLYRTGDLVRLAENGALDFLGRIDNQVKLRGYRIELGEVEARLAAHPRVAEAAVLVEDGGAG
KQLIAYLRWREPFVGDASAELGPHVAGSLPLYMLPSAYVALDAFPLTPNGKVDRRALPACRPKPAQRQTHLPISGEPAAT
LAAIWREALKIDHVNPGDNFFECGGHSLLVVSLQGVIGKRFGVSIDITAFFQFPTLETLAAHIAQLQAGREGQWSGGDRT
LLRQTGRDRLAGRRGLRAERTGA
>Mature_2182_residues
PVNSADPILALRARVAALSPAEREAFRRQLEARGIAWERVAPEETPQETSRVSTRPARLPLTPGQKHFWLQQSLYPESSA
YHVAYRWRFEGPLDRAALERSLATIVSRHAPLRTAFPVEAGEPWQEVHPDHAFALGFTDLEATGEDGEALALAVATEPFD
LSKAPLIRAHLFRQHESEHLLAITLHHIVADGWSRGVLMRELTACYRAYRMGAAPALSHITRDFGDLVLDQHAWLQRRDC
GRDRDYWKQTLADLKPLELPSDRSRSSSVDMTAATVTRVIPVSVSSQVASLASQLGTTPFVVMAAAFSLLLHRYSGERDL
SVCVPVAGRDNPDAAGLIGLFTNTLVLRAQLDPRMTFSQWVGAVQERFSDALDHQAFPFPLIAEALGMSRDQRQSPLSQV
MFQLQSQDYRAQNAEQIDFGIDGLIVRQQPARLSETKVDLSWYVMERESGYLLNIEYRVAIFDAWRIERMAAHFEVLLGS
ILQSPNALLPRLAYLSKEEHATVVALGTPTARPVPDITMHDAIAHVARHQPDAIALESKGQSWTYGELQKDVDALTDTLV
GLSVHPGDRVAVSLPGRGQSVIAFLAILKAGAVYVPLDPDHPADRVAYMLEDSGVSLVLTDRADLYPAQRSLDPTRPLPV
SETPAALPPSDPARIAYLLYTSGSTGRPNGVPIAHASLLNHLRSMAVSPGLAPGDRLLAITTPTFDISILEMLLPLSVGA
TTVLYGQDLLLAPQRLADVLVTDRISHLQATPAYWRMLIDSGWEGLPHLIALCGGEALDAPLARKLIDRTKELWNVYGPT
EATIWASALKVTHAHAESGKVPVGGLLDNTHLHVLDAYMQPLPRGIGGELYIGGPCLSPGYWNRPALTAARFVPNPFYDE
NSPALRLYRTGDAVVRLANSEIEFIGRTDFQVKLRGYRIEIGEIEDKLLRESVVEQAIVTLDAENERLIAYVLVRDWPTT
NDGEIERKLRQSLSAQLPRYMVPTAFVILEEFPLNPNGKVDRKQLPIPQLSTTRAEPIPARNAIEATLLEIWKAVLRRED
IGIEDNFFDLGGDSIIGVQIVAKAQAKGLKLEPTQIFELQTIAAQAIAAVAESAVHTIEVQAIEVAESGPSFEMTPVQAG
MLFHSLMAPASGTYIEQCWCVLEGTLDADAFKSAWGRVIARHEVLRGACRWTDVERPIMVIAEDVVPEWREADWSGEDAA
GQETAFAAWLEADRRRGFTLDAAPLLRFALIRLGPGRHRFVWSFHHLLMDGWCGSLLVGEMLKAYAGESLPAPPPSYRQY
VAWRDRQDITAAQAYWSHALADLPQGGFLGETKIGEAAQEAIIEIRRSLDASLATRLAAMARRERLTLATVLQGAWALLL
SRYGAEDDVIFGTVLSGRPPDLPDADRMIGLFLNTVPFRARTRPEERVAEWLQGLQSAHRQREKHGHAALADIQRWAGKT
ADQPLFDTLLIIENLPLSMQAAFAEGTHTLTLSDPGSYERTHYPLSLRIFPGAEIEIALAADPSRLSSTKADRLLRHYET
LLSSIADDPRACLGTIEMLKPDERDILLQTGRGPQTQPCAAVHDQIIARAKEEPGKAAVVQVGEGRDSTMSYGDLAGYAE
ALALRLYQQGIGRGAVVAVYLRRGSALLPSLLAVMRSGAAYLPIDPDYPAERIAYMLADSGAALVLTDLGDSERAVIPQD
VPVLDPTEAFGCAQASFEPAAVQADDLAYILYTSGSTGQPKGVAITHGALANFIESMADRPGIGADDRLLALTTIGFDIA
GLELFAPLSQGATVLLADSAIARDGRRLAALVDRVQPSVMQATPAGWRMLIEAGWRGSQELRMLCGGEALDSLLAAELLD
RGDCLWNLYGPTETTIWSAATEVRREDLNGHSVTVAGPIQNTQLYVLDRRGEPVPPGTPGELHIGGAGLSPGYWGKPGLT
ADRFIPNPFRRGPQDGYHLYRTGDLVRLAENGALDFLGRIDNQVKLRGYRIELGEVEARLAAHPRVAEAAVLVEDGGAGK
QLIAYLRWREPFVGDASAELGPHVAGSLPLYMLPSAYVALDAFPLTPNGKVDRRALPACRPKPAQRQTHLPISGEPAATL
AAIWREALKIDHVNPGDNFFECGGHSLLVVSLQGVIGKRFGVSIDITAFFQFPTLETLAAHIAQLQAGREGQWSGGDRTL
LRQTGRDRLAGRRGLRAERTGA

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=435, Percent_Identity=26.8965517241379, Blast_Score=117, Evalue=2e-25,
Organism=Homo sapiens, GI187761345, Length=471, Percent_Identity=26.7515923566879, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI187761343, Length=471, Percent_Identity=26.7515923566879, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI156151445, Length=544, Percent_Identity=22.7941176470588, Blast_Score=95, Evalue=8e-19,
Organism=Homo sapiens, GI38505220, Length=452, Percent_Identity=24.5575221238938, Blast_Score=91, Evalue=2e-17,
Organism=Homo sapiens, GI122937307, Length=530, Percent_Identity=25.2830188679245, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI115511026, Length=520, Percent_Identity=25.1923076923077, Blast_Score=89, Evalue=7e-17,
Organism=Homo sapiens, GI157311624, Length=501, Percent_Identity=23.1536926147705, Blast_Score=87, Evalue=2e-16,
Organism=Homo sapiens, GI157311622, Length=501, Percent_Identity=23.1536926147705, Blast_Score=87, Evalue=2e-16,
Organism=Homo sapiens, GI58082049, Length=508, Percent_Identity=22.244094488189, Blast_Score=82, Evalue=7e-15,
Organism=Escherichia coli, GI1786801, Length=1072, Percent_Identity=28.544776119403, Blast_Score=300, Evalue=8e-82,
Organism=Escherichia coli, GI145693145, Length=531, Percent_Identity=24.8587570621469, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1788107, Length=560, Percent_Identity=25.3571428571429, Blast_Score=100, Evalue=8e-22,
Organism=Escherichia coli, GI1790505, Length=623, Percent_Identity=25.8426966292135, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1786810, Length=504, Percent_Identity=25.5952380952381, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI221142682, Length=188, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17556356, Length=557, Percent_Identity=28.3662477558348, Blast_Score=151, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17550940, Length=1043, Percent_Identity=22.5311601150527, Blast_Score=151, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32564422, Length=424, Percent_Identity=24.5283018867925, Blast_Score=99, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32564420, Length=424, Percent_Identity=24.5283018867925, Blast_Score=99, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994703, Length=561, Percent_Identity=21.0338680926916, Blast_Score=88, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994694, Length=561, Percent_Identity=21.0338680926916, Blast_Score=87, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994690, Length=561, Percent_Identity=21.0338680926916, Blast_Score=87, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17558820, Length=467, Percent_Identity=23.5546038543897, Blast_Score=82, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17557194, Length=546, Percent_Identity=22.7106227106227, Blast_Score=81, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32563687, Length=525, Percent_Identity=23.4285714285714, Blast_Score=81, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=540, Percent_Identity=21.2962962962963, Blast_Score=79, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983001, Length=536, Percent_Identity=23.3208955223881, Blast_Score=73, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982997, Length=536, Percent_Identity=23.3208955223881, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531443, Length=563, Percent_Identity=23.4458259325044, Blast_Score=72, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=742, Percent_Identity=26.010781671159, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24648676, Length=586, Percent_Identity=31.9112627986348, Blast_Score=209, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24581924, Length=540, Percent_Identity=23.8888888888889, Blast_Score=92, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24582852, Length=532, Percent_Identity=23.8721804511278, Blast_Score=91, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 238694; Mature: 238562

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00141 ASP_PROTEASE ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNSADPILALRARVAALSPAEREAFRRQLEARGIAWERVAPEETPQETSRVSTRPARL
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHCCCCCCCC
PLTPGQKHFWLQQSLYPESSAYHVAYRWRFEGPLDRAALERSLATIVSRHAPLRTAFPVE
CCCCCCCCEEHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEECCCC
AGEPWQEVHPDHAFALGFTDLEATGEDGEALALAVATEPFDLSKAPLIRAHLFRQHESEH
CCCCHHHCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
LLAITLHHIVADGWSRGVLMRELTACYRAYRMGAAPALSHITRDFGDLVLDQHAWLQRRD
EEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
CGRDRDYWKQTLADLKPLELPSDRSRSSSVDMTAATVTRVIPVSVSSQVASLASQLGTTP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEECCHHHHHHHHHHHHCCCH
FVVMAAAFSLLLHRYSGERDLSVCVPVAGRDNPDAAGLIGLFTNTLVLRAQLDPRMTFSQ
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCEEEEEEECCCCCCHHH
WVGAVQERFSDALDHQAFPFPLIAEALGMSRDQRQSPLSQVMFQLQSQDYRAQNAEQIDF
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCCCCCCEEEC
GIDGLIVRQQPARLSETKVDLSWYVMERESGYLLNIEYRVAIFDAWRIERMAAHFEVLLG
CCCEEEEECCCCCCCCCEEEEEEEEEECCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHH
SILQSPNALLPRLAYLSKEEHATVVALGTPTARPVPDITMHDAIAHVARHQPDAIALESK
HHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECC
GQSWTYGELQKDVDALTDTLVGLSVHPGDRVAVSLPGRGQSVIAFLAILKAGAVYVPLDP
CCCCCHHHHHHHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCC
DHPADRVAYMLEDSGVSLVLTDRADLYPAQRSLDPTRPLPVSETPAALPPSDPARIAYLL
CCCHHHEEEEEECCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
YTSGSTGRPNGVPIAHASLLNHLRSMAVSPGLAPGDRLLAITTPTFDISILEMLLPLSVG
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
ATTVLYGQDLLLAPQRLADVLVTDRISHLQATPAYWRMLIDSGWEGLPHLIALCGGEALD
CEEEEECCCHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCC
APLARKLIDRTKELWNVYGPTEATIWASALKVTHAHAESGKVPVGGLLDNTHLHVLDAYM
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
QPLPRGIGGELYIGGPCLSPGYWNRPALTAARFVPNPFYDENSPALRLYRTGDAVVRLAN
HHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEC
SEIEFIGRTDFQVKLRGYRIEIGEIEDKLLRESVVEQAIVTLDAENERLIAYVLVRDWPT
CCEEEEECCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEECCCC
TNDGEIERKLRQSLSAQLPRYMVPTAFVILEEFPLNPNGKVDRKQLPIPQLSTTRAEPIP
CCCHHHHHHHHHHHHHHCCHHHCCHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARNAIEATLLEIWKAVLRREDIGIEDNFFDLGGDSIIGVQIVAKAQAKGLKLEPTQIFEL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEEEEEEHHHCCCCCCCHHHHHH
QTIAAQAIAAVAESAVHTIEVQAIEVAESGPSFEMTPVQAGMLFHSLMAPASGTYIEQCW
HHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEECHHHHHHHHHHHHCCCCCCHHHHHH
CVLEGTLDADAFKSAWGRVIARHEVLRGACRWTDVERPIMVIAEDVVPEWREADWSGEDA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCHHHCCCCCCCCC
AGQETAFAAWLEADRRRGFTLDAAPLLRFALIRLGPGRHRFVWSFHHLLMDGWCGSLLVG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHH
EMLKAYAGESLPAPPPSYRQYVAWRDRQDITAAQAYWSHALADLPQGGFLGETKIGEAAQ
HHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
EAIIEIRRSLDASLATRLAAMARRERLTLATVLQGAWALLLSRYGAEDDVIFGTVLSGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
PDLPDADRMIGLFLNTVPFRARTRPEERVAEWLQGLQSAHRQREKHGHAALADIQRWAGK
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
TADQPLFDTLLIIENLPLSMQAAFAEGTHTLTLSDPGSYERTHYPLSLRIFPGAEIEIAL
CCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCCCCCEECCEEEEEECCCCEEEEE
AADPSRLSSTKADRLLRHYETLLSSIADDPRACLGTIEMLKPDERDILLQTGRGPQTQPC
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCH
AAVHDQIIARAKEEPGKAAVVQVGEGRDSTMSYGDLAGYAEALALRLYQQGIGRGAVVAV
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
YLRRGSALLPSLLAVMRSGAAYLPIDPDYPAERIAYMLADSGAALVLTDLGDSERAVIPQ
EECCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
DVPVLDPTEAFGCAQASFEPAAVQADDLAYILYTSGSTGQPKGVAITHGALANFIESMAD
CCCCCCCHHHHCCCCCCCCCCEEECCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHC
RPGIGADDRLLALTTIGFDIAGLELFAPLSQGATVLLADSAIARDGRRLAALVDRVQPSV
CCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCHH
MQATPAGWRMLIEAGWRGSQELRMLCGGEALDSLLAAELLDRGDCLWNLYGPTETTIWSA
HHCCCCHHEEHEECCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
ATEVRREDLNGHSVTVAGPIQNTQLYVLDRRGEPVPPGTPGELHIGGAGLSPGYWGKPGL
HHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
TADRFIPNPFRRGPQDGYHLYRTGDLVRLAENGALDFLGRIDNQVKLRGYRIELGEVEAR
CHHCCCCCHHHCCCCCCCEEEECCCEEEEECCCCHHHHHHCCCEEEEEEEEEEHHHHHHH
LAAHPRVAEAAVLVEDGGAGKQLIAYLRWREPFVGDASAELGPHVAGSLPLYMLPSAYVA
HHCCCCHHEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCEEE
LDAFPLTPNGKVDRRALPACRPKPAQRQTHLPISGEPAATLAAIWREALKIDHVNPGDNF
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCH
FECGGHSLLVVSLQGVIGKRFGVSIDITAFFQFPTLETLAAHIAQLQAGREGQWSGGDRT
HHCCCCEEEEEEECHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHH
LLRQTGRDRLAGRRGLRAERTGA
HHHHCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PVNSADPILALRARVAALSPAEREAFRRQLEARGIAWERVAPEETPQETSRVSTRPARL
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHCCCCCCCC
PLTPGQKHFWLQQSLYPESSAYHVAYRWRFEGPLDRAALERSLATIVSRHAPLRTAFPVE
CCCCCCCCEEHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEECCCC
AGEPWQEVHPDHAFALGFTDLEATGEDGEALALAVATEPFDLSKAPLIRAHLFRQHESEH
CCCCHHHCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCC
LLAITLHHIVADGWSRGVLMRELTACYRAYRMGAAPALSHITRDFGDLVLDQHAWLQRRD
EEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
CGRDRDYWKQTLADLKPLELPSDRSRSSSVDMTAATVTRVIPVSVSSQVASLASQLGTTP
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEECCHHHHHHHHHHHHCCCH
FVVMAAAFSLLLHRYSGERDLSVCVPVAGRDNPDAAGLIGLFTNTLVLRAQLDPRMTFSQ
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCEEEEEEECCCCCCHHH
WVGAVQERFSDALDHQAFPFPLIAEALGMSRDQRQSPLSQVMFQLQSQDYRAQNAEQIDF
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCCCCCCEEEC
GIDGLIVRQQPARLSETKVDLSWYVMERESGYLLNIEYRVAIFDAWRIERMAAHFEVLLG
CCCEEEEECCCCCCCCCEEEEEEEEEECCCCEEEEEEEEEEEEEHHHHHHHHHHHHHHHH
SILQSPNALLPRLAYLSKEEHATVVALGTPTARPVPDITMHDAIAHVARHQPDAIALESK
HHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECC
GQSWTYGELQKDVDALTDTLVGLSVHPGDRVAVSLPGRGQSVIAFLAILKAGAVYVPLDP
CCCCCHHHHHHHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCC
DHPADRVAYMLEDSGVSLVLTDRADLYPAQRSLDPTRPLPVSETPAALPPSDPARIAYLL
CCCHHHEEEEEECCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
YTSGSTGRPNGVPIAHASLLNHLRSMAVSPGLAPGDRLLAITTPTFDISILEMLLPLSVG
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
ATTVLYGQDLLLAPQRLADVLVTDRISHLQATPAYWRMLIDSGWEGLPHLIALCGGEALD
CEEEEECCCHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCC
APLARKLIDRTKELWNVYGPTEATIWASALKVTHAHAESGKVPVGGLLDNTHLHVLDAYM
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
QPLPRGIGGELYIGGPCLSPGYWNRPALTAARFVPNPFYDENSPALRLYRTGDAVVRLAN
HHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEC
SEIEFIGRTDFQVKLRGYRIEIGEIEDKLLRESVVEQAIVTLDAENERLIAYVLVRDWPT
CCEEEEECCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEECCCC
TNDGEIERKLRQSLSAQLPRYMVPTAFVILEEFPLNPNGKVDRKQLPIPQLSTTRAEPIP
CCCHHHHHHHHHHHHHHCCHHHCCHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARNAIEATLLEIWKAVLRREDIGIEDNFFDLGGDSIIGVQIVAKAQAKGLKLEPTQIFEL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEEEEEEHHHCCCCCCCHHHHHH
QTIAAQAIAAVAESAVHTIEVQAIEVAESGPSFEMTPVQAGMLFHSLMAPASGTYIEQCW
HHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEECHHHHHHHHHHHHCCCCCCHHHHHH
CVLEGTLDADAFKSAWGRVIARHEVLRGACRWTDVERPIMVIAEDVVPEWREADWSGEDA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCHHHCCCCCCCCC
AGQETAFAAWLEADRRRGFTLDAAPLLRFALIRLGPGRHRFVWSFHHLLMDGWCGSLLVG
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHH
EMLKAYAGESLPAPPPSYRQYVAWRDRQDITAAQAYWSHALADLPQGGFLGETKIGEAAQ
HHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
EAIIEIRRSLDASLATRLAAMARRERLTLATVLQGAWALLLSRYGAEDDVIFGTVLSGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
PDLPDADRMIGLFLNTVPFRARTRPEERVAEWLQGLQSAHRQREKHGHAALADIQRWAGK
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
TADQPLFDTLLIIENLPLSMQAAFAEGTHTLTLSDPGSYERTHYPLSLRIFPGAEIEIAL
CCCCHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCCCCCEECCEEEEEECCCCEEEEE
AADPSRLSSTKADRLLRHYETLLSSIADDPRACLGTIEMLKPDERDILLQTGRGPQTQPC
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCH
AAVHDQIIARAKEEPGKAAVVQVGEGRDSTMSYGDLAGYAEALALRLYQQGIGRGAVVAV
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
YLRRGSALLPSLLAVMRSGAAYLPIDPDYPAERIAYMLADSGAALVLTDLGDSERAVIPQ
EECCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
DVPVLDPTEAFGCAQASFEPAAVQADDLAYILYTSGSTGQPKGVAITHGALANFIESMAD
CCCCCCCHHHHCCCCCCCCCCEEECCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHC
RPGIGADDRLLALTTIGFDIAGLELFAPLSQGATVLLADSAIARDGRRLAALVDRVQPSV
CCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCHH
MQATPAGWRMLIEAGWRGSQELRMLCGGEALDSLLAAELLDRGDCLWNLYGPTETTIWSA
HHCCCCHHEEHEECCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
ATEVRREDLNGHSVTVAGPIQNTQLYVLDRRGEPVPPGTPGELHIGGAGLSPGYWGKPGL
HHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
TADRFIPNPFRRGPQDGYHLYRTGDLVRLAENGALDFLGRIDNQVKLRGYRIELGEVEAR
CHHCCCCCHHHCCCCCCCEEEECCCEEEEECCCCHHHHHHCCCEEEEEEEEEEHHHHHHH
LAAHPRVAEAAVLVEDGGAGKQLIAYLRWREPFVGDASAELGPHVAGSLPLYMLPSAYVA
HHCCCCHHEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCEEE
LDAFPLTPNGKVDRRALPACRPKPAQRQTHLPISGEPAATLAAIWREALKIDHVNPGDNF
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCH
FECGGHSLLVVSLQGVIGKRFGVSIDITAFFQFPTLETLAAHIAQLQAGREGQWSGGDRT
HHCCCCEEEEEEECHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHH
LLRQTGRDRLAGRRGLRAERTGA
HHHHCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]