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The map label for this gene is trpF [H]

Identifier: 222094965

GI number: 222094965

Start: 1292673

End: 1293287

Strand: Direct

Name: trpF [H]

Synonym: BCQ_1303

Alternate gene names: 222094965

Gene position: 1292673-1293287 (Clockwise)

Preceding gene: 222094964

Following gene: 222094966

Centisome position: 24.79

GC content: 37.24

Gene sequence:

>615_bases
ATGAAAGTGAAAATTTGCGGGATCACTGATATGGAAACAGCAAAACGTGCTTGCGAATACGGAGCTGATGCACTCGGATT
TGTTTTTGCAGAAAGTAAGAGAAAAATTACTCCAGGGCTAGCGAAAGAAATCATTCAGGAACTTCCAGCCAACGTGTTAA
AAATCGGTGTTTTCGTAAATGAATCAGTAGAAGTAATCCAGAAAATTACAGAGAATTGCGGGTTAACACATGTGCAACTA
CATGGGGACGAAGATAATCATCAGATTAGAAGATTGAATATTCCGTCTATAAAAGCGCTCGGAGTAACTTCAGAGATTGA
TATGAAAAATGCTCAAGCATATAAAACGGATTATATATTGTTTGATAGCCCAAAAGAAAGGTTTCACGGAGGAAATGGAA
AGAAATTTTCATGGGAACTACTCGCACATATGTCAAAAGAGTTGCGAGAGAAAACGATATTAGCTGGTGGATTAAATGCT
CTTAATATAGAAGAAGCAATTCGAACTGTTCGGCCATATATGGTCGATGTGAGCAGCGGAGTAGAGACAGAAGGAAAGAA
AGATGTAGAGAAAATAAAACAATTTATTATAAAAGCGAAGGAGTGTTCTAAATGA

Upstream 100 bases:

>100_bases
TCCGCGTTAAACGAGCTGGGGCAAAAGGTGTACTAGTTGGAGAAGCGCTTATGACATCGTCTTCTATTCATACCTTTTTT
GAAGATTGTAAGGTGAACAT

Downstream 100 bases:

>100_bases
ACTACGCATATCCAGATGAAAAAGGTCACTACGGTATATACGGAGGACGATACGTTCCAGAAACGTTAATGCAATCTGTA
TTAGAACTAGAAGAAGCATA

Product: n-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITENCGLTHVQL
HGDEDNHQIRRLNIPSIKALGVTSEIDMKNAQAYKTDYILFDSPKERFHGGNGKKFSWELLAHMSKELREKTILAGGLNA
LNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK

Sequences:

>Translated_204_residues
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITENCGLTHVQL
HGDEDNHQIRRLNIPSIKALGVTSEIDMKNAQAYKTDYILFDSPKERFHGGNGKKFSWELLAHMSKELREKTILAGGLNA
LNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK
>Mature_204_residues
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITENCGLTHVQL
HGDEDNHQIRRLNIPSIKALGVTSEIDMKNAQAYKTDYILFDSPKERFHGGNGKKFSWELLAHMSKELREKTILAGGLNA
LNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=193, Percent_Identity=32.6424870466321, Blast_Score=67, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320210, Length=215, Percent_Identity=33.0232558139535, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 22778; Mature: 22778

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVN
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCHHHEEEHHHCC
ESVEVIQKITENCGLTHVQLHGDEDNHQIRRLNIPSIKALGVTSEIDMKNAQAYKTDYIL
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCCCEECEEEE
FDSPKERFHGGNGKKFSWELLAHMSKELREKTILAGGLNALNIEEAIRTVRPYMVDVSSG
ECCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCCC
VETEGKKDVEKIKQFIIKAKECSK
CCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVN
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCHHHEEEHHHCC
ESVEVIQKITENCGLTHVQLHGDEDNHQIRRLNIPSIKALGVTSEIDMKNAQAYKTDYIL
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCCCEECEEEE
FDSPKERFHGGNGKKFSWELLAHMSKELREKTILAGGLNALNIEEAIRTVRPYMVDVSSG
ECCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCCC
VETEGKKDVEKIKQFIIKAKECSK
CCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA