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The map label for this gene is hupT [H]

Identifier: 222102443

GI number: 222102443

Start: 40213

End: 40491

Strand: Reverse

Name: hupT [H]

Synonym: Avi_7042

Alternate gene names: 222102443

Gene position: 40491-40213 (Counterclockwise)

Preceding gene: 222102447

Following gene: 222102442

Centisome position: 6.41

GC content: 56.27

Gene sequence:

>279_bases
ATGACCACCACCAATGAAATCGCCGACAAGATCGCCGCCAACAACGGCCTGACAAAGGTTCAGGCCAAGGGCATCGTCGA
ATCCGTGTTCAAGGCCATCGCCGACGCCGCAGGCTCCGACGCGGAAACGTCAATCCCCGGTTTCGGCAAATTTAAGGTGA
AAACATCACCTGAGCGCGAGGGTCGCAATCCCGCGACCGGAGAAAAAATGACTGTTGCAGCTTCGAAGAAGCTGACTTTC
GCGCCTGCCAAGGCCCTCAAGGATGCACTGAACAAGTGA

Upstream 100 bases:

>100_bases
GTGACGCTCCTTGTCTCTCGCTGTTAATCGCGACAAACAGAATCTTCACCTTCACTCATAACCACAAGACGGCCTTCCTC
GGATACGTACGAGGAATCCC

Downstream 100 bases:

>100_bases
TCCCTGACGTGGAGAGCCCCGCCGCGAGGCGGGGCATCCAGTCTCAGTCCCGGTTCGACCGGGACCAGATGAGGGAGAGG
CCTTCCTCGCCTTCGACCTC

Product: HNS-type DNA binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MTTTNEIADKIAANNGLTKVQAKGIVESVFKAIADAAGSDAETSIPGFGKFKVKTSPEREGRNPATGEKMTVAASKKLTF
APAKALKDALNK

Sequences:

>Translated_92_residues
MTTTNEIADKIAANNGLTKVQAKGIVESVFKAIADAAGSDAETSIPGFGKFKVKTSPEREGRNPATGEKMTVAASKKLTF
APAKALKDALNK
>Mature_91_residues
TTTNEIADKIAANNGLTKVQAKGIVESVFKAIADAAGSDAETSIPGFGKFKVKTSPEREGRNPATGEKMTVAASKKLTFA
PAKALKDALNK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=85, Percent_Identity=41.1764705882353, Blast_Score=63, Evalue=4e-12,
Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=36.7816091954023, Blast_Score=62, Evalue=7e-12,
Organism=Escherichia coli, GI1788005, Length=85, Percent_Identity=35.2941176470588, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9566; Mature: 9435

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTNEIADKIAANNGLTKVQAKGIVESVFKAIADAAGSDAETSIPGFGKFKVKTSPERE
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
GRNPATGEKMTVAASKKLTFAPAKALKDALNK
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TTTNEIADKIAANNGLTKVQAKGIVESVFKAIADAAGSDAETSIPGFGKFKVKTSPERE
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
GRNPATGEKMTVAASKKLTFAPAKALKDALNK
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]