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The map label for this gene is rtcB [C]

Identifier: 221636031

GI number: 221636031

Start: 614283

End: 615743

Strand: Reverse

Name: rtcB [C]

Synonym: trd_A0625

Alternate gene names: 221636031

Gene position: 615743-614283 (Counterclockwise)

Preceding gene: 221636032

Following gene: 221636030

Centisome position: 67.09

GC content: 62.01

Gene sequence:

>1461_bases
ATGAATCGAGCACTGCACGTGCGGAAGATCCATGAGTATCTTTTCGAGATCCCGCCGCACGGCAAGATGCGCGTTCCGGC
CAGACTGTATCTCGACGAGCGCTCGCTGCGCGAACTGATGGAGAACCAGAGCAGCGAAGAGTGGAATGCGCTCAAGCAAC
TGGAAAACGTGGCGTGCTTGCCGGGAATCGTCAAGGCAGCGATGGCGATGGCGGACGTCCATCCCGGCTATGGCTTCCCA
ATCGGGGGTGTAGCGGCCTTCGATCCAAAAGATGGAGGCGTGATCAGCGTCGCCGGGGTGGGATTCGATATCAACTGCGG
CGTGCGTTGCTTGCGCACTCACCTCACACGCCGCGACCTGACAGGGAAAGAGGAGAAGTTGGCAGATACGATGTTCGAAG
TGATCCCGGCAGGTCTCGGCAGTACCGGGGAACTGAAGCTTTCGACGAAAGAGATCGACCGTGTCCTCCGGGAAGGGGCG
CGGTACGCGGTTCGGCTCGGCTACGGGCGCGAGGACGATTTGGAGTACATCGAGGAGCATGGCTGTCTCAGCGATGCTGA
TCCCTCAGTCGTCAGCCATACGGCCAAGCAGCGGCAGATGGCGCAGGTGGGAACGCTCGGCTCGGGAAACCACTACGTCG
AAGTACAGGTGGTGGACCAGATCTACAACGCGCGCGCAGCGGAAGCGTTCGGGCTGGAATTGGGACAGATCGTGATCATG
CTACACACCGGCAGCCGGGCACTCGGGCACCAGATCGGGACCGATTATCTCCCGTTCCTGGAGAAAGCGACCCGGAAGTA
CGGAATCGAGGTACCGGATCGGGAACTGGTGTGTGCACCGATCGAGAGTCCGGAGGGCCAGCAATATTTCAGGGCAGTGA
TGGCGGGAGCGAACTGTGCGTTCGCCAACCGGCAGGTGCTCGCGCATCTCGTGCGTCAGGCCTTTTGGAAGGCGTTGCGT
GTGCCCGATACGGCGATCGAAACGCTCTATGAGGTGGCACACAACACCGTGAAGTGGGAGGTGCATGAGGTGAATGGTGA
GCGCCGCCGACTGCTCGTCCATCGCAAGGGTTCGACGCGCGCCTTCGGGCCAGGACGCCCGGAACTTCCGGAGCGGTATC
GAGCAGTGGGGCAGCCCGTCCTGGTGGGCGGGACGATGGGTACGGCGAGCTACATTCTGGTGGGTACCGAGCAGGGTATG
CGAGAGACGTTCGGAACGGCCCTGCATGGTGCCGGGCGAGCGAAGTCCCGGCGTCAGGCGAAGCGCCAGTATCCGGCTGA
GCGGATCATCGAAGAGCTGCGCAAGCAGGGGATCATCGTCCGAGCCCACGGGAAGGCTTCGATCAGCGAGGAAGCGCCCG
GAGCCTACAAGGATGTCGAACATGTGGTCGAGGTAATGTGCAATGCCGGTATCGTGGCGCGTGTCGCCCGGTTGCGCCCG
ATCGTCTGCCTGAAGGGGTGA

Upstream 100 bases:

>100_bases
CCTACGGCGGATTGCTCGCCGAGGAGAACGAGGCAGGTTGGCGCTTGCGCTGCGTGCTCGATCTCTGACCGGCTGTACCG
CGTAACTGGGAGGGAGAACC

Downstream 100 bases:

>100_bases
GACGATGGGTGATGACCGGCGTATGGCCTTCCTGTTCGATCTGGACGGCACACTCGTCGATTCGGTCTACCAGCATGTCG
TGGCCTGGCGGGAAGCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNRALHVRKIHEYLFEIPPHGKMRVPARLYLDERSLRELMENQSSEEWNALKQLENVACLPGIVKAAMAMADVHPGYGFP
IGGVAAFDPKDGGVISVAGVGFDINCGVRCLRTHLTRRDLTGKEEKLADTMFEVIPAGLGSTGELKLSTKEIDRVLREGA
RYAVRLGYGREDDLEYIEEHGCLSDADPSVVSHTAKQRQMAQVGTLGSGNHYVEVQVVDQIYNARAAEAFGLELGQIVIM
LHTGSRALGHQIGTDYLPFLEKATRKYGIEVPDRELVCAPIESPEGQQYFRAVMAGANCAFANRQVLAHLVRQAFWKALR
VPDTAIETLYEVAHNTVKWEVHEVNGERRRLLVHRKGSTRAFGPGRPELPERYRAVGQPVLVGGTMGTASYILVGTEQGM
RETFGTALHGAGRAKSRRQAKRQYPAERIIEELRKQGIIVRAHGKASISEEAPGAYKDVEHVVEVMCNAGIVARVARLRP
IVCLKG

Sequences:

>Translated_486_residues
MNRALHVRKIHEYLFEIPPHGKMRVPARLYLDERSLRELMENQSSEEWNALKQLENVACLPGIVKAAMAMADVHPGYGFP
IGGVAAFDPKDGGVISVAGVGFDINCGVRCLRTHLTRRDLTGKEEKLADTMFEVIPAGLGSTGELKLSTKEIDRVLREGA
RYAVRLGYGREDDLEYIEEHGCLSDADPSVVSHTAKQRQMAQVGTLGSGNHYVEVQVVDQIYNARAAEAFGLELGQIVIM
LHTGSRALGHQIGTDYLPFLEKATRKYGIEVPDRELVCAPIESPEGQQYFRAVMAGANCAFANRQVLAHLVRQAFWKALR
VPDTAIETLYEVAHNTVKWEVHEVNGERRRLLVHRKGSTRAFGPGRPELPERYRAVGQPVLVGGTMGTASYILVGTEQGM
RETFGTALHGAGRAKSRRQAKRQYPAERIIEELRKQGIIVRAHGKASISEEAPGAYKDVEHVVEVMCNAGIVARVARLRP
IVCLKG
>Mature_486_residues
MNRALHVRKIHEYLFEIPPHGKMRVPARLYLDERSLRELMENQSSEEWNALKQLENVACLPGIVKAAMAMADVHPGYGFP
IGGVAAFDPKDGGVISVAGVGFDINCGVRCLRTHLTRRDLTGKEEKLADTMFEVIPAGLGSTGELKLSTKEIDRVLREGA
RYAVRLGYGREDDLEYIEEHGCLSDADPSVVSHTAKQRQMAQVGTLGSGNHYVEVQVVDQIYNARAAEAFGLELGQIVIM
LHTGSRALGHQIGTDYLPFLEKATRKYGIEVPDRELVCAPIESPEGQQYFRAVMAGANCAFANRQVLAHLVRQAFWKALR
VPDTAIETLYEVAHNTVKWEVHEVNGERRRLLVHRKGSTRAFGPGRPELPERYRAVGQPVLVGGTMGTASYILVGTEQGM
RETFGTALHGAGRAKSRRQAKRQYPAERIIEELRKQGIIVRAHGKASISEEAPGAYKDVEHVVEVMCNAGIVARVARLRP
IVCLKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=441, Percent_Identity=48.9795918367347, Blast_Score=427, Evalue=1e-119,
Organism=Escherichia coli, GI2367224, Length=444, Percent_Identity=30.8558558558559, Blast_Score=139, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17506665, Length=478, Percent_Identity=45.81589958159, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24585217, Length=495, Percent_Identity=44.8484848484849, Blast_Score=417, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 53699; Mature: 53699

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRALHVRKIHEYLFEIPPHGKMRVPARLYLDERSLRELMENQSSEEWNALKQLENVACL
CCCCHHHHHHHHHHHCCCCCCCEECCHHEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH
PGIVKAAMAMADVHPGYGFPIGGVAAFDPKDGGVISVAGVGFDINCGVRCLRTHLTRRDL
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCEECCCCHHHHHHHHHHHCC
TGKEEKLADTMFEVIPAGLGSTGELKLSTKEIDRVLREGARYAVRLGYGREDDLEYIEEH
CCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHC
GCLSDADPSVVSHTAKQRQMAQVGTLGSGNHYVEVQVVDQIYNARAAEAFGLELGQIVIM
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCHHHHHHCCCCCEEEEE
LHTGSRALGHQIGTDYLPFLEKATRKYGIEVPDRELVCAPIESPEGQQYFRAVMAGANCA
EECCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCH
FANRQVLAHLVRQAFWKALRVPDTAIETLYEVAHNTVKWEVHEVNGERRRLLVHRKGSTR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEECCCCC
AFGPGRPELPERYRAVGQPVLVGGTMGTASYILVGTEQGMRETFGTALHGAGRAKSRRQA
CCCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHH
KRQYPAERIIEELRKQGIIVRAHGKASISEEAPGAYKDVEHVVEVMCNAGIVARVARLRP
HHCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCC
IVCLKG
EEEECC
>Mature Secondary Structure
MNRALHVRKIHEYLFEIPPHGKMRVPARLYLDERSLRELMENQSSEEWNALKQLENVACL
CCCCHHHHHHHHHHHCCCCCCCEECCHHEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH
PGIVKAAMAMADVHPGYGFPIGGVAAFDPKDGGVISVAGVGFDINCGVRCLRTHLTRRDL
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCEECCCCHHHHHHHHHHHCC
TGKEEKLADTMFEVIPAGLGSTGELKLSTKEIDRVLREGARYAVRLGYGREDDLEYIEEH
CCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHC
GCLSDADPSVVSHTAKQRQMAQVGTLGSGNHYVEVQVVDQIYNARAAEAFGLELGQIVIM
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCHHHHHHCCCCCEEEEE
LHTGSRALGHQIGTDYLPFLEKATRKYGIEVPDRELVCAPIESPEGQQYFRAVMAGANCA
EECCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCH
FANRQVLAHLVRQAFWKALRVPDTAIETLYEVAHNTVKWEVHEVNGERRRLLVHRKGSTR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEECCCCC
AFGPGRPELPERYRAVGQPVLVGGTMGTASYILVGTEQGMRETFGTALHGAGRAKSRRQA
CCCCCCCCHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHH
KRQYPAERIIEELRKQGIIVRAHGKASISEEAPGAYKDVEHVVEVMCNAGIVARVARLRP
HHCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCC
IVCLKG
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA