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The map label for this gene is yvmA [H]

Identifier: 222094495

GI number: 222094495

Start: 820683

End: 821864

Strand: Reverse

Name: yvmA [H]

Synonym: BCQ_0833

Alternate gene names: 222094495

Gene position: 821864-820683 (Counterclockwise)

Preceding gene: 222094503

Following gene: 222094477

Centisome position: 15.76

GC content: 34.01

Gene sequence:

>1182_bases
ATGAAAAAATCCAAACTACATTTCATTTTATATGTTGTCTGTATTAGTGCCTTACTTGGTTCCTTCGCTCAAAATATTTA
CACACCTATCTTGCCCATGATTCAAGGTTCTTTTCATACTTCTCTTTATCTTGTAAATGTAACAGTTTCACTTTTCACAT
TCATTCTTGCAATTATGCAGCTCGTATATGGACCTTTAATTGATACAAAAGGGAGAAAATCTGTCCTTATCCCTAGTTTA
GTCATTAGTACAATTGGTTCAATCGGATGTGCTTTTTCGGCAAACATTTATTTATTTCTCTTTTTTAGAGCTGTTCAAGC
TATAGGAATAGCGGCTATACCTGTAGTTTCAGCAACGATTATCGGCGATTTATTTGAAGGAAAAGAACGCGGAGAAGCGA
TGAGCCTATACCAAATGTTACTTGCCCTCGCACCTGCGATTGGTCCTCTCATTGGTGGTTATCTCGGCAGTATAAATGGC
CACTTATCCGTATTTCTATTTTTATCTATACTTGGCATTCTTTTATTAATGATAAACCTTTCACTACTTCCAGAAACAAA
ACCTACTGTAATTAAGCAACCGCAAGCAAAAAAGAATTACTGGTTTATCTTAAAAAATAAAACTGGATTTTCTATTACTC
TTATTGGCTTCATTCAATTTTGTATTTACTTTTGCTTTCTCGTTTTTTTACCGAGTATTTTAACAAATTCATTTCATTTA
ACTGTAAATGAAATTGGTCTTATGTTTGTACCAATGTCTCTTTCTATCATGCTGGGAAGTTTTTGCTACAAGTTTTTGCA
AAAACGCCTCACAACAAAGCAAACTTTATTTATTACGAGTTTCTTCAAAATTATATGTGTCGTTTTATTCTCTTTCACAT
ATAGCATTAATATCCCATTCATCATTATCGTTACATCTTTGTACGGTTTTAGTATGGGACTTTCTATGCCAACTCACACT
ACTTTATTAACGGAAGAATTCGTACAAGAACGCGCAACAGCTATCGGTATGTACAACTTCATCCGCTATCTTGGTATGGG
CACAGGCCCACTTATAGGTGGATTTCTTTTATTTAACCAAAATTACTTTTGGATTTTCTTCCTAGGCGCAATTATGTTTT
TACTTGTAATCTTATATGCAATGAAAATGCTATGCTTCCCTGCCACACAAAAAGCAAAATAG

Upstream 100 bases:

>100_bases
ATATACCATTTTAAAATCATTTTTTCATATTTACAAGTGAGAAAAACATGTTAAAATAAATTTAGTTTCCAAGGAAACTA
AAAAGGAGGAGGTTAACATA

Downstream 100 bases:

>100_bases
AGACCTACAGATGGTCTCTATTTTAAACTCTTTGATCCGCAACAATATGAATATCAATATGTTTCGTCTGTCTCATAATT
TCATTTACAATAGAACCTTT

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKKSKLHFILYVVCISALLGSFAQNIYTPILPMIQGSFHTSLYLVNVTVSLFTFILAIMQLVYGPLIDTKGRKSVLIPSL
VISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HLSVFLFLSILGILLLMINLSLLPETKPTVIKQPQAKKNYWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFHL
TVNEIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQTLFITSFFKIICVVLFSFTYSINIPFIIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQNYFWIFFLGAIMFLLVILYAMKMLCFPATQKAK

Sequences:

>Translated_393_residues
MKKSKLHFILYVVCISALLGSFAQNIYTPILPMIQGSFHTSLYLVNVTVSLFTFILAIMQLVYGPLIDTKGRKSVLIPSL
VISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HLSVFLFLSILGILLLMINLSLLPETKPTVIKQPQAKKNYWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFHL
TVNEIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQTLFITSFFKIICVVLFSFTYSINIPFIIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQNYFWIFFLGAIMFLLVILYAMKMLCFPATQKAK
>Mature_393_residues
MKKSKLHFILYVVCISALLGSFAQNIYTPILPMIQGSFHTSLYLVNVTVSLFTFILAIMQLVYGPLIDTKGRKSVLIPSL
VISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HLSVFLFLSILGILLLMINLSLLPETKPTVIKQPQAKKNYWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFHL
TVNEIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQTLFITSFFKIICVVLFSFTYSINIPFIIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQNYFWIFFLGAIMFLLVILYAMKMLCFPATQKAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=269, Percent_Identity=29.368029739777, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790146, Length=183, Percent_Identity=26.2295081967213, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082312, Length=359, Percent_Identity=22.8412256267409, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788509, Length=246, Percent_Identity=24.7967479674797, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322071, Length=292, Percent_Identity=26.027397260274, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324264, Length=170, Percent_Identity=31.1764705882353, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322070, Length=269, Percent_Identity=26.7657992565056, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319657, Length=399, Percent_Identity=22.8070175438596, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319517, Length=189, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325414, Length=407, Percent_Identity=21.1302211302211, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321577, Length=407, Percent_Identity=20.6388206388206, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43852; Mature: 43852

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKLHFILYVVCISALLGSFAQNIYTPILPMIQGSFHTSLYLVNVTVSLFTFILAIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHHHHHHHHHHHHHH
LVYGPLIDTKGRKSVLIPSLVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATI
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHLSVFLFLSILGILLLMINL
HHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLLPETKPTVIKQPQAKKNYWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFHL
HHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEE
TVNEIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQTLFITSFFKIICVVLFSFTYSINIPF
EHHHHCHHEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECC
NYFWIFFLGAIMFLLVILYAMKMLCFPATQKAK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKSKLHFILYVVCISALLGSFAQNIYTPILPMIQGSFHTSLYLVNVTVSLFTFILAIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHHHHHHHHHHHHHH
LVYGPLIDTKGRKSVLIPSLVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATI
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHLSVFLFLSILGILLLMINL
HHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLLPETKPTVIKQPQAKKNYWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFHL
HHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEE
TVNEIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQTLFITSFFKIICVVLFSFTYSINIPF
EHHHHCHHEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECC
NYFWIFFLGAIMFLLVILYAMKMLCFPATQKAK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]