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The map label for this gene is trpB [H]

Identifier: 222094966

GI number: 222094966

Start: 1293284

End: 1294477

Strand: Direct

Name: trpB [H]

Synonym: BCQ_1304

Alternate gene names: 222094966

Gene position: 1293284-1294477 (Clockwise)

Preceding gene: 222094965

Following gene: 222094967

Centisome position: 24.8

GC content: 41.29

Gene sequence:

>1194_bases
ATGAACTACGCATATCCAGATGAAAAAGGTCACTACGGTATATACGGAGGACGATACGTTCCAGAAACGTTAATGCAATC
TGTATTAGAACTAGAAGAAGCATATAAAGAGGCAATGGAAGATGAAGAGTTTCAAAAGGAATTAAATCATTATTTAAAAA
CGTATGTCGGAAGAGAAACGCCGCTTTATTTCGCTGAGAATATGACGAAGTATTGCGGTGGTGCAAAGATTTATTTAAAA
CGTGAAGATTTGAACCATACAGGAGCTCATAAAATTAATAATACAATCGGTCAGGCACTTCTTGCGGTGCGAATGGGCAA
GAAAAAAGTTGTCGCTGAAACAGGAGCTGGACAACACGGAGTTGCAACAGCTACTGTATGTGCCCTTCTCGGTTTAGAAT
GCGTCATTTTTATGGGAGAAGAAGATGTAAGACGTCAAAAATTAAATGTGTTCCGAATGGAATTACTCGGAGCGAAAGTA
GAAAGTGTAGCAGCAGGTAGCGGTACATTAAAAGATGCGGTAAACGAGGCGCTTCGCTACTGGGTTTCACATGTGCATGA
TACGCACTACATTATGGGATCTGTTCTCGGACCACATCCATTCCCGCAAATTGTCCGTGATTTCCAAAGTGTAATTGGAA
ATGAAACGAAAAAACAATATGAAGCATTAGAAGGAAAGTTACCAGAAGCAGTCGTTGCTTGTATTGGCGGTGGTAGTAAT
GCGATGGGTATGTTTTATCCGTTCGTACACGATGAAGAAGTTGCTCTTTACGGCGTAGAAGCAGCTGGAAAAGGAGTTCA
TACAGAAAAGCATGCAGCTACTTTAACGAAAGGAAGCGTTGGCGTTCTCCACGGATCGATGATGTATCTTCTGCAAAATG
AAGAAGGACAAATTCAAGAAGCTCACTCTATTTCGGCGGGACTTGATTACCCTGGTGTTGGGCCAGAACATAGCTTGCTA
AAAGATATTGGCCGCGTTTCTTATCATTCCATTACTGATGATGAAGCGTTAGAAGCATTTCAATTATTAACGAAAAAAGA
AGGAATTATCCCGGCGTTAGAAAGCTCGCATGCTGTCGCGTACGCTTTAAAATTAGCGCCGCAAATGAAGAAAGACGAAG
GGCTTGTCATTTGTTTATCTGGCCGCGGTGATAAAGATGTAGAGAGTATAAAACGTTATATGGAAGAGGTGTAA

Upstream 100 bases:

>100_bases
GGCCATATATGGTCGATGTGAGCAGCGGAGTAGAGACAGAAGGAAAGAAAGATGTAGAGAAAATAAAACAATTTATTATA
AAAGCGAAGGAGTGTTCTAA

Downstream 100 bases:

>100_bases
ACAATGGGAGTAGAAAAAATGAAAGCAGCATTTGAAAATGGCAAGAAAGCATTTATTCCGTACGTAATGGGCGGAGATGG
TGGCCTTGAAAAATTAAAAG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEEFQKELNHYLKTYVGRETPLYFAENMTKYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV

Sequences:

>Translated_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEEFQKELNHYLKTYVGRETPLYFAENMTKYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
>Mature_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEEFQKELNHYLKTYVGRETPLYFAENMTKYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=55.3805774278215, Blast_Score=425, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=57.7319587628866, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43646; Mature: 43646

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEEFQKELNHYLKTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
PLYFAENMTKYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEEFQKELNHYLKTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
PLYFAENMTKYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA